{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T01:05:27Z","timestamp":1772586327162,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1978,10,1]],"date-time":"1978-10-01T00:00:00Z","timestamp":276048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[1978,10]]},"DOI":"10.1016\/0092-8674(78)90024-7","type":"journal-article","created":{"date-parts":[[2004,5,4]],"date-time":"2004-05-04T11:29:28Z","timestamp":1083670168000},"page":"561-572","source":"Crossref","is-referenced-by-count":496,"title":["Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein"],"prefix":"10.1016","volume":"15","author":[{"given":"Arthur D.","family":"Levinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermann","family":"Oppermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon","family":"Levintow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold E.","family":"Varmus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.Michael","family":"Bishop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0092-8674(78)90024-7_BIB1","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1128\/JVI.21.3.1042-1055.1977","article-title":"Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus","volume":"21","author":"Becker","year":"1977","journal-title":"J. Virol."},{"key":"10.1016\/0092-8674(78)90024-7_BIB2","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1515\/znc-1976-11-1232","article-title":"Expression of virus specific morphological cell transformation induced in enucleated cells","volume":"31c","author":"Beug","year":"1976","journal-title":"Z. Naturforsch."},{"key":"10.1016\/0092-8674(78)90024-7_BIB3","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/0042-6822(70)90251-5","article-title":"The low molecular weight RNAs of Rous sarcoma virus. I. The 4S RNA","volume":"42","author":"Bishop","year":"1970","journal-title":"Virology"},{"key":"10.1016\/0092-8674(78)90024-7_BIB4","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/0042-6822(74)90412-7","article-title":"Reversion and induction of Rous sarcoma virus expression in virus-transformed baby hamster kidney cells","volume":"62","author":"Boettiger","year":"1974","journal-title":"Virology"},{"key":"10.1016\/0092-8674(78)90024-7_BIB5","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/269346a0","article-title":"Identification of a transformation-specific antigen induced by an avian sarcoma virus","volume":"269","author":"Brugge","year":"1977","journal-title":"Nature"},{"key":"10.1016\/0092-8674(78)90024-7_BIB6","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1128\/JVI.26.3.773-782.1978","article-title":"Peptide analysis of the transformation-specific antigen from avian sarcoma virus-transformed cells","volume":"26","author":"Brugge","year":"1978","journal-title":"J. Virol."},{"key":"10.1016\/0092-8674(78)90024-7_BIB7","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/0042-6822(76)90117-3","article-title":"Growth stimulation of chick embryo neuroretinal cells infected with Rous sarcoma virus: relationship to viral replication and morphological transformation","volume":"71","author":"Calothy","year":"1976","journal-title":"Virology"},{"key":"10.1016\/0092-8674(78)90024-7_BIB8","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/S0021-9258(19)75212-0","article-title":"Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis","volume":"252","author":"Cleveland","year":"1978","journal-title":"J. Biol. Chem."},{"key":"10.1016\/0092-8674(78)90024-7_BIB9","first-page":"2021","article-title":"Protein kinase activity associated with the avian sarcoma virus src gene product","volume":"75","author":"Collett","year":"1978"},{"key":"10.1016\/0092-8674(78)90024-7_BIB10","first-page":"117","article-title":"Organization and expression of early genes of simian virus 40","volume":"75","author":"Crawford","year":"1978"},{"key":"10.1016\/0092-8674(78)90024-7_BIB11","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0042-6822(77)90305-1","article-title":"Characteristics of virus-specific RNA in avian sarcoma virus-transformed BHK-21 cells and revertants","volume":"76","author":"Deng","year":"1977","journal-title":"Virology"},{"key":"10.1016\/0092-8674(78)90024-7_BIB12","first-page":"4320","article-title":"RNA of avian acute leukemia virus MC29","volume":"74","author":"Duesberg","year":"1977"},{"key":"10.1016\/0092-8674(78)90024-7_BIB13","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1126\/science.22932","article-title":"Phosphorylated proteins as physiological effectors","volume":"199","author":"Greengard","year":"1978","journal-title":"Science"},{"key":"10.1016\/0092-8674(78)90024-7_BIB14","first-page":"401","article-title":"Cell transformation by RNA tumor viruses","volume":"10","author":"Hanafusa","year":"1977"},{"key":"10.1016\/0092-8674(78)90024-7_BIB15","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1128\/JVI.24.1.47-63.1977","article-title":"Size and genetic content of viral RNAs in avian oncovirus-infected cells","volume":"24","author":"Hayward","year":"1977","journal-title":"J. Virol."},{"key":"10.1016\/0092-8674(78)90024-7_BIB16","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0092-8674(78)90146-0","article-title":"10 nm filaments in normal and transformed cells","volume":"13","author":"Hynes","year":"1978","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0092-8674(78)90326-4","article-title":"Identification of a transformation-specific protein induced by a Rous sarcoma virus","volume":"13","author":"Jay","year":"1978","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB18","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/0042-6822(71)90047-X","article-title":"The effects of reciprocal changes in temperature on the transformed state of cells infected with a Rous sarcoma virus mutant","volume":"46","author":"Kawai","year":"1971","journal-title":"Virology"},{"key":"10.1016\/0092-8674(78)90024-7_BIB19","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.4049\/jimmunol.115.6.1617","article-title":"Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent; parameters of the interaction of the antibody-antigen complexes with protein A","volume":"115","author":"Kessler","year":"1975","journal-title":"J. Immunol."},{"key":"10.1016\/0092-8674(78)90024-7_BIB20","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/0092-8674(77)90298-7","article-title":"The group C adenovirus tumor antigens: identification in infected and transformed cells and a peptide map analysis","volume":"11","author":"Levinson","year":"1977","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB21","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/0092-8674(77)90164-7","article-title":"A joint product of the genes gag and pol of avian sarcoma virus: a possible precursor of reverse transcriptase","volume":"12","author":"Oppermann","year":"1977","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB22","first-page":"2490","article-title":"Visualization of a system of filaments 7\u201310 nm thick in cells of an epitheloid line (PT K2) by immunofluorescence microscopy","volume":"74","author":"Osborn","year":"1977"},{"key":"10.1016\/0092-8674(78)90024-7_BIB23","first-page":"303","article-title":"Cyclic AMP and the transformation of fibroblasts","volume":"19","author":"Pastan","year":"1974"},{"key":"10.1016\/0092-8674(78)90024-7_BIB24","first-page":"1567","article-title":"Identification of a polypeptide encoded by the avian sarcoma virus src gene","volume":"75","author":"Purchio","year":"1978"},{"key":"10.1016\/0092-8674(78)90024-7_BIB25","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/B978-0-12-152812-6.50008-1","article-title":"Soluble cyclic AMP-dependent protein kinases: review of the enzyme isolated from bovine cardiac muscle","volume":"12","author":"Rosen","year":"1977","journal-title":"Curr. Topics Cell. Reg."},{"key":"10.1016\/0092-8674(78)90024-7_BIB26","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1146\/annurev.bi.44.070175.004151","article-title":"Protein phosphorylation","volume":"44","author":"Rubin","year":"1975","journal-title":"Ann. Rev. Biochem."},{"key":"10.1016\/0092-8674(78)90024-7_BIB27","first-page":"79","article-title":"Tumor antigen(s) in cells productively infected by wild-type polyoma virus and mutant NG-18","volume":"75","author":"Schaffhausen","year":"1978"},{"key":"10.1016\/0092-8674(78)90024-7_BIB28","doi-asserted-by":"crossref","first-page":"3176","DOI":"10.1016\/S0021-9258(17)33516-0","article-title":"Purification and properties of a virion kinase","volume":"251","author":"Silberstein","year":"1978","journal-title":"J. Biol. Chem."},{"key":"10.1016\/0092-8674(78)90024-7_BIB29","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0092-8674(78)90206-4","article-title":"Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses","volume":"13","author":"Spector","year":"1978","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0092-8674(78)90205-2","article-title":"Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses","volume":"13","author":"Spector","year":"1978","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB31","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.75.9.4102","article-title":"Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in the DNA of uninfected vertebrates","author":"Spector","year":"1978"},{"key":"10.1016\/0092-8674(78)90024-7_BIB32","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/0092-8674(78)90224-6","article-title":"Avian myelocytomatosis and erythroblastosis viruses lack the transforming gene src of avian sarcoma viruses","volume":"13","author":"St\u00e9helin","year":"1978","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB33","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/260170a0","article-title":"DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA","volume":"260","author":"St\u00e9helin","year":"1976","journal-title":"Nature"},{"key":"10.1016\/0092-8674(78)90024-7_BIB34","first-page":"341","article-title":"The genetics of RNA tumor viruses","author":"Vogt","year":"1977"},{"key":"10.1016\/0092-8674(78)90024-7_BIB35","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/0092-8674(77)90163-5","article-title":"The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses","volume":"12","author":"Weiss","year":"1977","journal-title":"Cell"},{"key":"10.1016\/0092-8674(78)90024-7_BIB36","first-page":"897","article-title":"Genetic recombination among temperature-sensitive mutants of Rous sarcoma virus","volume":"39","author":"Wyke","year":"1974"}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0092867478900247?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0092867478900247?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T11:42:59Z","timestamp":1734349379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0092867478900247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,10]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1978,10]]}},"alternative-id":["0092867478900247"],"URL":"https:\/\/doi.org\/10.1016\/0092-8674(78)90024-7","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[1978,10]]}}}