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In a secondary analysis of a randomised controlled trial (RCT), 107 hospitalised patients (mean age 77.2 (SD 7.1) years, 56% female) underwent a comprehensive geriatric assessment (CGA). Assessments included the Multidimensional Prognostic Index (MPI), the Rosenberg Self-Esteem Scale (RSES), evaluation of geriatric syndromes and resources, the EQ-5D-5L quality-of-life scale, and the Geriatric Depression Scale (GDS). Follow-up data were collected via telephone six months later. After adjusting for age, sex, intervention, and MPI, baseline RSES were significantly associated with pressure ulcer risk (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.009), nutritional status (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.042), number of geriatric syndromes (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.003), geriatric resources (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), depressive symptoms (GDS,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), and quality of life (EQ-5D-5L,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.020). These findings show that self-esteem appears to be an independent mediator of multiple geriatric outcomes, including geriatric resources and syndromes, as well as of PROMs, beyond what is explained by MPI-based frailty. Incorporating self-esteem measures into CGA may enhance the identification of at-risk individuals and guide interventions.\n                  <\/jats:p>","DOI":"10.1007\/s10433-025-00888-4","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T03:05:19Z","timestamp":1761793519000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Self-esteem is associated with health status and PROMs in advanced age independent of multidimensional frailty: secondary analysis from a RCT with 6-month follow-up"],"prefix":"10.1007","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5562-262X","authenticated-orcid":false,"given":"Anna Maria","family":"Affeldt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"M\u00fcck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Ferring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Stegemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Wiebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Benzing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malte P.","family":"Bartram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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