{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T21:45:36Z","timestamp":1778190336748,"version":"3.51.4"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Drugs Aging"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s40266-020-00779-6","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T02:02:28Z","timestamp":1593482548000},"page":"605-616","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Assessment of Poor Inhaler Technique in Older Patients with Asthma or COPD: A Predictive Tool for Clinical Risk and Inhaler Performance"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4201-9565","authenticated-orcid":false,"given":"Tiago","family":"Maricoto","sequence":"first","affiliation":[]},{"given":"Duarte","family":"Santos","sequence":"additional","affiliation":[]},{"given":"Catarina","family":"Carvalho","sequence":"additional","affiliation":[]},{"given":"In\u00eas","family":"Teles","sequence":"additional","affiliation":[]},{"given":"Jaime","family":"Correia-de-Sousa","sequence":"additional","affiliation":[]},{"given":"Lu\u00eds","family":"Taborda-Barata","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2020,6,30]]},"reference":[{"issue":"1","key":"779_CR1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/2045-7022-2-15","volume":"2","author":"A Sa-Sousa","year":"2012","unstructured":"Sa-Sousa A, Morais-Almeida M, Azevedo LF, et al. Prevalence of asthma in Portugal\u2014The Portuguese National Asthma survey. Clin Transl Allergy. 2012;2(1):15. https:\/\/doi.org\/10.1186\/2045-7022-2-15.","journal-title":"Clin Transl Allergy"},{"issue":"9","key":"779_CR2","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/s2213-2600(17)30293-x","volume":"5","author":"E IfHMa","year":"2017","unstructured":"IfHMa E. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990\u20132015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Respir Med. 2017;5(9):691\u2013706. https:\/\/doi.org\/10.1016\/s2213-2600(17)30293-x.","journal-title":"Lancet Respir Med"},{"key":"779_CR3","unstructured":"Reddel H, Bacharier L, Bateman E, et al. Global Strategy for Asthma Management and Prevention. https:\/\/www.ginasthma.org: Global initiative for asthma; 2019. p. 201."},{"issue":"11","key":"779_CR4","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1136\/thx.2009.113662","volume":"64","author":"J Vestbo","year":"2009","unstructured":"Vestbo J, Anderson JA, Calverley PM, et al. Adherence to inhaled therapy, mortality and hospital admission in COPD. Thorax. 2009;64(11):939\u201343. https:\/\/doi.org\/10.1136\/thx.2009.113662.","journal-title":"Thorax"},{"issue":"3","key":"779_CR5","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1378\/chest.116.3.603","volume":"116","author":"PL Enright","year":"1999","unstructured":"Enright PL, McClelland RL, Newman AB, et al. Underdiagnosis and undertreatment of asthma in the elderly. Cardiovascular Health Study Research Group. Chest. 1999;116(3):603\u201313.","journal-title":"Chest"},{"issue":"5","key":"779_CR6","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.anai.2012.02.022","volume":"108","author":"AM Smith","year":"2012","unstructured":"Smith AM, Villareal M, Bernstein DI, et al. Asthma in the elderly: risk factors and impact on physical function. Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol. 2012;108(5):305\u201310. https:\/\/doi.org\/10.1016\/j.anai.2012.02.022.","journal-title":"Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol"},{"issue":"9","key":"779_CR7","doi-asserted-by":"publisher","first-page":"1479","DOI":"10.1016\/j.rmed.2006.01.008","volume":"100","author":"GK Crompton","year":"2006","unstructured":"Crompton GK, Barnes PJ, Broeders M, et al. The need to improve inhalation technique in Europe: a report from the Aerosol Drug Management Improvement Team. Respir Med. 2006;100(9):1479\u201394. https:\/\/doi.org\/10.1016\/j.rmed.2006.01.008.","journal-title":"Respir Med"},{"key":"779_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2017.01.004","author":"DB Price","year":"2017","unstructured":"Price DB, Rom\u00e1n-Rodr\u00edguez M, McQueen RB, et al. Inhaler errors in the CRITIKAL study: type, frequency, and association with asthma outcomes. J Allergy Clin Immunol. 2017. https:\/\/doi.org\/10.1016\/j.jaip.2017.01.004.","journal-title":"J Allergy Clin Immunol."},{"issue":"1","key":"779_CR9","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1710-1492-9-8","volume":"9","author":"H Al-Jahdali","year":"2013","unstructured":"Al-Jahdali H, Ahmed A, Al-Harbi A, et al. Improper inhaler technique is associated with poor asthma control and frequent emergency department visits. Allergy Asthma Clin Immunol Off J Can Soc Allergy Clin Immunol. 2013;9(1):8\u20138. https:\/\/doi.org\/10.1186\/1710-1492-9-8.","journal-title":"Allergy Asthma Clin Immunol Off J Can Soc Allergy Clin Immunol"},{"issue":"4","key":"779_CR10","doi-asserted-by":"publisher","first-page":"429","DOI":"10.3109\/02770903.2013.871558","volume":"51","author":"S Baddar","year":"2014","unstructured":"Baddar S, Jayakrishnan B, Al-Rawas OA. Asthma control: importance of compliance and inhaler technique assessments. J Asthma Off J Assoc Care Asthma. 2014;51(4):429\u201334. https:\/\/doi.org\/10.3109\/02770903.2013.871558.","journal-title":"J Asthma Off J Assoc Care Asthma"},{"issue":"2","key":"779_CR11","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1183\/09031936.00075614","volume":"45","author":"M Engelkes","year":"2015","unstructured":"Engelkes M, Janssens HM, de Jongste JC, et al. Medication adherence and the risk of severe asthma exacerbations: a systematic review. Eur Respir J. 2015;45(2):396\u2013407. https:\/\/doi.org\/10.1183\/09031936.00075614.","journal-title":"Eur Respir J"},{"issue":"4","key":"779_CR12","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/crj.12084","volume":"8","author":"L Lurslurchachai","year":"2014","unstructured":"Lurslurchachai L, Krauskopf K, Roy A, et al. Metered dose inhaler technique among inner-city asthmatics and its association with asthma medication adherence. Clin Respir J. 2014;8(4):397\u2013403. https:\/\/doi.org\/10.1111\/crj.12084.","journal-title":"Clin Respir J"},{"issue":"6","key":"779_CR13","doi-asserted-by":"publisher","first-page":"702","DOI":"10.20344\/amp.5905","volume":"28","author":"T Maricoto","year":"2015","unstructured":"Maricoto T, Rodrigues LV, Teixeira G, et al. Assessment of inhalation technique in clinical and functional control of asthma and chronic obstructive pulmonary disease. Acta Med Port. 2015;28(6):702\u20137.","journal-title":"Acta Med Port"},{"key":"779_CR14","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01794-2016","author":"M Molimard","year":"2017","unstructured":"Molimard M, Raherison C, Lignot S, et al. Chronic obstructive pulmonary disease exacerbation and inhaler device handling: real-life assessment of 2935 patients. Eur Respir J. 2017. https:\/\/doi.org\/10.1183\/13993003.01794-2016.","journal-title":"Eur Respir J"},{"issue":"1","key":"779_CR15","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1378\/chest.127.1.335","volume":"127","author":"MB Dolovich","year":"2005","unstructured":"Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes of aerosol therapy: evidence-based guidelines: American College of Chest Physicians\/American College of Asthma, Allergy, and Immunology. Chest. 2005;127(1):335\u201371. https:\/\/doi.org\/10.1378\/chest.127.1.335.","journal-title":"Chest"},{"issue":"1","key":"779_CR16","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1159\/000109374","volume":"75","author":"S Wieshammer","year":"2008","unstructured":"Wieshammer S, Dreyhaupt J. Dry powder inhalers: which factors determine the frequency of handling errors? Respir Int Rev Thorac Dis. 2008;75(1):18\u201325. https:\/\/doi.org\/10.1159\/000109374.","journal-title":"Respir Int Rev Thorac Dis"},{"issue":"8","key":"779_CR17","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1111\/j.1742-1241.2009.02060.x","volume":"63","author":"SC Allen","year":"2009","unstructured":"Allen SC, Warwick-Sanders M, Baxter M. A comparison of four tests of cognition as predictors of inability to learn to use a metered dose inhaler in old age. Int J Clin Pract. 2009;63(8):1150\u20133. https:\/\/doi.org\/10.1111\/j.1742-1241.2009.02060.x.","journal-title":"Int J Clin Pract"},{"issue":"5","key":"779_CR18","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1111\/j.1368-5031.2006.00933.x","volume":"60","author":"M Board","year":"2006","unstructured":"Board M, Allen SC. A simple drawing test to identify patients who are unlikely to be able to learn to use an inhaler. Int J Clin Pract. 2006;60(5):510\u20133. https:\/\/doi.org\/10.1111\/j.1368-5031.2006.00933.x.","journal-title":"Int J Clin Pract"},{"issue":"4","key":"779_CR19","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.rmed.2015.02.011","volume":"109","author":"Y Aydemir","year":"2015","unstructured":"Aydemir Y. Assessment of the factors affecting the failure to use inhaler devices before and after training. Respir Med. 2015;109(4):451\u20138. https:\/\/doi.org\/10.1016\/j.rmed.2015.02.011.","journal-title":"Respir Med"},{"issue":"1","key":"779_CR20","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/s12890-017-0386-6","volume":"17","author":"K Bartolo","year":"2017","unstructured":"Bartolo K, Balzan M, Schembri EL, et al. Predictors of correct technique in patients using pressurized metered dose inhalers. BMC Pulm Med. 2017;17(1):47. https:\/\/doi.org\/10.1186\/s12890-017-0386-6.","journal-title":"BMC Pulm Med"},{"issue":"2","key":"779_CR21","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.rehab.2009.11.001","volume":"53","author":"P Quinet","year":"2010","unstructured":"Quinet P, Young CA, Heritier F. The use of dry powder inhaler devices by elderly patients suffering from chronic obstructive pulmonary disease. Ann Phys Rehabil Med. 2010;53(2):69\u2013766. https:\/\/doi.org\/10.1016\/j.rehab.2009.11.001.","journal-title":"Ann Phys Rehabil Med"},{"issue":"9","key":"779_CR22","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1001\/archinte.1996.00440090084008","volume":"156","author":"SL Gray","year":"1996","unstructured":"Gray SL, Williams DM, Pulliam CC, et al. Characteristics predicting incorrect metered-dose inhaler technique in older subjects. Arch Intern Med. 1996;156(9):984\u20138.","journal-title":"Arch Intern Med"},{"issue":"3","key":"779_CR23","doi-asserted-by":"publisher","first-page":"367","DOI":"10.3109\/15412555.2015.1067675","volume":"13","author":"F Blasi","year":"2016","unstructured":"Blasi F, Canonica GW, Centanni S, et al. Genuair(R) usability test: results of a national public survey of the elderly. COPD. 2016;13(3):367\u201371. https:\/\/doi.org\/10.3109\/15412555.2015.1067675.","journal-title":"COPD"},{"issue":"4","key":"779_CR24","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1183\/09031936.00125109","volume":"35","author":"JW Dodd","year":"2010","unstructured":"Dodd JW, Getov SV, Jones PW. Cognitive function in COPD. Eur Respir J. 2010;35(4):913\u201322. https:\/\/doi.org\/10.1183\/09031936.00125109.","journal-title":"Eur Respir J"},{"issue":"6","key":"779_CR25","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1378\/chest.11-3035","volume":"142","author":"S Villeneuve","year":"2012","unstructured":"Villeneuve S, Pepin V, Rahayel S, et al. Mild cognitive impairment in moderate to severe COPD: a preliminary study. Chest. 2012;142(6):1516\u201323. https:\/\/doi.org\/10.1378\/chest.11-3035.","journal-title":"Chest"},{"issue":"2","key":"779_CR26","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1093\/ageing\/afl174","volume":"36","author":"S Jarvis","year":"2007","unstructured":"Jarvis S, Ind PW, Shiner RJ. Inhaled therapy in elderly COPD patients; time for re-evaluation? Age Ageing. 2007;36(2):213\u20138. https:\/\/doi.org\/10.1093\/ageing\/afl174.","journal-title":"Age Ageing"},{"key":"779_CR27","unstructured":"Vogelmeier C, Agusti A, Anzueo A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; 2020. p. 141. https:\/\/www.goldcopd.org. Accessed Feb 2020."},{"key":"779_CR28","unstructured":"Amaro F. Escala de Graffar, 1990."},{"key":"779_CR29","doi-asserted-by":"publisher","first-page":"65","DOI":"10.12707\/RIV14033","volume":"serIV","author":"JLA Ap\u00f3stolo","year":"2014","unstructured":"Ap\u00f3stolo JLA, Loureiro LMDJ, Reis IACD, et al. Contribui\u00e7\u00e3o para a adapta\u00e7\u00e3o da Geriatric Depression Scale-15 para a l\u00edngua portuguesa. Revista de Enfermagem Refer\u00eancia. 2014;serIV:65\u201373.","journal-title":"Revista de Enfermagem Refer\u00eancia"},{"key":"779_CR30","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1590\/S0034-8910.2015049005516","volume":"49","author":"DP Nunes","year":"2015","unstructured":"Nunes DP, Duarte YADO, Santos JLF, et al. Screening for frailty in older adults using a self-reported instrument. Rev Saude Publica. 2015;49:2. https:\/\/doi.org\/10.1590\/S0034-8910.2015049005516.","journal-title":"Rev Saude Publica"},{"issue":"3","key":"779_CR31","first-page":"345","volume":"9","author":"SSMR Freitas","year":"2010","unstructured":"Freitas SSMR, Cristina M, Vilar M, Santana I. Estudos de adapta\u00e7\u00e3o do Montreal Cognitive Assessment (MoCA) para a popula\u00e7\u00e3o portuguesa. Aval Psicol [online]. 2010;9(3):345\u201357.","journal-title":"Aval Psicol [online]"},{"issue":"2","key":"779_CR32","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1590\/S0034-89102012005000013","volume":"46","author":"AJ Ben","year":"2012","unstructured":"Ben AJ, Neumann CR, Mengue SS. The brief medication questionnaire and Morisky\u2013Green test to evaluate medication adherence. Rev Saude Publica. 2012;46(2):279\u201389.","journal-title":"Rev Saude Publica"},{"issue":"2","key":"779_CR33","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1590\/S1806-37132006000200006","volume":"32","author":"A Camelier","year":"2006","unstructured":"Camelier A, Rosa FW, Salim C, et al. Using the Saint George's Respiratory Questionnaire to evaluate quality of life in patients with chronic obstructive pulmonary disease: validating a new version for use in Brazil. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2006;32(2):114\u201322.","journal-title":"Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"issue":"4","key":"779_CR34","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/S0873-2159(15)30518-3","volume":"11","author":"J Ferreira","year":"2005","unstructured":"Ferreira J, Silveira P, Figueiredo MM, et al. Validation of the Portuguese version of the Asthma Quality of Life Questionnaire [AQLQ-M] by Marks. Revista portuguesa de pneumologia. 2005;11(4):351\u201366.","journal-title":"Revista portuguesa de pneumologia"},{"issue":"4","key":"779_CR35","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1590\/s1806-37132013000400002","volume":"39","author":"GP Silva","year":"2013","unstructured":"Silva GP, Morano MT, Viana CM, et al. Portuguese-language version of the COPD Assessment Test: validation for use in Brazil. Jornal brasileiro de pneumologia: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2013;39(4):402\u20138. https:\/\/doi.org\/10.1590\/s1806-37132013000400002.","journal-title":"Jornal brasileiro de pneumologia: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"issue":"12","key":"779_CR36","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1590\/S1806-37132008001200005","volume":"34","author":"D Kovelis","year":"2008","unstructured":"Kovelis D, Segretti NO, Probst VS, et al. Validation of the Modified pulmonary functional status and dyspnea questionnaire and the medical research council scale for use in Brazilian patients with chronic obstructive pulmonary disease. Jornal brasileiro de pneumologia: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2008;34(12):1008\u201318.","journal-title":"Jornal brasileiro de pneumologia: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"issue":"8","key":"779_CR37","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1111\/j.1398-9995.2009.02310.x","volume":"65","author":"JA Fonseca","year":"2010","unstructured":"Fonseca JA, Nogueira-Silva L, Morais-Almeida M, et al. Validation of a questionnaire (CARAT10) to assess rhinitis and asthma in patients with asthma. Allergy. 2010;65(8):1042\u20138. https:\/\/doi.org\/10.1111\/j.1398-9995.2009.02310.x.","journal-title":"Allergy"},{"issue":"2","key":"779_CR38","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1590\/S1806-37132010000200002","volume":"36","author":"JP Roxo","year":"2010","unstructured":"Roxo JP, Ponte EV, Ramos DC, et al. Portuguese-language version of the Asthma Control Test. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2010;36(2):159\u201366.","journal-title":"Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"issue":"1","key":"779_CR39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.7326\/M14-0697","volume":"162","author":"GS Collins","year":"2015","unstructured":"Collins GS, Reitsma JB, Altman DG, et al. Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (tripod): the tripod statement. Ann Intern Med. 2015;162(1):55\u201363. https:\/\/doi.org\/10.7326\/M14-0697.","journal-title":"Ann Intern Med"},{"key":"779_CR40","doi-asserted-by":"publisher","DOI":"10.1002\/0471722146","volume-title":"Applied logistic regression","author":"D Hosmer","year":"2000","unstructured":"Hosmer D, Lemeshow S. Applied logistic regression. 2nd ed. New York: Wiley; 2000.","edition":"2"},{"issue":"8","key":"779_CR41","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1164\/rccm.200508-1338PP","volume":"173","author":"S Suissa","year":"2006","unstructured":"Suissa S. Statistical treatment of exacerbations in therapeutic trials of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2006;173(8):842\u20136. https:\/\/doi.org\/10.1164\/rccm.200508-1338PP.","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"779_CR42","doi-asserted-by":"publisher","first-page":"250","DOI":"10.5694\/j.1326-5377.2005.tb06680.x","volume":"182","author":"VM McDonald","year":"2005","unstructured":"McDonald VM, Gibson PG. Inhalation-device polypharmacy in asthma. The Med J Aust. 2005;182(5):250\u20131.","journal-title":"The Med J Aust"},{"issue":"6","key":"779_CR43","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1177\/1060028015579097","volume":"49","author":"CA Sadowski","year":"2015","unstructured":"Sadowski CA, Cor K, Cave A, et al. Administration technique and acceptance of inhaler devices in patients with asthma or COPD. Ann Pharmacother. 2015;49(6):639\u201348. https:\/\/doi.org\/10.1177\/1060028015579097.","journal-title":"Ann Pharmacother"},{"issue":"3","key":"779_CR44","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s40268-013-0027-3","volume":"13","author":"G Galffy","year":"2013","unstructured":"Galffy G, Mezei G, Nemeth G, et al. Inhaler competence and patient satisfaction with Easyhaler(R): results of two real-life multicentre studies in asthma and COPD. Drugs R&D. 2013;13(3):215\u201322. https:\/\/doi.org\/10.1007\/s40268-013-0027-3.","journal-title":"Drugs R&D"},{"issue":"1","key":"779_CR45","doi-asserted-by":"publisher","first-page":"19","DOI":"10.4104\/pcrj.2012.00006","volume":"21","author":"H Pinnock","year":"2012","unstructured":"Pinnock H, Ostrem A, Rodriguez MR, et al. Prioritising the respiratory research needs of primary care: the International Primary Care Respiratory Group (IPCRG) e-Delphi exercise. Primary Care Respir J Gen Pract Airways Group. 2012;21(1):19\u201327. https:\/\/doi.org\/10.4104\/pcrj.2012.00006.","journal-title":"Primary Care Respir J Gen Pract Airways Group"},{"issue":"2","key":"779_CR46","doi-asserted-by":"publisher","first-page":"202","DOI":"10.3109\/02770900903581692","volume":"47","author":"M Takemura","year":"2010","unstructured":"Takemura M, Kobayashi M, Kimura K, et al. Repeated instruction on inhalation technique improves adherence to the therapeutic regimen in asthma. J Asthma Off J Assoc Care Asthma. 2010;47(2):202\u20138. https:\/\/doi.org\/10.3109\/02770900903581692.","journal-title":"J Asthma Off J Assoc Care Asthma"},{"key":"779_CR47","doi-asserted-by":"publisher","DOI":"10.1080\/02770903.2019.1582063","author":"E Freitas Ferreira","year":"2019","unstructured":"Freitas Ferreira E, Pascoal A, Silva P, et al. Inhaler training and asthma knowledge are associated with a higher proportion of patients with correct inhaler technique in young but not in elderly asthmatic patients. J Asthma. 2019. https:\/\/doi.org\/10.1080\/02770903.2019.1582063.","journal-title":"J Asthma"},{"key":"779_CR48","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15602","author":"T Maricoto","year":"2018","unstructured":"Maricoto T, Monteiro L, Gama JMR, et al. Inhaler technique education and exacerbation risk in older adults with asthma or chronic obstructive pulmonary disease: a meta-analysis. J Am Geriatr Soc. 2018. https:\/\/doi.org\/10.1111\/jgs.15602.","journal-title":"J Am Geriatr Soc"},{"key":"779_CR49","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.2147\/copd.s85681","volume":"10","author":"C Pothirat","year":"2015","unstructured":"Pothirat C, Chaiwong W, Phetsuk N, et al. Evaluating inhaler use technique in COPD patients. Int J Chronic Obstr Pulm Dis. 2015;10:1291\u20138. https:\/\/doi.org\/10.2147\/copd.s85681.","journal-title":"Int J Chronic Obstr Pulm Dis"},{"issue":"1","key":"779_CR50","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1590\/s1806-37132014000100003","volume":"40","author":"T Dalcin Pde","year":"2014","unstructured":"Dalcin Pde T, Grutcki DM, Laporte PP, et al. Factors related to the incorrect use of inhalers by asthma patients. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2014;40(1):13\u201320. https:\/\/doi.org\/10.1590\/s1806-37132014000100003.","journal-title":"Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"issue":"1","key":"779_CR51","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1177\/0897190015585759","volume":"30","author":"CR Beatty","year":"2017","unstructured":"Beatty CR, Flynn LA, Costello TJ. The impact of health literacy level on inhaler technique in patients with chronic obstructive pulmonary disease. J Pharm Pract. 2017;30(1):25\u201330. https:\/\/doi.org\/10.1177\/0897190015585759.","journal-title":"J Pharm Pract"},{"issue":"5","key":"779_CR52","doi-asserted-by":"publisher","first-page":"593","DOI":"10.4187\/respcare.04293","volume":"61","author":"A Alismail","year":"2016","unstructured":"Alismail A, Song CA, Terry MH, et al. Diverse inhaler devices: a big challenge for health-care professionals. Respir Care. 2016;61(5):593\u20139. https:\/\/doi.org\/10.4187\/respcare.04293.","journal-title":"Respir Care"},{"issue":"1","key":"779_CR53","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1590\/S1806-37132008000100003","volume":"34","author":"FP Muchao","year":"2008","unstructured":"Muchao FP, Perin SL, Rodrigues JC, et al. Evaluation of the knowledge of health professionals at a pediatric hospital regarding the use of metered-dose inhalers. Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia. 2008;34(1):4\u201312.","journal-title":"Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia"},{"issue":"9","key":"779_CR54","doi-asserted-by":"publisher","first-page":"982","DOI":"10.3109\/02770903.2014.928310","volume":"51","author":"B Gemicioglu","year":"2014","unstructured":"Gemicioglu B, Borekci S, Can G. Investigation of knowledge of asthma and inhaler devices in pharmacy workers. J Asthma Off J Assoc Care Asthma. 2014;51(9):982\u20138. https:\/\/doi.org\/10.3109\/02770903.2014.928310.","journal-title":"J Asthma Off J Assoc Care Asthma"},{"issue":"6","key":"779_CR55","doi-asserted-by":"publisher","first-page":"616","DOI":"10.3109\/02770903.2011.580032","volume":"48","author":"L Ovchinikova","year":"2011","unstructured":"Ovchinikova L, Smith L, Bosnic-Anticevich S. Inhaler technique maintenance: gaining an understanding from the patient's perspective. J Asthma Off J Assoc Care Asthma. 2011;48(6):616\u201324. https:\/\/doi.org\/10.3109\/02770903.2011.580032.","journal-title":"J Asthma Off J Assoc Care Asthma"},{"issue":"1","key":"779_CR56","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.anai.2016.05.002","volume":"117","author":"TH Self","year":"2016","unstructured":"Self TH, Hoth LM, Bolin JM, et al. Metered-dose inhaler technique per the global initiative for asthma and expert panel report 3. Ann Allergy Asthma Immunol. 2016;117(1):101\u20132. https:\/\/doi.org\/10.1016\/j.anai.2016.05.002.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"779_CR57","first-page":"9","volume":"25","author":"R Aguiar","year":"2017","unstructured":"Aguiar R, Lopes A, Ornelas C, et al. Terap\u00eautica inalat\u00f3ria: T\u00e9cnicas de inala\u00e7\u00e3o e dispositivos inalat\u00f3rios. Revista Portuguesa de Imunoalergologia. 2017;25:9\u201326.","journal-title":"Revista Portuguesa de Imunoalergologia"},{"key":"779_CR58","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.rmed.2016.04.016","volume":"115","author":"L Puente-Maestu","year":"2016","unstructured":"Puente-Maestu L, Calle M, Rodriguez-Hermosa JL, et al. Health literacy and health outcomes in chronic obstructive pulmonary disease. Respir Med. 2016;115:78\u201382. https:\/\/doi.org\/10.1016\/j.rmed.2016.04.016.","journal-title":"Respir Med"},{"key":"779_CR59","doi-asserted-by":"publisher","first-page":"14034","DOI":"10.1038\/npjpcrm.2014.34","volume":"24","author":"MA Crane","year":"2014","unstructured":"Crane MA, Jenkins CR, Goeman DP, et al. Inhaler device technique can be improved in older adults through tailored education: findings from a randomised controlled trial. NPJ Prim Care Respir Med. 2014;24:14034. https:\/\/doi.org\/10.1038\/npjpcrm.2014.34.","journal-title":"NPJ Prim Care Respir Med"},{"issue":"10","key":"779_CR60","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.1016\/j.rmed.2015.07.013","volume":"109","author":"C Bouwmeester","year":"2015","unstructured":"Bouwmeester C, Kraft J, Bungay KM. Optimizing inhaler use by pharmacist-provided education to community-dwelling elderly. Respir Med. 2015;109(10):1363\u20138. https:\/\/doi.org\/10.1016\/j.rmed.2015.07.013.","journal-title":"Respir Med"}],"container-title":["Drugs &amp; Aging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-020-00779-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s40266-020-00779-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s40266-020-00779-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T23:44:49Z","timestamp":1625010289000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s40266-020-00779-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,30]]},"references-count":60,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["779"],"URL":"https:\/\/doi.org\/10.1007\/s40266-020-00779-6","relation":{},"ISSN":["1170-229X","1179-1969"],"issn-type":[{"value":"1170-229X","type":"print"},{"value":"1179-1969","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,30]]},"assertion":[{"value":"30 June 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"There is no conflict of interests to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}}]}}