{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:13:51Z","timestamp":1760886831601},"reference-count":4,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1996,6,1]],"date-time":"1996-06-01T00:00:00Z","timestamp":833587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers &amp; Chemistry"],"published-print":{"date-parts":[[1996,6]]},"DOI":"10.1016\/0097-8485(95)00063-1","type":"journal-article","created":{"date-parts":[[2003,4,4]],"date-time":"2003-04-04T23:49:40Z","timestamp":1049500180000},"page":"193-202","source":"Crossref","is-referenced-by-count":24,"title":["PREOPT-W: A simulation program for off-line optimization of binary gradient separations in HPLC\u2014II. Data management and miscellaneous aspects of use"],"prefix":"10.1016","volume":"20","author":[{"given":"R.","family":"Cela","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Lores","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0097-8485(95)00063-1_BIB1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9673(00)80117-X","volume":"244","author":"Berridge","year":"1982","journal-title":"J.Chromatogr."},{"key":"10.1016\/0097-8485(95)00063-1_BIB2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0097-8485(95)00058-5","volume":"20","author":"Cela","year":"1996","journal-title":"Computers Chem."},{"key":"10.1016\/0097-8485(95)00063-1_BIB3","series-title":"Optimization of Chromatographic Selectivity\u2014A Guide to Methods Development","author":"Schoenmakers","year":"1986"},{"key":"10.1016\/0097-8485(95)00063-1_BIB4","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1021\/ac50047a052","volume":"51","author":"Watson","year":"1979","journal-title":"Anal. Chem."}],"container-title":["Computers &amp; Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0097848595000631?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:0097848595000631?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,14]],"date-time":"2019-04-14T01:59:10Z","timestamp":1555207150000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/0097848595000631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,6]]},"references-count":4,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,6]]}},"alternative-id":["0097848595000631"],"URL":"https:\/\/doi.org\/10.1016\/0097-8485(95)00063-1","relation":{},"ISSN":["0097-8485"],"issn-type":[{"value":"0097-8485","type":"print"}],"subject":[],"published":{"date-parts":[[1996,6]]}}}