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The TRUNDD transcript was detected in multiple human tissues. TRUNDD is highly homologous to all known TRAIL receptors and has an extracellular TRAIL\u2010binding domain but lacks a functional intracellular death domain and does not induce apoptosis. Consistent with an inhibitory role, ectopic expression of TRUNDD attenuated TRAIL\u2010induced apoptosis in mammalian cells.<\/jats:p>","DOI":"10.1016\/s0014-5793(98)00135-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T15:03:33Z","timestamp":1027609413000},"page":"41-45","source":"Crossref","is-referenced-by-count":245,"title":["TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling"],"prefix":"10.1002","volume":"424","author":[{"given":"Guohua","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-liang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Fei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishva M","family":"Dixit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1998,3,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7878463"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7878464"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7533326"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90057-8"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.22.12687"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.276.5309.111"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5327.815"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5327.818"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.17.5386"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.186.7.1165"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.159.1.1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.41.25417"},{"key":"e_1_2_6_14_1","first-page":"1","volume":"12","author":"Baker S.J.","year":"1996","journal-title":"Oncogene"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1006\/smim.1996.0055"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/10.1.1"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0952-7915(94)90119-8"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1296-1306"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.274.5289.990"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(02)70791-4"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/384372a0"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80244-7"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.9.4615"}],"container-title":["FEBS Letters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2FS0014-5793%2898%2900135-5","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1016%2FS0014-5793(98)00135-5","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/S0014-5793%2898%2900135-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T07:09:14Z","timestamp":1694934554000},"score":1,"resource":{"primary":{"URL":"https:\/\/febs.onlinelibrary.wiley.com\/doi\/10.1016\/S0014-5793%2898%2900135-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3,6]]},"references-count":22,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[1998,3,6]]}},"alternative-id":["10.1016\/S0014-5793(98)00135-5"],"URL":"https:\/\/doi.org\/10.1016\/s0014-5793(98)00135-5","archive":["Portico"],"relation":{},"ISSN":["0014-5793","1873-3468"],"issn-type":[{"value":"0014-5793","type":"print"},{"value":"1873-3468","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,3,6]]}}}