{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T05:35:22Z","timestamp":1773984922957,"version":"3.50.1"},"reference-count":56,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["UIDB\/00690\/2020; UIDP\/00690\/2020; LA\/P\/0007\/2021; UIDB\/50006\/2020; UIDB\/04033\/2020; UIDP\/50006\/2020"],"award-info":[{"award-number":["UIDB\/00690\/2020; UIDP\/00690\/2020; LA\/P\/0007\/2021; UIDB\/50006\/2020; UIDB\/04033\/2020; UIDP\/50006\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2020.01614.CEECIND\/CP1596\/CT0007"],"award-info":[{"award-number":["2020.01614.CEECIND\/CP1596\/CT0007"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2021.07764.BD"],"award-info":[{"award-number":["2021.07764.BD"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["2021.08361.BD"],"award-info":[{"award-number":["2021.08361.BD"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"crossref","award":["Project BeeLand 10\/C05-i03\/2021.PPRR-C05-i03-I-000081"],"award-info":[{"award-number":["Project BeeLand 10\/C05-i03\/2021.PPRR-C05-i03-I-000081"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["emergent mater."],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>The outer layer of the pollen grain, which plays a crucial role in the continuity of terrestrial plant life, has received significant attention due to its robustness, chemical inertness, and biocompatible structure made of sporopollenin. Herein, we present a straightforward method for producing high-purity (up to 97%) polymeric sporopollenin biocapsules (S-BioCaps) from bee pollen, exploring new plant sources for S-BioCaps, and diversifying the available morphologies to broaden the applications of pollen-based microcapsules. Following a purification process involving defatting, acidolysis, and several washing steps, we removed the inner components of the pollen grains and reduced the protein content to 2%. Confocal laser scanning and scanning electron microscopy images showed that the hollow and 3D S-BioCaps microstructure were preserved, while laser diffraction particle size analysis validated their monodisperse distribution across each pollen type within the size range of 15 to 24\u00a0\u03bcm. S-BioCaps tended to exhibit hydrophobic behavior when assessed through water dispersion and water marble analysis. Moreover, we sought to figure out the chemical changes occurring in specimens through Fourier-transform infrared analysis, and findings were consistent with simultaneous thermal analysis, where the thermal decomposition of sporopollenin biopolymer reached up to 457\u00a0\u00b0C. Overall, this work demonstrates a straightforward approach for utilizing pollen grains from <jats:italic>Echium<\/jats:italic> sp., <jats:italic>Jasione<\/jats:italic> sp., <jats:italic>Papaver<\/jats:italic> sp., Amaranthaceae, and <jats:italic>Helianthemum<\/jats:italic> sp., collected with the assistance of honeybees, to produce stable S-BioCaps with diverse morphologies, thereby broadening their potential applications as drug delivery microcarriers.<\/jats:p>\n          <jats:p>\n            <jats:bold>Graphical abstract<\/jats:bold>\n          <\/jats:p>","DOI":"10.1007\/s42247-025-01002-1","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T06:16:44Z","timestamp":1737958604000},"page":"3107-3122","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Development of natural sporopollenin microcapsules: from bee pollen to versatile biomaterials"],"prefix":"10.1007","volume":"8","author":[{"given":"Volkan","family":"Aylanc","sequence":"first","affiliation":[]},{"given":"Seymanur","family":"Ertosun","sequence":"additional","affiliation":[]},{"given":"Andreia F.","family":"Peixoto","sequence":"additional","affiliation":[]},{"given":"Arantzazu","family":"Santamaria-Echart","sequence":"additional","affiliation":[]},{"given":"Paulo","family":"Russo-Almeida","sequence":"additional","affiliation":[]},{"given":"Nuno","family":"Vale","sequence":"additional","affiliation":[]},{"given":"Cristina","family":"Freire","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8665-5280","authenticated-orcid":false,"given":"Miguel","family":"Vilas-Boas","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2025,1,27]]},"reference":[{"key":"1002_CR1","doi-asserted-by":"publisher","DOI":"10.1039\/C9SM01634A","author":"MG Bah","year":"2020","unstructured":"M.G. Bah, H.M. Bilal, J. Wang, Soft Matter. (2020). https:\/\/doi.org\/10.1039\/C9SM01634A","journal-title":"Soft Matter"},{"key":"1002_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmt.2023.101860","author":"V Aylanc","year":"2023","unstructured":"V. Aylanc, A.F. Peixoto, N. Vale, C. Freire, M. Vilas-Boas, Appl. Mater. Today. (2023). https:\/\/doi.org\/10.1016\/j.apmt.2023.101860","journal-title":"Appl. Mater. Today"},{"key":"1002_CR3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-chembioeng-101121-085959","author":"C Zhou","year":"2024","unstructured":"C. Zhou, J. Deng, J.H. Tay, S. Basu, J. Yang, J. Li, C. Yang, Z. Zhao, N.J. Cho, Annu. Rev. Chem. Biomol. Eng. (2024). https:\/\/doi.org\/10.1146\/annurev-chembioeng-101121-085959","journal-title":"Annu. Rev. Chem. Biomol. Eng."},{"key":"1002_CR4","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202000602","author":"H Huang","year":"2020","unstructured":"H. Huang, T. Shi, R. He, J. Wang, P.K. Chu, X.-F. Yu, H. Huang, T. Shi, R. He, J. Wang, X. Yu, P.K. Chu, Adv. Sci. (2020). https:\/\/doi.org\/10.1002\/advs.202000602","journal-title":"Adv. Sci."},{"key":"1002_CR5","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-77780-1","author":"W Malik","year":"2024","unstructured":"W. Malik, J.P.V. Tafoya, S. Doszczeczko, A.B.J. Sobrido, A.N. Boa, R. Volpe, Sci. Rep. (2024). https:\/\/doi.org\/10.1038\/s41598-024-77780-1","journal-title":"Sci. Rep."},{"key":"1002_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.133051","author":"Y Yang","year":"2024","unstructured":"Y. Yang, W. Zhang, L. Zhang, M. Guo, C. Xiang, M. Ren, Y. Han, J. Shi, H. Li, X. Xu, Int. J. Biol. Macromol. (2024). https:\/\/doi.org\/10.1016\/j.ijbiomac.2024.133051","journal-title":"Int. J. Biol. Macromol."},{"key":"1002_CR7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cofs.2022.100809","author":"PJ Schouten","year":"2022","unstructured":"P.J. Schouten, D. Soto-Aguilar, A. Aldalbahi, T. Ahamad, S. Alzahly, V. Fogliano, Curr. Opin. Food Sci. (2022). https:\/\/doi.org\/10.1016\/j.cofs.2022.100809","journal-title":"Curr. Opin. Food Sci."},{"key":"1002_CR8","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202316510","author":"H Jiang","year":"2024","unstructured":"H. Jiang, H. Yu, X. Guan, W. Jiang, Y. Li, W. Liu, C. Yang, J. Jiang, B.P. Binks, T. Ngai, Adv. Funct. Mater. (2024). https:\/\/doi.org\/10.1002\/adfm.202316510","journal-title":"Adv. Funct. Mater."},{"key":"1002_CR9","doi-asserted-by":"publisher","unstructured":"S. Liu, S.Y. Quek, K. Huang, Small. (2024). https:\/\/doi.org\/10.1002\/smll.202403465","DOI":"10.1002\/smll.202403465"},{"key":"1002_CR10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-24336-9","author":"T Fan","year":"2018","unstructured":"T. Fan, J.H. Park, Q.A. Pham, E.L. Tan, R.C. Mundargi, M.G. Potroz, H. Jung, N.J. Cho, Sci. Rep. (2018). https:\/\/doi.org\/10.1038\/s41598-018-24336-9","journal-title":"Sci. Rep."},{"key":"1002_CR11","doi-asserted-by":"publisher","DOI":"10.1039\/C9NJ05082E","author":"CS Pomelli","year":"2020","unstructured":"C.S. Pomelli, F. D\u2019Andrea, A. Mezzetta, L. Guazzelli, New. J. Chem. (2020). https:\/\/doi.org\/10.1039\/C9NJ05082E","journal-title":"New. J. Chem."},{"key":"1002_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2021.01.042","author":"V Aylanc","year":"2021","unstructured":"V. Aylanc, S.I. Falc\u00e3o, S. Ertosun, M. Vilas-Boas, Trends Food Sci. Technol. (2021). https:\/\/doi.org\/10.1016\/j.tifs.2021.01.042","journal-title":"Trends Food Sci. Technol."},{"key":"1002_CR13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-46131-w","author":"TF Fan","year":"2019","unstructured":"T.F. Fan, M.G. Potroz, E.L. Tan, M.S. Ibrahim, E. Miyako, N.J. Cho, Sci. Rep. (2019). https:\/\/doi.org\/10.1038\/s41598-019-46131-w","journal-title":"Sci. Rep."},{"key":"1002_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/J.APMT.2019.100525","author":"EL Tan","year":"2020","unstructured":"E.L. Tan, M.G. Potroz, G. Ferracci, L. Wang, J.A. Jackman, N.J. Cho, Appl. Mater. Today. (2020). https:\/\/doi.org\/10.1016\/J.APMT.2019.100525","journal-title":"Appl. Mater. Today"},{"key":"1002_CR15","doi-asserted-by":"publisher","unstructured":"M. Raish, M.A. Kalam, A. Ahmad, M. Shahid, M.A. Ansari, A. Ahad, R. Ali, Y.A.B. Jardan, A. Alshamsan, M. Alkholief, K.M. Alkharfy, I.A. Abdelrahman, F.I. Al-Jenoobi, Pharmaceutics. (2021). https:\/\/doi.org\/10.3390\/pharmaceutics13111921","DOI":"10.3390\/pharmaceutics13111921"},{"key":"1002_CR16","doi-asserted-by":"publisher","DOI":"10.1039\/D2RA02888C","author":"ASY Mohammed","year":"2022","unstructured":"A.S.Y. Mohammed, A.K.F. Dyab, F. Taha, I Abd El-Mageed RSC Adv. (2022). https:\/\/doi.org\/10.1039\/D2RA02888C","journal-title":"I Abd El-Mageed RSC Adv."},{"key":"1002_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2022.103278","author":"NF Taha","year":"2022","unstructured":"N.F. Taha, A.K.F. Dyab, L.H. Emara, N.M. Meligi, J. Drug Deliv Sci. Technol. (2022). https:\/\/doi.org\/10.1016\/j.jddst.2022.103278","journal-title":"J. Drug Deliv Sci. Technol."},{"key":"1002_CR18","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.2c00071","author":"FE Atalay","year":"2022","unstructured":"F.E. Atalay, A.A. Culum, H. Kaya, G. Gokturk, E. Yigit, ACS Appl. Bio Mater. (2022). https:\/\/doi.org\/10.1021\/acsabm.2c00071","journal-title":"ACS Appl. Bio Mater."},{"key":"1002_CR19","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1132129","author":"J Liu","year":"2023","unstructured":"J. Liu, X.D. Yan, X.Q. Li, Y.H. Du, L.L. Zhu, T.T. Ye, Z.Y. Cao, Z.W. Dong, S.T. Li, X. Xu, W. Bai, D. Li, J.W. Zhang, S.J. Wang, S.H. Li, J. Sun, X.Z. Yin, Front. Immunol. (2023). https:\/\/doi.org\/10.3389\/fimmu.2023.1132129","journal-title":"Front. Immunol."},{"key":"1002_CR20","doi-asserted-by":"publisher","unstructured":"K. Stamatopoulos, V. Kafourou, H.K. Batchelor, S.J. Konteles, Small. (2021). https:\/\/doi.org\/10.1002\/smll.202004573","DOI":"10.1002\/smll.202004573"},{"key":"1002_CR21","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.7b03228","author":"X Jiang","year":"2018","unstructured":"X. Jiang, Y. Liu, H. Hao, Y. Xu, J. Huang, D. Sun, Q. Li, ACS Sustain. Chem. Eng. (2018). https:\/\/doi.org\/10.1021\/acssuschemeng.7b03228","journal-title":"ACS Sustain. Chem. Eng."},{"key":"1002_CR22","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202313808","author":"J Kim","year":"2024","unstructured":"J. Kim, J. Deng, N.J. Cho, S.M. Han, Adv. Funct. Mater. (2024). https:\/\/doi.org\/10.1002\/adfm.202313808","journal-title":"Adv. Funct. Mater."},{"key":"1002_CR23","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202106276","author":"S Chen","year":"2021","unstructured":"S. Chen, Q. Shi, T. Jang, M.S. Bin Ibrahim, J. Deng, G. Ferracci, W.S. Tan, N.J. Cho, J. Song, Adv. Funct. Mater. (2021). https:\/\/doi.org\/10.1002\/adfm.202106276","journal-title":"Adv. Funct. Mater."},{"key":"1002_CR24","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-87619-8","author":"K Heged\u00fcs","year":"2021","unstructured":"K. Heged\u00fcs, C. Feh\u00e9r, I. Jalsovszky, Z. Krist\u00f3f, J. Rohonczy, E. Vass, A. Farkas, T. Csizmadia, G. Friedbacher, P. Hantz, Sci. Rep. (2021). https:\/\/doi.org\/10.1038\/s41598-021-87619-8","journal-title":"Sci. Rep."},{"key":"1002_CR25","doi-asserted-by":"publisher","DOI":"10.1093\/jee\/toy125","author":"SE Hoover","year":"2018","unstructured":"S.E. Hoover, L.P. Ovinge, J. Econ. Entomol. (2018). https:\/\/doi.org\/10.1093\/jee\/toy125","journal-title":"J. Econ. Entomol."},{"key":"1002_CR26","doi-asserted-by":"publisher","DOI":"10.1111\/conl.12263","author":"JH Cane","year":"2017","unstructured":"J.H. Cane, V.J. Tepedino, Conserv. Lett. (2017). https:\/\/doi.org\/10.1111\/conl.12263","journal-title":"Conserv. Lett."},{"key":"1002_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2018.09.008","author":"QQ Li","year":"2018","unstructured":"Q.Q. Li, K. Wang, M.C. Marcucci, A.C.H.F. Sawaya, L. Hu, X.F. Xue, L.M. Wu, F.L. Hu, J. Funct. Foods. (2018). https:\/\/doi.org\/10.1016\/j.jff.2018.09.008","journal-title":"J. Funct. Foods"},{"key":"1002_CR28","doi-asserted-by":"publisher","unstructured":"J. Louveaux, A. Maurizio, G. Vorwohl, Bee World. (1978). https:\/\/doi.org\/10.1080\/0005772X.1978.11097714","DOI":"10.1080\/0005772X.1978.11097714"},{"key":"1002_CR29","doi-asserted-by":"publisher","unstructured":"W. Von Der Ohe, L. Persano Oddo, M.L. Piana, M. Morlot, P. Martin, Apidologie. (2004). https:\/\/doi.org\/10.1051\/apido:2004050","DOI":"10.1051\/apido:2004050"},{"key":"1002_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmt.2020.100594","author":"TF Fan","year":"2020","unstructured":"T.F. Fan, Y. Hwang, M.G. Potroz, K.L. Lau, E.L. Tan, M. Shahrudin Ibrahim, E. Miyako, N.J. Cho, Appl. Mater. Today. (2020). https:\/\/doi.org\/10.1016\/j.apmt.2020.100594","journal-title":"Appl. Mater. Today"},{"key":"1002_CR31","volume-title":"Official Methods of Analysis of AOAC INTERNATIONAL","author":"AOAC","year":"2016","unstructured":"AOAC, Official Methods of Analysis of AOAC INTERNATIONAL, 20th edn. (AOAC International, Gaithersburg, 2016)","edition":"20"},{"key":"1002_CR32","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2021.108262","author":"AS de Carvalho","year":"2021","unstructured":"A.S. de Carvalho, S.C. de Rezende, C. Caleja, E. Pereira, L. Barros, I. Fernandes, Y.A. Manrique, O.H. Gon\u00e7alves, I.C.F.R. Ferreira, M.F. Barreiro, Food Control. (2021). https:\/\/doi.org\/10.1016\/j.foodcont.2021.108262","journal-title":"Food Control"},{"key":"1002_CR33","doi-asserted-by":"publisher","DOI":"10.1039\/C0SM01516D","author":"BP Binks","year":"2011","unstructured":"B.P. Binks, A.N. Boa, M.A. Kibble, G. MacKenzie, A. Rocher, Soft Matter. (2011). https:\/\/doi.org\/10.1039\/C0SM01516D","journal-title":"Soft Matter"},{"key":"1002_CR34","doi-asserted-by":"publisher","DOI":"10.1038\/35082026","author":"P Aussillous","year":"2001","unstructured":"P. Aussillous, D. Qu\u00e9r\u00e9, Nature. (2001). https:\/\/doi.org\/10.1038\/35082026","journal-title":"Nature"},{"key":"1002_CR35","doi-asserted-by":"publisher","unstructured":"R. Bleha, T.V. Shevtsova, M. \u017div\u010d\u00e1kov\u00e1, A. Korb\u00e1\u0159ov\u00e1, M. Je\u017ekov\u00e1, I. Salo\u0148, J. Brindza, A. Synytsya, Foods. (2021). https:\/\/doi.org\/10.3390\/foods10081682","DOI":"10.3390\/foods10081682"},{"key":"1002_CR36","doi-asserted-by":"publisher","DOI":"10.3897\/jhr.71.32671","author":"ZM Portman","year":"2019","unstructured":"Z.M. Portman, M.C. Orr, T. Griswold, J. Hymenopt Res. (2019). https:\/\/doi.org\/10.3897\/jhr.71.32671","journal-title":"J. Hymenopt Res."},{"key":"1002_CR37","doi-asserted-by":"publisher","DOI":"10.1007\/BF00176173","author":"JH Fewell","year":"1992","unstructured":"J.H. Fewell, M.L. Winston, Behav. Ecol. Sociobiol. (1992). https:\/\/doi.org\/10.1007\/BF00176173","journal-title":"Behav. Ecol. Sociobiol."},{"key":"1002_CR38","doi-asserted-by":"publisher","DOI":"10.1093\/ee\/14.6.683","author":"TC Webster","year":"1985","unstructured":"T.C. Webster, R.W. Thorp, D. Briggs, J. Skinner, T. Parisian, Environ. Entomol. (1985). https:\/\/doi.org\/10.1093\/ee\/14.6.683","journal-title":"Environ. Entomol."},{"key":"1002_CR39","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b03040","author":"MJ Uddin","year":"2019","unstructured":"M.J. Uddin, N. Abidi, J. Warzywoda, H.S. Gill, ACS Appl. Mater. Interfaces. (2019). https:\/\/doi.org\/10.1021\/acsami.9b03040","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"1002_CR40","doi-asserted-by":"publisher","DOI":"10.1038\/srep28017","author":"JH Park","year":"2016","unstructured":"J.H. Park, J. Seo, J.A. Jackman, N.J. Cho, Sci. Rep. (2016). https:\/\/doi.org\/10.1038\/srep28017","journal-title":"Sci. Rep."},{"key":"1002_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.10.019","author":"MJ Uddin","year":"2017","unstructured":"M.J. Uddin, H.S. Gill, J. Control Release. (2017). https:\/\/doi.org\/10.1016\/j.jconrel.2017.10.019","journal-title":"J. Control Release"},{"key":"1002_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2018.10.016","author":"SV Lale","year":"2018","unstructured":"S.V. Lale, H.S. Gill, Int. J. Pharm. (2018). https:\/\/doi.org\/10.1016\/j.ijpharm.2018.10.016","journal-title":"Int. J. Pharm."},{"key":"1002_CR43","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA27207F","author":"RC Mundargi","year":"2016","unstructured":"R.C. Mundargi, M.G. Potroz, J.H. Park, J. Seo, J.H. Lee, N.J. Cho, RSC Adv. (2016). https:\/\/doi.org\/10.1039\/C5RA27207F","journal-title":"RSC Adv."},{"key":"1002_CR44","doi-asserted-by":"publisher","unstructured":"M.J. Uddin, S. Liyanage, J. Warzywoda, N. Abidi, H.S. Gill, Langmuir. (2022). https:\/\/doi.org\/10.1021\/acs.langmuir.1c02682","DOI":"10.1021\/acs.langmuir.1c02682"},{"key":"1002_CR45","doi-asserted-by":"publisher","unstructured":"A. Lutzke, K.J. Morey, J.I. Medford, M.J. Kipper, Phytochemistry. (2020) https:\/\/doi.org\/10.1016\/j.phytochem.2019.112195","DOI":"10.1016\/j.phytochem.2019.112195"},{"key":"1002_CR46","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.8b00304","author":"P Gonzalez-Cruz","year":"2018","unstructured":"P. Gonzalez-Cruz, M.J. Uddin, S.U. Atwe, N. Abidi, H.S. Gill, ACS Biomater. Sci. Eng. (2018). https:\/\/doi.org\/10.1021\/acsbiomaterials.8b00304","journal-title":"ACS Biomater. Sci. Eng."},{"key":"1002_CR47","doi-asserted-by":"publisher","DOI":"10.1104\/pp.104.050773","author":"E Parre","year":"2005","unstructured":"E. Parre, A. Geitmann, Plant. Physiol. (2005). https:\/\/doi.org\/10.1104\/pp.104.050773","journal-title":"Plant. Physiol."},{"key":"1002_CR48","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c07301","author":"E Alpizar-Reyes","year":"2022","unstructured":"E. Alpizar-Reyes, J.L. Concha, F.J. Mart\u00edn-Mart\u00ednez, J. Norambuena-Contreras, ACS Appl. Mater. Interfaces. (2022). https:\/\/doi.org\/10.1021\/acsami.2c07301","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"1002_CR49","doi-asserted-by":"publisher","DOI":"10.5194\/amt-6-3369-2013","author":"C P\u00f6hlker","year":"2013","unstructured":"C. P\u00f6hlker, J.A. Huffman, U. P\u00f6schl, Atmos. Meas. Tech. (2013). https:\/\/doi.org\/10.5194\/amt-6-3369-2013","journal-title":"Atmos. Meas. Tech."},{"key":"1002_CR50","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201700270","author":"MG Potroz","year":"2017","unstructured":"M.G. Potroz, R.C. Mundargi, J.J. Gillissen, E.L. Tan, S. Meker, J.H. Park, H. Jung, S. Park, D. Cho, S.I. Bang, N.J. Cho, Adv. Funct. Mater. (2017). https:\/\/doi.org\/10.1002\/adfm.201700270","journal-title":"Adv. Funct. Mater."},{"key":"1002_CR51","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2018.07.028","author":"MJ Uddin","year":"2018","unstructured":"M.J. Uddin, S. Liyanage, N. Abidi, H.S. Gill, J. Pharm. Sci. (2018). https:\/\/doi.org\/10.1016\/j.xphs.2018.07.028","journal-title":"J. Pharm. Sci."},{"key":"1002_CR52","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-68875-6","author":"C Chiappe","year":"2020","unstructured":"C. Chiappe, M.J. Rodriguez-Douton, M.C. Mozzati, D. Prete, A. Griesi, L. Guazzelli, M. Gemmi, S. Caporali, N. Calisi, C.S. Pomelli, F. Rossella, Sci. Rep. (2020). https:\/\/doi.org\/10.1038\/s41598-020-68875-6","journal-title":"Sci. Rep."},{"key":"1002_CR53","doi-asserted-by":"publisher","DOI":"10.1038\/s41477-018-0330-7","author":"FS Li","year":"2018","unstructured":"F.S. Li, P. Phyo, J. Jacobowitz, M. Hong, J.K. Weng, Nat. Plants. (2018). https:\/\/doi.org\/10.1038\/s41477-018-0330-7","journal-title":"Nat. Plants"},{"key":"1002_CR54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.08.017","author":"A Diego-Taboada","year":"2022","unstructured":"A. Diego-Taboada, T. Sathyapalan, F. Courts, M. Lorch, F. Almutairi, B.P. Burke, K. Harris, M. Kruusm\u00e4gi, T. Walther, J. Booth, A.N. Boa, S.J. Archibald, C. Thompson, S.L. Atkin, G. Mackenzie, J. Control Release. (2022). https:\/\/doi.org\/10.1016\/j.jconrel.2022.08.017","journal-title":"J. Control Release"},{"key":"1002_CR55","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.145184","author":"D Li","year":"2023","unstructured":"D. Li, L. Sun, L. Shi, L. Zhuo, L. Yang, J. Zhang, Y. Han, T. Ye, S. Wang, Chem. Eng. J. (2023). https:\/\/doi.org\/10.1016\/j.cej.2023.145184","journal-title":"Chem. Eng. J."},{"key":"1002_CR56","doi-asserted-by":"publisher","unstructured":"S. Bernard, K. Benzerara, O. Beyssac, E. Balan, G.E. Brown, Heliyon (2015). https:\/\/doi.org\/10.1016\/j.heliyon.2015.e00034","DOI":"10.1016\/j.heliyon.2015.e00034"}],"container-title":["Emergent Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42247-025-01002-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s42247-025-01002-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s42247-025-01002-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T11:49:11Z","timestamp":1759319351000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s42247-025-01002-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,27]]},"references-count":56,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["1002"],"URL":"https:\/\/doi.org\/10.1007\/s42247-025-01002-1","relation":{},"ISSN":["2522-5731","2522-574X"],"issn-type":[{"value":"2522-5731","type":"print"},{"value":"2522-574X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,27]]},"assertion":[{"value":"15 November 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}]}}