{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:21:46Z","timestamp":1787808106371,"version":"build-2784847793"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Mindfulness"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s12671-026-02877-9","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T05:59:58Z","timestamp":1779861598000},"page":"2516-2526","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dynamic Methylation Changes in Alzheimer\u2019s Disease-Related Genes During Mindfulness Practice \u2013 a Proof-of-Concept Study"],"prefix":"10.1007","volume":"17","author":[{"given":"Idoia","family":"Blanco-Luquin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Mac\u00edas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibai","family":"Marro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Puebla-Guedea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blanca","family":"Acha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johana","family":"\u00c1lvarez-Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Razquin-Sola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miren","family":"Roldan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eneko","family":"Cabezon-Arteta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Gonz\u00e1lez-Villena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Montero-Mar\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Garc\u00eda-Campayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maite","family":"Mendioroz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"issue":"23","key":"2877_CR1","doi-asserted-by":"publisher","first-page":"e2434","DOI":"10.1212\/WNL.0000000000207865","volume":"101","author":"B Acha","year":"2023","unstructured":"Acha, B., Corroza, J., S\u00e1nchez-Ruiz de Gordoa, J., Cabello, C., Robles, M., M\u00e9ndez-L\u00f3pez, I., Mac\u00edas, M., Zueco, S., Roldan, M., Urd\u00e1noz-Casado, A., Jeric\u00f3, I., Erro, M. E., Alcolea, D., Lleo, A., Blanco-Luquin, I., & Mendioroz, M. (2023). Association of blood-based DNA methylation markers with late-onset Alzheimer disease: A potential diagnostic approach. Neurology, 101(23), e2434\u2013e2447. https:\/\/doi.org\/10.1212\/WNL.0000000000207865","journal-title":"Neurology"},{"issue":"3","key":"2877_CR2","doi-asserted-by":"publisher","first-page":"872","DOI":"10.4049\/jimmunol.1501944","volume":"197","author":"H Al Sadoun","year":"2016","unstructured":"Al Sadoun, H., Burgess, M., Hentges, K. E., & Mace, K. A. (2016). Enforced expression of Hoxa3 inhibits classical and promotes alternative activation of macrophages in vitro and in vivo. Journal of Immunology, 197(3), 872\u2013884. https:\/\/doi.org\/10.4049\/jimmunol.1501944","journal-title":"Journal of Immunology"},{"issue":"1","key":"2877_CR3","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s13148-019-0672-7","volume":"11","author":"M Altuna","year":"2019","unstructured":"Altuna, M., Urdanoz-Casado, A., Sanchez-Ruiz de Gordoa, J., Zelaya, M. V., Labarga, A., Lepesant, J. M. J., Roldan, M., Blanco-Luquin, I., Perdones, A., Larumbe, R., Jerico, I., Echavarri, C., Mendez-Lopez, I., Di Stefano, L., & Mendioroz, M. (2019). DNA methylation signature of human hippocampus in Alzheimer\u2019s disease is linked to neurogenesis. Clinical Epigenetics, 11(1), Article 91. https:\/\/doi.org\/10.1186\/s13148-019-0672-7","journal-title":"Clinical Epigenetics"},{"key":"2877_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpnec.2022.100152","volume":"11","author":"MJ \u00c1lvarez-L\u00f3pez","year":"2022","unstructured":"\u00c1lvarez-L\u00f3pez, M. J., Conklin, Q. A., Cos\u00edn-Tom\u00e1s, M., Shields, G. S., King, B. G., Zanesco, A. P., Kaliman, P., & Saron, C. D. (2022). Changes in the expression of inflammatory and epigenetic-modulatory genes after an intensive meditation retreat. Comprehensive Psychoneuroendocrinology, 11, Article 100152. https:\/\/doi.org\/10.1016\/j.cpnec.2022.100152","journal-title":"Comprehensive Psychoneuroendocrinology"},{"issue":"2","key":"2877_CR5","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1002\/alz.13514","volume":"20","author":"C Breen","year":"2024","unstructured":"Breen, C., Papale, L. A., Clark, L. R., Bergmann, P. E., Madrid, A., Asthana, S., Johnson, S. C., Keles, S., Alisch, R. S., & Hogan, K. J. (2024). Whole genome methylation sequencing in blood identifies extensive differential DNA methylation in late-onset dementia due to Alzheimer\u2019s disease. Alzheimer\u2019s & Dementia, 20(2), 1050\u20131062. https:\/\/doi.org\/10.1002\/alz.13514","journal-title":"Alzheimer\u2019s & Dementia"},{"issue":"4","key":"2877_CR6","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1037\/0022-3514.84.4.822","volume":"84","author":"KW Brown","year":"2003","unstructured":"Brown, K. W., & Ryan, R. M. (2003). The benefits of being present: Mindfulness and its role in psychological well-being. Journal of Personality and Social Psychology, 84(4), 822\u2013848. https:\/\/doi.org\/10.1037\/0022-3514.84.4.822","journal-title":"Journal of Personality and Social Psychology"},{"issue":"12","key":"2877_CR7","doi-asserted-by":"publisher","first-page":"2037","DOI":"10.1016\/j.psyneuen.2012.04.003","volume":"37","author":"KW Brown","year":"2012","unstructured":"Brown, K. W., Weinstein, N., & Creswell, J. D. (2012). Trait mindfulness modulates neuroendocrine and affective responses to social evaluative threat. Psychoneuroendocrinology, 37(12), 2037\u20132041. https:\/\/doi.org\/10.1016\/j.psyneuen.2012.04.003","journal-title":"Psychoneuroendocrinology"},{"key":"2877_CR8","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.bbi.2019.11.003","volume":"84","author":"R Chaix","year":"2020","unstructured":"Chaix, R., Fagny, M., Cosin-Tomas, M., Alvarez-Lopez, M., Lemee, L., Regnault, B., Davidson, R. J., Lutz, A., & Kaliman, P. (2020). Differential DNA methylation in experienced meditators after an intensive day of mindfulness-based practice: Implications for immune-related pathways. Brain, Behavior, and Immunity, 84, 36\u201344. https:\/\/doi.org\/10.1016\/j.bbi.2019.11.003","journal-title":"Brain, Behavior, and Immunity"},{"issue":"3","key":"2877_CR9","doi-asserted-by":"publisher","first-page":"2863","DOI":"10.3892\/etm.2020.9025","volume":"20","author":"WD Chen","year":"2020","unstructured":"Chen, W. D., Song, T., Cao, Q. H., Li, R., Wang, H., Chen, X. B., & Chen, Z. T. (2020). Atherosclerosis prediction by microarray-based DNA methylation analysis. Experimental and Therapeutic Medicine, 20(3), 2863\u20132869. https:\/\/doi.org\/10.3892\/etm.2020.9025","journal-title":"Experimental and Therapeutic Medicine"},{"issue":"8","key":"2877_CR10","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1017\/S0033291709991747","volume":"40","author":"A Chiesa","year":"2010","unstructured":"Chiesa, A., & Serretti, A. (2010). A systematic review of neurobiological and clinical features of mindfulness meditations. Psychological Medicine, 40(8), 1239\u20131252. https:\/\/doi.org\/10.1017\/S0033291709991747","journal-title":"Psychological Medicine"},{"key":"2877_CR11","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1222863","volume":"14","author":"NN Dasanayaka","year":"2023","unstructured":"Dasanayaka, N. N., Sirisena, N. D., & Samaranayake, N. (2023). Associations of meditation with telomere dynamics: A case-control study in healthy adults. Frontiers in Psychology, 14, Article 1222863. https:\/\/doi.org\/10.3389\/fpsyg.2023.1222863","journal-title":"Frontiers in Psychology"},{"issue":"5","key":"2877_CR12","doi-asserted-by":"publisher","first-page":"3629","DOI":"10.1002\/alz.13805","volume":"20","author":"L Duchateau","year":"2024","unstructured":"Duchateau, L., Wawrzyniak, N., & Sleegers, K. (2024). The ABC\u2019s of Alzheimer risk gene ABCA7. Alzheimer\u2019s & Dementia, 20(5), 3629\u20133648. https:\/\/doi.org\/10.1002\/alz.13805","journal-title":"Alzheimer's & Dementia"},{"key":"2877_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.1056507","volume":"14","author":"RJ Elsworthy","year":"2022","unstructured":"Elsworthy, R. J., Hill, E. J., Dunleavy, C., & Aldred, S. (2022). The role of ADAM10 in astrocytes: Implications for Alzheimer\u2019s disease. Frontiers in Aging Neuroscience, 14, Article 1056507. https:\/\/doi.org\/10.3389\/fnagi.2022.1056507","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"4","key":"2877_CR14","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1016\/j.celrep.2015.12.077","volume":"14","author":"J Friedrich","year":"2016","unstructured":"Friedrich, J., Sorge, S., Bujupi, F., Eichenlaub, M. P., Schulz, N. G., Wittbrodt, J., & Lohmann, I. (2016). Hox function is required for the development and maintenance of the Drosophila feeding motor unit. Cell Reports, 14(4), 850\u2013860. https:\/\/doi.org\/10.1016\/j.celrep.2015.12.077","journal-title":"Cell Reports"},{"issue":"4","key":"2877_CR15","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1007\/s12671-017-0851-6","volume":"9","author":"J Garc\u00eda-Campayo","year":"2018","unstructured":"Garc\u00eda-Campayo, J., Puebla-Guedea, M., Labarga, A., Urd\u00e1noz, A., Rold\u00e1n, M., Pulido, L., de Morentin, X. M., Perdones-Montero, \u00c1., Montero-Mar\u00edn, J., & Mendioroz, M. (2018). Epigenetic response to mindfulness in peripheral blood leukocytes involves genes linked to common human diseases. Mindfulness, 9(4), 1146\u20131159. https:\/\/doi.org\/10.1007\/s12671-017-0851-6","journal-title":"Mindfulness"},{"issue":"9","key":"2877_CR16","doi-asserted-by":"publisher","first-page":"4954","DOI":"10.1172\/JCI138179","volume":"130","author":"M Gratuze","year":"2020","unstructured":"Gratuze, M., Leyns, C. E., Sauerbeck, A. D., St-Pierre, M. K., Xiong, M., Kim, N., Serrano, J. R., Tremblay, M., Kummer, T. T., Colonna, M., Ulrich, J. D., & Holtzman, D. M. (2020). Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration. Journal of Clinical Investigation, 130(9), 4954\u20134968. https:\/\/doi.org\/10.1172\/JCI138179","journal-title":"Journal of Clinical Investigation"},{"issue":"1","key":"2877_CR17","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.pscychresns.2010.08.006","volume":"191","author":"BK H\u00f6lzel","year":"2011","unstructured":"H\u00f6lzel, B. K., Carmody, J., Vangel, M., Congleton, C., Yerramsetti, S. M., Gard, T., & Lazar, S. W. (2011). Mindfulness practice leads to increases in regional brain gray matter density. Psychiatry Research, 191(1), 36\u201343. https:\/\/doi.org\/10.1016\/j.pscychresns.2010.08.006","journal-title":"Psychiatry Research"},{"key":"2877_CR18","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00040","volume":"5","author":"KE Innes","year":"2014","unstructured":"Innes, K. E., & Selfe, T. K. (2014). Meditation as a therapeutic intervention for adults at risk for Alzheimer\u2019s disease: Potential benefits and underlying mechanisms. Frontiers in Psychiatry, 5, Article 40. https:\/\/doi.org\/10.3389\/fpsyt.2014.00040","journal-title":"Frontiers in Psychiatry"},{"key":"2877_CR19","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/927509","author":"KE Innes","year":"2012","unstructured":"Innes, K. E., Selfe, T. K., Brown, C. J., Rose, K. M., & Thompson-Heisterman, A. (2012). The effects of meditation on perceived stress and related indices of psychological status and sympathetic activation in persons with Alzheimer\u2019s disease and their caregivers: A pilot study. Evidence-Based Complementary and Alternative Medicine, Article\u00a0927509. https:\/\/doi.org\/10.1155\/2012\/927509","journal-title":"Evidence-Based Complementary and Alternative Medicine"},{"issue":"8","key":"2877_CR20","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1002\/gps.4076","volume":"29","author":"FA Jain","year":"2014","unstructured":"Jain, F. A., Nazarian, N., & Lavretsky, H. (2014). Feasibility of central meditation and imagery therapy for dementia caregivers. International Journal of Geriatric Psychiatry, 29(8), 870\u2013876. https:\/\/doi.org\/10.1002\/gps.4076","journal-title":"International Journal of Geriatric Psychiatry"},{"issue":"4","key":"2877_CR21","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/BF00844934","volume":"11","author":"J Kabat-Zinn","year":"1988","unstructured":"Kabat-Zinn, J., & Chapman-Waldrop, A. (1988). Compliance with an outpatient stress reduction program: Rates and predictors of program completion. Journal of Behavioral Medicine, 11(4), 333\u2013352. https:\/\/doi.org\/10.1007\/BF00844934","journal-title":"Journal of Behavioral Medicine"},{"issue":"6","key":"2877_CR22","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.jpsychores.2015.03.009","volume":"78","author":"B Khoury","year":"2015","unstructured":"Khoury, B., Sharma, M., Rush, S. E., & Fournier, C. (2015). Mindfulness-based stress reduction for healthy individuals: A meta-analysis. Journal of Psychosomatic Research, 78(6), 519\u2013528. https:\/\/doi.org\/10.1016\/j.jpsychores.2015.03.009","journal-title":"Journal of Psychosomatic Research"},{"key":"2877_CR23","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5340717","author":"A Lardone","year":"2018","unstructured":"Lardone, A., Liparoti, M., Sorrentino, P., Rucco, R., Jacini, F., Polverino, A., Minino, R., Pesoli, M., Baselice, F., Sorriso, A., Ferraioli, G., Sorrentino, G., & Mandolesi, L. (2018). Mindfulness meditation is related to long-lasting changes in hippocampal functional topology during resting state: A magnetoencephalography study. Neural Plasticity, Article 5340717. https:\/\/doi.org\/10.1155\/2018\/5340717","journal-title":"Neural Plasticity"},{"issue":"2","key":"2877_CR24","doi-asserted-by":"publisher","first-page":"783","DOI":"10.3233\/JAD-220701","volume":"90","author":"J Lin","year":"2022","unstructured":"Lin, J., Yang, S., Wang, C., Yu, E., Zhu, Z., Shi, J., Li, X., Xin, J., Chen, X., & Pan, X. (2022). Prediction of Alzheimer\u2019s disease using patterns of methylation levels in key immunologic-related genes. Journal of Alzheimer\u2019s Disease, 90(2), 783\u2013794. https:\/\/doi.org\/10.3233\/JAD-220701","journal-title":"Journal of Alzheimer\u2019s Disease"},{"issue":"11","key":"2877_CR25","doi-asserted-by":"publisher","first-page":"1350","DOI":"10.1001\/jama.300.11.1350","volume":"300","author":"DS Ludwig","year":"2008","unstructured":"Ludwig, D. S., & Kabat-Zinn, J. (2008). Mindfulness in medicine. Journal of the American Medical Association, 300(11), 1350\u20131352. https:\/\/doi.org\/10.1001\/jama.300.11.1350","journal-title":"Journal of the American Medical Association"},{"issue":"1","key":"2877_CR26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61241-6","volume":"10","author":"M Mendioroz","year":"2020","unstructured":"Mendioroz, M., Puebla-Guedea, M., Montero-Mar\u00edn, J., Urd\u00e1noz-Casado, A., Blanco-Luquin, I., Rold\u00e1n, M., Labarga, A., & Garc\u00eda-Campayo, J. (2020). Telomere length correlates with subtelomeric DNA methylation in long-term mindfulness practitioners. Scientific Reports, 10(1), Article 4564. https:\/\/doi.org\/10.1038\/s41598-020-61241-6","journal-title":"Scientific Reports"},{"issue":"3","key":"2877_CR27","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/16.3.1215","volume":"16","author":"SA Miller","year":"1988","unstructured":"Miller, S. A., Dykes, D. D., & Polesky, H. F. (1988). A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Research, 16(3), Article 1215. https:\/\/doi.org\/10.1093\/nar\/16.3.1215","journal-title":"Nucleic Acids Research"},{"key":"2877_CR28","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2016.01935","volume":"7","author":"J Montero-Marin","year":"2016","unstructured":"Montero-Marin, J., Puebla-Guedea, M., Herrera-Mercadal, P., Cebolla, A., Soler, J., Demarzo, M., Vazquez, C., Rodr\u00edguez-Bornaetxea, F., & Garc\u00eda-Campayo, J. (2016). Psychological effects of a 1-month meditation retreat on experienced meditators: The role of non-attachment. Frontiers in Psychology, 7, Article 1935. https:\/\/doi.org\/10.3389\/fpsyg.2016.01935","journal-title":"Frontiers in Psychology"},{"key":"2877_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-015-0040-9","volume":"10","author":"MM Painter","year":"2015","unstructured":"Painter, M. M., Atagi, Y., Liu, C. C., Rademakers, R., Xu, H., Fryer, J. D., & Bu, G. (2015). TREM2 in CNS homeostasis and neurodegenerative disease. Molecular Neurodegeneration, 10, Article 43. https:\/\/doi.org\/10.1186\/s13024-015-0040-9","journal-title":"Molecular Neurodegeneration"},{"key":"2877_CR30","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.neurobiolaging.2025.04.003","volume":"151","author":"LNC Pelegrini","year":"2025","unstructured":"Pelegrini, L. N. C., Manzine, P. R., Popolin, C. P., Dorta, S., Grigoli, M. M., Alexandre-Silva, V., Pedroso, R., Ramos, A. A., Pott, H., & Cominetti, M. R. (2025). Higher soluble ADAM10 plasma levels are associated with decreased cognitive performance in older adults carrying APOEepsilon4. Neurobiology of Aging, 151, 70\u201375. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2025.04.003","journal-title":"Neurobiology of Aging"},{"issue":"4","key":"2877_CR31","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1089\/jicm.2022.0713","volume":"29","author":"SU Pragya","year":"2023","unstructured":"Pragya, S. U., Pragya, S. C., Griswold, A. J., Gu, E., Mehta, N. D., Uddin, P., Veeramachaneni, P., Mehta, N., Mehta, D., & Abomoelak, B. (2023). Preksha Dhyana meditation effect on the DNA methylation signature in college students. Journal of Integrative and Complementary Medicine, 29(4), 224\u2013233. https:\/\/doi.org\/10.1089\/jicm.2022.0713","journal-title":"Journal of Integrative and Complementary Medicine"},{"issue":"1","key":"2877_CR32","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-022-00574-4","volume":"17","author":"AC Raulin","year":"2022","unstructured":"Raulin, A. C., Doss, S. V., Trottier, Z. A., Ikezu, T. C., Bu, G., & Liu, C. C. (2022). ApoE in Alzheimer\u2019s disease: Pathophysiology and therapeutic strategies. Molecular Neurodegeneration, 17(1), Article 72. https:\/\/doi.org\/10.1186\/s13024-022-00574-4","journal-title":"Molecular Neurodegeneration"},{"key":"2877_CR33","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.neurobiolaging.2020.06.023","volume":"95","author":"JAY Roubroeks","year":"2020","unstructured":"Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., K\u0142oszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Wahlund, L. O., Aarsland, D., Proitsi, P., Hodges, A., Lovestone, S., Newhouse, S. J., Dobson, R. J. B., \u2026 Lunnon, K. (2020). An epigenome-wide association study of Alzheimer\u2019s disease blood highlights robust DNA hypermethylation in the HOXB6 gene. Neurobiology of Aging, 95, 26\u201345. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2020.06.023","journal-title":"Neurobiology of Aging"},{"issue":"7","key":"2877_CR34","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1515\/revneuro-2017-0066","volume":"29","author":"J Russell-Williams","year":"2018","unstructured":"Russell-Williams, J., Jaroudi, W., Perich, T., Hoscheidt, S., El Haj, M., & Moustafa, A. A. (2018). Mindfulness and meditation: Treating cognitive impairment and reducing stress in dementia. Reviews in the Neurosciences, 29(7), 791\u2013804. https:\/\/doi.org\/10.1515\/revneuro-2017-0066","journal-title":"Reviews in the Neurosciences"},{"issue":"1","key":"2877_CR35","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23243-4","volume":"12","author":"RG Smith","year":"2021","unstructured":"Smith, R. G., Pishva, E., Shireby, G., Smith, A. R., Roubroeks, J. A. Y., Hannon, E., Wheildon, G., Mastroeni, D., Gasparoni, G., Riemenschneider, M., Giese, A., Sharp, A. J., Schalkwyk, L., Haroutunian, V., Viechtbauer, W., van den Hove, D. L. A., Weedon, M., Brokaw, D., Francis, P. T., \u2026 Lunnon, K. (2021). A meta-analysis of epigenome-wide association studies in Alzheimer\u2019s disease highlights novel differentially methylated loci across cortex. Nature Communications, 12(1), Article 3517. https:\/\/doi.org\/10.1038\/s41467-021-23243-4","journal-title":"Nature Communications"},{"issue":"1","key":"2877_CR36","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.bpsgos.2022.01.001","volume":"3","author":"C Strikwerda-Brown","year":"2023","unstructured":"Strikwerda-Brown, C., Ozlen, H., PichetBinette, A., Chapleau, M., Marchant, N. L., Breitner, J. C. S., & Villeneuve, S. (2023). Trait mindfulness is associated with less amyloid, tau, and cognitive decline in individuals at risk for Alzheimer\u2019s disease. Biological Psychiatry Global Open Science, 3(1), 130\u2013138. https:\/\/doi.org\/10.1016\/j.bpsgos.2022.01.001","journal-title":"Biological Psychiatry Global Open Science"},{"issue":"1","key":"2877_CR37","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s13142-015-0360-x","volume":"6","author":"YY Tang","year":"2016","unstructured":"Tang, Y. Y., & Leve, L. D. (2016). A translational neuroscience perspective on mindfulness meditation as a prevention strategy. Translational Behavioral Medicine, 6(1), 63\u201372. https:\/\/doi.org\/10.1007\/s13142-015-0360-x","journal-title":"Translational Behavioral Medicine"},{"key":"2877_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2021.111303","volume":"149","author":"IP Vatanabe","year":"2021","unstructured":"Vatanabe, I. P., Pedroso, R. V., Manzine, P. R., Chagas, M. H. N., de Morais Fabricio, D., Grigoli, M. M., Naves, M. A., Pott-Jr, H., & Cominetti, M. R. (2021). ADAM10: Biomarker of mild cognitive impairment but not of cognitive frailty. Experimental Gerontology, 149, Article 111303. https:\/\/doi.org\/10.1016\/j.exger.2021.111303","journal-title":"Experimental Gerontology"},{"key":"2877_CR39","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/bs.vh.2022.12.009","volume":"122","author":"L Verdone","year":"2023","unstructured":"Verdone, L., Caserta, M., Ben-Soussan, T. D., & Venditti, S. (2023). On the road to resilience: Epigenetic effects of meditation. Vitamins and Hormones, 122, 339\u2013376. https:\/\/doi.org\/10.1016\/bs.vh.2022.12.009","journal-title":"Vitamins and Hormones"},{"issue":"1","key":"2877_CR40","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s13073-015-0258-8","volume":"8","author":"CT Watson","year":"2016","unstructured":"Watson, C. T., Roussos, P., Garg, P., Ho, D. J., Azam, N., Katsel, P. L., Haroutunian, V., & Sharp, A. J. (2016). Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer\u2019s disease. Genome Medicine, 8(1), Article 5. https:\/\/doi.org\/10.1186\/s13073-015-0258-8","journal-title":"Genome Medicine"},{"key":"2877_CR41","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2016.00156","volume":"8","author":"WP Wong","year":"2016","unstructured":"Wong, W. P., Hassed, C., Chambers, R., & Coles, J. (2016). The effects of mindfulness on persons with mild cognitive impairment: Protocol for a mixed-methods longitudinal study. Frontiers in Aging Neuroscience, 8, Article 156. https:\/\/doi.org\/10.3389\/fnagi.2016.00156","journal-title":"Frontiers in Aging Neuroscience"},{"issue":"2","key":"2877_CR42","doi-asserted-by":"publisher","first-page":"303","DOI":"10.3233\/JAD-170061","volume":"58","author":"XZ Yuan","year":"2017","unstructured":"Yuan, X. Z., Sun, S., Tan, C. C., Yu, J. T., & Tan, L. (2017). The role of ADAM10 in Alzheimer\u2019s disease. Journal of Alzheimer\u2019s Disease, 58(2), 303\u2013322. https:\/\/doi.org\/10.3233\/JAD-170061","journal-title":"Journal of Alzheimer\u2019s Disease"},{"issue":"1","key":"2877_CR43","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19791-w","volume":"11","author":"L Zhang","year":"2020","unstructured":"Zhang, L., Silva, T. C., Young, J. I., Gomez, L., Schmidt, M. A., Hamilton-Nelson, K. L., Kunkle, B. W., Chen, X., Martin, E. R., & Wang, L. (2020). Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer\u2019s disease. Nature Communications, 11(1), Article 6114. https:\/\/doi.org\/10.1038\/s41467-020-19791-w","journal-title":"Nature Communications"}],"container-title":["Mindfulness"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12671-026-02877-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12671-026-02877-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12671-026-02877-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:13:43Z","timestamp":1787807623000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12671-026-02877-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":43,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["2877"],"URL":"https:\/\/doi.org\/10.1007\/s12671-026-02877-9","relation":{},"ISSN":["1868-8527","1868-8535"],"issn-type":[{"value":"1868-8527","type":"print"},{"value":"1868-8535","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,27]]},"assertion":[{"value":"18 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures performed in this study (number PI13\/0056) involving human participants were in accordance with the ethical standards of the Aragon Ethics Regional Committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":1,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All participants provided their written informed consent before participating in the study.","order":2,"name":"Ethics","label":"Informed Consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"J.M.-M. is a member of the University of Oxford Mindfulness Research Centre.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Artificial intelligence tools were used for minor language editing and citation formatting according to APA guidelines.","order":4,"name":"Ethics","label":"Use of Artificial Intelligence","group":{"name":"EthicsHeading","label":"Declarations"}}]}}