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Whatever the stage of development, anti\u2010MAP\u20102 serum detected high molecular mass proteins and at immature stages a protein of 62 kDa. This protein which has previously been referred to as \u2018young TAU slow\u2019 is, therefore, immunologically related to MAP\u20102. The anti\u2010TAU serum (but not the anti\u2010MAP\u20102 serum) detected at immature stages of development a 48 kDa protein which also disappears at adulthood. This 48 kDa entity which has been referred to as \u2018young TAU fast\u2019 is progressively replaced by the closely spaced bands (60\u201370 kDa) of adult TAU proteins. The 62 and 48 kDa proteins appear therefore to be immunologically distinct and represent two microtubule\u2010associated proteins specific to the immature brain.<\/jats:p>","DOI":"10.1016\/0014-5793(85)80397-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T07:58:50Z","timestamp":1027583930000},"page":"331-335","source":"Crossref","is-referenced-by-count":63,"title":["Immunological characterization of microtubule\u2010associated proteins specific for the immature brain"],"prefix":"10.1002","volume":"188","author":[{"given":"D.","family":"Couchie","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Nunez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,2,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00631a004"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.72.1.177"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(77)90213-3"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.17.5613"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/284353a0"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1982.tb07072.x"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.79.16.4892"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.98.3.1090"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.70.3.765"},{"key":"e_1_2_1_11_1","first-page":"167","volume":"78","author":"Fellous A.","year":"1977","journal-title":"J. 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