{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T15:29:38Z","timestamp":1774279778953,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2014,9,24]],"date-time":"2014-09-24T00:00:00Z","timestamp":1411516800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Med Biol Eng Comput"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1007\/s11517-014-1197-z","type":"journal-article","created":{"date-parts":[[2014,9,23]],"date-time":"2014-09-23T19:07:15Z","timestamp":1411499235000},"page":"971-983","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Toward hemodynamic diagnosis of carotid artery stenosis based on ultrasound image data and computational modeling"],"prefix":"10.1007","volume":"52","author":[{"given":"Lu\u00edsa C.","family":"Sousa","sequence":"first","affiliation":[]},{"given":"Catarina F.","family":"Castro","sequence":"additional","affiliation":[]},{"given":"Carlos C.","family":"Ant\u00f3nio","sequence":"additional","affiliation":[]},{"given":"Andr\u00e9 Miguel F.","family":"Santos","sequence":"additional","affiliation":[]},{"given":"Rosa Maria","family":"dos Santos","sequence":"additional","affiliation":[]},{"given":"Pedro Miguel A. C.","family":"Castro","sequence":"additional","affiliation":[]},{"given":"Elsa","family":"Azevedo","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o Manuel R. S.","family":"Tavares","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2014,9,24]]},"reference":[{"issue":"1","key":"1197_CR1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jvs.2010.07.045","volume":"53","author":"AF AbuRahma","year":"2011","unstructured":"AbuRahma AF, Srivastava M, Stone PA, Mousa AY, Jain A, Dean LS, Keiffer T, Emmett M (2011) Critical appraisal of the Carotid Duplex Consensus criteria in the diagnosis of carotid artery stenosis. J Vasc Surg 53(1):53\u201359","journal-title":"J Vasc Surg"},{"issue":"3\u20134","key":"1197_CR2","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0045-7825(99)00200-5","volume":"182","author":"R Almeida","year":"2000","unstructured":"Almeida R, Feij\u00f3o R, Gale\u00e3o A, Padra C, Silva R (2000) Adaptive finite element computational fluid dynamics using an anisotropic error estimator. Comput Methods Appl Mech Eng 182(3\u20134):379\u2013400","journal-title":"Comput Methods Appl Mech Eng"},{"key":"1197_CR3","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1007\/s11517-008-0420-1","volume":"46","author":"L Antiga","year":"2008","unstructured":"Antiga L, Piccinelli M, Botti L, Ene-Iordache B, Remuzzi A, Steinman D (2008) An image-based modeling framework for patient-specific computational hemodynamics. Med Biol Eng Comput 46:1097\u20131112","journal-title":"Med Biol Eng Comput"},{"key":"1197_CR4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0021-9290(99)00164-5","volume":"33","author":"R Botnar","year":"2000","unstructured":"Botnar R, Rappitsch G, Scheidegger MB, Liepsch D, Perktold K, Boesiger P (2000) Hemodynamics in the carotid artery bifurcation: a comparison between numerical simulations and in vitro MRI measurements. J Biomech 33:137\u2013144","journal-title":"J Biomech"},{"issue":"2","key":"1197_CR5","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1109\/83.902291","volume":"10","author":"TF Chan","year":"2001","unstructured":"Chan TF, Vese LA (2001) Active contours without edges. IEEE Trans Image Process 10(2):266\u2013277","journal-title":"IEEE Trans Image Process"},{"issue":"1","key":"1197_CR6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/ncpcardio1397","volume":"6","author":"PF Davies","year":"2009","unstructured":"Davies PF (2009) Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovascu Med 6(1):16\u201326","journal-title":"Nat Clin Pract Cardiovascu Med"},{"issue":"4","key":"1197_CR7","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s11517-010-0583-4","volume":"48","author":"G Santis De","year":"2010","unstructured":"De Santis G, Mortier P, De Beule M, Segers P, Verdonck P, Verhegghe B (2010) Patient-specific computational fluid dynamics: structured mesh generation from coronary angiography. Med Biol Eng Comput 48(4):371\u2013380","journal-title":"Med Biol Eng Comput"},{"issue":"6","key":"1197_CR8","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1080\/10255842.2011.629997","volume":"16","author":"G Santis De","year":"2013","unstructured":"De Santis G, Conti M, Trachet B, De Schryver T, De Beule M, Degroote J, Vierendeels J, Auricchio F, Segers P, Verdonck P, Verhegghe B (2013) Haemodynamic impact of stent-vessel (mal) apposition following carotid artery stenting: mind the gaps! Comput Methods Biomech Biomed Engin 16(6):648\u2013659","journal-title":"Comput Methods Biomech Biomed Engin"},{"issue":"4","key":"1197_CR9","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/cnm.2529","volume":"29","author":"J Dong","year":"2013","unstructured":"Dong J, Wong KK, Tu J (2013) Hemodynamics analysis of patient-specific carotid bifurcation: a CFD model of downstream peripheral vascular impedance. Int J Numer Method Biomed Eng 29(4):476\u2013491","journal-title":"Int J Numer Method Biomed Eng"},{"issue":"2","key":"1197_CR10","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s10409-009-0227-9","volume":"25","author":"Y Fan","year":"2009","unstructured":"Fan Y, Jiang W, Zou Y, Li J, Chen J, Deng X (2009) Numerical simulation of pulsatile non-Newtonian flow in the carotid artery bifurcation. Acta Mech Sin 25(2):249\u2013255","journal-title":"Acta Mech Sin"},{"issue":"6","key":"1197_CR11","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s11517-012-1031-4","volume":"51","author":"N Filipovic","year":"2013","unstructured":"Filipovic N, Teng Z, Radovic M, Saveljic I, Fotiadis D, Parodi O (2013) Computer simulation of three-dimensional plaque formation and progression in the carotid artery. Med Biol Eng Comput 51(6):607\u2013616","journal-title":"Med Biol Eng Comput"},{"key":"1197_CR12","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1118\/1.599014","volume":"27","author":"JD Gill","year":"2000","unstructured":"Gill JD, Ladak HM, Steinman DA, Fenster A (2000) Accuracy and variability assessment of a semiautomatic technique for segmentation of the carotid arteries from three dimensional ultrasound images. Med Phys 27:1333\u20131342","journal-title":"Med Phys"},{"key":"1197_CR13","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1161\/STROKEAHA.107.484766","volume":"38","author":"HC Groen","year":"2007","unstructured":"Groen HC, Gijsen FJH, van der Lugt A, Ferguson MS, Hatsukami TS, van der Steen AFW, Yuan C, Wentzel JJ (2007) Plaque rupture in the carotid artery is localized at the high shear stress region: a case report. Stroke 38:2379\u20132381","journal-title":"Stroke"},{"issue":"7","key":"1197_CR14","doi-asserted-by":"crossref","first-page":"071006","DOI":"10.1115\/1.4001265","volume":"132","author":"Y Hoi","year":"2010","unstructured":"Hoi Y, Wasserman BA, Lakatta EG, Steinman DA (2010) Carotid bifurcation hemodynamics in older adults: effect of measured vs. assumed. J Biomech Eng 132(7):071006","journal-title":"J Biomech Eng"},{"key":"1197_CR15","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1056\/NEJM200006083422302","volume":"342","author":"D Inzitari","year":"2000","unstructured":"Inzitari D, Eliasziw M, Gates P, Sharpe BL, Chan RK, Meldrum HE, Barnett HJ (2000) The causes and risk of stroke in patients with asymptomatic internal carotid artery stenosis. N Engl J Med 342:1693\u20131701","journal-title":"N Engl J Med"},{"issue":"6","key":"1197_CR16","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jvs.2005.02.044","volume":"41","author":"AS Jahromi","year":"2005","unstructured":"Jahromi AS, Cin\u00e0 CS, Liu Y, Clase CM (2005) Sensitivity and specificity of color duplex ultrasound measurement in the estimation of internal carotid artery stenosis: a systematic review and meta-analysis. J Vasc Surg 41(6):962\u2013972","journal-title":"J Vasc Surg"},{"key":"1197_CR17","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1016\/j.cma.2009.02.012","volume":"198","author":"HJ Kim","year":"2009","unstructured":"Kim HJ, Figueroa CA, Hughes TJR, Jansen KE, Taylor CA (2009) Augmented Lagrangian method for constraining the shape of velocity profiles at outlet boundaries for three-dimensional finite element simulations of blood flow. Comput Methods Appl Mech Eng 198:3551\u20133566","journal-title":"Comput Methods Appl Mech Eng"},{"issue":"3","key":"1197_CR18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1161\/01.ATV.5.3.293","volume":"5","author":"DN Ku","year":"1985","unstructured":"Ku DN, Giddens DP, Zarins CK, Glagov S (1985) Pulsatile flow and atherosclerosis in the human carotid bifurcation\u2014positive correlation between plaque location and low and oscillating shear-stress. Arteriosclerosis 5(3):293\u2013302","journal-title":"Arteriosclerosis"},{"issue":"11","key":"1197_CR19","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1109\/TIP.2008.2004611","volume":"17","author":"S Lanktom","year":"2008","unstructured":"Lanktom S, Tannenbaum A (2008) Localizing region-based active contours. IEEE Trans Image Process 17(11):2029\u20132039","journal-title":"IEEE Trans Image Process"},{"issue":"457","key":"1197_CR20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1198\/016214502753479392","volume":"97","author":"L Lin","year":"2002","unstructured":"Lin L, Hedayat AS, Sinha B, Yang M (2002) Statistical methods in assessing agreement. J Am Stat Assoc 97(457):257\u2013270","journal-title":"J Am Stat Assoc"},{"key":"1197_CR21","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.medengphy.2004.08.013","volume":"26","author":"KW Lee","year":"2004","unstructured":"Lee KW, Wood NB, Xu XY (2004) Ultrasound image-based computer model of a common carotid artery with a plaque. Med Eng Phys 26:823\u2013840","journal-title":"Med Eng Phys"},{"issue":"2","key":"1197_CR22","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1115\/1.2540836","volume":"129","author":"SW Lee","year":"2007","unstructured":"Lee SW, Steinman DA (2007) On the relative importance of rheology for image-based CFD models of the carotid bifurcation. ASME J Biomech Eng 129(2):273\u2013278","journal-title":"ASME J Biomech Eng"},{"issue":"8","key":"1197_CR23","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1161\/STROKEAHA.107.510644","volume":"39","author":"SW Lee","year":"2008","unstructured":"Lee SW, Antiga L, Spence JD, Steinman DA (2008) Geometry of the carotid bifurcation predicts its exposure to disturbed flow. Stroke 39(8):2341\u20132347","journal-title":"Stroke"},{"issue":"6","key":"1197_CR24","doi-asserted-by":"crossref","first-page":"061013","DOI":"10.1115\/1.3127252","volume":"131","author":"SW Lee","year":"2009","unstructured":"Lee SW, Antiga L, Steinman DA (2009) Correlations among indicators of disturbed flow at the normal carotid bifurcation. J Biomech Eng 131(6):061013","journal-title":"J Biomech Eng"},{"issue":"1","key":"1197_CR25","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s11517-006-0140-3","volume":"45","author":"CP Loizou","year":"2007","unstructured":"Loizou CP, Pattichis CS, Pantziaris M, Tyllis T, Nicolaides A (2007) Snakes based segmentation of the common carotid artery intima media. Med Biol Eng Comput 45(1):35\u201349","journal-title":"Med Biol Eng Comput"},{"key":"1197_CR26","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1001\/jama.282.21.2035","volume":"282","author":"AM Malek","year":"1999","unstructured":"Malek AM, Alper SL, Izumo S (1999) Hemodynamic shear stress and its role in atherosclerosis. JAMA 282:2035\u20132042","journal-title":"JAMA"},{"issue":"9","key":"1197_CR27","doi-asserted-by":"crossref","first-page":"091005","DOI":"10.1115\/1.4001886","volume":"132","author":"U Morbiducci","year":"2010","unstructured":"Morbiducci U, Gallo D, Massai D, Consolo F, Ponzini R, Antiga L, Bignardi C, Deriu MA, Redaelli A (2010) Outflow conditions for image-based hemodynamic models of the carotid bifurcation: implication for indicators of abnormal flow. J Biomech Eng 132(9):091005","journal-title":"J Biomech Eng"},{"issue":"13","key":"1197_CR28","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.jbiomech.2011.06.028","volume":"44","author":"U Morbiducci","year":"2011","unstructured":"Morbiducci U, Gallo D, Massai D, Ponzini R, Deriu MA, Antiga L, Redaelli A, Montevecchi FM (2011) On the importance of blood rheology for bulk flow in hemodynamic models of the carotid bifurcation. J Biomech 44(13):2427\u20132438","journal-title":"J Biomech"},{"issue":"5","key":"1197_CR29","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/10255840500264742","volume":"8","author":"J M\u00fcller","year":"2005","unstructured":"M\u00fcller J, Sahni O, Li X, Jansen KE, Shephard MS, Taylor CA (2005) Anisotropic adaptive finite element method for modelling blood flow. Comput Methods Biomech Biomed Engin 8(5):295\u2013305","journal-title":"Comput Methods Biomech Biomed Engin"},{"issue":"15","key":"1197_CR30","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1016\/j.jbiomech.2013.08.003","volume":"46","author":"V Peiffer","year":"2013","unstructured":"Peiffer V, Sherwin SJ, Weinberg PD (2013) Computation in the rabbit aorta of a new metric\u2014the transverse wall shear stress\u2014to quantify the multidirectional character of disturbed blood flow. J Biomech 46(15):2651\u20132658","journal-title":"J Biomech"},{"issue":"4","key":"1197_CR31","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1115\/1.2895428","volume":"113","author":"K Perktold","year":"1991","unstructured":"Perktold K, Resch M, Florian H (1991) Pulsatile non-Newtonian flow characteristics in a three-dimensional human carotid bifurcation model. J Biomech Eng 113(4):464\u2013475","journal-title":"J Biomech Eng"},{"issue":"3","key":"1197_CR32","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1148\/radiology.208.3.9722841","volume":"208","author":"JF Polak","year":"1998","unstructured":"Polak JF, Shemanski L, O\u2019L\u2019ary DH, Lefkowitz D, Price TR, Savage PJ, Brant WE, Reid C (1998) Hypoechoic plaque at US of the carotid artery: an independent risk factor for incident stroke in adults aged 65\u00a0years or older. Cardiovascular Health Study. Radiology 208(3):649\u2013654","journal-title":"Radiology"},{"issue":"suppl 1","key":"1197_CR33","first-page":"77","volume":"33","author":"A Santos","year":"2012","unstructured":"Santos A, Sousa L, Tavares J, Santos R, Castro P, Azevedo E (2012) Computer simulation of the carotid artery. Cerebrovasc Dis 33(suppl 1):77\u201377","journal-title":"Cerebrovasc Dis"},{"issue":"16","key":"1197_CR34","doi-asserted-by":"crossref","first-page":"6570","DOI":"10.1016\/j.eswa.2013.06.003","volume":"40","author":"A Santos","year":"2013","unstructured":"Santos A, Santos R, Castro P, Azevedo E, Sousa L, Tavares J (2013) A novel automatic algorithm for the segmentation of the lumen of the carotid artery in ultrasound B-mode images. Expert Syst Appl 40(16):6570\u20136579","journal-title":"Expert Syst Appl"},{"key":"1197_CR35","volume-title":"Ultrasonography in vascular diagnosis","author":"W Sch\u00e4berle","year":"2004","unstructured":"Sch\u00e4berle W (2004) Ultrasonography in vascular diagnosis. Springer, Berlin, Heidelberg"},{"key":"1197_CR36","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1016\/j.jbiomech.2008.03.038","volume":"41","author":"EL Seung","year":"2008","unstructured":"Seung EL, Lee SW, Fischerc PF, Bassiounyd HS, Lothe F (2008) Direct numerical simulation of transitional flow in a stenosed carotid bifurcation. J Biomech 41:2551\u20132561","journal-title":"J Biomech"},{"issue":"4","key":"1197_CR37","first-page":"1109","volume":"8","author":"LC Sousa","year":"2011","unstructured":"Sousa LC, Castro CF, Ant\u00f3nio CAC, Chaves R (2011) Computational Techniques and Validation of Blood Flow Simulation. WSEAS TRANSACTIONS Biol Biomed 8(4):1109\u20139518","journal-title":"WSEAS TRANSACTIONS Biol Biomed"},{"key":"1197_CR38","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1016\/j.jbiomech.2012.07.033","volume":"45","author":"LC Sousa","year":"2012","unstructured":"Sousa LC, Castro CF, Ant\u00f3nio CAC, Chaves R (2012) Blood flow simulation and vascular reconstruction. J Biomech 45:2549\u20132555","journal-title":"J Biomech"},{"key":"1197_CR39","unstructured":"Sousa LC, Castro CF, Antonio CAC (2012) Blood flow simulation and applications. In: Natal JRM., Tavares JMRS, Barbosa MP, Slade AP (eds) Technologies for medical sciences: lecture notes in computational vision and biomechanics. Springer, Netherlands, 1 p 67\u20138637"},{"issue":"5","key":"1197_CR40","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/jcu.10078","volume":"30","author":"IN Staikov","year":"2002","unstructured":"Staikov IN, Nedeltchev K, Arnold M, Remonda L, Schroth G, Sturzenegger M, Herrmann C, Rivoir A, Mattle HP (2002) Duplex sonographic criteria for measuring carotid stenoses. J Clin Ultrasound 30(5):275\u2013281","journal-title":"J Clin Ultrasound"},{"issue":"2","key":"1197_CR41","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.jvs.2005.10.069","volume":"43","author":"MC Stoner","year":"2006","unstructured":"Stoner MC, Abbott WM, Wong DR, Hua HT, Lamuraglia GM, Kwolek CJ, Watkins MT, Agnihotri AK, Henderson WG, Khuri S, Cambria RP (2006) Defining the high-risk patient for carotid endarterectomy: an analysis of the prospective National Surgical Quality Improvement Program database. J Vasc Surg 43(2):285\u2013295","journal-title":"J Vasc Surg"},{"issue":"1","key":"1197_CR42","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1109\/TMI.2011.2165959","volume":"31","author":"A Swillens","year":"2012","unstructured":"Swillens A, De Santis G, Degroote J, Lovstakken L, Vierendeels J, Segers P (2012) Accuracy of carotid strain estimates from ultrasonic wall tracking: a study based on multiphysics simulations and In vivo data. IEEE Trans Med Imaging 31(1):131\u2013138","journal-title":"IEEE Trans Med Imaging"},{"issue":"4","key":"1197_CR43","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.jbiomech.2007.11.026","volume":"41","author":"DL Tang","year":"2008","unstructured":"Tang DL, Yang C, Mondal S, Liu F, Canton G, Hatsukami TS, Yuan C (2008) A negative correlation between human carotid atherosclerotic plaque progression and plaque wall stress: in Vivo MRI-based 2d\/3d FSI models. J Biomech 41(4):727\u2013736","journal-title":"J Biomech"},{"issue":"11","key":"1197_CR44","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1161\/01.STR.0000185726.83152.00","volume":"36","author":"BA Wasserman","year":"2005","unstructured":"Wasserman BA, Wityk RJ, Trout HH, Virmani R (2005) Low-grade carotid stenosis: looking beyond the lumen with MRI. Stroke 36(11):2504\u20132513","journal-title":"Stroke"},{"issue":"3","key":"1197_CR45","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1113\/jphysiol.1955.sp005276","volume":"127","author":"JR Womersley","year":"1955","unstructured":"Womersley JR (1955) Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known. J Physiol 127(3):553\u2013563","journal-title":"J Physiol"},{"issue":"1","key":"1197_CR46","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.jbiomech.2011.10.001","volume":"45","author":"C Zhang","year":"2012","unstructured":"Zhang C, Xie S, Li S, Pu F, Deng X, Fan Y, Li D (2012) Flow patterns and wall shear stress distribution in human internal carotid arteries: the geometric effect on the risk for stenoses. J Biomech 45(1):83\u201389","journal-title":"J Biomech"},{"key":"1197_CR47","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/S0021-9290(02)00185-9","volume":"35","author":"SZ Zhao","year":"2002","unstructured":"Zhao SZ, Xu XY, Ariff B, Long Q, Stanton AV, Hughes AD, Thom SA (2002) Inter-individual variations in wall shear stress and mechanical stress distributions at the carotid artery bifurcation of healthy humans. J Biomech 35:1367\u20131377","journal-title":"J Biomech"}],"container-title":["Medical &amp; Biological Engineering &amp; Computing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-014-1197-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s11517-014-1197-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s11517-014-1197-z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T12:10:25Z","timestamp":1559391025000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s11517-014-1197-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,24]]},"references-count":47,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["1197"],"URL":"https:\/\/doi.org\/10.1007\/s11517-014-1197-z","relation":{},"ISSN":["0140-0118","1741-0444"],"issn-type":[{"value":"0140-0118","type":"print"},{"value":"1741-0444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,24]]}}}