{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T20:42:11Z","timestamp":1776199331354,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T00:00:00Z","timestamp":1617321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T00:00:00Z","timestamp":1617321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Odontology"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s10266-021-00603-6","type":"journal-article","created":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T18:02:21Z","timestamp":1617386541000},"page":"812-818","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Adjunctive procedure with solvent mixtures in non-surgical endodontic retreatment: does it affect root dentin hardness?"],"prefix":"10.1007","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9587-3557","authenticated-orcid":false,"given":"In\u00eas","family":"Ferreira","sequence":"first","affiliation":[]},{"given":"Ana Cristina","family":"Braga","sequence":"additional","affiliation":[]},{"given":"Maria Ascens\u00e3o","family":"Lopes","sequence":"additional","affiliation":[]},{"given":"Irene","family":"Pina-Vaz","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,4,2]]},"reference":[{"key":"603_CR1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1111\/j.1601-1546.2012.00279.x","volume":"22","author":"JF Siqueira","year":"2010","unstructured":"Siqueira JF, R\u00f4\u00e7as IN, Ricucci D. Biofilms in endodontic infection. Endod Top. 2010;22:33\u201349. https:\/\/doi.org\/10.1111\/j.1601-1546.2012.00279.x.","journal-title":"Endod Top"},{"key":"603_CR2","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1111\/j.1601-1546.2011.00254.x","volume":"19","author":"M Zehnder","year":"2008","unstructured":"Zehnder M, Paqu\u00e9 F. Disinfection of the root canal system during root canal re-treatment. Endod Topics. 2008;19:58\u201373. https:\/\/doi.org\/10.1111\/j.1601-1546.2011.00254.x.","journal-title":"Endod Topics"},{"key":"603_CR3","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1016\/j.joen.2009.07.015","volume":"35","author":"CM Takahashi","year":"2009","unstructured":"Takahashi CM, Cunha RS, de Martin AS, Fontana CE, Silveira CF, da Silveira Bueno CE. In vitro evaluation of the effectiveness of ProTaper universal rotary retreatment system for gutta-percha removal with or without a solvent. J Endod. 2009;35:1580\u20133. https:\/\/doi.org\/10.1016\/j.joen.2009.07.015.","journal-title":"J Endod"},{"key":"603_CR4","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1111\/iej.13047","volume":"52","author":"AF Campello","year":"2019","unstructured":"Campello AF, Almeida BM, Franzoni MA, Alves FRF, Marceliano-Alves MF, Rocas IN, Siqueira JF Jr, Provenzano JC. Influence of solvent and a supplementary step with a finishing instrument on filling material removal from canals connected by an isthmus. Int Endod J. 2019;52:716\u201324. https:\/\/doi.org\/10.1111\/iej.13047.","journal-title":"Int Endod J"},{"key":"603_CR5","doi-asserted-by":"publisher","first-page":"17","DOI":"10.22037\/iej.v16i1.29297","volume":"16","author":"I Ferreira","year":"2021","unstructured":"Ferreira I, Braga AC, Pina-Vaz I. Effect of gutta-percha solvents on the bond strength of sealers to intraradicular dentin: a systematic review. Iran Endod J. 2021;16:17\u201325. https:\/\/doi.org\/10.22037\/iej.v16i1.29297.","journal-title":"Iran Endod J"},{"key":"603_CR6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18081748","author":"P Neelakantan","year":"2017","unstructured":"Neelakantan P, Romero M, Vera J, Daood U, Khan AU, Yan A, Cheung GSP. Biofilms in endodontics-current status and future directions. Int J Mol Sci. 2017. https:\/\/doi.org\/10.3390\/ijms18081748.","journal-title":"Int J Mol Sci"},{"key":"603_CR7","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.joen.2010.12.008","volume":"37","author":"FR Alves","year":"2011","unstructured":"Alves FR, Almeida BM, Neves MA, Moreno JO, Rocas IN, Siqueira JF Jr. Disinfecting oval-shaped root canals: effectiveness of different supplementary approaches. J Endod. 2011;37:496\u2013501. https:\/\/doi.org\/10.1016\/j.joen.2010.12.008.","journal-title":"J Endod"},{"key":"603_CR8","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1016\/j.joen.2016.04.007","volume":"42","author":"FR Alves","year":"2016","unstructured":"Alves FR, Marceliano-Alves MF, Sousa JC, Silveira SB, Provenzano JC, Siqueira JF Jr. Removal of root canal fillings in curved canals using either reciprocating single- or rotary multi-instrument systems and a supplementary step with the xp-endo finisher. J Endod. 2016;42:1114\u20139. https:\/\/doi.org\/10.1016\/j.joen.2016.04.007.","journal-title":"J Endod"},{"key":"603_CR9","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1111\/iej.12991","volume":"52","author":"G De-Deus","year":"2019","unstructured":"De-Deus G, Belladonna FG, Zuolo AS, Sim\u00f5es-Carvalho M, Santos CB, Oliveira DS, Cavalcante DM, Silva EJNL. Effectiveness of reciproc blue in removing canal filling material and regaining apical patency. Int Endod J. 2019;52:250\u20137. https:\/\/doi.org\/10.1111\/iej.12991.","journal-title":"Int Endod J"},{"key":"603_CR10","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.joen.2016.10.040","volume":"43","author":"MP Martins","year":"2017","unstructured":"Martins MP, Duarte MAH, Cavenago BC, Kato AS, da Silveira Bueno CE. Effectiveness of the ProTaper next and reciproc systems in removing root canal filling material with sonic or ultrasonic irrigation: a micro-computed tomographic study. J Endod. 2017;43:467\u201371. https:\/\/doi.org\/10.1016\/j.joen.2016.10.040.","journal-title":"J Endod"},{"key":"603_CR11","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1111\/iej.12125","volume":"47","author":"RG Macedo","year":"2014","unstructured":"Macedo RG, Verhaagen B, Wesselink PR, Versluis M, van der Sluis LW. Influence of refreshment\/activation cycles and temperature rise on the reaction rate of sodium hypochlorite with bovine dentine during ultrasonic activated irrigation. Int Endod J. 2014;47:147\u201354. https:\/\/doi.org\/10.1111\/iej.12125.","journal-title":"Int Endod J"},{"key":"603_CR12","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1111\/iej.12788","volume":"51","author":"E Silva","year":"2018","unstructured":"Silva E, Belladonna FG, Zuolo AS, Rodrigues E, Ehrhardt IC, Souza EM, De-Deus G. Effectiveness of XP-endo finisher and XP-endo finisher R in removing root filling remnants: a micro-CT study. Int Endod J. 2018;51:86\u201391. https:\/\/doi.org\/10.1111\/iej.12788.","journal-title":"Int Endod J"},{"key":"603_CR13","doi-asserted-by":"publisher","first-page":"2465","DOI":"10.3390\/jcm9082465","volume":"9","author":"I Ferreira","year":"2020","unstructured":"Ferreira I, Babo PS, Braga AC, Gomes ME, Pina-Vaz I. Effect of sonic agitation of a binary mixture of solvents on filling remnants removal as an alternative to apical enlargement\u2014a micro-CT study. J Clin Med. 2020;9:2465. https:\/\/doi.org\/10.3390\/jcm9082465.","journal-title":"J Clin Med"},{"key":"603_CR14","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/j.1365-2591.2009.01627.x","volume":"43","author":"DR Violich","year":"2010","unstructured":"Violich DR, Chandler NP. The smear layer in endodontics\u2014a review. Int Endod J. 2010;43:2\u201315. https:\/\/doi.org\/10.1111\/j.1365-2591.2009.01627.x.","journal-title":"Int Endod J"},{"key":"603_CR15","doi-asserted-by":"publisher","first-page":"e39","DOI":"10.5395\/rde.2020.45.e39","volume":"45","author":"PP Rath","year":"2020","unstructured":"Rath PP, Yiu CKY, Matinlinna JP, Kishen A, Neelakantan P. The effect of root canal irrigants on dentin: a focused review. Restorat Dentistry Endodont. 2020;45:e39\u2013e39. https:\/\/doi.org\/10.5395\/rde.2020.45.e39.","journal-title":"Restorat Dentistry Endodont"},{"key":"603_CR16","doi-asserted-by":"publisher","first-page":"72","DOI":"10.4103\/endo.endo_28_18","volume":"31","author":"S Saha","year":"2019","unstructured":"Saha S, Singh R, Bhardwaj A, Vijaywargiya P, Billore J, Saxena D. Efficacy of smear layer removal by two Ayurvedic herbal irrigants, using continuous vs. syringe and needle irrigation. Endodontology. 2019;31:72\u20137. https:\/\/doi.org\/10.4103\/endo.endo_28_18.","journal-title":"Endodontology"},{"key":"603_CR17","doi-asserted-by":"publisher","first-page":"3237","DOI":"10.3390\/ma13143237","volume":"13","author":"I Ferreira","year":"2020","unstructured":"Ferreira I, Grenho L, Gomes P, Braga AC, Fernandes MH, Lopes MA, Pina-Vaz I. Efficacy and cytotoxicity of binary mixtures as root canal filling solvents. Materials. 2020;13:3237. https:\/\/doi.org\/10.3390\/ma13143237.","journal-title":"Materials"},{"key":"603_CR18","first-page":"25","volume":"12","author":"S Khedmat","year":"2015","unstructured":"Khedmat S, Hashemi A, Dibaji F, Kharrazifard MJ. Effect of chloroform, eucalyptol and orange oil solvents on the microhardness of human root dentin. J Dent (Tehran). 2015;12:25\u201330.","journal-title":"J Dent (Tehran)"},{"key":"603_CR19","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/s1079-2104(99)70225-8","volume":"87","author":"I Rotstein","year":"1999","unstructured":"Rotstein I, Cohenca N, Teperovich E, Moshonov J, Mor C, Roman I, Gedalia I. Effect of chloroform, xylene, and halothane on enamel and dentin microhardness of human teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;87:366\u20138. https:\/\/doi.org\/10.1016\/s1079-2104(99)70225-8.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"603_CR20","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1016\/j.joen.2011.06.005","volume":"37","author":"W Qian","year":"2011","unstructured":"Qian W, Shen Y, Haapasalo M. Quantitative analysis of the effect of irrigant solution sequences on dentin erosion. J Endod. 2011;37:1437\u201341. https:\/\/doi.org\/10.1016\/j.joen.2011.06.005.","journal-title":"J Endod"},{"key":"603_CR21","doi-asserted-by":"publisher","first-page":"792","DOI":"10.1097\/01.don.0000128747.89857.59","volume":"30","author":"H Ari","year":"2004","unstructured":"Ari H, Erdemir A, Belli S. Evaluation of the effect of endodontic irrigation solutions on the microhardness and the roughness of root canal dentin. J Endod. 2004;30:792\u20135. https:\/\/doi.org\/10.1097\/01.don.0000128747.89857.59.","journal-title":"J Endod"},{"key":"603_CR22","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1016\/j.joen.2010.04.002","volume":"36","author":"NV Ballal","year":"2010","unstructured":"Ballal NV, Mala K, Bhat KS. Evaluation of the effect of maleic acid and ethylenediaminetetraacetic acid on the microhardness and surface roughness of human root canal dentin. J Endod. 2010;36:1385\u20138. https:\/\/doi.org\/10.1016\/j.joen.2010.04.002.","journal-title":"J Endod"},{"key":"603_CR23","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1097\/01.don.0000136212.53475.ad","volume":"31","author":"AU Eldeniz","year":"2005","unstructured":"Eldeniz AU, Erdemir A, Belli S. Effect of EDTA and citric acid solutions on the microhardness and the roughness of human root canal dentin. J Endod. 2005;31:107\u201310. https:\/\/doi.org\/10.1097\/01.don.0000136212.53475.ad.","journal-title":"J Endod"},{"key":"603_CR24","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1097\/00004770-200201000-00004","volume":"28","author":"S Calt","year":"2002","unstructured":"Calt S, Serper A. Time-dependent effects of EDTA on dentin structures. J Endod. 2002;28:17\u20139. https:\/\/doi.org\/10.1097\/00004770-200201000-00004.","journal-title":"J Endod"},{"key":"603_CR25","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/0030-4220(94)90069-8","volume":"78","author":"R Garberoglio","year":"1994","unstructured":"Garberoglio R, Becce C. Smear layer removal by root canal irrigants. A comparative scanning electron microscopic study. Oral Surg Oral Med Oral Pathol. 1994;78:359\u201367. https:\/\/doi.org\/10.1016\/0030-4220(94)90069-8.","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"603_CR26","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.sdentj.2019.11.006","volume":"33","author":"I Ferreira","year":"2021","unstructured":"Ferreira I, Braga AC, Lopes MA, Pina-Vaz I. Improvement of the efficacy of endodontic solvents by ultrasonic agitation. Saudi Dent J. 2021;33:39\u201343. https:\/\/doi.org\/10.1016\/j.sdentj.2019.11.006.","journal-title":"Saudi Dent J"},{"key":"603_CR27","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1016\/j.joen.2017.03.015","volume":"43","author":"I Ferreira","year":"2017","unstructured":"Ferreira I, Soares S, Sousa J, Barros J, Braga AC, Lopes MA, Pina-Vaz I. New insight into the dissolution of epoxy resin-based sealers. J Endod. 2017;43:1505\u201310. https:\/\/doi.org\/10.1016\/j.joen.2017.03.015.","journal-title":"J Endod"},{"key":"603_CR28","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1016\/j.joen.2017.10.005","volume":"44","author":"A Kishen","year":"2018","unstructured":"Kishen A, Shrestha A, Del Carpio-Perochena A. Validation of biofilm assays to assess antibiofilm efficacy in instrumented root canals after syringe irrigation and sonic agitation. J Endod. 2018;44:292\u20138. https:\/\/doi.org\/10.1016\/j.joen.2017.10.005.","journal-title":"J Endod"},{"key":"603_CR29","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1089\/photob.2018.4529","volume":"37","author":"MB Akbulut","year":"2019","unstructured":"Akbulut MB, Terlemez A. Does the photon-induced photoacoustic streaming activation of irrigation solutions alter the dentin microhardness? Photobiomodul Photomed Laser Surg. 2019;37:38\u201344. https:\/\/doi.org\/10.1089\/photob.2018.4529.","journal-title":"Photobiomodul Photomed Laser Surg"},{"key":"603_CR30","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1744\/eej.2019.49369","volume":"4","author":"M Quteifani","year":"2019","unstructured":"Quteifani M, Madarati AA, Layous K, Tayyan MA. A comparative ex-vivo study of effects of different irrigation protocols with\/without laser activation on the root dentine\u2019s micro-hardness. Eur Endod J. 2019;4:127\u201332. https:\/\/doi.org\/10.1744\/eej.2019.49369.","journal-title":"Eur Endod J"},{"key":"603_CR31","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1111\/iej.13372","volume":"53","author":"\u00d6\u0130 Ulusoy","year":"2020","unstructured":"Ulusoy \u00d6\u0130, Mant\u0131 A\u015e, \u00c7elik B. Nanohardness reduction and root dentine erosion after final irrigation with ethylenediaminetetraacetic, etidronic and peracetic acids. Int Endod J. 2020;53:1549\u201358. https:\/\/doi.org\/10.1111\/iej.13372.","journal-title":"Int Endod J"},{"key":"603_CR32","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.actbio.2017.08.008","volume":"61","author":"LS Gu","year":"2017","unstructured":"Gu LS, Huang XQ, Griffin B, Bergeron BR, Pashley DH, Niu LN, Tay FR. Primum non nocere\u2014the effects of sodium hypochlorite on dentin as used in endodontics. Acta Biomater. 2017;61:144\u201356. https:\/\/doi.org\/10.1016\/j.actbio.2017.08.008.","journal-title":"Acta Biomater"},{"key":"603_CR33","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1601-1546.2012.00269.x","volume":"20","author":"L Tj\u00e4derhane","year":"2009","unstructured":"Tj\u00e4derhane L, Carrilho MR, Breschi L, Tay FR, Pashley DH. Dentin basic structure and composition\u2014an overview. Endod Top. 2009;20:3\u201329. https:\/\/doi.org\/10.1111\/j.1601-1546.2012.00269.x.","journal-title":"Endod Top"},{"key":"603_CR34","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1016\/j.joen.2005.08.007","volume":"32","author":"NM Grande","year":"2006","unstructured":"Grande NM, Plotino G, Falanga A, Pomponi M, Somma F. Interaction between EDTA and sodium hypochlorite: a nuclear magnetic resonance analysis. J Endod. 2006;32:460\u20134. https:\/\/doi.org\/10.1016\/j.joen.2005.08.007.","journal-title":"J Endod"},{"key":"603_CR35","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.dental.2010.01.009","volume":"26","author":"K Zhang","year":"2010","unstructured":"Zhang K, Tay FR, Kim YK, Mitchell JK, Kim JR, Carrilho M, Pashley DH, Ling JQ. The effect of initial irrigation with two different sodium hypochlorite concentrations on the erosion of instrumented radicular dentin. Dent Mater. 2010;26:514\u201323. https:\/\/doi.org\/10.1016\/j.dental.2010.01.009.","journal-title":"Dent Mater"},{"key":"603_CR36","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1016\/j.joen.2007.08.005","volume":"33","author":"M Marending","year":"2007","unstructured":"Marending M, Paqu\u00e9 F, Fischer J, Zehnder M. Impact of irrigant sequence on mechanical properties of human root dentin. J Endod. 2007;33:1325\u20138. https:\/\/doi.org\/10.1016\/j.joen.2007.08.005.","journal-title":"J Endod"},{"key":"603_CR37","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/s0109-5641(00)00021-x","volume":"16","author":"J Perdigao","year":"2000","unstructured":"Perdigao J, Lopes M, Geraldeli S, Lopes GC, Garcia-Godoy F. Effect of a sodium hypochlorite gel on dentin bonding. Dent Mater J. 2000;16:311\u201323. https:\/\/doi.org\/10.1016\/s0109-5641(00)00021-x.","journal-title":"Dent Mater J"},{"key":"603_CR38","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1023\/a:1013894432622","volume":"13","author":"CO Driscoll","year":"2002","unstructured":"Driscoll CO, Dowker SE, Anderson P, Wilson RM, Gulabivala K. Effects of sodium hypochlorite solution on root dentine composition. J Mater Sci Mater Med. 2002;13:219\u201323. https:\/\/doi.org\/10.1023\/a:1013894432622.","journal-title":"J Mater Sci Mater Med"},{"key":"603_CR39","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/s0099-2399(97)80171-9","volume":"23","author":"D Kaufman","year":"1997","unstructured":"Kaufman D, Mor C, Stabholz A, Rotstein I. Effect of gutta-percha solvents on calcium and phosphorus levels of cut human dentin. J Endod. 1997;23:614\u20135. https:\/\/doi.org\/10.1016\/s0099-2399(97)80171-9.","journal-title":"J Endod"},{"key":"603_CR40","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1039\/c4mb00548a","volume":"11","author":"SK Chaturvedi","year":"2015","unstructured":"Chaturvedi SK, Ahmad E, Khan JM, Alam P, Ishtikhar M, Khan RH. Elucidating the interaction of limonene with bovine serum albumin: a multi-technique approach. Mol Biosyst. 2015;11:307\u201316. https:\/\/doi.org\/10.1039\/c4mb00548a.","journal-title":"Mol Biosyst"},{"key":"603_CR41","first-page":"247","volume":"65","author":"RG Zgarian","year":"2017","unstructured":"Zgarian RG, Iacob F, Kaya DA, R\u0103u Ileana VG, Tihan GT. Effect of different essential oils on human dentine structure. Farmacia. 2017;65:247\u201351.","journal-title":"Farmacia"},{"key":"603_CR42","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1111\/iej.12522","volume":"49","author":"RA Bernardes","year":"2016","unstructured":"Bernardes RA, Duarte MAH, Vivan RR, Alcalde MP, Vasconcelos BC, Bramante CM. Comparison of three retreatment techniques with ultrasonic activation in flattened canals using micro-computed tomography and scanning electron microscopy. Int Endod J. 2016;49:890\u20137. https:\/\/doi.org\/10.1111\/iej.12522.","journal-title":"Int Endod J"},{"key":"603_CR43","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1007\/s00784-013-1086-0","volume":"18","author":"A Kele\u015f","year":"2014","unstructured":"Kele\u015f A, Alcin H, Kamalak A, Versiani MA. Oval-shaped canal retreatment with self-adjusting file: a micro-computed tomography study. Clin Oral Investig. 2014;18:1147\u201353. https:\/\/doi.org\/10.1007\/s00784-013-1086-0.","journal-title":"Clin Oral Investig"},{"key":"603_CR44","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1007\/s10103-013-1364-8","volume":"30","author":"H Arslan","year":"2015","unstructured":"Arslan H, Yeter KY, Karatas E, Yilmaz CB, Ayranci LB, Ozsu D. Effect of agitation of EDTA with 808-nm diode laser on dentin microhardness. Lasers Med Sci. 2015;30:599\u2013604. https:\/\/doi.org\/10.1007\/s10103-013-1364-8.","journal-title":"Lasers Med Sci"},{"key":"603_CR45","doi-asserted-by":"publisher","first-page":"e125","DOI":"10.1016\/j.tripleo.2007.04.019","volume":"104","author":"LD Oliveira","year":"2007","unstructured":"Oliveira LD, Carvalho CA, Nunes W, Valera MC, Camargo CH, Jorge AO. Effects of chlorhexidine and sodium hypochlorite on the microhardness of root canal dentin. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:e125-128. https:\/\/doi.org\/10.1016\/j.tripleo.2007.04.019.","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"603_CR46","doi-asserted-by":"publisher","first-page":"Zc53","DOI":"10.7860\/jcdr\/2016\/20819.8272","volume":"10","author":"B Gandhi","year":"2016","unstructured":"Gandhi B, Bollineni S, Janga RK, Saraswati D, Babu MR. Evaluating the effect of CPP-ACP as a final irrigant in improving the micro-hardness of erosive root dentin and its influence on the bond strength of self etch resin sealer\u2014an in-vitro study. J Clin Diagn Res. 2016;10:Zc53-56. https:\/\/doi.org\/10.7860\/jcdr\/2016\/20819.8272.","journal-title":"J Clin Diagn Res"},{"key":"603_CR47","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1016\/j.archoralbio.2015.10.002","volume":"60","author":"C Montoya","year":"2015","unstructured":"Montoya C, Arango-Santander S, Pel\u00e1ez-Vargas A, Arola D, Ossa EA. Effect of aging on the microstructure, hardness and chemical composition of dentin. Arch Oral Biol. 2015;60:1811\u201320. https:\/\/doi.org\/10.1016\/j.archoralbio.2015.10.002.","journal-title":"Arch Oral Biol"}],"container-title":["Odontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-021-00603-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10266-021-00603-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10266-021-00603-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,26]],"date-time":"2021-08-26T02:05:25Z","timestamp":1629943525000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10266-021-00603-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,2]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["603"],"URL":"https:\/\/doi.org\/10.1007\/s10266-021-00603-6","relation":{},"ISSN":["1618-1247","1618-1255"],"issn-type":[{"value":"1618-1247","type":"print"},{"value":"1618-1255","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,2]]},"assertion":[{"value":"5 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Study approval was obtained from the Ethics Committee of the Faculty of Dental Medicine of the University of Porto (n\u00ba3\/2018).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"For this type of study, formal consent is not required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}