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Taffeta CN Yamaguchi is a Boehringer Ingelheim employee. Liz Pearce previously worked at Boehringer Ingelheim, participated in the design of the study. Jos\u00e9 Cunha-Vaz reports grants from Bayer, Boehringer Ingelheim and Carl Zeiss Meditec and is a consultant for Alimera Sciences, Bayer, Boehringer Ingelheim, Carl Zeiss Meditec and Roche. Jos\u00e9 Cunha-Vaz is an Editorial Board member of<i> Ophthalmology and Therapy<\/i>. Jos\u00e9 Cunha-Vaz was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"The tenets of the Declaration of Helsinki were followed, and approval was obtained from the AIBILI Ethics Committee for Health (CE 240 RICHARD), and the trial was registered at ClinicalTrials.gov, identifier NCT05112445. 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