{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:11:57Z","timestamp":1771672317982,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T00:00:00Z","timestamp":1620172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T00:00:00Z","timestamp":1620172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Institut Straumann AG"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>The aim of this study was to assess the influence of transgingival compared with submerged healing on peri-implant bone maintenance around a novel, fully tapered implant in a healed crestal ridge in minipigs.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>In each of 12 minipigs, two implants (Straumann\u00ae BLX, Roxolid\u00ae SLActive\u00ae, \u00d8 3.75 \u00d7 8 mm) were placed. Implants were either left for submerged or for transgingival healing for 12 weeks. Measurements performed were bone-to-implant contact (BIC), first bone-to-implant contact (fBIC), bone area to total area (BATA), perpendicular bone crest to implant shoulder (pCIS), bone height change from placement, and bone overgrowth (for submerged implants).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>No significant differences were found between transgingival and submerged healing in any of the measured parameters, except for BATA on the buccal aspect in which significantly more bone formation was found for the transgingival healing group. For both groups, there was a gain in crestal bone height during the 12-week healing period.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Loaded compared with unloaded implants displayed comparable levels of osseointegration and equivalent marginal bone levels. This qualifies the implant placement protocol with respect to the osteotomy dimensions and subcrestal placement protocol for immediate loading.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>The here presented results related to osseointegration and crestal bone maintenance after submerged or transgingival healing have demonstrated a high level of consistency in the used in vivo translational model. The obtained results support the translation of the novel implant type in conjunction with the developed surgical workflow and placement protocol into further clinical investigation and use.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-021-03970-0","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T15:03:09Z","timestamp":1620226989000},"page":"6821-6832","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Peri-implant bone preservation of a novel, self-cutting, and fully tapered implant in the healed crestal ridge of minipigs: submerged vs. transgingival healing"],"prefix":"10.1007","volume":"25","author":[{"given":"Helena","family":"Francisco","sequence":"first","affiliation":[]},{"given":"Gary","family":"Finelle","sequence":"additional","affiliation":[]},{"given":"Fabien","family":"Bornert","sequence":"additional","affiliation":[]},{"given":"Rebecca","family":"Sandgren","sequence":"additional","affiliation":[]},{"given":"Valentin","family":"Herber","sequence":"additional","affiliation":[]},{"given":"Nils","family":"Warfving","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7990-5555","authenticated-orcid":false,"given":"Benjamin E.","family":"Pippenger","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,5,5]]},"reference":[{"key":"3970_CR1","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1111\/prd.12170","volume":"73","author":"D Buser","year":"2017","unstructured":"Buser D, Chappuis V, Belser UC, Chen S (2017) Implant placement post extraction in esthetic single tooth sites: when immediate, when early, when late? 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BEP declares that he is currently employed by Institut Straumann but does not declare any particular conflict of interest pertaining to this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This article contains data obtained from animals. All applicable international, national, and\/or institutional guidelines for the care and use of animals were followed and reporting followed the ARRIVE guidelines.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"For this type of study, formal consent is not required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}