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As a cross-sectional study within the CLaSP study, 509 people with Parkinson\u2019s disease completed the \u201cSchedule-for-Meaning-in-Life-Evaluation\u201d (SMiLE) questionnaire. We compared the results to those of a representative sample of healthy participants (<jats:italic>n<\/jats:italic>\u2009=\u2009856). People with late-stage Parkinson\u2019s disease reported family, partnership and spirituality as the greatest areas of importance. Overall, they had lower SMiLE indices compared to healthy participants. People with late-stage Parkinson\u2019s disease rated the importance of core meaning in life areas (namely family, social relations and health) as significantly lower than the representative cohort and they also rated satisfaction as significantly lower in most areas. In conclusion, people with late-stage Parkinson\u2019s disease do have areas where they can find meaning, such as family, partnership and spirituality. However, they indicate a lack of fulfilment of their individual MiL, reflected by low satisfaction rates in the majority of meaning in life categories. The need for spiritual support for people with Parkinson\u2019s disease indicates the important role of chaplains to help people with Parkinson\u2019s disease maintain meaning in life.<\/jats:p>","DOI":"10.1007\/s10943-023-01962-w","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T04:22:58Z","timestamp":1701750178000},"page":"2140-2154","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Meaning in Life in Late-Stage Parkinson\u2019s Disease: Results from the Care of Late-Stage Parkinsonism Study (CLaSP) in Six European Countries"],"prefix":"10.1007","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3258-543X","authenticated-orcid":false,"given":"Sarah K.","family":"Bublitz","sequence":"first","affiliation":[]},{"given":"Cornelia","family":"Brandst\u00f6tter","sequence":"additional","affiliation":[]},{"given":"Martin","family":"Fegg","sequence":"additional","affiliation":[]},{"given":"Joaquim J.","family":"Ferreira","sequence":"additional","affiliation":[]},{"given":"Per","family":"Odin","sequence":"additional","affiliation":[]},{"given":"Bastiaan R.","family":"Bloem","sequence":"additional","affiliation":[]},{"given":"Wassilios G.","family":"Meissner","sequence":"additional","affiliation":[]},{"given":"Richard","family":"Dodel","sequence":"additional","affiliation":[]},{"given":"Anette","family":"Schrag","sequence":"additional","affiliation":[]},{"given":"Stefan","family":"Lorenzl","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2023,12,5]]},"reference":[{"issue":"10","key":"1962_CR1","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1002\/(SICI)1099-1166(199910)14:10<866::AID-GPS38>3.0.CO;2-Z","volume":"14","author":"D Aarsland","year":"1999","unstructured":"Aarsland, D., Larsen, J. 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J.J.F. has held consultancy functions with Abbvie, BIAL, NeuroDerm, Zambon, Sunovion, Affiris, and ONO Pharmaceutical Co., Ltd; has received lecture fees from BIAL, Sunovion, ONO, Zambon, and Abbvie; and has received grants from Novartis, Funda\u00e7ao Merck Sharp & Dohme (MSD, Portugal), and Medtronic. P.O. has received honoraria for lectures and expert advice from AbbVie, BIAL, Britannia, Global Kinetics, Lobsor, Nordic Infucare, PD Neurotechnology, and Zambon. B.R.B. has received honoraria from serving on the scientific advisory board for Zambon, Biogen, UCB, and Walk with Path; has received fees for speaking at conferences from AbbVie, Zambon, Roche, GE Healthcare, and BIAL; and has received research support from the Netherlands Organization for Scientific Research, The Michael J. Fox Foundation, UCB, Abbie, Zambon, the Stichting Parkinson Fonds, the Hersenstichting Nederland, the Parkinson\u2019s Foundation, Verily Life Sciences, Horizon 2020, the Topsector Life Sciences and Health, and the Parkinson Vereniging. W.G.M. has received fees for editorial activities with Elsevier, and\u00a0has served as advisor for Lundbeck, Biohaven, Takeda, Servier, Roche, Alterity, Inhibikase, and TEVA.\u00a0R.D. has no additional disclosures to report. A.S. was supported by research funding or support from University College London, National Institute of Health, National Institute for Health Research University College London Hospital (ULCH) Biomedical Research Centre, the International Parkinson and Movement Disorder Society, the European Commission, Parkinson\u2019s UK, GE Healthcare, and the Economic and Social Research Council; honoraria for consultancies from Abbvie\u00a0and\u00a0BIAL. S.L. has received honoraria for lectures from UCB and AbbVie.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}