{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:47:38Z","timestamp":1767016058190},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2000,5,1]],"date-time":"2000-05-01T00:00:00Z","timestamp":957139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers in Biology and Medicine"],"published-print":{"date-parts":[[2000,5]]},"DOI":"10.1016\/s0010-4825(00)00003-2","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T02:02:29Z","timestamp":1027648949000},"page":"135-151","source":"Crossref","is-referenced-by-count":13,"title":["Scale-independent shape analysis for quantitative cytology using mathematical morphology"],"prefix":"10.1016","volume":"30","author":[{"given":"Volker","family":"Metzler","sequence":"first","affiliation":[]},{"given":"Thomas","family":"Lehmann","sequence":"additional","affiliation":[]},{"given":"Hans","family":"Bienert","sequence":"additional","affiliation":[]},{"given":"Khosrow","family":"Mottaghy","sequence":"additional","affiliation":[]},{"given":"Klaus","family":"Spitzer","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/S0010-4825(00)00003-2_BIB1","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0142-9612(94)90246-1","article-title":"Attachment of epithelial cells and fibroblasts to ceramic materials","volume":"15","author":"Niederauer","year":"1994","journal-title":"Biomaterials"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB2","series-title":"Handbook of Pattern Recognition and Image Processing","first-page":"629","article-title":"Biomedical image analysis","author":"Sklansky","year":"1986"},{"issue":"1","key":"10.1016\/S0010-4825(00)00003-2_BIB3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1109\/51.482844","article-title":"Quantitative microscopy","volume":"15","author":"Young","year":"1996","journal-title":"IEEE Engineering in Medicine and Biology"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB4","series-title":"An Introduction to Morphological Image Processing","author":"Dougherty","year":"1992"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB5","series-title":"Morphological Image Analysis","author":"Soille","year":"1999"},{"issue":"8","key":"10.1016\/S0010-4825(00)00003-2_BIB6","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1109\/TASSP.1987.1165254","article-title":"Morphological filters \u2014 Part II: Their relation to median, order-statistic, and stack filters","volume":"35","author":"Maragos","year":"1987","journal-title":"IEEE Trans. on Acoustics, Speech, and Signal Processing"},{"issue":"2","key":"10.1016\/S0010-4825(00)00003-2_BIB7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1006\/gmip.1996.0416","article-title":"An efficient class of alternating sequential filters in morphology","volume":"59","author":"Pei","year":"1997","journal-title":"Graphical Models and Image Processing"},{"issue":"1","key":"10.1016\/S0010-4825(00)00003-2_BIB8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/1047-3203(90)90014-M","article-title":"Morphological segmentation","volume":"1","author":"Meyer","year":"1990","journal-title":"Journal of Visual Communication and Image Representation"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB9","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1006\/rtim.1995.1019","article-title":"Mathematical morphology for edge and overlap detection for medical images","volume":"1","author":"Godbole","year":"1995","journal-title":"Real-Time Imaging"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB10","series-title":"Image Analysis and Mathematical Morphology","author":"Serra","year":"1982"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB11","series-title":"Computer-Assisted Microscopy","author":"Russ","year":"1990"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB12","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0734-189X(85)90153-7","article-title":"Image segmentation techniques","volume":"29","author":"Haralick","year":"1985","journal-title":"Computer Vision, Graphic and Image Processing"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB13","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/S0167-8655(97)00083-4","article-title":"Evaluation and comparison of different segmentation algorithms","volume":"18","author":"Zhang","year":"1997","journal-title":"Pattern Recognition Letters"},{"issue":"1","key":"10.1016\/S0010-4825(00)00003-2_BIB14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1109\/10.362924","article-title":"Live cell image segmentation","volume":"42","author":"Wu","year":"1995","journal-title":"IEEE Trans. on Biomedical Engineering"},{"issue":"3","key":"10.1016\/S0010-4825(00)00003-2_BIB15","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0010-4825(96)00004-2","article-title":"Image analysis of tissue sections","volume":"26","author":"Ong","year":"1996","journal-title":"Computers in Biology and Medicine"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB16","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1117\/12.310852","article-title":"A deformable model for the segmentation of cytological samples","volume":"3338","author":"Metzler","year":"1998","journal-title":"Proceedings of SPIE"},{"issue":"4","key":"10.1016\/S0010-4825(00)00003-2_BIB17","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/00002480-199907000-00004","article-title":"A novel method for quantifying shape deformation applied to biocompatibility testing","volume":"45","author":"Metzler","year":"1999","journal-title":"ASAIO Journal"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB18","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0165-1684(92)90008-K","article-title":"Size-sensitive multiresolution decomposition of images with rank order based filters","volume":"27","author":"Salembier","year":"1992","journal-title":"Signal Processing"},{"issue":"2","key":"10.1016\/S0010-4825(00)00003-2_BIB19","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1006\/cviu.1997.0626","article-title":"Morphological scale space for 2D shape smoothing","volume":"70","author":"Jang","year":"1998","journal-title":"Computer Vision and Image Understanding"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB20","series-title":"Digital Image Processing","author":"Gonzales","year":"1993"},{"issue":"8","key":"10.1016\/S0010-4825(00)00003-2_BIB21","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1109\/PROC.1968.6570","article-title":"Nonlinear filtering of multiplied and convolved signals","volume":"56","author":"Oppenheim","year":"1968","journal-title":"Proceedings of the IEEE"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB22","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0734-189X(89)90039-X","article-title":"Illumination independent change detection for real world image sequences","volume":"46","author":"Skifstad","year":"1989","journal-title":"Computer Vision, Graphics, and Image Processing"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB23","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1109\/TSMC.1979.4310076","article-title":"A threshold selection method from grey level histograms","volume":"9","author":"Otsu","year":"1979","journal-title":"IEEE Trans. on Systems, Man, and Cybernetics"},{"issue":"4","key":"10.1016\/S0010-4825(00)00003-2_BIB24","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0031-3203(97)00062-9","article-title":"New results on the theory of morphological filters by reconstruction","volume":"31","author":"Crespo","year":"1998","journal-title":"Pattern Recognition"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1117\/12.144751","article-title":"Watershed segmentation of binary images using distance transformations","volume":"1902","author":"Orbert","year":"1992","journal-title":"Proceedings of SPIE"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB26","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0734-189X(86)80047-0","article-title":"Distance transforms in digital images","volume":"34","author":"Borgefors","year":"1986","journal-title":"Computer Vision, Graphics and Image Processing"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB27","doi-asserted-by":"crossref","first-page":"7","DOI":"10.2307\/2290446","article-title":"Ice-flow identification in satellite images using mathematical morphology and clustering about principal curves","volume":"87","author":"Banfield","year":"1992","journal-title":"Journal of American Statistical Association"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB28","series-title":"Image Analysis for the Biological Sciences","author":"Glasbery","year":"1995"},{"issue":"2","key":"10.1016\/S0010-4825(00)00003-2_BIB29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0010-4825(97)83769-9","article-title":"A comparison of similarity measures for digital subtraction radiography","volume":"27","author":"Lehmann","year":"1997","journal-title":"Computers in Biology and Medicine"},{"issue":"2","key":"10.1016\/S0010-4825(00)00003-2_BIB30","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1177\/088532829400900204","article-title":"Studies on the standardization of cytotoxicity tests and new standard reference materials useful for evaluating the safety of biomaterials","volume":"9","author":"Tsuchiya","year":"1994","journal-title":"Journal of Biomaterial Application"},{"issue":"5","key":"10.1016\/S0010-4825(00)00003-2_BIB31","first-page":"341","article-title":"A comparative mathematical evaluation of contour irregularity using form factor and PERBAS, a new analytic shape factor","volume":"11","author":"Payne","year":"1989","journal-title":"Analytical and Quantitative Cytology and Histology"},{"key":"10.1016\/S0010-4825(00)00003-2_BIB32","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1109\/TASSP.1981.1163708","article-title":"A theoretic analysis of the properties of median filters","volume":"29","author":"Gallagher","year":"1981","journal-title":"IEEE Trans. on Acoustics, Speech, and Signal Processing"},{"issue":"7","key":"10.1016\/S0010-4825(00)00003-2_BIB33","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1109\/34.192465","article-title":"Pattern spectrum and multiscale shape representation","volume":"11","author":"Maragos","year":"1989","journal-title":"IEEE Trans. on Pattern Analysis and Machine Intelligence"}],"container-title":["Computers in Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010482500000032?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0010482500000032?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T03:58:48Z","timestamp":1555300728000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0010482500000032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,5]]}},"alternative-id":["S0010482500000032"],"URL":"https:\/\/doi.org\/10.1016\/s0010-4825(00)00003-2","relation":{},"ISSN":["0010-4825"],"issn-type":[{"value":"0010-4825","type":"print"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}