{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T12:50:35Z","timestamp":1760014235762},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1-2","license":[{"start":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T00:00:00Z","timestamp":1238630400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"},{"start":{"date-parts":[[2009,4,2]],"date-time":"2009-04-02T00:00:00Z","timestamp":1238630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Mol Neurosci"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1007\/s12031-009-9192-9","type":"journal-article","created":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T14:04:32Z","timestamp":1238594672000},"page":"248-255","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["\u0391\u03b2 Hinders Nuclear Targeting of AICD and Fe65 in Primary Neuronal Cultures"],"prefix":"10.1007","volume":"39","author":[{"given":"A. G.","family":"Henriques","sequence":"first","affiliation":[]},{"given":"S. I.","family":"Vieira","sequence":"additional","affiliation":[]},{"given":"E. F.","family":"da Cruz e Silva","sequence":"additional","affiliation":[]},{"given":"O. A. B.","family":"da Cruz e Silva","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2009,4,2]]},"reference":[{"key":"9192_CR1","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1002\/jnr.10737","volume":"74","author":"T. M. Allinson","year":"2003","unstructured":"Allinson, T. M., Parkin, E. T., Turner, A. J., & Hooper, N. M. (2003). ADAMs family members as amyloid precursor protein alpha-secretases. Journal of Neuroscience Research, 74, 342\u2013352. doi:10.1002\/jnr.10737.","journal-title":"Journal of Neuroscience Research"},{"key":"9192_CR2","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.ntt.2003.12.007","volume":"26","author":"F. C. Amador","year":"2004","unstructured":"Amador, F. C., Henriques, A. G., da Cruz, E. S. O. A., & da Cruz, E. S. E. F. (2004). Monitoring protein phosphatase 1 isoform levels as a marker for cellular stress. Neurotoxicology and Teratology, 26, 387\u2013395. doi:10.1016\/j.ntt.2003.12.007.","journal-title":"Neurotoxicology and Teratology"},{"key":"9192_CR3","doi-asserted-by":"publisher","first-page":"40353","DOI":"10.1074\/jbc.M106460200","volume":"276","author":"K. Ando","year":"2001","unstructured":"Ando, K., Iijima, K. I., Elliott, J. I., Kirino, Y., & Suzuki, T. (2001). Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid. The Journal of Biological Chemistry, 276, 40353\u201340361. doi:10.1074\/jbc.M106460200.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR4","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0092-8674(02)00809-7","volume":"110","author":"S. H. Baek","year":"2002","unstructured":"Baek, S. H., Ohgi, K. A., Rose, D. W., Koo, E. H., Glass, C. K., & Rosenfeld, M. G. (2002). Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell, 110, 55\u201367. doi:10.1016\/S0092-8674(02)00809-7.","journal-title":"Cell"},{"key":"9192_CR5","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1002\/jnr.490350513","volume":"35","author":"G. J. Brewer","year":"1993","unstructured":"Brewer, G. J., Torricelli, J. R., Evege, E. K., & Price, P. J. (1993). Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. Journal of Neuroscience Research, 35, 567\u2013576. doi:10.1002\/jnr.490350513.","journal-title":"Journal of Neuroscience Research"},{"key":"9192_CR6","doi-asserted-by":"publisher","first-page":"27765","DOI":"10.1074\/jbc.273.43.27765","volume":"273","author":"J. D. Buxbaum","year":"1998","unstructured":"Buxbaum, J. D., Liu, K. N., Luo, Y., Slack, J. L., Stocking, K. L., Peschon, J. J., et al. (1998). Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor. The Journal of Biological Chemistry, 273, 27765\u201327767. doi:10.1074\/jbc.273.43.27765.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR7","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1126\/science.1058783","volume":"293","author":"X. Cao","year":"2001","unstructured":"Cao, X., & Sudhof, T. C. (2001). A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60. Science, 293, 115\u2013120. doi:10.1126\/science.1058783.","journal-title":"Science"},{"key":"9192_CR8","doi-asserted-by":"publisher","first-page":"6471","DOI":"10.1074\/jbc.M409106200","volume":"280","author":"A. Capell","year":"2005","unstructured":"Capell, A., Beher, D., Prokop, S., Steiner, H., Kaether, C., Shearman, M. S., et al. (2005). Gamma-secretase complex assembly within the early secretory pathway. The Journal of Biological Chemistry, 280, 6471\u20136478. doi:10.1074\/jbc.M409106200.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR9","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1016\/S0197-4580(00)00172-X","volume":"21","author":"C. D. Carlson","year":"2000","unstructured":"Carlson, C. D., Czilli, D. L., & Gitter, B. D. (2000). Regulation of amyloid precursor protein processing by Abeta in human glioma cells. Neurobiology of Aging, 21, 747\u2013756. doi:10.1016\/S0197-4580(00)00172-X.","journal-title":"Neurobiology of Aging"},{"key":"9192_CR10","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1385\/JMN:23:1-2:123","volume":"23","author":"O. A. da Cruz e Silva","year":"2004","unstructured":"da Cruz e Silva, O. A., Fardilha, M., Henriques, A. G., Rebelo, S., Vieira, S., & da Cruz e Silva, E. F. (2004). Signal transduction therapeutics: relevance for Alzheimer\u2019s disease. Journal of Molecular Neuroscience, 23, 123\u2013142. doi:10.1385\/JMN:23:1-2:123.","journal-title":"Journal of Molecular Neuroscience"},{"key":"9192_CR11","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1471-4159.2008.05770.x","volume":"108","author":"O. da Cruz e Silva","year":"2009","unstructured":"da Cruz e Silva, O., Rebelo, S., Vieira, S., Gandy, S., da Cruz e Silva, E. F., & Greengard, P. F. (2009). Enhanced generation of Alzheimer\u2019s Abeta following chronic exposure to phorbol ester correlates with differential effects on alpha and epsilon isozymes of protein kinase C. Journal of Neurochemistry, 108, 309\u2013330.","journal-title":"Journal of Neurochemistry"},{"key":"9192_CR12","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1046\/j.1471-4159.1995.65020931.x","volume":"65","author":"J. Davis-Salinas","year":"1995","unstructured":"Davis-Salinas, J., Saporito-Irwin, S. M., Cotman, C. W., & Van Nostrand, W. E. (1995). Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. Journal of Neurochemistry, 65, 931\u2013934.","journal-title":"Journal of Neurochemistry"},{"key":"9192_CR13","doi-asserted-by":"publisher","first-page":"2720","DOI":"10.1073\/pnas.052436599","volume":"99","author":"W. P. Esler","year":"2002","unstructured":"Esler, W. P., Kimberly, W. T., Ostaszewski, B. L., Ye, W., Diehl, T. S., Selkoe, D. J., et al. (2002). Activity-dependent isolation of the presenilin-gamma-secretase complex reveals nicastrin and a gamma substrate. Proceedings of the National Academy of Sciences of the United States of America, 99, 2720\u20132725. doi:10.1073\/pnas.052436599.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"9192_CR14","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1038\/359322a0","volume":"359","author":"C. Haass","year":"1992","unstructured":"Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., et al. (1992). Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature, 359, 322\u2013325. doi:10.1038\/359322a0.","journal-title":"Nature"},{"key":"9192_CR15","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/j.1749-6632.1993.tb23037.x","volume":"695","author":"C. Haass","year":"1993","unstructured":"Haass, C., Hung, A. Y., Schlossmacher, M. G., Oltersdorf, T., Teplow, D. B., & Selkoe, D. J. (1993). Normal cellular processing of the beta-amyloid precursor protein results in the secretion of the amyloid beta peptide and related molecules. Annals of the New York Academy of Sciences, 695, 109\u2013116. doi:10.1111\/j.1749-6632.1993.tb23037.x.","journal-title":"Annals of the New York Academy of Sciences"},{"key":"9192_CR16","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3233\/JAD-2007-11112","volume":"11","author":"A. G. Henriques","year":"2007","unstructured":"Henriques, A. G., Vieira, S. I., Rebelo, S., Domingues, S. C., da Cruz e Silva, E. F., & da Cruz e Silva, O. A. (2007). Isoform specific amyloid-beta protein precursor metabolism. Journal of Alzheimer's Disease, 11, 85\u201395.","journal-title":"Journal of Alzheimer's Disease"},{"key":"9192_CR17","doi-asserted-by":"crossref","unstructured":"Henriques, A., Vieira, S. I., Crespo-L\u00f3pez, E., Oliveira, M., Da Cruz e Silva, E. F., & Da Cruz e Silva, O. A. B. (2009) Intracellular sAPPalpha retention in response to Abeta is mapped to cytoskeleton associated structure. Journal of Neuroscience Research, 87(6), 1449\u20131461.","DOI":"10.1002\/jnr.21959"},{"key":"9192_CR18","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1111\/j.1600-0854.2006.00396.x","volume":"7","author":"C. Kaether","year":"2006","unstructured":"Kaether, C., Schmitt, S., Willem, M., & Haass, C. (2006). Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface. Traffic (Copenhagen, Denmark), 7, 408\u2013415. doi:10.1111\/j.1600-0854.2006.00396.x.","journal-title":"Traffic (Copenhagen, Denmark)"},{"key":"9192_CR19","first-page":"1951","volume":"17","author":"H. S. Kim","year":"2003","unstructured":"Kim, H. S., Kim, E. M., Lee, J. P., Park, C. H., Kim, S., Seo, J. H., et al. (2003). C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression. The FASEB Journal, 17, 1951\u20131953.","journal-title":"The FASEB Journal"},{"key":"9192_CR20","doi-asserted-by":"crossref","first-page":"40288","DOI":"10.1074\/jbc.C100447200","volume":"276","author":"W. T. Kimberly","year":"2001","unstructured":"Kimberly, W. T., Zheng, J. B., Guenette, S. Y., & Selkoe, D. J. (2001). The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner. The Journal of Biological Chemistry, 276, 40288\u201340292.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR21","doi-asserted-by":"publisher","first-page":"2373","DOI":"10.1046\/j.1471-4159.1995.65052373.x","volume":"65","author":"W. Le","year":"1995","unstructured":"Le, W., Xie, W. J., Nyormoi, O., Ho, B. K., Smith, R. G., & Appel, S. H. (1995). Beta-amyloid1\u201340 increases expression of beta-amyloid precursor protein in neuronal hybrid cells. Journal of Neurochemistry, 65, 2373\u20132376.","journal-title":"Journal of Neurochemistry"},{"key":"9192_CR22","doi-asserted-by":"publisher","first-page":"45013","DOI":"10.1074\/jbc.M208164200","volume":"277","author":"S. F. Lee","year":"2002","unstructured":"Lee, S. F., Shah, S., Li, H., Yu, C., Han, W., & Yu, G. (2002). Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch. The Journal of Biological Chemistry, 277, 45013\u201345019. doi:10.1074\/jbc.M208164200.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR23","doi-asserted-by":"publisher","first-page":"6138","DOI":"10.1073\/pnas.110126897","volume":"97","author":"Y. M. Li","year":"2000","unstructured":"Li, Y. M., Lai, M. T., Xu, M., Huang, Q., DiMuzio-Mower, J., Sardana, M. K., et al. (2000). Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state. Proceedings of the National Academy of Sciences of the United States of America, 97, 6138\u20136143. doi:10.1073\/pnas.110126897.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"9192_CR24","doi-asserted-by":"publisher","first-page":"6545","DOI":"10.1074\/jbc.M007340200","volume":"276","author":"G. Minopoli","year":"2001","unstructured":"Minopoli, G., de Candia, P., Bonetti, A., Faraonio, R., Zambrano, N., & Russo, T. (2001). The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation. The Journal of Biological Chemistry, 276, 6545\u20136550. doi:10.1074\/jbc.M007340200.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR25","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1002\/(SICI)1097-4547(19980615)52:6<661::AID-JNR5>3.0.CO;2-6","volume":"52","author":"M. T. Moreno-Flores","year":"1998","unstructured":"Moreno-Flores, M. T., Salinero, O., & Wandosell, F. (1998). BetaA amyloid peptide (25\u201335) induced APP expression in cultured astrocytes. Journal of Neuroscience Research, 52, 661\u2013671. doi:10.1002\/(SICI)1097-4547(19980615)52:6<661::AID-JNR5>3.0.CO;2-6.","journal-title":"Journal of Neuroscience Research"},{"key":"9192_CR26","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/j.neuron.2005.04.008","volume":"46","author":"R. Pardossi-Piquard","year":"2005","unstructured":"Pardossi-Piquard, R., Petit, A., Kawarai, T., Sunyach, C., Alves da Costa, C., Vincent, B., et al. (2005). Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. Neuron, 46, 541\u2013554. doi:10.1016\/j.neuron.2005.04.008.","journal-title":"Neuron"},{"key":"9192_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12031-007-0001-z","volume":"32","author":"S. Rebelo","year":"2007","unstructured":"Rebelo, S., Vieira, S. I., Esselmann, H., Wiltfang, J., da Cruz e Silva, E. F., & da Cruz e Silva, O. A. (2007). Tyr687 dependent APP endocytosis and Abeta production. Journal of Molecular Neuroscience, 32, 1\u20138. doi:10.1007\/s12031-007-0001-z.","journal-title":"Journal of Molecular Neuroscience"},{"key":"9192_CR28","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1083\/jcb.200505078","volume":"171","author":"K. A. Ryan","year":"2005","unstructured":"Ryan, K. A., & Pimplikar, S. W. (2005). Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain. The Journal of Cell Biology, 171, 327\u2013335. doi:10.1083\/jcb.200505078.","journal-title":"The Journal of Cell Biology"},{"key":"9192_CR29","doi-asserted-by":"publisher","first-page":"7952","DOI":"10.1074\/jbc.274.12.7952","volume":"274","author":"S. L. Sabo","year":"1999","unstructured":"Sabo, S. L., Lanier, L. M., Ikin, A. F., Khorkova, O., Sahasrabudhe, S., Greengard, P., et al. (1999). Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein. The Journal of Biological Chemistry, 274, 7952\u20137957. doi:10.1074\/jbc.274.12.7952.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR30","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1093\/embo-reports\/kve180","volume":"2","author":"M. Sastre","year":"2001","unstructured":"Sastre, M., Steiner, H., Fuchs, K., Capell, A., Multhaup, G., Condron, M. M., et al. (2001). Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch. EMBO Reports, 2, 835\u2013841. doi:10.1093\/embo-reports\/kve180.","journal-title":"EMBO Reports"},{"key":"9192_CR31","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1006\/excr.1997.3606","volume":"234","author":"T. L. Schmitt","year":"1997","unstructured":"Schmitt, T. L., Steiner, E., Trieb, K., & Grubeck-Loebenstein, B. (1997). Amyloid beta-protein(25\u201335) increases cellular APP and inhibits the secretion of APPs in human extraneuronal cells. Experimental Cell Research, 234, 336\u2013340. doi:10.1006\/excr.1997.3606.","journal-title":"Experimental Cell Research"},{"key":"9192_CR32","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/0166-2236(93)90008-A","volume":"16","author":"D. J. Selkoe","year":"1993","unstructured":"Selkoe, D. J. (1993). Physiological production of the beta-amyloid protein and the mechanism of Alzheimer\u2019s disease. Trends in Neurosciences, 16, 403\u2013409. doi:10.1016\/0166-2236(93)90008-A.","journal-title":"Trends in Neurosciences"},{"key":"9192_CR33","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1046\/j.1471-4159.2002.00901.x","volume":"81","author":"N. Sergeant","year":"2002","unstructured":"Sergeant, N., David, J. P., Champain, D., Ghestem, A., Wattez, A., & Delacourte, A. (2002). Progressive decrease of amyloid precursor protein carboxy terminal fragments (APP-CTFs), associated with tau pathology stages, in Alzheimer\u2019s disease. Journal of Neurochemistry, 81, 663\u2013672. doi:10.1046\/j.1471-4159.2002.00901.x.","journal-title":"Journal of Neurochemistry"},{"key":"9192_CR34","doi-asserted-by":"publisher","first-page":"6075","DOI":"10.1073\/pnas.89.13.6075","volume":"89","author":"S. S. Sisodia","year":"1992","unstructured":"Sisodia, S. S. (1992). Beta-amyloid precursor protein cleavage by a membrane-bound protease. Proceedings of the National Academy of Sciences of the United States of America, 89, 6075\u20136079. doi:10.1073\/pnas.89.13.6075.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"9192_CR35","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1126\/science.286.5440.735","volume":"286","author":"R. Vassar","year":"1999","unstructured":"Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., et al. (1999). Beta-secretase cleavage of Alzheimer\u2019s amyloid precursor protein by the transmembrane aspartic protease BACE. Science, 286, 735\u2013741. doi:10.1126\/science.286.5440.735.","journal-title":"Science"},{"key":"9192_CR36","doi-asserted-by":"publisher","first-page":"4435","DOI":"10.1242\/jcs.01323","volume":"117","author":"R. C. von Rotz","year":"2004","unstructured":"von Rotz, R. C., Kohli, B. M., Bosset, J., Meier, M., Suzuki, T., Nitsch, R. M., et al. (2004). The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. Journal of Cell Science, 117, 4435\u20134448. doi:10.1242\/jcs.01323.","journal-title":"Journal of Cell Science"},{"key":"9192_CR37","doi-asserted-by":"publisher","first-page":"6664","DOI":"10.1021\/bi027375c","volume":"42","author":"D. M. Walsh","year":"2003","unstructured":"Walsh, D. M., Fadeeva, J. V., LaVoie, M. J., Paliga, K., Eggert, S., Kimberly, W. T., et al. (2003). Gamma-secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins. Biochemistry, 42, 6664\u20136673. doi:10.1021\/bi027375c.","journal-title":"Biochemistry"},{"key":"9192_CR38","doi-asserted-by":"publisher","first-page":"4318","DOI":"10.1074\/jbc.M609293200","volume":"282","author":"Z. Xie","year":"2007","unstructured":"Xie, Z., Dong, Y., Maeda, U., Xia, W., & Tanzi, R. E. (2007). RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation. The Journal of Biological Chemistry, 282, 4318\u20134325. doi:10.1074\/jbc.M609293200.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR39","doi-asserted-by":"publisher","first-page":"36788","DOI":"10.1074\/jbc.M104350200","volume":"276","author":"R. Yan","year":"2001","unstructured":"Yan, R., Han, P., Miao, H., Greengard, P., & Xu, H. (2001). The transmembrane domain of the Alzheimer\u2019s beta-secretase (BACE1) determines its late Golgi localization and access to beta-amyloid precursor protein (APP) substrate. The Journal of Biological Chemistry, 276, 36788\u201336796. doi:10.1074\/jbc.M104350200.","journal-title":"The Journal of Biological Chemistry"},{"key":"9192_CR40","doi-asserted-by":"publisher","first-page":"14786","DOI":"10.1074\/jbc.270.24.14786","volume":"270","author":"A. J. Yang","year":"1995","unstructured":"Yang, A. J., Knauer, M., Burdick, D. A., & Glabe, C. (1995). Intracellular A beta 1\u201342 aggregates stimulate the accumulation of stable, insoluble amyloidogenic fragments of the amyloid precursor protein in transfected cells. The Journal of Biological Chemistry, 270, 14786\u201314792. doi:10.1074\/jbc.270.24.14786.","journal-title":"The Journal of Biological Chemistry"}],"container-title":["Journal of Molecular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-009-9192-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12031-009-9192-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-009-9192-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12031-009-9192-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T20:16:32Z","timestamp":1630440992000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12031-009-9192-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4,2]]},"references-count":40,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["9192"],"URL":"https:\/\/doi.org\/10.1007\/s12031-009-9192-9","relation":{},"ISSN":["0895-8696","1559-1166"],"issn-type":[{"value":"0895-8696","type":"print"},{"value":"1559-1166","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,4,2]]},"assertion":[{"value":"17 October 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 January 2009","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2009","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}