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Additionally, changes in NEPA and estimated NEAT in those who failed (low-responders) or succeeded (high-responders) in attaining exercise-derived clinically meaningful reductions in body weight (BW) and fat mass (FM) (i.e., 6% for FM and 3% for BW) was assessed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Individuals with T2DM (<jats:italic>n<\/jats:italic>\u2009=\u200980) were enrolled in a RCT with three groups: resistance training combined with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) and a control group. Of the 80 participants, 56 (completed data) were considered for this secondary analysis. NEPA and estimated NEAT were obtained by accelerometry and body composition through dual-energy X-ray absorptiometry.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>After adjustments, no time*group interactions were found for estimated NEAT in the MICT (\u03b2\u2009=\u2009\u2212 5.33, <jats:italic>p<\/jats:italic>\u2009=\u20090.366) and HIIT (\u03b2\u2009=\u2009\u2212 5.70, <jats:italic>p<\/jats:italic>\u2009=\u20090.283), as well as for NEPA in the MICT (\u03b2\u2009=\u2009\u2212 452.83, <jats:italic>p<\/jats:italic>\u2009=\u20090.833) and HIIT (\u03b2\u2009=\u2009\u2212 2770.76, <jats:italic>p<\/jats:italic>\u2009=\u20090.201), when compared to controls. No compensatory changes in NEPA and estimated NEAT were observed when considering both low-responders and high-responders to FM and BW when compared to controls.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Both MICT and HIIT did not result in any compensatory changes in estimated NEAT and NEPA with the intervention on non-training days. Moreover, no changes in estimated NEAT and NEPA were found when categorizing our participants as low-responders and high-responders to FM and BW when compared to controls.<\/jats:p>\n                <jats:p>Trial registration clinicaltrials.gov ID.<\/jats:p>\n                <jats:p>NCT03144505.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00592-023-02038-7","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T12:07:01Z","timestamp":1675339621000},"page":"645-654","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Compensatory mechanisms from different exercise intensities in type 2 diabetes: a secondary analysis of a 1-year randomized controlled trial"],"prefix":"10.1007","volume":"60","author":[{"given":"In\u00eas R.","family":"Correia","sequence":"first","affiliation":[]},{"given":"Megan","family":"Hetherington-Rauth","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o P.","family":"Magalh\u00e3es","sequence":"additional","affiliation":[]},{"given":"Pedro B.","family":"J\u00fadice","sequence":"additional","affiliation":[]},{"given":"Gil B.","family":"Rosa","sequence":"additional","affiliation":[]},{"given":"Duarte","family":"Henriques-Neto","sequence":"additional","affiliation":[]},{"given":"Asier","family":"Manas","sequence":"additional","affiliation":[]},{"given":"Ignacio","family":"Ara","sequence":"additional","affiliation":[]},{"given":"Analiza M.","family":"Silva","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6230-6027","authenticated-orcid":false,"given":"Lu\u00eds B.","family":"Sardinha","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,2,2]]},"reference":[{"key":"2038_CR1","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1159\/000357338","volume":"60","author":"JH Goedecke","year":"2014","unstructured":"Goedecke JH, Micklesfield LK (2014) The effect of exercise on obesity, body fat distribution and risk for type 2 diabetes. 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