{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T05:02:51Z","timestamp":1705122171086},"reference-count":46,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[1991,1,1]],"date-time":"1991-01-01T00:00:00Z","timestamp":662688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[1991,1]]},"DOI":"10.1016\/0145-2126(91)90470-e","type":"journal-article","created":{"date-parts":[[2004,4,19]],"date-time":"2004-04-19T13:46:32Z","timestamp":1082382392000},"page":"859-865","source":"Crossref","is-referenced-by-count":6,"title":["T-lymphocyte response to cytokines in B-chronic lymphocytic leukemia"],"prefix":"10.1016","volume":"15","author":[{"given":"Peter G.","family":"Briggs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Kraft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Atkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/0145-2126(91)90470-E_BIB1","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1182\/blood.V40.6.777.777","article-title":"Surface bound immunoglobulins as a cell marker in human lymphoproliferative diseases","volume":"40","author":"Preud'Homme","year":"1972","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB2","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/ajcp\/87.1.60","article-title":"Serum immunoglobulins and lymphocyte subsets in chronic lymphocytic leukaemia","volume":"87","author":"Davey","year":"1987","journal-title":"Am. J. clin. Path."},{"key":"10.1016\/0145-2126(91)90470-E_BIB3","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1093\/jnci\/57.3.477","article-title":"T- and B-lymphocytes in chronic lymphocytic leukemia: correlation with clinical and immunological status of the disease","volume":"57","author":"Han","year":"1976","journal-title":"J. natn. Cancer Inst."},{"key":"10.1016\/0145-2126(91)90470-E_BIB4","first-page":"1162","article-title":"Chronic lymphocytic leukaemia","volume":"1","author":"Scott","year":"1959","journal-title":"Lancet"},{"key":"10.1016\/0145-2126(91)90470-E_BIB5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/jnci\/78.1.91","article-title":"Second cancers in patients with chronic lymphocytic leukaemia","volume":"78","author":"Davis","year":"1987","journal-title":"J. natn. Cancer Inst."},{"key":"10.1016\/0145-2126(91)90470-E_BIB6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/ajh.2830250203","article-title":"Impaired synthesis of immunoglobulin in patients with chronic lymphocytic leukemia","volume":"25","author":"Kurec","year":"1987","journal-title":"Am. J. Hemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB7","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1182\/blood.V73.4.1016.1016","article-title":"Evidence that large granular lymphocytes from B-CLL patients with hypogammaglobulinemia down-regulate B-cell immunoglobulin synthesis","volume":"73","author":"Kay","year":"1989","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB8","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0145-2126(90)90044-A","article-title":"T cells and CD45R expression in B-chronic lymphocytic leukemia","volume":"14","author":"Briggs","year":"1990","journal-title":"Leukemia Res."},{"key":"10.1016\/0145-2126(91)90470-E_BIB9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/ajh.2830160109","article-title":"Analysis of T cell subsets in B-chronic lymphocytic leukaemia: A correlation with stage of disease","volume":"16","author":"Mittleman","year":"1984","journal-title":"Am. J. Hemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB10","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1365-2141.1986.tb02929.x","article-title":"Enumeration of absolute numbers of T lymphocytic subsets in B-chronic lymphocytic leukaemia using an immunoperoxidase technique: relation to clinical stage","volume":"62","author":"Markey","year":"1986","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB11","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0140-6736(73)90196-7","article-title":"Isolation of normal T cells in chronic lymphatic leukaemia","volume":"i","author":"Wybran","year":"1973","journal-title":"Lancet"},{"key":"10.1016\/0145-2126(91)90470-E_BIB12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/1097-0142(197901)43:1<109::AID-CNCR2820430117>3.0.CO;2-G","article-title":"In vitro functional studies of mononuclear cells in patients with CLL","volume":"43","author":"Han","year":"1979","journal-title":"Cancer"},{"key":"10.1016\/0145-2126(91)90470-E_BIB13","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1365-2141.1982.tb01896.x","article-title":"T-cell function in chronic lymphocytic leukaemia","volume":"50","author":"Whelan","year":"1982","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB14","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0090-1229(80)90116-6","article-title":"Functional abnormalities associated with T lymphocytes from patients with chronic lymphocytic leukemia","volume":"17","author":"Callery","year":"1980","journal-title":"Clin. Immun. Immunopath."},{"key":"10.1016\/0145-2126(91)90470-E_BIB15","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/0090-1229(81)90022-2","article-title":"Impaired T-cell responses in chronic lymphocytic leukemia: lack of suppressor cell effect","volume":"18","author":"Fernandez","year":"1981","journal-title":"Clin. Immun. Immunopath."},{"key":"10.1016\/0145-2126(91)90470-E_BIB16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/ajh.2830220109","article-title":"Abnormal T cell function in early-stage chronic lymphocytic leukemia (CLL) patients","volume":"22","author":"Perri","year":"1986","journal-title":"Am. J. Hemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB17","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1182\/blood.V57.3.418.418","article-title":"Abnormal T-cell subpopulation function in CLL: excessive suppressor and deficient helper activity with respect to B-cell proliferation","volume":"57","author":"Kay","year":"1981","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB18","first-page":"109","article-title":"Further evidence for T cell abnormalities in chronic lymphatic leukaemia of the B cell type","volume":"53","author":"Herrman","year":"1983","journal-title":"Clin. expl Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB19","first-page":"698","article-title":"Hypogammaglobulinaemia associated with abnormalities of both B and T lymphocytes in patients with chronic lymphatic leukaemia","volume":"39","author":"Hersey","year":"1980","journal-title":"Clin. Expl Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB20","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1182\/blood.V62.4.767.767","article-title":"Immunoglobulin secretory function of B cells from untreated patients with chronic lymphocytic leukemia and hypogammaglobulinemia: role of T cells","volume":"62","author":"Fernandez","year":"1983","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB21","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1182\/blood.V67.2.294.294","article-title":"Immunoregulation of B-lymphocyte colony formation by T cell subsets in patients with chronic lymphocytic leukemia","volume":"67","author":"Fernandez","year":"1986","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB22","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1182\/blood.V58.6.1182.1182","article-title":"Defective immunoregulatory T-cell function in chronic lymphocytic leukemia","volume":"58","author":"Han","year":"1981","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB23","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1002\/1097-0142(19811115)48:10<2191::AID-CNCR2820481013>3.0.CO;2-9","article-title":"T-lymphocyte subpopulations in chronic lymphatic leukemia: a qualitative and functional study","volume":"48","author":"Semenzato","year":"1981","journal-title":"Cancer"},{"key":"10.1016\/0145-2126(91)90470-E_BIB24","doi-asserted-by":"crossref","first-page":"4261","DOI":"10.4049\/jimmunol.135.6.4261","article-title":"T cells in B cell chronic lymphocytic leukemia II. Lack of antigen-specific T suppressor cells and their progenitors","volume":"135","author":"Bloem","year":"1985","journal-title":"J. Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB25","first-page":"188","article-title":"T cells in B cell chronic lymphocytic leukaemia. I. Decreased frequency of T lymphocytes secreting suppressor factor","volume":"63","author":"Bloem","year":"1986","journal-title":"Clin. expl Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB26","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.4049\/jimmunol.122.3.1087","article-title":"T cell helper defect in patients with chronic lymphocytic leukemia","volume":"122","author":"Chiorazzi","year":"1979","journal-title":"J. Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB27","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1002\/1097-0142(19840601)53:11<2481::AID-CNCR2820531120>3.0.CO;2-Z","article-title":"Lymphocyte response to pokeweed mitogen in chronic lymphocytic leukemia","volume":"53","author":"Lamberson","year":"1984","journal-title":"Cancer"},{"key":"10.1016\/0145-2126(91)90470-E_BIB28","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1111\/j.1365-2141.1984.tb03998.x","article-title":"Discrepancy between phenotypic and functional features of natural killer T-lymphocytes in B-cell chronic lymphocytic leukaemia","volume":"58","author":"Foa","year":"1984","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB29","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.4049\/jimmunol.125.3.1216","article-title":"Defective spontaneous and antibody-dependent cytotoxicity mediated by E-rosette-positive and E-rosette-negative cells in untreated patients with chronic lymphocytic leukemia: augmentation by in vitro treatment with interferon","volume":"125","author":"Platsoucas","year":"1980","journal-title":"J. Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1365-2141.1984.tb08503.x","article-title":"Normal T cell colony numbers in untreated patients with chronic lymphocytic leukaemia (CLL)","volume":"57","author":"Fernandez","year":"1984","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB31","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1365-2141.1980.tb06021.x","article-title":"Reduced T-colony forming capacity by T-lymphocytes from B-chronic lymphocytic leukaemia","volume":"46","author":"Foa","year":"1980","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB32","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1182\/blood.V58.5.1053.1053","article-title":"Characterization of the phytohemagglutinin-induced proliferating lymphocyte subpopulations in chronic lymphocytic leukaemia patients using a clonogenic agar technique and monoclonal antibodies","volume":"58","author":"Davis","year":"1981","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB33","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1365-2141.1984.tb02870.x","article-title":"Defective expression of T cell antigens in chronic lymphocytic leukaemia: relationship to T cell dysfunction","volume":"57","author":"Kay","year":"1984","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB34","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/j.1365-2141.1981.tb07274.x","article-title":"Unusual T-cell phenotype in advanced B-chronic lymphocytic leukaemia","volume":"49","author":"Matutes","year":"1981","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB35","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1365-2141.1983.tb01248.x","article-title":"The ultrastructural morphology of T lymphocytes in B-chronic lymphocytic leukaemia: a study with monoclonal antibodies and the immunogold technique","volume":"555","author":"Matutes","year":"1983","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB36","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1365-2141.1982.tb03882.x","article-title":"B-CLL cells express true endogenous E receptor after culture with T cells and mitogens","volume":"52","author":"Worman","year":"1982","journal-title":"Br. J. Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/ajcp\/80.1.69","article-title":"Sheep erythrocyte rosette formation by B chronic lymphocytic leukemia cells as a consequence of monoclonal surface immunoglobulin with \u201cForssman-like\u201d antibody activity","volume":"80","author":"Deegan","year":"1983","journal-title":"Am. J. clin. Pathol."},{"issue":"suppl. 6","key":"10.1016\/0145-2126(91)90470-E_BIB38","first-page":"80","article-title":"T lymphocyte colonies in B-cell chronic lymphocytic leukemia","volume":"7","author":"Foa","year":"1979","journal-title":"Expl Haemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB39","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/ajh.2830300203","article-title":"Malignant chronic lymphocytic leukemia cells elaborate soluable factors that down-regulate T cell and NK function","volume":"30","author":"Burton","year":"1989","journal-title":"Am. J. Hemat."},{"key":"10.1016\/0145-2126(91)90470-E_BIB40","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1182\/blood.V66.3.614.614","article-title":"Interleukin 2 (IL 2) and interferon-gamma production by T lymphocytes from patients with B-chronic lymphocytic leukemia: evidence that normally released IL 2 is absorbed by the neoplastic population","volume":"66","author":"Foa","year":"1985","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB41","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1182\/blood.V70.2.396.396","article-title":"High serum levels of soluable interleukin 2 receptor in patients with B chronic lymphocytic leukemia","volume":"70","author":"Semenzato","year":"1987","journal-title":"Blood"},{"key":"10.1016\/0145-2126(91)90470-E_BIB42","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.4049\/jimmunol.134.3.1508","article-title":"The isolation and characterisation of the human suppressor inducer T cell subset","volume":"134","author":"Morimoto","year":"1985","journal-title":"J. Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB43","series-title":"Differential effects of IL-1 on helper and inflammatory T cells","first-page":"1555","article-title":"Autocrine growth of CD4 + T cells","volume":"140","author":"Greenbaum","year":"1988"},{"key":"10.1016\/0145-2126(91)90470-E_BIB44","first-page":"9699","article-title":"Role of interleukin 1 in the activation of T lymphocytes","volume":"85","author":"Lichtman","year":"1988"},{"key":"10.1016\/0145-2126(91)90470-E_BIB45","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.4049\/jimmunol.135.4.2249","article-title":"The events of primary T cell activation can be staged by use of sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1","volume":"135","author":"Williams","year":"1985","journal-title":"J. Immun."},{"key":"10.1016\/0145-2126(91)90470-E_BIB46","series-title":"Leukocyte Typing III","first-page":"498","article-title":"Functional activity of CD5, CD9 and common leukocyte antibodies in B-chronic lymphatic leukaemia","author":"Briggs","year":"1987"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:014521269190470E?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:014521269190470E?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T01:25:20Z","timestamp":1705109120000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/014521269190470E"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,1]]},"references-count":46,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1991,1]]}},"alternative-id":["014521269190470E"],"URL":"https:\/\/doi.org\/10.1016\/0145-2126(91)90470-e","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[1991,1]]}}}