{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T04:05:29Z","timestamp":1768363529191,"version":"3.49.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Germany, Federal Ministry of Education and Research","award":["01ED1602A\/B"],"award-info":[{"award-number":["01ED1602A\/B"]}]},{"name":"Germany, Federal Ministry of Education and Research","award":["01ED1602A\/B"],"award-info":[{"award-number":["01ED1602A\/B"]}]},{"name":"Germany, Federal Ministry of Education and Research","award":["01ED1602A\/B"],"award-info":[{"award-number":["01ED1602A\/B"]}]},{"name":"Germany, Federal Ministry of Education and Research","award":["01ED1602A\/B"],"award-info":[{"award-number":["01ED1602A\/B"]}]},{"name":"Netherlands, The Netherlands Organisation for Health Research and Development"},{"name":"Portugal, Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["JPCOFUND\/0002\/2015"],"award-info":[{"award-number":["JPCOFUND\/0002\/2015"]}]},{"name":"Portugal, Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["JPCOFUND\/0002\/2015"],"award-info":[{"award-number":["JPCOFUND\/0002\/2015"]}]},{"name":"Portugal, Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["JPCOFUND\/0002\/2015"],"award-info":[{"award-number":["JPCOFUND\/0002\/2015"]}]},{"name":"Portugal, Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["JPCOFUND\/0002\/2015"],"award-info":[{"award-number":["JPCOFUND\/0002\/2015"]}]},{"name":"United Kingdom, Medical Research Council"},{"DOI":"10.13039\/100008382","name":"Fundo Regional para a Ci\u00eancia e Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008382","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["CEECIND\/03018\/2018\/CP1556\/CT0009"],"award-info":[{"award-number":["CEECIND\/03018\/2018\/CP1556\/CT0009"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cerebellum"],"DOI":"10.1007\/s12311-025-01911-1","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T07:40:48Z","timestamp":1758872448000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Article Title: Impact of Dysphagia on Quality of Life in Machado-Joseph Disease"],"prefix":"10.1007","volume":"24","author":[{"given":"Joana Paz","family":"Mota","sequence":"first","affiliation":[]},{"given":"In\u00eas Tello","family":"Rodrigues","sequence":"additional","affiliation":[]},{"given":"Ana Filipa","family":"Ferreira","sequence":"additional","affiliation":[]},{"given":"Ana Rosa Vieira","family":"Melo","sequence":"additional","affiliation":[]},{"given":"Paula","family":"Pires","sequence":"additional","affiliation":[]},{"given":"Pedro","family":"Lopes","sequence":"additional","affiliation":[]},{"given":"Jo\u00e3o","family":"Vasconcelos","sequence":"additional","affiliation":[]},{"given":"Mafalda","family":"Raposo","sequence":"additional","affiliation":[]},{"given":"Manuela","family":"Lima","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2025,9,26]]},"reference":[{"key":"1911_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1750-1172-6-35","volume":"6","author":"C Bettencourt","year":"2011","unstructured":"Bettencourt C, Lima M. Machado-Joseph disease: from first descriptions to new perspectives. Orphanet J Rare Dis. 2011;6:1\u201312.","journal-title":"Orphanet J Rare Dis"},{"key":"1911_CR2","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1159\/000358801","volume":"42","author":"L Ruano","year":"2014","unstructured":"Ruano L, Melo C, Silva MC, Coutinho P. The global epidemiology of hereditary ataxia and spastic paraplegia: a systematic review of prevalence studies. Neuroepidemiology. 2014;42:174\u201383.","journal-title":"Neuroepidemiology"},{"key":"1911_CR3","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/S1474-4422(04)00737-9","volume":"3","author":"L Sch\u00f6ls","year":"2004","unstructured":"Sch\u00f6ls L, Bauer P, Schmidt T, Schulte T, Riess O. Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. Lancet Neurol. 2004;3:291\u2013304.","journal-title":"Lancet Neurol"},{"key":"1911_CR4","first-page":"1001","volume":"1","author":"MA Ara\u00fajo","year":"2016","unstructured":"Ara\u00fajo MA, De, Raposo M, Kazachkova N, Vasconcelos J, Kay T, Lima M. Trends in the epidemiology of spinocerebellar ataxia type 3 \/ Machado-Joseph disease in the Azores islands, Portugal. JSM Brain Sci. 2016;1:1001.","journal-title":"JSM Brain Sci"},{"issue":"2","key":"1911_CR5","doi-asserted-by":"publisher","first-page":"247","DOI":"10.3390\/biomedicines11020247","volume":"11","author":"M Lima","year":"2023","unstructured":"Lima M, Raposo M, Ferreira A, Rosa A, Melo V, Pav S, Medeiros F, Gonzalez C, Pires P, Lopes P, Valverde D, Gonzalez J, Kay T. The homogeneous Azorean Machado-Joseph disease cohort: characterization and contributions to advances in research. Biomedicines. 2023;11(2):247.","journal-title":"Biomedicines"},{"key":"1911_CR6","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1038\/ng1194-221","volume":"8","author":"Y Kawaguchi","year":"1994","unstructured":"Kawaguchi Y, Okamoto T, Taniwaki M, Aizawa M, Inoue M, Katayama S, Kawakami H, Nakamura S, Nishimura M, Akiguchi I, Kimura J, Narumiya S, Kakizuka A. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nat Genet. 1994;8:221\u20138.","journal-title":"Nat Genet"},{"key":"1911_CR7","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1038\/ng0793-300","volume":"4","author":"Y Takiyama","year":"1993","unstructured":"Takiyama Y, Nishizawa M, Tanaka H, Kawashia S, Sakamoto H, Karabu Y, Shimazaki H, Soutome M, Endo K, Ohta S, Kagawa Y, Kanazawa I, Mizuno Y, Yoshida M, Yuasa T, Horikawa Y, Oyanagi K, Nagai H, Kondo T, Tsuji S. The gene for Machado-Joseph disease maps to human chromosome 14q. Nat Genet. 1993;4:300\u20134.","journal-title":"Nat Genet"},{"key":"1911_CR8","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1212\/WNL.28.7.703","volume":"28","author":"P Coutinho","year":"1987","unstructured":"Coutinho P, Andrade C. Autosomal dominant system degeneration in Portuguese families of the Azores Islands. Neurology. 1987;28:703.","journal-title":"Neurology"},{"key":"1911_CR9","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/978-3-319-71779-1_11","volume":"1049","author":"AH Koeppen","year":"2018","unstructured":"Koeppen AH. The neuropathology of spinocerebellar ataxia type 3\/machado-joseph disease. Adv Exp Med Biol. 2018;1049:233\u201341.","journal-title":"Adv Exp Med Biol"},{"key":"1911_CR10","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/j.1468-1331.2009.02757.x","volume":"17","author":"J Vale","year":"2010","unstructured":"Vale J, Bugalho P, Silveira I, Sequeiros J, Guimar\u00e3es J, Coutinho P. Autosomal dominant cerebellar ataxia: frequency analysis and clinical characterization of 45 families from Portugal. Eur J Neurol. 2010;17:124\u20138.","journal-title":"Eur J Neurol"},{"key":"1911_CR11","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1001\/archneur.58.6.899","volume":"58","author":"LB Jardim","year":"2001","unstructured":"Jardim LB, Pereira ML, Silveira I, Ferro A, Sequeiros J, Giugliani R. Neurologic findings in Machado-Joseph disease: relaion with disease duration, subtypes, and (CAG)n. Arch Neurol. 2001;58:899\u2013904.","journal-title":"Arch Neurol"},{"key":"1911_CR12","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.pneurobio.2013.01.001","volume":"104","author":"U R\u00fcb","year":"2013","unstructured":"R\u00fcb U, Sch\u00f6ls L, Paulson H, Auburger G, Kermer P, Jen JC, Seidel K, Korf HW, Deller T. Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7. Prog Neurobiol. 2013;104:38\u201366.","journal-title":"Prog Neurobiol"},{"key":"1911_CR13","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1007\/s12311-020-01122-w","volume":"19","author":"M R\u00f6nnefarth","year":"2020","unstructured":"R\u00f6nnefarth M, Hanisch N, Brandt AU, M\u00e4hler A, Endres M, Paul F, et al. Dysphagia affecting quality of life in cerebellar ataxia\u2014a large survey. Cerebellum. 2020;19:437\u201345.","journal-title":"Cerebellum"},{"key":"1911_CR14","doi-asserted-by":"publisher","first-page":"E194","DOI":"10.1212\/WNL.0000000000009776","volume":"95","author":"AP Vogel","year":"2020","unstructured":"Vogel AP, Magee M, Torres-Vega R, Medrano-Montero J, Cyngler MP, Kruse M, Rojas S, Cubillos SC, Canento T, Maldonado F, Vazquez-Mojena Y, Ilg W, Rodr\u00edguez-Labrada R, Vel\u00e1zquez-P\u00e9rez L, Synofzik M. Features of speech and swallowing dysfunction in pre-ataxic spinocerebellar ataxia type 2. Neurology. 2020;95:E194\u2013205.","journal-title":"Neurology"},{"key":"1911_CR15","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s12311-008-0013-4","volume":"7","author":"O Riess","year":"2008","unstructured":"Riess O, R\u00fcb U, Pastore A, Bauer P, Sch\u00f6ls L. SCA3: neurological features, pathogenesis and animal models. Cerebellum. 2008;7:125\u201337.","journal-title":"Cerebellum"},{"key":"1911_CR16","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1002\/mdc3.12173","volume":"2","author":"AD Russo","year":"2015","unstructured":"Russo AD, Reckziegel ER, Krum-Santos AC, Augustin MC, Scheeren B, Freitas CD, et al. Clinical scales predict significant videofluoroscopic dysphagia in Machado Joseph disease patients. Mov Disord Clin Pract. 2015;2:260\u20136.","journal-title":"Mov Disord Clin Pract"},{"key":"1911_CR17","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1001\/archneur.1997.00550210011007","volume":"54","author":"L Sch\u00f6ls","year":"1997","unstructured":"Sch\u00f6ls L, Gispert S, Vorgerd M, Vieira-Saecker M, Blanke AM, Auburger P, Amoiridis G, Meves G, Epplen S, Przuntek JT, Pulst H, S. M., Riess O. Spinocerebellar ataxia type 2: genotype and phenotype in German kindreds. Arch Neurol. 1997;54:1073\u201380.","journal-title":"Arch Neurol"},{"key":"1911_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2020.116878","volume":"415","author":"CY Yang","year":"2020","unstructured":"Yang CY, Lai RY, Amokrane N, Lin CY, Figueroa KP, Pulst SM, et al. Dysphagia in spinocerebellar ataxias type 1, 2, 3 and 6. J Neurol Sci. 2020;415:116878.","journal-title":"J Neurol Sci"},{"key":"1911_CR19","unstructured":"Wolf AE. Aspectos cl\u00ednicos Da degluti\u00e7\u00e3o, Da fonoarticula\u00e7\u00e3o e Suas correla\u00e7\u00f5es Gen\u00e9ticas Na Doen\u00e7a de Machado Joseph. Universidade Estadual De Campinas (UNICAMP) 2008."},{"key":"1911_CR20","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1590\/S0004-28032010000400003","volume":"47","author":"SMA Corr\u00eaa","year":"2010","unstructured":"Corr\u00eaa SMA, Felix VN, Gurgel GL, Sallum RAA, Cecconello I. Clinical evaluation of oropharyngeal dysphagia in Machado-Joseph disease. Arq Gastroenterol. 2010;47:334\u20138.","journal-title":"Arq Gastroenterol"},{"key":"1911_CR21","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1111\/j.1365-2990.2006.00772.x","volume":"32","author":"U R\u00fcb","year":"2006","unstructured":"R\u00fcb U, Brunt ER, Petrasch-Parwez E, Sch\u00f6ls L, Theegarten D, Auburger G, Seidel K, Schultz C, Gierga K, Paulson H, Van Broeckhoven C, Deller T. De vos, R. A. I. Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7. Neuropathol Appl Neurobiol. 2006;32:635\u201349.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"1911_CR22","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1159\/000442252","volume":"74","author":"C Isono","year":"2015","unstructured":"Isono C, Hirano M, Sakamoto H, Ueno S, Kusunoki S, Nakamura Y. Differential progression of dysphagia in heredity and sporadic ataxias involving multiple systems. Eur Neurol. 2015;74:237\u201342.","journal-title":"Eur Neurol"},{"key":"1911_CR23","doi-asserted-by":"crossref","unstructured":"Ekberg O, Hamdy S, Woisard V, Wuttge-Hannig A, Ortega P. (2002). Social and psychological burden of dysphagia: Its impact on diagnosis and treatment. Dysphagia 2002;17:139\u2013146.","DOI":"10.1007\/s00455-001-0113-5"},{"key":"1911_CR24","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1212\/01.wnl.0000219042.60538.92","volume":"66","author":"T Schmitz-H\u00fcbsch","year":"2006","unstructured":"Schmitz-H\u00fcbsch T, Montcel D, Baliko ST, Berciano L, Boesch J, Depondt S, Giunti C, Globas P, Infante C. Kang. Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology. 2006;66:1717\u201320.","journal-title":"Neurology"},{"issue":"1","key":"1911_CR25","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1212\/WNL.0000000000001711","volume":"85","author":"RPPWM Maas","year":"2015","unstructured":"Maas RPPWM, Van Gaalen J, Klockgether T, Van De Warrenburg BPC. The preclinical stage of spinocerebellar ataxias. Neurology. 2015;85(1):96\u2013103. https:\/\/doi.org\/10.1212\/WNL.0000000000001711.","journal-title":"Neurology"},{"key":"1911_CR26","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1007\/s12311-012-0421-3","volume":"12","author":"H Jacobi","year":"2013","unstructured":"Jacobi H, Rakowicz M, Rola R, Fancellu R, Mariotti C, Charles P, et al. Inventory of non-ataxia signs (INAS): validation of a new clinical assessment instrument. Cerebellum. 2013;12:418\u201328.","journal-title":"Cerebellum"},{"key":"1911_CR27","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1002\/mds.28844","volume":"37","author":"H Hengel","year":"2022","unstructured":"Hengel H, Martus P, Faber J, Garcia-moreno H, Solanky N, Giunti P, Klockgether T, Reetz K, Warrenburg BP, Van De, Almeida LP, Al E. Characterization of lifestyle in spinocerebellar ataxia type 3 and association with disease severity. Mov Disord. 2022;37:405\u201310.","journal-title":"Mov Disord"},{"key":"1911_CR28","doi-asserted-by":"crossref","unstructured":"Subramony SH, May W, Lynch D, Gomez C, Fischbeck K, Hallett M, Taylor P, Wilson R, Ashizawa T. (2005). Measuring Friedreich ataxia: Interrater reliability of a neurologic rating scale. Neurology 2005;64:1261\u20131262.","DOI":"10.1212\/01.WNL.0000156802.15466.79"},{"key":"1911_CR29","first-page":"6","volume":"29","author":"EB Antunes","year":"2015","unstructured":"Antunes EB, Vieira D, Dinis-Ribeiro M. Linguistic and cultural adaptation into European Portuguese of swal-qol and swal-care outcomes tool for adults with oropharyngeal dysphagia. Arq Med. 2015;29:6\u201310.","journal-title":"Arq Med"},{"key":"1911_CR30","unstructured":"Moreira S. Tradu\u00e7\u00e3o e valida\u00e7\u00e3o da EAT-10 e da FOIS para o Portugu\u00eas. 2012."},{"key":"1911_CR31","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1007\/s00455-015-9630-5","volume":"30","author":"DS Nogueira","year":"2015","unstructured":"Nogueira DS, Ferreira PL, Reis EA, Lopes IS. Measuring outcomes for dysphagia: validity and reliability of the European Portuguese eating assessment tool (P-EAT-10). Dysphagia. 2015;30:511\u201320.","journal-title":"Dysphagia"},{"key":"1911_CR32","unstructured":"Queir\u00f3s A, Moreira S, Silva A, Costa R, Lains J. (2013). Contributo para a Adapta\u00e7\u00e3o e Valida\u00e7\u00e3o da Eat Assessment Tool (EAT-10) e da Functional Oral Intake Scale (FOIS). Revista Da Sociedade Portuguesa de Medicina F\u00edsica e de Reabilita\u00e7\u00e3o 2013;24:25\u201330."},{"key":"1911_CR33","unstructured":"Dias C. Functional Oral Intake Scale (FOIS):contributo para a valida\u00e7\u00e3o cultural e lingu\u00edstica para o portugu\u00eas Europeu 2015."},{"key":"1911_CR34","unstructured":"Matos MdaA, Bou\u00e7a C, Batista J, Mestre S, Dias T. Portuguese Version of the V-VST: Content Validation. 5th European Society of Swallowing Disorders (ESSD) Congress 2015."},{"key":"1911_CR35","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00455-001-0109-1","volume":"17","author":"CA McHorney","year":"2002","unstructured":"McHorney CA, Robbins JA, Lomax K, Rosenbek JC, Chignell K, Kramer AE, et al. The SWAL-QOL and SWAL-CARE outcomes tool for oropharyngeal dysphagia in adults: III. documentation of reliability and validity. Dysphagia. 2002;17:97\u2013114.","journal-title":"Dysphagia"},{"key":"1911_CR36","doi-asserted-by":"crossref","unstructured":"Belafsky PC, Mouadeb DA, Rees CJ, Pryor JC, Postman GN, Allen J, Leonard RJ. (2008). Validity and Reliability of the Eating Assessment Tool (EAT-10). Ann Otol Rhinol Laryngol 2008;177:1919\u20131924.","DOI":"10.1177\/000348940811701210"},{"key":"1911_CR37","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1016\/j.apmr.2004.11.049","volume":"86","author":"MA Crary","year":"2005","unstructured":"Crary MA, Mann C, G. D., Groher ME. Initial psychometric assessment of a functional oral intake scale for dysphagia in stroke patients. Arch Phys Med Rehabil. 2005;86:1516\u201320.","journal-title":"Arch Phys Med Rehabil"},{"key":"1911_CR38","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1016\/j.clnu.2008.06.011","volume":"27","author":"P Clav\u00e9","year":"2008","unstructured":"Clav\u00e9 P, Arreola V, Romea M, Medina L, Palomera E, Serra-Prat M. Accuracy of the volume-viscosity swallow test for clinical screening of oropharyngeal dysphagia and aspiration. Clin Nutr. 2008;27:806\u201315.","journal-title":"Clin Nutr"},{"key":"1911_CR39","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1080\/13803395.2011.589374","volume":"33","author":"S Freitas","year":"2011","unstructured":"Freitas S, Sim\u00f5es MR, Alves L, Santana I. Journal of clinical and experimental neuropsychology Montreal cognitive assessment (MoCA): normative study for the Portuguese population Montreal cognitive assessment (MoCA): normative study for the Portuguese population. J Clin Exp Neuropsychol. 2011;33:989\u201396.","journal-title":"J Clin Exp Neuropsychol"},{"key":"1911_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1046\/j.1365-2990.2003.00437.x","volume":"29","author":"U R\u00fcb","year":"2003","unstructured":"R\u00fcb U, Bruntt ER, Del Turco D, De Vos RAI, Gierga K, Paulson H, Braak H. Guidelines for the pathoanatomical examination of the lower brain stem in ingestive and swallowing disorders and its application to a dysphagic spinocerebellar ataxia type 3 patient. Neuropathol Appl Neurobiol. 2003;29:1\u201313.","journal-title":"Neuropathol Appl Neurobiol"},{"key":"1911_CR41","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1007\/s00455-013-9450-4","volume":"28","author":"C Isono","year":"2013","unstructured":"Isono C, Hirano M, Sakamoto H, Ueno S, Kusunoki S, Nakamura Y. Differences in dysphagia between spinocerebellar ataxia type 3 and type 6. Dysphagia. 2013;28:413\u20138.","journal-title":"Dysphagia"}],"container-title":["The Cerebellum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-025-01911-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12311-025-01911-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12311-025-01911-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T20:03:32Z","timestamp":1768334612000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12311-025-01911-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,26]]},"references-count":41,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["1911"],"URL":"https:\/\/doi.org\/10.1007\/s12311-025-01911-1","relation":{},"ISSN":["1473-4230"],"issn-type":[{"value":"1473-4230","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,26]]},"assertion":[{"value":"15 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This work is an outcome of ESMI, an EU Joint Programme - Neurodegenerative Disease Research (JPND) project. The ESMI project was supported through the following funding organisations under the aegis of JPND: Germany, Federal Ministry of Education and Research (BMBF; funding codes 01ED1602A\/B); Netherlands, The Netherlands Organisation for Health Research and Development; Portugal, Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT; funding codes JPCOFUND\/0002\/2015); United Kingdom, Medical Research Council. The Fundo Regional para a Ci\u00eancia e Tecnologia (FRCT, Governo Regional dos A\u00e7ores) has supported ESMI in Azores, under the PRO-SCIENTIA program. MR is supported by Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (\n                      \n                      ). Approval was obtained from the ethics committee of University of the Azores, Hospital do Divino Esp\u00edrito Santo and Hospital do Santo Esp\u00edrito da Ilha Terceira. The procedures used in this study adhere to the tenets of the Declaration of Helsinki. All participants signed the informed consent form on paper which was treated in is codified form.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"158"}}