{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:18:11Z","timestamp":1779340691757,"version":"3.51.4"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2001,10,19]],"date-time":"2001-10-19T00:00:00Z","timestamp":1003449600000},"content-version":"vor","delay-in-days":2559,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[1994,10,17]]},"abstract":"<jats:p>The yeast gene, <jats:italic>YTA10<\/jats:italic>, encodes a member of a novel family of putative ATPases. Yta10p, as deduced from the nucleotide sequence, is 761 amino acids in length (predicted molecular mass 84.5 kDa). The amino acid sequence of Yta10p exhibits high similarity to two other yeast proteins, Yta11 and Yta12, and to <jats:italic>E coli<\/jats:italic> FtsH. Several features of Yta10p are compatible with its localization in mitochondria. We report here that Yta10p is a yeast mitochondrial protein and that import is dependent on a membrane potential and accompanied by processing to a protein of approximately 73 kDa. Disruption of <jats:italic>YTA10<\/jats:italic> leads to a nuclear <jats:italic>petite<\/jats:italic> phenotype and to a loss of respiratory competence, as shown by spectrophotometric measurement of the activities of respiratory complexes I\u2013III and IV, respectively. These findings together with the high similarity of Yta10p to several ATP\u2010dependent proteases suggest that Yta10p is a mitochondrial component involved, directly or indirectly, in the correct assembly and\/or maintenance of active respiratory complexes.<\/jats:p>","DOI":"10.1016\/0014-5793(94)01045-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T07:57:06Z","timestamp":1027583826000},"page":"197-200","source":"Crossref","is-referenced-by-count":62,"title":["Yta10p, a member of a novel ATPase family in yeast, is essential for mitochondrial function"],"prefix":"10.1002","volume":"353","author":[{"given":"Reimund","family":"Tauer","sequence":"first","affiliation":[]},{"given":"Gertrud","family":"Mannhaupt","sequence":"additional","affiliation":[]},{"given":"Ralf","family":"Schnall","sequence":"additional","affiliation":[]},{"given":"Alexander","family":"Pajic","sequence":"additional","affiliation":[]},{"given":"Thomas","family":"Langer","sequence":"additional","affiliation":[]},{"given":"Horst","family":"Feldmann","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2001,10,19]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/yea.320100903"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(11)80001-0"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-9084(93)90079-8"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/366358a0"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.13.9.5418"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.175.5.1344-1351.1993"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.175.5.1344-1351.1993"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.22.10861"},{"key":"e_1_2_1_10_1","author":"Pajic A.","year":"1994","journal-title":"FEBS Lett."},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.12.5463"},{"key":"e_1_2_1_12_1","unstructured":"1989 Cold Spring Harbour Laboratory Cold Spring Harbour NY J. 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