{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T21:03:11Z","timestamp":1770498191845,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2000,3,9]],"date-time":"2000-03-09T00:00:00Z","timestamp":952560000000},"content-version":"vor","delay-in-days":1641,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEBS Letters"],"published-print":{"date-parts":[[1995,9,11]]},"abstract":"<jats:p>The interaction of Fas (Apo\u20101) and TNF receptor\u20101 with their respective ligands can lead to cell death. The so\u2010called death domain, a sequence motif present in the cytoplasmic portion of the two receptors, has been identified as a critical structural element involved in signal transduction that leads to apoptosis. Here we describe several additional proteins which contain a death domain. Novel members of this family include proteins known to be implicated not only in apoptosis but also in neuron guidance.<\/jats:p>","DOI":"10.1016\/0014-5793(95)00931-x","type":"journal-article","created":{"date-parts":[[2003,4,30]],"date-time":"2003-04-30T22:24:07Z","timestamp":1051741447000},"page":"321-323","source":"Crossref","is-referenced-by-count":93,"title":["The death domain motif found in Fas (Apo\u20101) and TNF receptor is present in proteins involved in apoptosis and axonal guidance"],"prefix":"10.1002","volume":"371","member":"311","published-online":{"date-parts":[[2000,3,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7878463"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7533326"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.14.7795"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90071-3"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90070-5"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90072-1"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/22.17.3441"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560030118"},{"key":"e_1_2_1_11_2","first-page":"10915","volume-title":"Proc. Natl. Acad. Sci. USA","author":"Henikoff S.","year":"1992"},{"key":"e_1_2_1_12_2","first-page":"53","volume-title":"Proceedings Second International Conference on Intelligent Systems for Molecular Biology","author":"Bucher P.","year":"1994"},{"key":"e_1_2_1_13_2","first-page":"2444","volume-title":"Proc. Natl. Acad. Sci. USA","author":"Pearson W.R.","year":"1988"},{"key":"e_1_2_1_14_2","first-page":"53","volume":"10","author":"Rost B.","year":"1994","journal-title":"Comp. Appl. Biosci."},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.8332899"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1101\/gad.9.1.15"},{"key":"e_1_2_1_17_2","first-page":"1095","volume":"5","author":"Lord K.A.","year":"1990","journal-title":"Oncogene"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.127.3.609"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90385-2"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1995.tb07022.x"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/359328a0"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90357-I"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.129.4.1081"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90071-W"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90327-5"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90464-2"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.1.387"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)82075-0"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793%2895%2900931-X","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2F0014-5793(95)00931-X","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/0014-5793%2895%2900931-X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T07:42:58Z","timestamp":1694936578000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1016\/0014-5793%2895%2900931-X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,9,11]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,9,11]]}},"alternative-id":["10.1016\/0014-5793(95)00931-X"],"URL":"https:\/\/doi.org\/10.1016\/0014-5793(95)00931-x","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,9,11]]}}}