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Moreover, 22 out of 24 amino acid residues are identical around the predicted active site. It is therefore suggested that these two kinds \u03b2\u2010lactamases share a common evolutionary origin. The 0.5 kb DNA fragment of the cloned gene hybridized specifically with the chromosomal DNA of all the <jats:italic>K<\/jats:italic>. <jats:italic>pneumoniae<\/jats:italic> strains tested which had been isolated in Japan, USA and Europe.<\/jats:p>","DOI":"10.1016\/0014-5793(86)80014-x","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T07:57:40Z","timestamp":1027583860000},"page":"69-74","source":"Crossref","is-referenced-by-count":66,"title":["Close evolutionary relationship between the chromosomally encoded \u03b2 lactamase gene of <i>Klebsiella<\/i><i>pneumoniae<\/i> and the TEM \u03b2\u2010lactamase gene mediated by R plasmids"],"prefix":"10.1002","volume":"207","author":[{"given":"Yoshichika","family":"Arakawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michio","family":"Ohta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Kido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuaki","family":"Fujii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Komatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Kato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,11,12]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.122.1.250-256.1975"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1980.0049"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/145.2.762"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(79)90228-9"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1972.tb00645.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.115.3.1045-1054.1973"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1981.tb00098.x"},{"key":"e_1_2_1_9_1","volume-title":"Molecular Cloning","author":"Maniatis T.","year":"1982"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(81)90148-7"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(80)90259-7"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.8.3732"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.8.3737"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2340343"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.8.4897"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.164.1.456-460.1985"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/11.14.4997"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1510197"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1949.tb00741.x"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/91.1.92"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1951.tb03697.x"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/94.1.65"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793%2886%2980014-X","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793(86)80014-X","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/0014-5793%2886%2980014-X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T19:38:49Z","timestamp":1694893129000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1016\/0014-5793%2886%2980014-X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,10,20]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1986,10,20]]}},"alternative-id":["10.1016\/0014-5793(86)80014-X"],"URL":"https:\/\/doi.org\/10.1016\/0014-5793(86)80014-x","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,10,20]]}}}