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Monobromobimane does not inhibit the phosphate carrier, nor does it interfere with Ca<jats:sup>2+<\/jats:sup> transport, energy coupling or ATP production and transport. We show that monobromobimane selectively prevents the shift in pore gating potential caused by some dithiol oxidants or crosslinkers but not by increasing [Ca<jats:sup>2+<\/jats:sup>], allowing a clear distinction of the pore agonists which act at this site.<\/jats:p>","DOI":"10.1016\/0014-5793(95)00256-9","type":"journal-article","created":{"date-parts":[[2003,4,30]],"date-time":"2003-04-30T22:24:07Z","timestamp":1051741447000},"page":"239-242","source":"Crossref","is-referenced-by-count":70,"title":["Selective inhibition of the mitochondrial permeability transition pore at the oxidation\u2010reduction sensitive dithiol by monobromobimane"],"prefix":"10.1002","volume":"362","author":[{"given":"Paola","family":"Costantini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris V.","family":"Chernyak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Petronilli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Bernardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2000,3,7]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(79)90372-2"},{"key":"e_1_2_1_3_1","first-page":"357","volume":"255","author":"Crompton M.","year":"1988","journal-title":"Biochem. 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