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This article discusses the changes that are needed in research to drive this paradigm shift and to go from a \u201closses and waste\u201d situation to a \u201cresource and opportunities\u201d ambition. The current lines of research aim to maximise the use and value of biomass or organic residues and wastewater and propose new organisational schemes driven by technical innovations. Exploring the pathways to a sustainable future through many domains let us identify five challenges to structure the research efforts and find circular bioeconomy solutions for organic residues and wastewater: (1) proposing innovative processes and integrated multi-process systems; (2) promoting the emergence of multi-scale and cross-sectoral organisations; (3) developing multi-performance evaluation methods, (4) rethinking research\u2013society intersections, and (5) enhancing research\u2013legislation interactions. We end by outlining prospects for moving forward past current limitations: beyond increasing knowledge, research will continue its own transition. Our responsibility today is not to think about what we could do for a better world but what we should do to make our ever-changing world even better and more sustainable.<\/jats:p>\n                <jats:p><jats:bold>Graphic Abstract<\/jats:bold><\/jats:p>","DOI":"10.1007\/s12649-021-01549-0","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T17:07:14Z","timestamp":1629824834000},"page":"1267-1276","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Circular Economy Applied to Organic Residues and Wastewater: Research Challenges"],"prefix":"10.1007","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9088-1232","authenticated-orcid":false,"given":"B\u00e9n\u00e9dicte","family":"Bakan","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2710-3547","authenticated-orcid":false,"given":"Nicolas","family":"Bernet","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2236-8282","authenticated-orcid":false,"given":"Th\u00e9odore","family":"Bouchez","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8373-1831","authenticated-orcid":false,"given":"Rachel","family":"Boutrou","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7717-1102","authenticated-orcid":false,"given":"Jean-Marc","family":"Choubert","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6124-2316","authenticated-orcid":false,"given":"Patrick","family":"Dabert","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2655-0310","authenticated-orcid":false,"given":"Christian","family":"Duquennoi","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4815-0297","authenticated-orcid":false,"given":"Vincenza","family":"Ferraro","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3163-8819","authenticated-orcid":false,"given":"Diana","family":"Garc\u00eda-Bernet","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9152-8710","authenticated-orcid":false,"given":"Sylvie","family":"Gillot","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5091-0569","authenticated-orcid":false,"given":"Jacques","family":"Mery","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7513-0190","authenticated-orcid":false,"given":"Caroline","family":"R\u00e9mond","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0467-8081","authenticated-orcid":false,"given":"Jean-Philippe","family":"Steyer","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7041-2962","authenticated-orcid":false,"given":"Eric","family":"Trably","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6394-615X","authenticated-orcid":false,"given":"Anne","family":"Tremier","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2021,8,24]]},"reference":[{"key":"1549_CR1","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.resconrec.2017.06.009","volume":"125","author":"G Calvo","year":"2017","unstructured":"Calvo, G., Valero, A., Valero, A.: Assessing maximum production peak and resource availability of non-fuel mineral resources: analyzing the influence of extractable global resources. 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