{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T01:13:55Z","timestamp":1771550035852,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2001,9,1]],"date-time":"2001-09-01T00:00:00Z","timestamp":999302400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropharmacology"],"published-print":{"date-parts":[[2001,9]]},"DOI":"10.1016\/s0028-3908(01)00085-5","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T21:20:16Z","timestamp":1027632016000},"page":"517-522","source":"Crossref","is-referenced-by-count":85,"title":["RS 67333 and D-cycloserine accelerate learning acquisition in the rat"],"prefix":"10.1016","volume":"41","author":[{"given":"V\u00e9ronique","family":"Lelong","sequence":"first","affiliation":[]},{"given":"Fran\u00e7ois","family":"Dauphin","sequence":"additional","affiliation":[]},{"given":"Michel","family":"Boulouard","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0028-3908(01)00085-5_BIB1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0014-2999(97)01512-4","article-title":"Tetrahydroaminoacridine and D-cycloserine stimulate acquisition of water maze spatial navigation in aged rats","volume":"19","author":"Aura","year":"1998","journal-title":"European Journal of Pharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1101\/lm.3.2-3.124","article-title":"Functional integrity of NMDA-dependent LTP induction mechanisms across the lifespan of F-344 rats","volume":"3","author":"Barnes","year":"1996","journal-title":"Learning and Memory"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB3","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0028-3908(99)00010-6","article-title":"A review of central 5-HT receptors and their function","volume":"38","author":"Barnes","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0197-4580(94)90114-7","article-title":"D-cycloserine, a novel cognitive enhancer, improves spatial memory in aged rats","volume":"15","author":"Baxter","year":"1994","journal-title":"Neurobiology of Aging"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0764-4469(97)89825-3","article-title":"5-HT4 receptors: long-term blockade of K+ channels and effects on olfactory memory","volume":"321","author":"Bockaert","year":"1998","journal-title":"Comptes Rendus Academy of Science III"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3109\/00207458909002151","article-title":"The use of the Morris water maze in the study of memory and learning","volume":"48","author":"Brandeis","year":"1989","journal-title":"International Journal of Neuroscience"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB7","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3109\/07853890008998828","article-title":"Role of serotonin in memory impairment","volume":"32","author":"Buhot","year":"2000","journal-title":"Annals of Medicine"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(95)00241-A","article-title":"Serotoninergic modulation of cholinergic function in the central nervous system: cognitive implications","volume":"69","author":"Cassel","year":"1995","journal-title":"Neuroscience"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB9","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1016\/S0960-894X(01)80414-5","article-title":"Synthesis and preliminary pharmacological evaluation of 2-benzyloxy substituted aryl ketones as 5-HT4 receptor antagonists","volume":"4","author":"Clark","year":"1994","journal-title":"Bioorganic and Medicinal Chemistry Letters"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB10","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1097\/00001756-199406020-00018","article-title":"5-HT4 receptor stimulation facilitates acetylcholine release in rat frontal cortex","volume":"5","author":"Consolo","year":"1994","journal-title":"NeuroReport"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB11","first-page":"9","article-title":"5-hydroxytryptamine (5-HT)4 receptors and central nervous system function: an update","volume":"49","author":"Eglen","year":"1997","journal-title":"Progress in Drug Research"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB12","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1111\/j.1476-5381.1995.tb16628.x","article-title":"Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo","volume":"115","author":"Eglen","year":"1995","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB13","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/0028-3908(91)90161-4","article-title":"Actions of D-cycloserine at the N-methyl-D-aspartate-associated glycine receptor site in vivo","volume":"11","author":"Emmett","year":"1991","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB14","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0163-1047(93)90886-M","article-title":"D-cycloserine attenuates scopolamine-induced learning and memory deficits in rats","volume":"59","author":"Fishkin","year":"1993","journal-title":"Behaviour and Neural Biology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB15","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0028-3908(97)00055-5","article-title":"The effects of novel, selective 5-hydroxytryptamine (5-HT)4 receptor ligands in rat spatial navigation","volume":"36","author":"Fontana","year":"1997","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB16","first-page":"1115","article-title":"Role of 5-HT4 receptors in mouse passive avoidance test","volume":"286","author":"Galeotti","year":"1998","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB17","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1006\/nlme.1998.3897","article-title":"D-cycloserine: effects on long-term retention of a conditioned response and on memory for contextual attributes","volume":"72","author":"Land","year":"1999","journal-title":"Neurobiology Learning and Memory"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB18","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1460-9568.2000.00881.x","article-title":"Combined lesions of cholinergic and serotonergic neurons in the rat brain using 192 IgG-saporin and 5,7-dihydroxytryptamine: neurochemical and behavioural characterization","volume":"12","author":"Lehmann","year":"2000","journal-title":"European Journal of Neuroscience"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB19","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0028-3908(96)00169-4","article-title":"5-HT4 receptors improve social olfactory memory in rat","volume":"36","author":"Letty","year":"1997","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB20","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0166-4328(89)90004-1","article-title":"Enhanced detection of nucleus basalis magnocellularis lesion induced spatial learning deficit in rats by modification of training regimen","volume":"31","author":"Mandel","year":"1989","journal-title":"Behaviour and Brain Research"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB21","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1016\/S0028-3908(00)00038-1","article-title":"Differential modulation of the 5-HT4 receptor agonists and antagonists on rat learning and memory","volume":"39","author":"Marchetti","year":"2000","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB22","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0028-3908(97)00058-0","article-title":"BIMU 1 increases associative memory in rats by activating 5-HT4 receptors","volume":"36","author":"Marchetti-Gauthier","year":"1997","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB23","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0165-0173(93)90006-L","article-title":"The neuropharmacological and neurochemical basis of place learning in the Morris water maze","volume":"18","author":"McNamara","year":"1993","journal-title":"Brain Research Review"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB24","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0091-3057(96)00224-9","article-title":"Effects of 5-HT4 receptor agonists and antagonists in learning","volume":"56","author":"Meneses","year":"1997","journal-title":"Pharmacology Biochemistry and Behaviour"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB25","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/0091-3057(89)90571-6","article-title":"D-cycloserine, a positive modulator of N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats","volume":"34","author":"Monahan","year":"1989","journal-title":"Pharmacology Biochemistry and Behaviour"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB26","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0023-9690(81)90020-5","article-title":"Spatial localization does not require the presence of local cues","volume":"12","author":"Morris","year":"1981","journal-title":"Learning and Motivation"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB27","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0165-0270(84)90007-4","article-title":"Developments of a water-maze procedure for studying spatial learning in rats","volume":"11","author":"Morris","year":"1984","journal-title":"Journal of Neuroscience Methods"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB28","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/BF02259655","article-title":"The effect of D-cycloserine, a partial agonist at the glycine binding site, on spatial learning and working memory in scopolamine-treated rats","volume":"9","author":"Pitk\u00e4nen","year":"1995","journal-title":"Journal of Neural Transmission (Parkinson's Disease and Dementia Section)"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB29","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0166-4328(82)90039-0","article-title":"The septo-hippocampal system and cognitive mapping","volume":"5","author":"Rawlins","year":"1982","journal-title":"Behaviour and Brain Research"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB30","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1162\/089976698300017908","article-title":"The role of the hippocampus in solving the Morris water maze","volume":"10","author":"Redish","year":"1998","journal-title":"Neural Computing"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB31","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1097\/00001756-199805110-00068","article-title":"Tetrahydroaminoacridine, a cholinesterase inhibitor, and D-cycloserine, a partial NMDA receptor-associated glycine site agonist, enhances acquisition of spatial navigation","volume":"9","author":"Riekkinen","year":"1998","journal-title":"NeuroReport"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB32","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0304-3940(92)90081-H","article-title":"D-cycloserine, a modulator of the N-methyl-D-aspartate receptor, improves spatial learning in rats treated with muscarinic antagonist","volume":"146","author":"Sirvi\u00f6","year":"1992","journal-title":"Neuroscience Letters"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB33","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s002130050529","article-title":"Enhanced delayed matching performance in younger and older macaques administered the 5-HT4 receptor agonist, RS 17017","volume":"135","author":"Terry","year":"1998","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB34","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/0306-4522(92)90139-S","article-title":"In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory site","volume":"46","author":"Thiels","year":"1992","journal-title":"Neuroscience"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB35","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0028-3908(94)90084-1","article-title":"Regional distribution and ontogeny of 5-HT4 binding sites in rodent brain","volume":"33","author":"Waeber","year":"1994","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0028-3908(01)00085-5_BIB36","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0166-4328(96)00106-4","article-title":"Characterization of [3H] GR 113808 binding to 5-HT4 receptors in brain tissues from patients with neurodegenerative disorders","volume":"73","author":"Wong","year":"1996","journal-title":"Behaviour and Brain Research"}],"container-title":["Neuropharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390801000855?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0028390801000855?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T12:27:37Z","timestamp":1555763257000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0028390801000855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["S0028390801000855"],"URL":"https:\/\/doi.org\/10.1016\/s0028-3908(01)00085-5","relation":{},"ISSN":["0028-3908"],"issn-type":[{"value":"0028-3908","type":"print"}],"subject":[],"published":{"date-parts":[[2001,9]]}}}