{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:59:13Z","timestamp":1761101953639},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,1,25]],"date-time":"2011-01-25T00:00:00Z","timestamp":1295913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Genetic Counseling"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Predictive testing protocols are intended to help patients affected with hereditary conditions understand their condition and make informed reproductive choices. However, predictive protocols may expose clinicians and patients to ethical dilemmas that interfere with genetic counseling and the decision making process. This paper describes ethical dilemmas in a series of five cases involving predictive testing for hereditary ataxias in Cuba. The examples herein present evidence of the deeply controversial situations faced by both individuals at risk and professionals in charge of these predictive studies, suggesting a need for expanded guidelines to address such complexities.<\/jats:p>","DOI":"10.1007\/s10897-010-9347-4","type":"journal-article","created":{"date-parts":[[2011,1,24]],"date-time":"2011-01-24T16:26:31Z","timestamp":1295886391000},"page":"241-248","source":"Crossref","is-referenced-by-count":8,"title":["Ethical Dilemmas in Genetic Testing: Examples from the Cuban Program for Predictive Diagnosis of Hereditary Ataxias"],"prefix":"10.1002","volume":"20","author":[{"given":"Tania Cruz","family":"Mari\u00f1o","sequence":"first","affiliation":[{"name":"Predictive Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"},{"name":"Avenida Cajigal No 525 F2 Entre Luz y Progreso. Reparto Luz Holgu\u00edn CP 80 100 Cuba"}]},{"given":"Rub\u00e9n Reynaldo","family":"Armi\u00f1\u00e1n","sequence":"additional","affiliation":[{"name":"Predictive Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Humberto Jorge","family":"Cede\u00f1o","sequence":"additional","affiliation":[{"name":"Predictive Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Jos\u00e9 Miguel Laffita","family":"Mesa","sequence":"additional","affiliation":[{"name":"Molecular Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Yanetza Gonz\u00e1lez","family":"Zaldivar","sequence":"additional","affiliation":[{"name":"Molecular Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Ra\u00fal Aguilera","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Predictive Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Miguel Vel\u00e1zquez","family":"Santos","sequence":"additional","affiliation":[{"name":"Predictive Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Luis Enrique Almaguer","family":"Mederos","sequence":"additional","affiliation":[{"name":"Molecular Genetics Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"}]},{"given":"Milena Paneque","family":"Herrera","sequence":"additional","affiliation":[{"name":"Centre for Predictive and Preventive Genetics (CGPP) IBMC, University of Porto Porto Portugal"}]},{"given":"Luis Vel\u00e1zquez","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Neurophysiology Department Center for Research and Rehabilitation of Hereditary Ataxias (CIRAH) Holgu\u00edn Cuba"},{"name":"Avenida Cajigal No 525 F2 Entre Luz y Progreso. 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