{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T10:26:13Z","timestamp":1793701573401,"version":"4.5.1"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"vor","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Deutschlandstipendium National Scholarship Program for Academic Excellence"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Eat Weight Disord"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Binge-eating disorder (BED) is common and often persistent despite evidence-based psychotherapy, highlighting the need for scalable adjunctive interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate feasibility, acceptability, and preliminary efficacy of a dietitian-supported ketogenic diet (KD) in adults with BED.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this 12-week, single-arm pilot study conducted at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, adults (18\u201365\u00a0years) with DSM-5 BED and BMI 25\u201345\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      received a structured KD (&lt;\u200920\u00a0g net carbohydrates\/day; 15\u201320% energy from protein; 70\u201380% from fat) with dietitian counseling. Capillary \u03b2-hydroxybutyrate (BHB) was self-monitored twice weekly to index nutritional ketosis (BHB\u2009\u2265\u20090.5\u00a0mmol\/L). Outcomes were assessed at baseline and week 12, including binge-eating days\/week (EDE), BED severity (Y-BOCS-BE), eating-disorder psychopathology (EDE-Q), depressive symptoms (PHQ-9), and body weight.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 39 individuals screened, 20 enrolled and 85% completed the 12-week assessment. Mean adherence (percent BHB readings\u2009\u2265\u20090.5\u00a0mmol\/L) was 76% (SD 14), with mean BHB 1.3\u00a0mmol\/L (SD 0.4). Binge-eating days\/week decreased from 4.2 (SD 1.3) to 1.1 (SD 1.5) (p\u2009&lt;\u20090.001). Y-BOCS-BE improved from 28.9 (SD 3.1) to 11.8 (SD 7.2) (p\u2009&lt;\u20090.001). EDE-Q decreased from 4.3 (SD 0.9) to 2.4 (SD 1.3) (p\u2009=\u20090.002), PHQ-9 from 16.5 (SD 3.8) to 8.2 (SD 4.5) (p\u2009=\u20090.005), and body weight from 102.4 (SD 16.1) kg to 95.8 (SD 16.9) kg (p\u2009&lt;\u20090.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this single-arm pilot study, a dietitian-supported ketogenic diet was feasible and acceptable in adults with BED, and improvements in binge-eating behaviors and related psychopathology were observed during the 12-week intervention period. These findings are preliminary and do not establish therapeutic efficacy. Controlled trials with active comparators and longer follow-up are required to evaluate safety, sustainability, and clinical utility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s40519-026-01843-7","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:28:30Z","timestamp":1774520910000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A ketogenic diet for the management of binge-eating disorder: a pilot study"],"prefix":"10.1007","volume":"31","author":[{"given":"Yixuan","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"Haas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuyu","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"issue":"3","key":"1843_CR1","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.biopsych.2006.03.040","volume":"61","author":"JI Hudson","year":"2007","unstructured":"Hudson JI, Hiripi E, Pope HG Jr, Kessler RC (2007) The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. 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