{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T14:25:47Z","timestamp":1764858347297,"version":"3.44.0"},"reference-count":56,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T00:00:00Z","timestamp":1112313600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":3065,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100008608","name":"Sumitomo Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Developmental Biology"],"published-print":{"date-parts":[[2005,4]]},"DOI":"10.1016\/j.ydbio.2005.01.011","type":"journal-article","created":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T10:14:38Z","timestamp":1107857678000},"page":"150-161","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos"],"prefix":"10.1016","volume":"280","author":[{"given":"Hidefumi","family":"Yoshioka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyasu","family":"Ishimaru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Sugiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Tsunekawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Noce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Kasahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken-ichirou","family":"Morohashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ydbio.2005.01.011_bib1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1046\/j.1365-2443.2000.00361.x","article-title":"The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans","volume":"5","author":"Asahina","year":"2000","journal-title":"Genes Cells"},{"key":"10.1016\/j.ydbio.2005.01.011_bib2","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1242\/dev.117.1.273","article-title":"Mesonephric contribution to testis differentiation in the fetal mouse","volume":"117","author":"Buehr","year":"1993","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0925-4773(99)00327-5","article-title":"The battle of the sexes","volume":"92","author":"Capel","year":"2000","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib4","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1095\/biolreprod63.6.1825","article-title":"Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules","volume":"63","author":"Clark","year":"2000","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ydbio.2005.01.011_bib5","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0092-8674(01)00284-7","article-title":"Male-to-female sex reversal in mice lacking fibroblast growth factor 9","volume":"104","author":"Colvin","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2005.01.011_bib6","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.1242\/dev.124.19.3895","article-title":"Control of dorsoventral pattern in the chick paraxial mesoderm","volume":"124","author":"Dietrich","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib7","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/0003-2697(84)90504-9","article-title":"Microcontrolled release of biologically active compounds in chick embryos: beads of 200-microns diameter for the local release of retinoids","volume":"142","author":"Eichele","year":"1984","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.ydbio.2005.01.011_bib8","doi-asserted-by":"crossref","first-page":"4798","DOI":"10.1074\/jbc.271.9.4798","article-title":"Cloning and expression of the chick anti-Mullerian hormone gene","volume":"271","author":"Eusebe","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2005.01.011_bib9","first-page":"2604","article-title":"Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression\/transduction in the chick embryo","volume":"13","author":"Fekete","year":"1993","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib10","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/BF00301831","article-title":"Formation of the chick mesonephros. 4. Course and architecture of the developing nephrons","volume":"161","author":"Friebova-Zemanova","year":"1981","journal-title":"Anat. Embryol. (Berl.)"},{"key":"10.1016\/j.ydbio.2005.01.011_bib11","doi-asserted-by":"crossref","first-page":"7953","DOI":"10.1073\/pnas.89.17.7953","article-title":"Inverted repeat structure of the Sry locus in mice","volume":"89","author":"Gubbay","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ydbio.2005.01.011_bib12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/jmor.1050880104","article-title":"A series of normal stages in the development of chick embryo","volume":"88","author":"Hamburger","year":"1951","journal-title":"J. Morphol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib13","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1242\/dev.127.11.2471","article-title":"Molecular analysis of external genitalia formation: the role of fibroblast growth factor (Fgf) genes during genital tubercle formation","volume":"127","author":"Haraguchi","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib14","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1242\/dev.120.10.2787","article-title":"Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development","volume":"120","author":"Hatano","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib15","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1046\/j.1365-2443.1996.00254.x","article-title":"Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP\/SF-1","volume":"1","author":"Hatano","year":"1996","journal-title":"Genes Cells"},{"key":"10.1016\/j.ydbio.2005.01.011_bib16","series-title":"Manipulating the mouse embryo","first-page":"11803","author":"Hogan","year":"1994"},{"key":"10.1016\/j.ydbio.2005.01.011_bib17","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0959-437X(00)00231-8","article-title":"New aspects of Wnt signaling pathways in higher vertebrates","volume":"11","author":"Huelsken","year":"2001","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib18","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1128\/jvi.61.10.3004-3012.1987","article-title":"Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retrovirus vectors","volume":"61","author":"Hughes","year":"1987","journal-title":"J. Virol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib19","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1101\/gad.938601","article-title":"Hedgehog signaling in animal development: paradigms and principles","volume":"15","author":"Ingham","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib20","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/MCB.19.1.107","article-title":"Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1\/2\/3 and SOX9","volume":"19","author":"Kamachi","year":"1999","journal-title":"Mol. Cell. Biol."},{"year":"1992","series-title":"The atlas of mouse development","author":"Kaufman","key":"10.1016\/j.ydbio.2005.01.011_bib21"},{"key":"10.1016\/j.ydbio.2005.01.011_bib22","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1210\/mend.13.8.0325","article-title":"Dax-1 as one of the target genes of Ad4BP\/SF-1","volume":"13","author":"Kawabe","year":"1999","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib23","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1242\/dev.122.9.2813","article-title":"A male-specific role for SOX9 in vertebrate sex determination","volume":"122","author":"Kent","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib24","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0378-1119(97)00270-9","article-title":"Molecular cloning of chicken FTZ-F1-related orphan receptors","volume":"197","author":"Kudo","year":"1997","journal-title":"Gene"},{"key":"10.1016\/j.ydbio.2005.01.011_bib25","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1101\/gad.965602","article-title":"Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18","volume":"16","author":"Liu","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib26","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1016\/S0960-9822(06)00415-5","article-title":"Male-specific cell migration into the developing gonad","volume":"7","author":"Martineau","year":"1997","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib27","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1101\/gad.14.6.627","article-title":"Controlling TGF-beta signaling","volume":"14","author":"Massague","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib28","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1126\/science.276.5314.955","article-title":"Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors","volume":"276","author":"Mohammadi","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.ydbio.2005.01.011_bib29","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1365-2443.1997.1060304.x","article-title":"The ontogenesis of the steroidogenic tissues","volume":"2","author":"Morohashi","year":"1997","journal-title":"Genes Cells"},{"key":"10.1016\/j.ydbio.2005.01.011_bib30","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/nrg1001","article-title":"Pattern formation: Old models out on a limb","volume":"4","author":"Niswander","year":"2003","journal-title":"Nat. Rev., Genet."},{"key":"10.1016\/j.ydbio.2005.01.011_bib31","first-page":"645","article-title":"Differential expression of three chick FGF receptor genes, FGFR1, FGFR2 and FGFR3, in limb and feather development","volume":"383B","author":"Noji","year":"1993","journal-title":"Prog. Clin. Biol. Res."},{"key":"10.1016\/j.ydbio.2005.01.011_bib32","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1093\/oxfordjournals.jbchem.a022083","article-title":"Adrenocortical and gonadal expression of the mammalian Ftz-F1 gene encoding Ad4BP\/SF-1 is independent of pituitary control","volume":"124","author":"Nomura","year":"1998","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.ydbio.2005.01.011_bib33","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1101\/gad.965702","article-title":"FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis","volume":"16","author":"Ohbayashi","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib34","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0925-4773(97)00099-3","article-title":"A vasa-like gene in zebrafish identifies putative primordial germ cells","volume":"66","author":"Olsen","year":"1997","journal-title":"Mech. Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib35","doi-asserted-by":"crossref","first-page":"3005.1","DOI":"10.1186\/gb-2001-2-3-reviews3005","article-title":"Fibroblast growth factors","volume":"2","author":"Ornitz","year":"2001","journal-title":"Genome Biol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib36","doi-asserted-by":"crossref","first-page":"15292","DOI":"10.1074\/jbc.271.25.15292","article-title":"Receptor specificity of the fibroblast growth factor family","volume":"271","author":"Ornitz","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ydbio.2005.01.011_bib37","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1006\/dbio.1999.9461","article-title":"Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development","volume":"215","author":"Raymond","year":"1999","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib38","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/0092-8674(93)90626-2","article-title":"Sonic hedgehog mediates the polarizing activity of the ZPA","volume":"75","author":"Riddle","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2005.01.011_bib39","first-page":"269","article-title":"Gonadal development of the chick embryo following microsurgically caused agenesis of the mesonephros and using interspecific quail-chick chimaeras","volume":"98","author":"Rodemer","year":"1986","journal-title":"J. Embryol. Exp. Morphol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib40","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/aja.1002020404","article-title":"FGF-2 mRNA and its antisense message are expressed in a developmentally specific manner in the chick limb bud and mesonephros","volume":"202","author":"Savage","year":"1995","journal-title":"Dev. Dyn."},{"year":"1987","series-title":"Organogenesis of the kidney","author":"Saxen","key":"10.1016\/j.ydbio.2005.01.011_bib41"},{"key":"10.1016\/j.ydbio.2005.01.011_bib42","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/S0012-1606(03)00122-2","article-title":"Cell proliferation is necessary for the determination of male fate in the gonad","volume":"258","author":"Schmahl","year":"2003","journal-title":"Dev. Biol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib43","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1242\/dev.01239","article-title":"Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination","volume":"131","author":"Schmahl","year":"2004","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib44","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/jez.1119","article-title":"Sex determination in the chicken embryo","volume":"290","author":"Smith","year":"2001","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.ydbio.2005.01.011_bib45","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/372679a0","article-title":"Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4","volume":"372","author":"Stark","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2005.01.011_bib46","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1242\/dev.127.12.2741","article-title":"Isolation of chicken vasa homolog gene and tracing the origin of primordial germ cells","volume":"127","author":"Tsunekawa","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib47","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/17068","article-title":"Female development in mammals is regulated by Wnt-4 signalling","volume":"397","author":"Vainio","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ydbio.2005.01.011_bib48","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0925-4773(99)00225-7","article-title":"Expression of FGFR1, FGFR2 and FGFR3 during early neural development in the chick embryo","volume":"90","author":"Walshe","year":"2000","journal-title":"Mech. Dev."},{"year":"1992","series-title":"Whole mount in situ hybridization of vertebrate embryos","author":"Wilkinson","key":"10.1016\/j.ydbio.2005.01.011_bib49"},{"key":"10.1016\/j.ydbio.2005.01.011_bib50","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1387\/ijdb.031778lw","article-title":"Effects of FGF9 on embryonic Sertoli cell proliferation and testicular cord formation in the mouse","volume":"48","author":"Willerton","year":"2004","journal-title":"Int. J. Dev. Biol."},{"key":"10.1016\/j.ydbio.2005.01.011_bib51","series-title":"A practical approach","first-page":"87","article-title":"In situ hybridization","author":"Xu","year":"1998"},{"key":"10.1016\/j.ydbio.2005.01.011_bib52","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1101\/gad.981202","article-title":"Desert Hedgehog\/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis","volume":"16","author":"Yao","year":"2002","journal-title":"Genes Dev."},{"key":"10.1016\/j.ydbio.2005.01.011_bib53","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1242\/dev.124.16.3157","article-title":"Zebrafish vasa homologue RNA is localized to the cleavage planes of 2- and 4-cell-stage embryos and is expressed in the primordial germ cells","volume":"124","author":"Yoon","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.ydbio.2005.01.011_bib54","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0092-8674(00)81473-7","article-title":"Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left\u2013right asymmetry","volume":"94","author":"Yoshioka","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.ydbio.2005.01.011_bib55","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/35056032","article-title":"Establishing sexual dimorphism: Conservation amidst diversity?","volume":"2","author":"Zarkower","year":"2001","journal-title":"Nat. Rev., Genet."},{"key":"10.1016\/j.ydbio.2005.01.011_bib56","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S1095-6433(02)00023-5","article-title":"Indicators of functional differentiation of the chick embryonic kidney","volume":"131","author":"Zemanova","year":"2002","journal-title":"Comp. Biochem. Physiol., Part A: Mol. Integr. Physiol."}],"container-title":["Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160605000382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012160605000382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T03:31:31Z","timestamp":1757907091000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012160605000382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4]]},"references-count":56,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,4]]}},"alternative-id":["S0012160605000382"],"URL":"https:\/\/doi.org\/10.1016\/j.ydbio.2005.01.011","relation":{},"ISSN":["0012-1606"],"issn-type":[{"type":"print","value":"0012-1606"}],"subject":[],"published":{"date-parts":[[2005,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mesonephric FGF signaling is associated with the development of sexually indifferent gonadal primordium in chick embryos","name":"articletitle","label":"Article Title"},{"value":"Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ydbio.2005.01.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}