{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T11:15:57Z","timestamp":1772795757691,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"1-2","license":[{"start":{"date-parts":[[2002,1,16]],"date-time":"2002-01-16T00:00:00Z","timestamp":1011139200000},"content-version":"vor","delay-in-days":3803,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[1991,8,19]]},"abstract":"<jats:p>The <jats:italic>Xenopus<\/jats:italic> polymerase I transcription factor xUBF is an HMG\u2010box protein which has been purified as two polypeptides of \u223c82 and 85 kDa. Recently a cDNA sequence predicted an xUBF protein (xUBF1) of 677 amino acids (79 kDa) containing five tandem HMG\u2010boxes. Here a second and distinct xUBF cDNA has been isolated and characterised. This cDNA codes an xUBF protein (xUBF2) of 701 amino acids (82 kDa), having 93% homology with xUBF1 but containing an insertion of 22 amino acids between HMG\u2010boxes 3 and 4. In vitro translation of synthetic mRNAs derived from the xUBF1 and 2 cDNAs was used to show that the electrophoretic mobility of the gene products accounted for the major xUBF molecular weight heterogeneity noted in vivo. It is also shown that the <jats:italic>Xenopus laevis<\/jats:italic> genome contains 3 or 4 distinct loci which hybridise with xUBF coding sequences, leaving open the possibility of yet further unrecognised heterogeneity in xUBF.<\/jats:p>","DOI":"10.1016\/0014-5793(91)81002-p","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T07:43:20Z","timestamp":1027583000000},"page":"55-59","source":"Crossref","is-referenced-by-count":8,"title":["Heterogeneity in the <i>Xenopus<\/i> ribosomal transcription factor xUBF has a molecular basis distinct from that in mammals"],"prefix":"10.1002","volume":"288","author":[{"given":"Dimcho","family":"Bachvarov","sequence":"first","affiliation":[]},{"given":"Marc","family":"Normandeau","sequence":"additional","affiliation":[]},{"given":"Tom","family":"Moss","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2002,1,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3413483"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.4.6.943"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.10.7.3810"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/344830a0"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.8.3180"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.3.11.1779"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90032-9"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.9.2331"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/346240a0"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/346245a0"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)39758-3"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1991.tb07928.x"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.5.5.880"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2035027"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(89)90396-X"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.14.5936"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(81)90179-2"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793%2891%2981002-P","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793(91)81002-P","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/0014-5793%2891%2981002-P","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T10:32:37Z","timestamp":1694860357000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1016\/0014-5793%2891%2981002-P"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,8,19]]},"references-count":19,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[1991,8,19]]}},"alternative-id":["10.1016\/0014-5793(91)81002-P"],"URL":"https:\/\/doi.org\/10.1016\/0014-5793(91)81002-p","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,8,19]]}}}