{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T12:32:58Z","timestamp":1759062778300},"reference-count":61,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1990,1,1]],"date-time":"1990-01-01T00:00:00Z","timestamp":631152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers & Chemistry"],"published-print":{"date-parts":[[1990,1]]},"DOI":"10.1016\/0097-8485(90)80046-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T03:52:30Z","timestamp":1027569150000},"page":"193-200","source":"Crossref","is-referenced-by-count":44,"title":["The microcomputer OASIS system for predicting the biological activity of chemical compounds"],"prefix":"10.1016","volume":"14","author":[{"given":"Ovanes","family":"Mekenyan","sequence":"first","affiliation":[]},{"given":"Stoyan","family":"Karabunarliev","sequence":"additional","affiliation":[]},{"given":"Danail","family":"Bonchev","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/0097-8485(90)80046-5_BIB1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/jcc.540030316","volume":"3","author":"Abraham","year":"1982","journal-title":"J. Comput. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB2","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/jcc.540050609","volume":"5","author":"Abraham","year":"1984","journal-title":"J. Comput. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB3","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/jcc.540060606","volume":"6","author":"Balaban","year":"1985","journal-title":"J. Comput. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB4","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1002\/jcc.540060608","volume":"6","author":"Balaban","year":"1985","journal-title":"J. Comput. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB5","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BFb0111212","volume":"114","author":"Balaban","year":"1984","journal-title":"Topics Curr. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB6","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1021\/ja00839a001","volume":"97","author":"Bingham","year":"1975","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0097-8485(90)80046-5_BIB7","author":"Bonchev","year":"1983"},{"key":"10.1016\/0097-8485(90)80046-5_BIB8","first-page":"34","author":"Bonchev","year":"1986"},{"key":"10.1016\/0097-8485(90)80046-5_BIB9","first-page":"18","volume":"7","author":"Cramer","year":"1988","journal-title":"QSAR"},{"key":"10.1016\/0097-8485(90)80046-5_BIB10","author":"Dewar","year":"1969"},{"key":"10.1016\/0097-8485(90)80046-5_BIB11","doi-asserted-by":"crossref","first-page":"4899","DOI":"10.1021\/ja00457a004","volume":"99","author":"Dewar","year":"1977","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0097-8485(90)80046-5_BIB12","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1021\/jm00233a009","volume":"19","author":"Dunn","year":"1976","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB13","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1021\/jm00334a001","volume":"7","author":"Free","year":"1964","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB14","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1016\/0040-4020(80)80168-2","volume":"46","author":"Gasteiger","year":"1980","journal-title":"Tetrahedron"},{"key":"10.1016\/0097-8485(90)80046-5_BIB15","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/BF02163027","volume":"14","author":"Golub","year":"1970","journal-title":"Numer. Math."},{"key":"10.1016\/0097-8485(90)80046-5_BIB16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1021\/jm00223a001","volume":"19","author":"Hansch","year":"1976","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB17","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1021\/ja01062a035","volume":"86","author":"Hansch","year":"1964","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0097-8485(90)80046-5_BIB18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1021\/jm00271a039","volume":"15","author":"Hansch","year":"1972","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB19","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/0161-5890(78)90005-6","volume":"15","author":"Hansch","year":"1978","journal-title":"Immunochemistry"},{"key":"10.1016\/0097-8485(90)80046-5_BIB20","author":"Hansch","year":"1979"},{"key":"10.1016\/0097-8485(90)80046-5_BIB21","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1021\/jm00269a003","volume":"16","author":"Hansch","year":"1973","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB22","author":"Kanetti","year":"1990","journal-title":"QCPE version"},{"key":"10.1016\/0097-8485(90)80046-5_BIB23","first-page":"74","volume":"103","author":"Karabunarliev","year":"1984","journal-title":"Vychislitel'nye Systemy"},{"key":"10.1016\/0097-8485(90)80046-5_BIB24","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1002\/jps.2600700825","volume":"70","author":"Kier","year":"1981","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/0097-8485(90)80046-5_BIB25","author":"Kier","year":"1976"},{"key":"10.1016\/0097-8485(90)80046-5_BIB26","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1021\/jm00135a001","volume":"24","author":"Martin","year":"1981","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB27","first-page":"385","volume":"III","author":"Mekenyan","year":"1985","journal-title":"Proc. 3rd Int. Conf. on Chemistry and Biotechnology of Biologically Active Natural Products"},{"key":"10.1016\/0097-8485(90)80046-5_BIB28","first-page":"225","volume":"36","author":"Mekenyan","year":"1986","journal-title":"Acta Pharm. Jug."},{"key":"10.1016\/0097-8485(90)80046-5_BIB29","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/jcc.540060607","volume":"6","author":"Mekenyan","year":"1985","journal-title":"J. Comput. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB30","first-page":"240","volume":"7","author":"Mekenyan","year":"1988","journal-title":"QSAR"},{"key":"10.1016\/0097-8485(90)80046-5_BIB31","author":"Mekenyan","year":"1988","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB32","author":"Mekenyan","year":"1988","journal-title":"Proc. Merseburg Symp. Computers in Chemistry"},{"key":"10.1016\/0097-8485(90)80046-5_BIB33","unstructured":"Mekenyan O., Karabunarliev S. & Bonchev D. J. Math. Chem. (in press)."},{"key":"10.1016\/0097-8485(90)80046-5_BIB34","author":"Mekenyan","year":"1989","journal-title":"The Third Int. Mathl Chem. Conf."},{"key":"10.1016\/0097-8485(90)80046-5_BIB35","first-page":"176","volume":"36","author":"Mekenyan","year":"1986","journal-title":"Drug Res."},{"key":"10.1016\/0097-8485(90)80046-5_BIB36","first-page":"629","volume":"36","author":"Mekenyan","year":"1986","journal-title":"Drug Res."},{"key":"10.1016\/0097-8485(90)80046-5_BIB37","first-page":"415","volume":"14","author":"Mercier","year":"1979","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB38","unstructured":"Mercier C., Mekenyan O., Dubois J.-E. & Bonchev D. Eur. J. Med. Chem. (Submitted)."},{"key":"10.1016\/0097-8485(90)80046-5_BIB39","first-page":"497","volume":"46","author":"Mulliken","year":"1949","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB40","first-page":"675","volume":"46","author":"Mulliken","year":"1949","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB41","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1063\/1.1712109","volume":"47","author":"Ohno","year":"1967","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB42","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1063\/1.1698963","volume":"21","author":"Pariser","year":"1953","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB43","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1063\/1.1742461","volume":"24","author":"Pariser","year":"1956","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB44","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1063\/1.1698929","volume":"21","author":"Pariser","year":"1953","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB45","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1063\/1.1699030","volume":"21","author":"Pariser","year":"1953","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB46","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/jps.2600600413","volume":"60","author":"Peradejordi","year":"1971","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/0097-8485(90)80046-5_BIB47","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1002\/jps.2600610617","volume":"61","author":"Peredejordi","year":"1972","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/0097-8485(90)80046-5_BIB48","author":"Pople","year":"1970"},{"key":"10.1016\/0097-8485(90)80046-5_BIB49","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1063\/1.1727227","volume":"44","author":"Pople","year":"1966","journal-title":"J. Chem. Phys."},{"key":"10.1016\/0097-8485(90)80046-5_BIB50","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1002\/jcc.540060611","volume":"6","author":"Ralev","year":"1985","journal-title":"J. Comput. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB51","first-page":"295","author":"Rouvray","year":"1986"},{"key":"10.1016\/0097-8485(90)80046-5_BIB52","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/scientificamerican0986-40","volume":"284","author":"Rouvray","year":"1986","journal-title":"Sci. Am."},{"key":"10.1016\/0097-8485(90)80046-5_BIB53","first-page":"189","volume":"31","author":"Sablji\u0107","year":"1981","journal-title":"Acta Pharm. Jugosl."},{"key":"10.1016\/0097-8485(90)80046-5_BIB54","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1070\/RC1988v057n03ABEH003344","volume":"57","author":"Stankevich","year":"1988","journal-title":"Usp. Khim."},{"key":"10.1016\/0097-8485(90)80046-5_BIB55","doi-asserted-by":"crossref","first-page":"3120","DOI":"10.1021\/ja01132a049","volume":"74","author":"Taft","year":"1952","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0097-8485(90)80046-5_BIB56","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1021\/ja00396a021","volume":"103","author":"Thiel","year":"1981","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0097-8485(90)80046-5_BIB57","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1021\/ja00396a022","volume":"103","author":"Thiel","year":"1981","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/0097-8485(90)80046-5_BIB58","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1021\/jm00196a017","volume":"22","author":"Topliss","year":"1979","journal-title":"J. Med. Chem."},{"key":"10.1016\/0097-8485(90)80046-5_BIB59","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/B978-0-12-060307-7.50010-9","volume":"7","author":"Verloop","year":"1976","journal-title":"Drug Design"},{"key":"10.1016\/0097-8485(90)80046-5_BIB60","first-page":"53","volume":"27","author":"Yee","year":"1976","journal-title":"Rep. Univ. Electr. Commun."},{"key":"10.1016\/0097-8485(90)80046-5_BIB61","first-page":"227","volume":"27","author":"Yee","year":"1976","journal-title":"Rep. Univ. Electr. Commun."}],"container-title":["Computers & Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0097848590800465?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0097848590800465?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,5]],"date-time":"2019-05-05T19:50:41Z","timestamp":1557085841000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0097848590800465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["0097848590800465"],"URL":"https:\/\/doi.org\/10.1016\/0097-8485(90)80046-5","relation":{},"ISSN":["0097-8485"],"issn-type":[{"value":"0097-8485","type":"print"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}