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Also, the authors have no relevant financial or non-financial interests to disclose. Jos\u00e9 Manuel Gonz\u00e1lez M\u00e9ijome has a proprietary interest in the LDA device. Other authors declare that they do not have any proprietary or financial interest in any of the materials mentioned in this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Following the Declaration of Helsinki (World Medical Declaration of Helsinki, 2001), all patients were informed and carry out about the purpose of the study and all methods. All the subjects had the opportunity to clarify their doubts and sign an informed consent form before being enrolled in the study. So, the informed consent was obtained for all the participants. 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