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One hundred and two older adults aged 78.0\u2009\u00b1\u20098.4\u00a0years, predominantly female (67.6%), with neurocognitive disorder due to Alzheimer\u2019s disease (AD) (49.2%), vascular dementia (14.7%), Parkinson\u2019s disease (2%), dementia with Lewy bodies (2%) or unspecified dementia (32.1%) participated in the present study. Regression analyses were used to examine associations between physical fitness components (Senior Fitness Test) and cognitive function (Mini-Mental State Examination), functional capacity (Katz Index of Independence in Activities of Daily Living) and Quality of Life (QoL)-Alzheimer's Disease scale. Univariate regression indicates that strength, flexibility, agility\/dynamic balance and aerobic endurance are relevant for cognitive function, physical capacity and perceived QoL in institutionalized older people with dementia. After multiple regression analyses, adjusted for body mass index (BMI), results showed that aerobic endurance had a significant positive association with Total Katz Index. For both, caregiver perception of QoL-AD and global QoL-AD, BMI remained significantly and positively associated. Agility\u2013dynamic balance presented a significant negative relation with global QoL-AD. Overall, our findings suggest that better physical fitness is important for cognition and autonomous functional capacity and that it has positive repercussions on the QoL in institutionalized older adults with dementia. Consequently, exercise-based therapeutic strategies aiming to improve physical fitness should be implemented.<\/jats:p>","DOI":"10.1007\/s40520-019-01445-7","type":"journal-article","created":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T17:02:40Z","timestamp":1578762160000},"page":"2329-2338","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Physical fitness in institutionalized older adults with dementia: association with cognition, functional capacity and quality of life"],"prefix":"10.1007","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3644-2946","authenticated-orcid":false,"given":"A.","family":"Sampaio","sequence":"first","affiliation":[]},{"given":"I.","family":"Marques-Aleixo","sequence":"additional","affiliation":[]},{"given":"A.","family":"Seabra","sequence":"additional","affiliation":[]},{"given":"J.","family":"Mota","sequence":"additional","affiliation":[]},{"given":"E.","family":"Marques","sequence":"additional","affiliation":[]},{"given":"J.","family":"Carvalho","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2020,1,11]]},"reference":[{"key":"1445_CR1","first-page":"1450","volume":"13","author":"T Dua","year":"2017","unstructured":"Dua T et al (2017) World Health Organization\u00b4s Global Action Plan on the Response to Dementia 2017-2025. 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The study protocol was accepted by the Ethical Commission of the Faculty of Sports of the University of Porto (Ref CEFADE02.2014).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from the patients or substitute decision-makers if the patients did not have the capacity to consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}