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The microspheres were evaluated in terms of size, shape, thermal stability, encapsulation efficiency, and eugenol kinetics release. CA-based microspheres proved to be the best, thus being selected for subsequent experiments. Comparable properties of the CA-based microspheres were achieved ongoing from 100\u00a0mL to higher batch volumes (up to 2000\u00a0mL). The eugenol-loaded microspheres were successfully incorporated into cotton fabrics using a padding technique, confirmed by FE-SEM. Eugenol release profiles from the impregnated textiles demonstrated a slow and controlled release (less than 20% of the encapsulated amount over 90\u00a0days). The developed microspheres demonstrated to be\u00a0the most promising for the retention and protection of hydrophobic active compounds for possible textile applications.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Graphic abstract<\/jats:title>\n\n<\/jats:sec>","DOI":"10.1007\/s10570-020-03010-2","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T14:03:58Z","timestamp":1581343438000},"page":"4109-4121","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Eugenol-loaded microspheres incorporated into textile substrates"],"prefix":"10.1007","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3465-8217","authenticated-orcid":false,"given":"M. G.","family":"Sim\u00f5es","sequence":"first","affiliation":[]},{"given":"P.","family":"Coimbra","sequence":"additional","affiliation":[]},{"given":"A. 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