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Because the peripheral nerves, the neuromuscular junction and motor neurons exhibit degenerative features during advanced age, sarcopenia does not seem to intrinsically develop, but is rather a secondary effect of impaired neuronal function. It is therefore recommended that elderly subjects undergo an exercise program that is aimed towards the improvement of coordinative skills and of muscle strength.<\/jats:p>","DOI":"10.1007\/s11556-006-0011-9","type":"journal-article","created":{"date-parts":[[2006,8,21]],"date-time":"2006-08-21T07:09:24Z","timestamp":1156144164000},"page":"75-83","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Ceasing of muscle function with aging: is it the consequence of intrinsic muscle degeneration or a secondary effect of neuronal impairments?"],"prefix":"10.1007","volume":"3","author":[{"given":"P. A.","family":"Figueiredo","sequence":"first","affiliation":[]},{"given":"M. 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