{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:14:03Z","timestamp":1766067243006,"version":"3.37.3"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T00:00:00Z","timestamp":1609545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T00:00:00Z","timestamp":1609545600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/04750\/2020","SFRH\/BD\/112867\/2015"],"award-info":[{"award-number":["UIDB\/04750\/2020","SFRH\/BD\/112867\/2015"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["AIDS Behav"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s10461-020-03127-2","type":"journal-article","created":{"date-parts":[[2021,1,2]],"date-time":"2021-01-02T13:02:37Z","timestamp":1609592557000},"page":"1975-1983","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Provision of Preexposure Prophylaxis at the Portuguese National Health Service and Uptake in the Lisbon Cohort of Men Who Have Sex with Men"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9055-7491","authenticated-orcid":false,"given":"Paula","family":"Meireles","sequence":"first","affiliation":[]},{"given":"Francisco","family":"Fernandes","sequence":"additional","affiliation":[]},{"given":"Miguel","family":"Rocha","sequence":"additional","affiliation":[]},{"given":"Michael","family":"Plankey","sequence":"additional","affiliation":[]},{"given":"Henrique","family":"Barros","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,1,2]]},"reference":[{"issue":"23","key":"3127_CR1","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.1056\/NEJMoa1506273","volume":"373","author":"JM Molina","year":"2015","unstructured":"Molina JM, Capitant C, Spire B, ANRS IPERGAY Study Group, et al. On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. N Engl J Med. 2015;373(23):2237\u201346.","journal-title":"N Engl J Med."},{"issue":"10013","key":"3127_CR2","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0140-6736(15)00056-2","volume":"387","author":"S McCormack","year":"2016","unstructured":"McCormack S, Dunn DT, Desai M, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. Lancet. 2016;387(10013):53\u201360.","journal-title":"Lancet"},{"issue":"9","key":"3127_CR3","doi-asserted-by":"publisher","first-page":"e402","DOI":"10.1016\/S2352-3018(17)30089-9","volume":"4","author":"JM Molina","year":"2017","unstructured":"Molina JM, Charreau I, Spire B, ANRS IPERGAY Study Group, et al. Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study. Lancet HIV. 2017;4(9):e402\u201310.","journal-title":"Lancet HIV"},{"key":"3127_CR4","unstructured":"United States Food and Drug Administration. Truvada for PrEP fact sheet: ensuring safe and proper use. United States Food and Drug Administration. 2012. https:\/\/www.fda.gov\/media\/83586\/download. Accessed Feb 2020."},{"key":"3127_CR5","unstructured":"World Health Organization 2014 Policy brief: consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. World Health Organization https:\/\/www.who.int\/hiv\/pub\/toolkits\/keypopulations\/en\/. Accessed Feb 2020"},{"key":"3127_CR6","unstructured":"World Health Organization 2015 WHO expands recommendation on oral pre-exposure prophylaxis of HIV infection (PrEP): policy brief. World Health Organization https:\/\/www.who.int\/hiv\/pub\/prep\/policy-brief-prep-2015\/en. Accessed Feb 2020"},{"key":"3127_CR7","unstructured":"European Centre for Disease Prevention and Control 2015 Pre-exposure prophylaxis to prevent HIV among MSM in Europe. http:\/\/ecdc.europa.eu\/en\/activities\/sciadvice\/_layouts\/forms\/Review_DispForm.aspx?List=a3216f4c-f040-4f51-9f77-a96046dbfd72&ID=780#sthash.RVE9DaCE.dpuf. Accessed Feb 2020"},{"key":"3127_CR8","unstructured":"European Medicines Agency 2016 First medicine for HIV pre-exposure prophylaxis recommended for approval in the EU. http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Press_release\/2016\/07\/WC500210885.pdf. Accessed Feb 2020"},{"key":"3127_CR9","unstructured":"European Centre for Disease Prevention and Control (ECDC). Pre-exposure prophylaxis for HIV prevention in Europe and Central Asia. Monitoring implementation of the Dublin Declaration on partnership to fight HIV\/AIDS in Europe and Central Asia \u2013 2018\/19 progress report. Stockholm: ECDC; 2019."},{"key":"3127_CR10","unstructured":"Circular Normativa Conjunta n.\u00ba 01\/2018 do INFARMED\/ACSS\/DGS\/SPMS de 1 de mar\u00e7o de 2018, sobre o Programa de Acesso Precoce para Profilaxia de Pr\u00e9-exposi\u00e7\u00e3o da infe\u00e7\u00e3o por VIH-1 no Adulto. https:\/\/www.dgs.pt\/directrizes-da-dgs\/orientacoes-e-circulares-informativas\/circular-informativa-conjunta-n-012018infarmeddgs-pdf.aspx. Accessed Jan 2020"},{"key":"3127_CR11","unstructured":"Circular Normativa Conjunta n.\u00ba 02\/2018 do INFARMED\/ACSS\/DGS\/SPMS de 13 de mar\u00e7o de 2018, sobre o Programa de Acesso Precoce para Profilaxia de Pr\u00e9-exposi\u00e7\u00e3o da infe\u00e7\u00e3o por VIH-1 no Adulto. https:\/\/www.dgs.pt\/directrizes-da-dgs\/normas-e-circulares-normativas\/circular-normativa-conjunta-n-022018infarmedacssdgsspms-pdf.aspx. Accessed Jan 2020"},{"key":"3127_CR12","unstructured":"Portugal. Minist\u00e9rio da Sa\u00fade. Dire\u00e7\u00e3o-Geral da Sa\u00fade\/Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge. Infe\u00e7\u00e3o VIH e SIDA em Portugal - 2019. Lisboa: DGS\/INSA; 2019. http:\/\/www.insa.min-saude.pt\/wp-content\/uploads\/2019\/11\/RelatVIHSIDA2019.pdf. Accessed Dec 2019"},{"key":"3127_CR13","doi-asserted-by":"publisher","unstructured":"Meireles P, Rocha M, Campos MJ, Barros H. PrEP use in Portugal while waiting for a policy. Abstracts of the HIV Glasgow supplement. J Int AIDS Soc 2016;19(Suppl 7). https:\/\/doi.org\/10.7448\/IAS.19.8.21487. Available at: http:\/\/www.jiasociety.org\/index.php\/jias\/article\/view\/21487.","DOI":"10.7448\/IAS.19.8.21487"},{"issue":"6","key":"3127_CR14","doi-asserted-by":"publisher","first-page":"441","DOI":"10.20344\/amp.11474","volume":"32","author":"S Ribeiro","year":"2019","unstructured":"Ribeiro S, Rocha M. Pre-exposure prophylaxis counseling in a community sexual health clinic for men who have sex with men in Lisbon. Portugal Acta Med Port. 2019;32(6):441\u20137.","journal-title":"Portugal Acta Med Port."},{"issue":"3","key":"3127_CR15","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1136\/sextrans-2018-053705","volume":"95","author":"A Bourne","year":"2019","unstructured":"Bourne A, Alba B, Garner A, Spiteri G, Pharris A, Noori T. Use of, and likelihood of using, HIV pre-exposure prophylaxis among men who have sex with men in Europe and Central Asia: findings from a 2017 large geosocial networking application survey. Sex Transm Infect. 2019;95(3):187\u201392.","journal-title":"Sex Transm Infect."},{"key":"3127_CR16","unstructured":"The EMIS Network. EMIS-2017 \u2013 The European Men-Who-Have-Sex-With-Men Internet Survey. Key findings from 50 countries. Stockholm: European Centre for Disease Prevention and Control; 2019."},{"issue":"5","key":"3127_CR17","doi-asserted-by":"publisher","first-page":"e007220","DOI":"10.1136\/bmjopen-2014-007220","volume":"5","author":"P Meireles","year":"2015","unstructured":"Meireles P, Lucas R, Martins A, et al. The lisbon cohort of men who have sex with men. BMJ Open. 2015;5(5):e007220.","journal-title":"BMJ Open"},{"key":"3127_CR18","unstructured":"Lorente N, Folch C, Auss\u00f2 S, et al. European Community Health Worker Online Survey Report (D8.5). Edited by CEEISCAT, Barcelona, 2019. Publications Office of the European Union, Luxembourg, 2019."},{"key":"3127_CR19","unstructured":"Portugal. Minist\u00e9rio da Sa\u00fade. Dire\u00e7\u00e3o-Geral da Sa\u00fade. Norma n\u00ba 025\/2017 de 28\/11\/2017 atualizada a 16\/05\/2018. Available from https:\/\/www.dgs.pt\/directrizes-da-dgs\/normas-e-circulares-normativas\/norma-n-0252017-de-28112017-pdf.aspx. Accessed Mar 2019"},{"key":"3127_CR20","doi-asserted-by":"publisher","DOI":"10.1007\/s13178-019-00426-9","volume-title":"Eligibility for pre-exposure prophylaxis according to different guidelines in a cohort of HIV-negative men who have sex with men in lisbon","author":"P Meireles","year":"2020","unstructured":"Meireles P, Plankey M, Rocha M, et al. Eligibility for pre-exposure prophylaxis according to different guidelines in a cohort of HIV-negative men who have sex with men in lisbon. Portugal: Sex Res Social Policy; 2020."},{"issue":"41","key":"3127_CR21","doi-asserted-by":"publisher","first-page":"1900598","DOI":"10.2807\/1560-7917.ES.2019.24.41.1900598","volume":"24","author":"R Hayes","year":"2019","unstructured":"Hayes R, Schmidt AJ, Pharris A, et al. Estimating the \u2018PrEP gap\u2019: how implementation and access to PrEP differ between countries in Europe and Central Asia in 2019. Euro Surveill. 2019;24(41):1900598.","journal-title":"Euro Surveill."},{"issue":"17","key":"3127_CR22","doi-asserted-by":"publisher","first-page":"2633","DOI":"10.1097\/QAD.0000000000001983","volume":"32","author":"E Kamitani","year":"2018","unstructured":"Kamitani E, Wichser ME, Adegbite AH, et al. Increasing prevalence of self-reported HIV preexposure prophylaxis use in published surveys: a systematic review and meta-analysis. AIDS. 2018;32(17):2633\u20135.","journal-title":"AIDS"},{"issue":"2","key":"3127_CR23","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1097\/QAI.0000000000001791","volume":"79","author":"T Reyniers","year":"2018","unstructured":"Reyniers T, N\u00f6stlinger C, Laga M, et al. Choosing between daily and event-driven pre-exposure prophylaxis: results of a Belgian PrEP demonstration project. J Acquir Immune Defic Syndr. 2018;79(2):186\u201394.","journal-title":"J Acquir Immune Defic Syndr."},{"issue":"3","key":"3127_CR24","doi-asserted-by":"publisher","first-page":"e25105","DOI":"10.1002\/jia2.25105","volume":"21","author":"E Hoornenborg","year":"2018","unstructured":"Hoornenborg E, Achterbergh RC, van der Loeff MFS, et al. Men who have sex with men more often chose daily than event-driven use of pre-exposure prophylaxis: baseline analysis of a demonstration study in Amsterdam. J Int AIDS Soc. 2018;21(3):e25105.","journal-title":"J Int AIDS Soc."},{"issue":"sup2","key":"3127_CR25","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1080\/09540121.2018.1468014","volume":"30","author":"I Rivierez","year":"2018","unstructured":"Rivierez I, Quatremere G, Spire B, Ghosn J, Rojas CD. Lessons learned from the experiences of informal PrEP users in France: results from the ANRS-PrEPage study. AIDS Care. 2018;30(sup2):48\u201353.","journal-title":"AIDS Care"},{"issue":"1","key":"3127_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/hiv.12528","volume":"19","author":"X Wang","year":"2018","unstructured":"Wang X, Nwokolo N, Korologou-Linden R, et al. InterPrEP: internet-based pre-exposure prophylaxis with generic tenofovir disoproxil fumarate\/emtricitabine in London: analysis of pharmacokinetics, safety and outcomes. HIV Med. 2018;19(1):1\u20136.","journal-title":"HIV Med."},{"issue":"10","key":"3127_CR27","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1080\/17441692.2017.1373139","volume":"13","author":"J Brisson","year":"2018","unstructured":"Brisson J. Ethical public health issues for the use of informal PrEP. Glob Public Health. 2018;13(10):1382\u20137.","journal-title":"Glob Public Health"},{"issue":"25","key":"3127_CR28","doi-asserted-by":"publisher","first-page":"30263","DOI":"10.2807\/1560-7917.ES.2016.21.25.30263","volume":"21","author":"T Noori","year":"2016","unstructured":"Noori T, Pharris A. Meeting report: pre-exposure human immunodeficiency virus prophylaxis in the EU\/EEA: challenges and opportunities, stockholm April 2016. Euro Surveill. 2016;21(25):30263.","journal-title":"Euro Surveill."},{"issue":"6","key":"3127_CR29","doi-asserted-by":"crossref","first-page":"e25350","DOI":"10.1002\/jia2.25350","volume":"22","author":"D Rojas Castro","year":"2019","unstructured":"Rojas Castro D, Delabre RM, Morel S, Michels D, Spire B. Community engagement in the provision of culturally competent HIV and STI prevention services: lessons from the French experience in the era of PrEP. J Int AIDS Soc. 2019;22(6):e25350.","journal-title":"J Int AIDS Soc."},{"issue":"4","key":"3127_CR30","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1111\/hiv.12419","volume":"18","author":"D Rojas Castro","year":"2017","unstructured":"Rojas Castro D, Quatremere G, Sagaon-Teyssier L, et al. Informal pre-exposure prophylaxis use in France: results from the flash PrEP survey (2014). HIV Med. 2017;18(4):308\u201310.","journal-title":"HIV Med."},{"issue":"5","key":"3127_CR31","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1093\/her\/cyr064","volume":"26","author":"T Lorenc","year":"2011","unstructured":"Lorenc T, Marrero-Guillam\u00f3n I, Llewellyn A, et al. HIV testing among men who have sex with men (MSM): systematic review of qualitative evidence. Health Educ Res. 2011;26(5):834\u201346.","journal-title":"Health Educ Res."},{"key":"3127_CR32","unstructured":"World Health Organization\/Joint United Nations Programme on HIV\/AIDS. Second generation surveillance for HIV: the next decade. http:\/\/www.who.int\/reproductivehealth\/publications\/rtis\/CDS_CSR_EDC_2000_5\/en\/. Accessed Feb 2020"},{"issue":"suppl 2","key":"3127_CR33","doi-asserted-by":"publisher","first-page":"S67","DOI":"10.1097\/01.aids.0000172879.20628.e1","volume":"19","author":"R Magnani","year":"2005","unstructured":"Magnani R, Sabin K, Saidel T, Heckathorn D. Review of sampling hard-to-reach and hidden populations for HIV surveillance. AIDS. 2005;19(suppl 2):S67\u201372.","journal-title":"AIDS"},{"issue":"6","key":"3127_CR34","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1007\/s10461-010-9743-7","volume":"14","author":"D Paquette","year":"2010","unstructured":"Paquette D, De Wit J. Sampling methods used in developed countries for behavioural surveillance among men who have sex with men. AIDS Behav. 2010;14(6):1252\u201364.","journal-title":"AIDS Behav."},{"key":"3127_CR35","unstructured":"World Health Organization\/Joint United Nations Programme on HIV\/AIDS 2011 Guidelines on surveillance among populations most at risk for HIV. http:\/\/www.unaids.org\/en\/media\/unaids\/contentassets\/documents\/epidemiology\/2011\/20110518_Surveillance_among_most_at_risk.pdf. Accessed Feb 2020"}],"container-title":["AIDS and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10461-020-03127-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10461-020-03127-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10461-020-03127-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T17:51:11Z","timestamp":1697478671000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10461-020-03127-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,2]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["3127"],"URL":"https:\/\/doi.org\/10.1007\/s10461-020-03127-2","relation":{},"ISSN":["1090-7165","1573-3254"],"issn-type":[{"type":"print","value":"1090-7165"},{"type":"electronic","value":"1573-3254"}],"subject":[],"published":{"date-parts":[[2021,1,2]]},"assertion":[{"value":"7 December 2020","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2021","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Ethics Committee for Health of S\u00e3o Jo\u00e3o Hospital Center and Medical School, University of Porto, in 2012 (ID 104\/12). Later, two extension requests for data collection were submitted and approved (April 2013 and March 2018). The data treatment authorization from the Portuguese Data Protection Authority was received in 2013 (Authorization Number 3897\/2013). The 1964 Helsinki Declaration and its later amendments or comparable ethical standards are being followed. Those accepting to participate are asked to sign the informed consent, at each visit, and given a duplicate of the document.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}