{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:22:39Z","timestamp":1760984559193},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,8,10]],"date-time":"2012-08-10T00:00:00Z","timestamp":1344556800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharm Res"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1007\/s11095-012-0851-0","type":"journal-article","created":{"date-parts":[[2012,8,9]],"date-time":"2012-08-09T19:03:51Z","timestamp":1344539031000},"page":"81-89","source":"Crossref","is-referenced-by-count":20,"title":["Solid-Solid Transformation in Racemic Ibuprofen"],"prefix":"10.1007","volume":"30","author":[{"given":"Emeline","family":"Dudognon","sequence":"first","affiliation":[]},{"given":"Nat\u00e1lia T.","family":"Correia","sequence":"additional","affiliation":[]},{"given":"Florence","family":"Dan\u00e8de","sequence":"additional","affiliation":[]},{"given":"Marc","family":"Descamps","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2012,8,10]]},"reference":[{"key":"851_CR1","volume-title":"Polymorphism in pharmaceutical solids. Drugs and the pharmaceutical sciences vol. 95","author":"HG Brittain","year":"1999","unstructured":"Brittain HG. Polymorphism in pharmaceutical solids. Drugs and the pharmaceutical sciences vol. 95. New York: Marcel Dekker; 1999."},{"key":"851_CR2","volume-title":"Polymorphism in molecular crystals","author":"J Bernstein","year":"2002","unstructured":"Bernstein J. Polymorphism in molecular crystals. Oxford: Oxford Science; 2002."},{"key":"851_CR3","doi-asserted-by":"crossref","DOI":"10.1002\/3527607889","volume-title":"Polymorphism in the pharmaceutical industry","author":"R Hilfiker","year":"2006","unstructured":"Hilfiker R. Polymorphism in the pharmaceutical industry. Weiheim: Wiley-VCH; 2006."},{"key":"851_CR4","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.tca.2003.08.021","volume":"412","author":"F Xu","year":"2004","unstructured":"Xu F, Sun LX, Tan ZC, Liang JG, Li RL. Thermodynamic study of ibuprofen by adiabatic calorimetry and thermal analysis. Thermochim Acta. 2004;412:33\u20137.","journal-title":"Thermochim Acta"},{"key":"851_CR5","first-page":"73","volume":"3","author":"JF McConnell","year":"1974","unstructured":"McConnell JF. 2-(4-isobuthylphenyl) propionic acid. C13 H18 O2 ibuprofen or prufen. Cryst Struct Comm. 1974;3:73\u20135.","journal-title":"Cryst Struct Comm"},{"key":"851_CR6","first-page":"951","volume":"C53","author":"N Shankland","year":"1997","unstructured":"Shankland N, Wilson CC, Florence AJ, Cox PJ. Refinement of ibuprofen at 100\u00a0K by single-crystal pulsed neutron diffraction. Acta Crystallogr. 1997;C53:951\u20134.","journal-title":"Acta Crystallogr"},{"key":"851_CR7","doi-asserted-by":"crossref","first-page":"11087","DOI":"10.1021\/jp8040428","volume":"112","author":"AR Br\u00e1s","year":"2008","unstructured":"Br\u00e1s AR, Noronha JP, Antunes AMM, Cardoso MM, Sch\u00f6nhals A, Affouard F, Dionisio M, Correia NT. Molecular motions in amorphous ibuprofen as studied by broadband dielectric spectroscopy. J Phys Chem B. 2008;112:11087\u201399.","journal-title":"J Phys Chem B"},{"key":"851_CR8","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1002\/jps.20921","volume":"96","author":"GP Johari","year":"2007","unstructured":"Johari GP, Kim S, Shanker RM. Dielectric relaxation and crystallization of ultraviscous melt and glassy states of aspirin, ibuprofen, progesterone, and quinidine. J Pharm Sci. 2007;96:1159\u201375.","journal-title":"J Pharm Sci"},{"issue":"12","key":"851_CR9","doi-asserted-by":"crossref","first-page":"2853","DOI":"10.1007\/s11095-008-9655-7","volume":"25","author":"E Dudognon","year":"2008","unstructured":"Dudognon E, Dan\u00e8de F, Descamps M, Correia NT. Evidence for a new crystalline phase of racemic ibuprofen. Pharm Res. 2008;25(12):2853\u20138.","journal-title":"Pharm Res"},{"key":"851_CR10","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1107\/S0108768109047363","volume":"B66","author":"P Derollez","year":"2010","unstructured":"Derollez P, Dudognon E, Affouard F, Dan\u00e8de F, Correia NT, Descamps M. Ab initio structure determination of phase II of racemic ibuprofen by X-ray powder diffraction. Acta Crystallogr. 2010;B66:76\u201380.","journal-title":"Acta Crystallogr"},{"key":"851_CR11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0040-6031(97)00271-2","volume":"307","author":"V Legrand","year":"1997","unstructured":"Legrand V, Descamps M, Alba-Simionesco C. Glass-forming meta-toluidine: a thermal and structural analysis of its crystalline polymorphism and devitrification. Thermochim Acta. 1997;307:77\u201383.","journal-title":"Thermochim Acta"},{"key":"851_CR12","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1088\/0953-8984\/15\/23\/306","volume":"15","author":"F Paladi","year":"2003","unstructured":"Paladi F, Oguni M. Generation and extinction of crystal nuclei in an extremely non-equilibrium glassy state of salol. J Phys Condens Matter. 2003;15:3909\u201317.","journal-title":"J Phys Condens Matter"},{"key":"851_CR13","doi-asserted-by":"crossref","first-page":"144202","DOI":"10.1103\/PhysRevB.65.144202","volume":"65","author":"F Paladi","year":"2002","unstructured":"Paladi F, Oguni M. Anomalous generation and extinction of crystal nuclei in nonequilibrium supercooled liquid o-benzylphenol. Phys Rev B. 2002;65:144202.","journal-title":"Phys Rev B"},{"key":"851_CR14","doi-asserted-by":"crossref","unstructured":"Burger A, Ramberger R. On the polymorphism of pharmaceuticals and other molecular crystals. I. Theory of thermodynamic rules. Mikrochimica Acta II. 1979:259\u2013271.","DOI":"10.1007\/BF01197379"},{"key":"851_CR15","doi-asserted-by":"crossref","unstructured":"Burger A, Ramberger R. On the polymorphism of pharmaceuticals and other molecular crystals. II. Applicability of thermodynamic rules. Mikrochimica Acta II. 1979:273\u2013316.","DOI":"10.1007\/BF01197380"},{"key":"851_CR16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1515\/zpch-1897-2233","volume":"22","author":"W Ostwald","year":"1897","unstructured":"Ostwald W. Studien \u00fcber die Bildung und Umwandlung fester K\u00f6rper. 1. Abhandlung: \u00dcbers\u00e4ttigung und \u00dcberkaltung. Z Phys Chem. 1897;22:289\u2013330.","journal-title":"Z Phys Chem"},{"key":"851_CR17","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1021\/op030026l","volume":"7","author":"T Threlfall","year":"2003","unstructured":"Threlfall T. Structural and thermodynamic explanations of Ostwald\u2019s rule. Org Process Res Dev. 2003;7:1017\u201327.","journal-title":"Org Process Res Dev"},{"key":"851_CR18","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0022-3697(65)90120-4","volume":"26","author":"AI Kitaigorodskiy","year":"1965","unstructured":"Kitaigorodskiy AI, Mnyukh YV, Asadov YG. Relationships for single crystal growth during polymorphic transformation. J Phys Chem Solids. 1965;26:463\u201372.","journal-title":"J Phys Chem Solids"},{"key":"851_CR19","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1063\/1.1750380","volume":"7","author":"M Avrami","year":"1939","unstructured":"Avrami M. Kinetics of phase change. I* general theory. J Chem Phys. 1939;7:1103\u201312.","journal-title":"J Chem Phys"},{"key":"851_CR20","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1063\/1.1750631","volume":"8","author":"M Avrami","year":"1940","unstructured":"Avrami M. Kinetics of phase change. II transformation-time relations for random distribution of nuclei. J Chem Phys. 1940;8:212\u201324.","journal-title":"J Chem Phys"},{"key":"851_CR21","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1063\/1.1750872","volume":"9","author":"M Avrami","year":"1941","unstructured":"Avrami M. Granulation, phase change, and microstructure kinetics of phase change. III*. J Chem Phys. 1941;9:177\u201384.","journal-title":"J Chem Phys"},{"issue":"4","key":"851_CR22","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0022-3697(92)90096-V","volume":"53","author":"E Woldt","year":"1992","unstructured":"Woldt E. The relationship between isothermal and non-isothermal description of Johnson-Mehl-Avrami-Kolmogorov kinetics. J Phys Chem Solids. 1992;53(4):521\u20137.","journal-title":"J Phys Chem Solids"}],"container-title":["Pharmaceutical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11095-012-0851-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11095-012-0851-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11095-012-0851-0","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T05:54:26Z","timestamp":1559368466000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11095-012-0851-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,10]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["851"],"URL":"https:\/\/doi.org\/10.1007\/s11095-012-0851-0","relation":{},"ISSN":["0724-8741","1573-904X"],"issn-type":[{"value":"0724-8741","type":"print"},{"value":"1573-904X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,10]]}}}