{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T18:16:09Z","timestamp":1715537769438},"reference-count":39,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[1985,10,1]],"date-time":"1985-10-01T00:00:00Z","timestamp":496972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mayo Clinic Proceedings"],"published-print":{"date-parts":[[1985,10]]},"DOI":"10.1016\/s0025-6196(12)60746-0","type":"journal-article","created":{"date-parts":[[2012,12,13]],"date-time":"2012-12-13T11:07:38Z","timestamp":1355396858000},"page":"697-713","source":"Crossref","is-referenced-by-count":28,"title":["Oncogenes"],"prefix":"10.1016","volume":"60","author":[{"given":"HYMIE","family":"GORDON","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0025-6196(12)60746-0_bib1","first-page":"27","article-title":"Doctor Rous's remarkable rooster","year":"1959","journal-title":"Today's Health"},{"key":"10.1016\/S0025-6196(12)60746-0_bib2","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1084\/jem.12.5.696","article-title":"A transmissible avian neoplasm (sarcoma of the common fowl)","volume":"12","author":"Rous","year":"1910","journal-title":"J Exp Med"},{"key":"10.1016\/S0025-6196(12)60746-0_bib3","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1084\/jem.13.4.397","article-title":"A sarcoma of the fowl transmissible by an agent separable from the tumor cells","volume":"13","author":"Rous","year":"1911","journal-title":"J Exp Med"},{"key":"10.1016\/S0025-6196(12)60746-0_bib4","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/312070a0","article-title":"Evidence for two distinct c-src loci on human chromosomes 1 and 20","volume":"312","author":"Le Beau","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/310581a0","article-title":"Chromosomal localization of the human proto-oncogene c-ets","volume":"310","author":"De Taisne","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib6","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/312513a0","article-title":"The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen","volume":"312","author":"Schechter","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/311029a0","article-title":"Molecular cloning of a new transforming gene from a chemically transformed human cell line","volume":"311","author":"Cooper","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib8","first-page":"1","article-title":"Human gene mapping 7","volume":"37","author":"Sparkes","year":"1984","journal-title":"Cytogenet Cell Genet"},{"key":"10.1016\/S0025-6196(12)60746-0_bib9","first-page":"451","volume":"Vol 3","author":"O'Brien","year":"1984"},{"key":"10.1016\/S0025-6196(12)60746-0_bib10","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/305112a0","article-title":"Identification and molecular cloning of the human Blym transforming gene activated in Burkitt's lymphomas","volume":"305","author":"Diamond","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib11","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1073\/pnas.75.4.2021","article-title":"Protein kinase activity associated with the avian sarcoma virus src gene product","volume":"75","author":"Collett","year":"1978","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0025-6196(12)60746-0_bib12","doi-asserted-by":"crossref","first-page":"5355","DOI":"10.1073\/pnas.76.10.5355","article-title":"Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses","volume":"76","author":"Scolnick","year":"1979","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0025-6196(12)60746-0_bib13","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/315242a0","article-title":"Primary structure of the \u03b1-subunit of transducin and its relationship to ras proteins","volume":"315","author":"Tanabe","year":"1985","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib14","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/296262a0","article-title":"Nuclear localization and DNA binding of the transforming gene product of avian myelocytomatosis virus","volume":"296","author":"Donner","year":"1982","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib15","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/304035a0","article-title":"Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus","volume":"304","author":"Waterfield","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib16","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1126\/science.6304883","article-title":"Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor","volume":"221","author":"Doolittle","year":"1983","journal-title":"Science"},{"key":"10.1016\/S0025-6196(12)60746-0_bib17","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/307521a0","article-title":"Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences","volume":"307","author":"Downward","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib18","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/302033a0","article-title":"Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue","volume":"302","author":"Capon","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib19","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/312071a0","article-title":"Biological properties of human c-Ha-ras1 genes mutated at codon 12","volume":"312","author":"Seeburg","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib20","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/315382a0","article-title":"Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats","volume":"315","author":"Zarbl","year":"1985","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib21","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1126\/science.6322298","article-title":"A transforming ras gene in tumorigenic guinea pig cell lines initiated by diverse chemical carcinogens","volume":"223","author":"Sukumar","year":"1984","journal-title":"Science"},{"key":"10.1016\/S0025-6196(12)60746-0_bib22","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1126\/science.6356357","article-title":"Translocations among antibody genes in human cancer","volume":"222","author":"Leder","year":"1983","journal-title":"Science"},{"key":"10.1016\/S0025-6196(12)60746-0_bib23","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/300765a0","article-title":"A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia","volume":"300","author":"De Klein","year":"1982","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib24","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1126\/science.6648531","article-title":"The human gene for the \u03b2 subunit of nerve growth factor is located on the proximal short arm of chromosome 1","volume":"222","author":"Francke","year":"1983","journal-title":"Science"},{"key":"10.1016\/S0025-6196(12)60746-0_bib25","doi-asserted-by":"crossref","first-page":"4188","DOI":"10.1073\/pnas.77.7.4188","article-title":"Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7","volume":"77","author":"Davies","year":"1980","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0025-6196(12)60746-0_bib26","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1038\/310781a0","article-title":"Human chromosomal mapping of genes for insulin-like growth factors I and II and epidermal growth factor","volume":"310","author":"Brissenden","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib27","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/305641a0","article-title":"The c-Ha-ras1, insulin and \u03b2-globin loci map outside the deletion associated with aniridia-Wilms' tumour","volume":"305","author":"De Martinville","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib28","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF00273006","article-title":"Trisomy 11p15 and Beckwith-Wiedemann syndrome: a report of two cases","volume":"67","author":"Turleau","year":"1984","journal-title":"Hum Genet"},{"key":"10.1016\/S0025-6196(12)60746-0_bib29","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/309585a0","article-title":"Message of myc in context","volume":"309","author":"Robertson","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib30","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1073\/pnas.80.6.1707","article-title":"Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma","volume":"80","author":"Alitalo","year":"1983","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/S0025-6196(12)60746-0_bib31","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/305245a0","article-title":"Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour","volume":"305","author":"Schwab","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib32","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0092-8674(83)90417-8","article-title":"Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus","volume":"33","author":"Fung","year":"1983","journal-title":"Cell"},{"key":"10.1016\/S0025-6196(12)60746-0_bib33","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1126\/science.6719137","article-title":"Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage","volume":"224","author":"Brodeur","year":"1984","journal-title":"Science"},{"key":"10.1016\/S0025-6196(12)60746-0_bib34","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/309458a0","article-title":"Expression and amplification of the N-myc gene in primary retinoblastoma","volume":"309","author":"Lee","year":"1984","journal-title":"Nature"},{"key":"10.1016\/S0025-6196(12)60746-0_bib35","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1126\/science.6610211","article-title":"Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation","volume":"224","author":"Tsujimoto","year":"1984","journal-title":"Science"},{"key":"10.1016\/S0025-6196(12)60746-0_bib36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/scientificamerican0884-70","article-title":"The proteins of oncogenes","volume":"251","author":"Hunter","year":"1984","journal-title":"Sci Am"},{"key":"10.1016\/S0025-6196(12)60746-0_bib37","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0092-8674(81)90263-4","article-title":"Enemies within: the genesis of retrovirus oncogenes","volume":"23","author":"Bishop","year":"1981","journal-title":"Cell"},{"key":"10.1016\/S0025-6196(12)60746-0_bib38","series-title":"Biochemistry: The Molecular Basis of Cell Structure and Function","first-page":"3","author":"Lehninger","year":"1975"},{"key":"10.1016\/S0025-6196(12)60746-0_bib39","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/S0140-6736(84)92058-0","article-title":"Genomic alterations involving the C-Myc proto-oncogene locus during the evolution of a case of chronic granulocytic leukaemia","volume":"2","author":"McCarthy","year":"1984","journal-title":"Lancet"}],"container-title":["Mayo Clinic Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619612607460?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0025619612607460?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T02:54:20Z","timestamp":1540004060000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0025619612607460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,10]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1985,10]]}},"alternative-id":["S0025619612607460"],"URL":"https:\/\/doi.org\/10.1016\/s0025-6196(12)60746-0","relation":{},"ISSN":["0025-6196"],"issn-type":[{"value":"0025-6196","type":"print"}],"subject":[],"published":{"date-parts":[[1985,10]]}}}