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Prod. Bioprospect."],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Antimicrobial resistance is a major global health concern, threatening the effective prevention and treatment of infections caused by microorganisms. These factors boosted the study of safe and green alternatives, with hydrosols, the by-products of essential oils extraction, emerging as promising natural antimicrobial agents. In this context, four hydrosols obtained from <jats:italic>Cupressus leylandii<\/jats:italic> A.B.\u00a0Jacks &amp; Dallim, <jats:italic>Eucalyptus globulus<\/jats:italic> Labill., <jats:italic>Aloysia citrodora<\/jats:italic> Pal\u00e1u and <jats:italic>Melissa officinalis<\/jats:italic> L. were studied. Their chemical composition comprises neral, geranial, 1,8-cineole, terpinen-4-ol, and oplopanonyl acetate, compounds with recognised antimicrobial activity. Concerning antimicrobial activity, significant differences were found using different hydrosol concentrations (10\u201320% <jats:italic>v\/v<\/jats:italic>) in comparison to a control (without hydrosol), showing the potential of the tested hydrosols to inhibit the microbial growth of <jats:italic>Escherichia coli<\/jats:italic>, <jats:italic>Staphylococcus aureus<\/jats:italic>, and <jats:italic>Candida albicans<\/jats:italic>. <jats:italic>A. citrodora<\/jats:italic> hydrosol was the most effective one, inhibiting 90% of <jats:italic>E. coli<\/jats:italic> growth and 80% of <jats:italic>C. albicans<\/jats:italic> growth, for both hydrosol concentrations (p\u2009&lt;\u20090.0001). With hydrosol concentration increase, it was possible to observe an improved antimicrobial activity with significant reductions (p\u2009&lt;\u20090.0001). The findings of this work indicate the viability of reusing and valuing the hydrosols, encouraging the development of green applications for different fields (e.g., food, agriculture, pharmaceuticals, and cosmetics).<\/jats:p>\n                <jats:p><jats:bold>Graphical Abstract<\/jats:bold><\/jats:p>","DOI":"10.1007\/s13659-023-00417-9","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T03:02:01Z","timestamp":1704164521000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Disclosing the potential of Cupressus leylandii A.B. Jacks &amp; Dallim, Eucalyptus globulus Labill., Aloysia citrodora Pal\u00e1u, and Melissa officinalis L. hydrosols as eco-friendly antimicrobial agents"],"prefix":"10.1007","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0807-3522","authenticated-orcid":false,"given":"Helo\u00edsa H. 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