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Rev."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0365","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1073\/pnas.92.2.377","article-title":"Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor \u03b3 chain","volume":"92","author":"DiSanto","year":"1995","journal-title":"Proc. Natl Acad. Sci. U.S.A."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0370","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/356215a0","article-title":"Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours","volume":"356","author":"Donehower","year":"1992","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0375","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.4049\/jimmunol.148.6.1604","article-title":"Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life","volume":"148","author":"Donskoy","year":"1992","journal-title":"J. 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Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0445","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0065-2776(08)60630-6","article-title":"Positive selection of thymocytes","volume":"59","author":"Fink","year":"1995","journal-title":"Adv. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0450","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.4049\/jimmunol.146.10.3452","article-title":"Cytokine production by mature and immature thymocytes","volume":"146","author":"Fischer","year":"1991","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0455","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0952-7915(96)80027-6","article-title":"Genetic effects on immunity. Inherited disorders of lymphocyte development and function","volume":"8","author":"Fisher","year":"1996","journal-title":"Curr. Opin. 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Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_rf0485","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.4049\/jimmunol.149.5.1516","article-title":"Ontogeny and distribution of the murine B cell Fc\u03b3RII","volume":"149","author":"Foy","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0490","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1084\/jem.175.4.1067","article-title":"Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V\u03b211+ T cells","volume":"175","author":"Frey","year":"1992","journal-title":"J. Exp. 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Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0505","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/336176a0","article-title":"Abnormal differentiation of thymocytes in mice treated with cyclosporin A","volume":"336","author":"Gao","year":"1988","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0510","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/0092-8674(86)90787-7","article-title":"Diversity rearrangement and expression of murine T cell gamma genes","volume":"45","author":"Garman","year":"1986","journal-title":"Cell"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0515","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1126\/science.1542794","article-title":"The IL-6 signal transducer, gpl30: An oncostatin M receptor and affinity converter for the LIF receptor","volume":"255","author":"Gearing","year":"1992","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0520","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/0092-8674(88)90020-7","article-title":"The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene","volume":"55","author":"Geissler","year":"1988","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0525","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/ng0796-370","article-title":"Absence of integrin \u03b1 6 leads to epidermolysis bullosa and neonatal death in mice","volume":"13","author":"Georges-Labouesse","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0530","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1126\/science.1439790","article-title":"Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment","volume":"258","author":"Georgopoulos","year":"1992","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0535","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0092-8674(94)90407-3","article-title":"The Ikaros gene is required for the development of all lymphoid lineages","volume":"79","author":"Georgopoulos","year":"1994","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0540","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.immunol.15.1.155","article-title":"The role of the Ikaros gene in lymphocyte development and homeostasis","volume":"15","author":"Georgopoulos","year":"1997","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0545","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0092-8674(91)90235-Q","article-title":"Requirement for association of p56kk with CD4 in antigen-specific signal transduction in T cells","volume":"64","author":"Glaichenhaus","year":"1991","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0550","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.4049\/jimmunol.149.7.2281","article-title":"Phenotypic and functional characterisation of c-kit expression during intrathymic T cell development","volume":"149","author":"Godfrey","year":"1992","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0555","doi-asserted-by":"crossref","first-page":"4244","DOI":"10.4049\/jimmunol.150.10.4244","article-title":"A developmental pathway involving four phenotypically and functionally distinct subsets of CD3\u2212CD4\u2212CD8\u2212 triple-negative adult mouse thymocytes defined by CD44 and CD25 expression","volume":"150","author":"Godfrey","year":"1993","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0560","doi-asserted-by":"crossref","first-page":"4783","DOI":"10.4049\/jimmunol.152.10.4783","article-title":"Onset of TCR-\u03b2 gene rearrangement and role of TCR-\u03b2 expression during CD3\u2212CD4\u2212CD8\u2212 thymocyte differentiation","volume":"152","author":"Godfrey","year":"1994","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0565","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1084\/jem.163.1.1","article-title":"Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors","volume":"163","author":"Goldschneider","year":"1986","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0570","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/0092-8674(90)90342-C","article-title":"Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily","volume":"60","author":"Goodwin","year":"1990","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_rf0575","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/1074-7613(95)90131-0","article-title":"Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement","volume":"3","author":"Grawunder","year":"1995","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0580","first-page":"31","article-title":"Regulation of recombination activating gene expression during lymphocyte development","volume":"217","author":"Grawunder","year":"1996","journal-title":"Curr. Top. Microbiol. 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Today"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0595","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1002\/j.1460-2075.1992.tb05339.x","article-title":"T cell receptor (TCR) \u03b2 chain homodimers on the surface of immature but not mature \u03b1, \u03b3, \u03b2 chain deficient T cell lines","volume":"11","author":"Groettrup","year":"1992","journal-title":"EMBO J."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0600","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0092-8674(93)80070-U","article-title":"A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor \u03b2 chain and a 33 kd glycoprotein","volume":"75","author":"Groettrup","year":"1993","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0605","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1074-7613(00)80498-7","article-title":"Fyn can partially substitute for Lck in T lymphocyte development","volume":"5","author":"Groves","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0610","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1126\/science.1910207","article-title":"Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice","volume":"253","author":"Grusby","year":"1991","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0615","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1084\/jem.181.3.1187","article-title":"Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor \u03b2 chain-independent pathway","volume":"181","author":"Guidos","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0620","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1084\/jem.180.2.673","article-title":"Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation","volume":"180","author":"Guy-Grand","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0625","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1002\/eji.1830171013","article-title":"Correlation of T cell receptor gene rearrangements to T cell surface antigen expression and to serum immunoglobulin level in scid mice","volume":"17","author":"Habu","year":"1987","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0630","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1073\/pnas.92.2.354","article-title":"T cells with two functional antigen-specific receptors","volume":"92","author":"Hardardottir","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0635","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1084\/jem.173.5.1213","article-title":"Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow","volume":"173","author":"Hardy","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0640","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1084\/jem.184.3.1137","article-title":"Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus","volume":"184","author":"Hattori","year":"1996","journal-title":"J. Exp. 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Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_rf0665","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1002\/eji.1830250622","article-title":"Expression of two T cell receptor \u03b1 chains on the surface of normal murine T cells","volume":"25","author":"Heath","year":"1995","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0670","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1002\/eji.1830260839","article-title":"T lymphocyte development in the absence of Fc epsilon receptor I \u03b3 subunit: Analysis of thymic-dependent and independent \u03b1 \u03b2 and \u03b3 \u03b4 pathways","volume":"26","author":"Heiken","year":"1996","journal-title":"Eur. J. 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Res."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0790","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1126\/science.3262237","article-title":"Effects of cyclosporine A on T cell development and clonal deletion","volume":"241","author":"Jenkins","year":"1988","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0795","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0952-7915(94)90104-X","article-title":"Fetal thymic organ cultures","volume":"6","author":"Jenkinson","year":"1994","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0800","first-page":"51","article-title":"T-cell differentiation in thymus organ cultures","volume":"2","author":"Jenkinson","year":"1990","journal-title":"Semin. 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Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0820","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1084\/jem.184.4.1449","article-title":"Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop","volume":"184","author":"Kanamori","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0825","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.4049\/jimmunol.158.7.3118","article-title":"Hemopoietic progenitors in the murine fetal liver capable of rapidly generating T cells","volume":"158","author":"Kawamoto","year":"1997","journal-title":"J. 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J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0910","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1084\/jem.179.6.1957","article-title":"CD3+CD16+NK1.1+B22O+ Large granular lymphocytes arise from both \u03b1\u03b2TCR+CD4\u2212CD8+ and \u03b3\u03b4TCR+CD4\u2212CD8\u2212 cells","volume":"179","author":"Koyasu","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0915","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/341742a0","article-title":"T cell depletion in transgenic mice carrying a mutant gene for TCR \u03b2","volume":"341","author":"Krimpenfort","year":"1989","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0920","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1146\/annurev.iy.04.040186.002525","article-title":"The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition","volume":"4","author":"Kronenberg","year":"1986","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0925","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1084\/jem.186.5.767","article-title":"Allelic exclusion in pT\u03b1\u2212\/\u2212 mice: No evidence for cell surface expression of two different TCR\u03b2 chains but less efficient inhibition of endogeneous \u03b2-rearrangements in the presence of a TCR\u03b2 transgene","volume":"186","author":"Krotkova","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0930","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1126\/science.1948049","article-title":"Generation and analysis of interleukin-4 deficient mice","volume":"254","author":"Kuhn","year":"1991","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0935","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0092-8674(93)80068-P","article-title":"Interleukin-10-deficient mice develop chronic enterocolitis","volume":"75","author":"Kuhn","year":"1993","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0940","doi-asserted-by":"crossref","first-page":"2000","DOI":"10.1126\/science.7535475","article-title":"Altered cytokine export and apoptosis in mice deficient in interleukin-1 \u03b2 converting enzyme","volume":"267","author":"Kuida","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb0945","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1073\/pnas.90.2.770","article-title":"Transforming growth factor \u03b2 1 null mutation in mice causes excessive inflammatory response and early death","volume":"90","author":"Kulkarni","year":"1993","journal-title":"Proc. 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Chem."},{"key":"10.1016\/S0065-2776(08)60606-9_bb0995","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1600-065X.1995.tb00095.x","article-title":"Role of the cytokine receptor \u03b3 chain in cytokine signaling and lymphoid development","volume":"148","author":"Leonhard","year":"1995","journal-title":"Immunol. Rev."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1000","doi-asserted-by":"crossref","first-page":"5876","DOI":"10.1002\/j.1460-2075.1996.tb00974.x","article-title":"Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death","volume":"15","author":"Lerner","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1005","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/1074-7613(95)90056-X","article-title":"Receptors and signals in early thymic selection","volume":"3","author":"Levelt","year":"1995","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1010","doi-asserted-by":"crossref","first-page":"11401","DOI":"10.1073\/pnas.90.23.11401","article-title":"Restoration of early thymocyte differentiation in T-cell receptor \u03b2-chain-deficient mutant mice by trans-membrane signaling through CD3 epsilon","volume":"90","author":"Levelt","year":"1993","journal-title":"Proc. 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Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1345","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1126\/science.270.5237.800","article-title":"Defective lymphoid development in mice lacking Jak3","volume":"270","author":"Nosaka","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1350","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1084\/jem.174.1.63","article-title":"Expression and function of c-kit in hemopoietic progenitor cells","volume":"174","author":"Ogawa","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1355","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1242\/dev.117.3.1089","article-title":"Expression and function of c-Kit in fetal hemopoietic progenitor cells: Transition from the early c-Kit-independent to the late c-Kit-dependent wave of hemopoiesis in the murine embryo","volume":"117","author":"Ogawa","year":"1993","journal-title":"Development (Cambridge, UK)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1360","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1182\/blood.V87.3.956.bloodjournal873956","article-title":"Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor \u03b3 chain","volume":"87","author":"Ohbo","year":"1996","journal-title":"Blood"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1365","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1093\/intimm\/5.11.1403","article-title":"TCR isoform containing the Fc receptor \u03b3 chain exhibits structural and functional differences from isoform containing CD3 \u03b6","volume":"5","author":"Ohno","year":"1993","journal-title":"Int. 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Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1380","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-2478(91)90234-2","article-title":"Prothymocyte seeding in the thymus","volume":"27","author":"O'Neil","year":"1991","journal-title":"Immunol. Lett."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1385","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S1074-7613(00)80337-4","article-title":"Induction of TCR gene rearrangements in uncommitted stem cells by a subset of IL-7 producing, class II-expressing thymic stromal cells","volume":"6","author":"Oosterwegel","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1390","first-page":"217","article-title":"Interleukin-7R\u03b1 mRNA expression increases as stem cells differentiate into T and B lymphocyte progenitors","volume":"25","author":"Orlic","year":"1997","journal-title":"Exp. Hematol."},{"key":"10.1016\/S0065-2776(08)60606-9_rf1395","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/347189a0","article-title":"Family of disulphide-linked dimers containing the \u03b6 and \u03b7 chains of the T-cell receptor and the \u03b3 chain of Fc receptors","volume":"347","author":"Orloff","year":"1990","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1400","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1002\/eji.1830261012","article-title":"Raf regulates positive selection","volume":"26","author":"O'Shea","year":"1996","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1405","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1084\/jem.129.2.431","article-title":"Tissue interaction in the development of thymus lymphocytes","volume":"129","author":"Owen","year":"1969","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1410","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1126\/science.8211163","article-title":"Expression of two T cell receptor \u03b1 chains: Dual receptor T cells","volume":"262","author":"Padovan","year":"1993","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1415","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1084\/jem.181.4.1587","article-title":"Normal T lymphocytes can express two different T cell receptor \u03b2 chains: Implications for the mechanism of allelic exclusion","volume":"181","author":"Padovan","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1420","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.4049\/jimmunol.140.5.1431","article-title":"Synergistic effect of colony-stimulating factors and IL-2 on prothymocyte proliferation linked to the maturation of macrophage\/dendritic cells within L3T4\u2212yt-2\u2212Ia\u2212Mac\u2212 cells","volume":"140","author":"Papiernik","year":"1988","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1425","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/1074-7613(95)90066-7","article-title":"Developmental defects of lymphoid cells in Jak3 kinase-deficient mice","volume":"3","author":"Park","year":"1995","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1430","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S1074-7613(00)80512-9","article-title":"Intrathymic \u03b4 selection events in \u03b3\u03b4 cell development","volume":"7","author":"Passoni","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1435","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1073\/pnas.86.5.1614","article-title":"A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor","volume":"86","author":"Pearse","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1440","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/eji.1830240345","article-title":"In vitro development of B cells and macrophages from early mouse fetal thymocytes","volume":"24","author":"Peault","year":"1994","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1445","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1084\/jem.180.5.1955","article-title":"Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice","volume":"180","author":"Peschon","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1450","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1084\/jem.172.6.1583","article-title":"Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4 and CD8 acquisition in vivo and in vitro","volume":"172","author":"Petrie","year":"1990","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1455","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1084\/jem.178.2.615","article-title":"Multiple rearrangements in T cell receptor \u03b1 chain genes maximize the production of useful thymocytes","volume":"178","author":"Petrie","year":"1993","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1460","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1084\/jem.182.1.121","article-title":"T cell receptor gene recombination patterns and mechanisms: Cell death, rescue, and T cell production","volume":"182","author":"Petrie","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1465","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/0092-8674(93)90134-C","article-title":"Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection","volume":"73","author":"Pfeffer","year":"1993","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1470","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1084\/jem.175.4.1055","article-title":"Ontogeny of human natural killer (NK) cells: Fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon, \u03b4 proteins","volume":"175","author":"Phillips","year":"1992","journal-title":"J. Exp. 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Genet."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1485","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1084\/jem.174.4.775","article-title":"Surface expression of a T cell receptor \u03b2 (TCR-\u03b2) chain in the absence of TCR-\u03b1, -\u03b4, and -\u03b3 proteins","volume":"174","author":"Punt","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1490","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1126\/science.1570513","article-title":"A phenotype or not: Targeting genes in the immune system [news]","volume":"256","author":"Rajewsky","year":"1992","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1495","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/314101a0","article-title":"Expression and function of interleukin-2 receptors on immature thymocytes","volume":"314","author":"Raulet","year":"1985","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1500","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/314103a0","article-title":"Developmental regulation of T-cell receptor gene expression","volume":"314","author":"Raulet","year":"1985","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1505","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1146\/annurev.iy.09.040191.002325","article-title":"Fc receptors","volume":"9","author":"Ravetch","year":"1991","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1510","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1084\/jem.181.3.1223","article-title":"Transgenic expression of interleukin 7 restores T cell populations in nude mice","volume":"181","author":"Rich","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1515","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1073\/pnas.92.3.855","article-title":"A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development","volume":"92","author":"Riethmacher","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1520","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/0167-5699(93)90250-O","article-title":"Development in the thymus: It takes two to tango","volume":"14","author":"Ritter","year":"1993","journal-title":"Immunol. Today"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1525","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/0952-7915(95)80002-6","article-title":"Pathways from hematopoietic stem cells to thymocytes","volume":"7","author":"Rodewald","year":"1995","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1530","doi-asserted-by":"crossref","DOI":"10.1016\/S0145-305X(98)00013-5","article-title":"Antigen receptor junctional diversity in growth factor receptor deficient mice","author":"Rodewald","year":"1998","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1535","doi-asserted-by":"crossref","first-page":"15974","DOI":"10.1016\/S0021-9258(18)98503-0","article-title":"The high affinity Fc epsilon receptor \u03b3 subunit (Fc epsilon RI \u03b3) facilitates T cell receptor expression and antigen\/major histoeompatibility complex-driven signaling in the absence of CD3 \u03b6 and CD3 \u03b7","volume":"266","author":"Rodewald","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1540","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0092-8674(92)90125-V","article-title":"A population of early fetal thymocytes expressing Fc\u03b3RII\/III contains precursors of T lymphocytes and natural killer cells","volume":"69","author":"Rodewald","year":"1992","journal-title":"Cell (Cambridge, Mass.)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1545","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1084\/jem.177.4.1079","article-title":"Fc\u03b3RII\/III and CD2 expression mark distinct subpopulations of immature CD4\u2212CD8\u2212 murine thymocytes: In vivo development kinetics and T cell receptor \u03b2 chain rearrangement status","volume":"177","author":"Rodewald","year":"1993","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1550","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.1002\/j.1460-2075.1994.tb06743.x","article-title":"Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization","volume":"13","author":"Rodewald","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1555","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/1074-7613(95)90116-7","article-title":"Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo","volume":"3","author":"Rodewald","year":"1995","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1560","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1126\/science.271.5250.818","article-title":"Identification of a committed precursor for the mast cell lineage","volume":"271","author":"Rodewald","year":"1996","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1565","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S1074-7613(00)80329-5","article-title":"Prothymocyte expansion by c-kit and the common cytokine receptor \u03b3 chain is essential for repertoire formation","volume":"6","author":"Rodewald","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1570","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1002\/eji.1830211044","article-title":"The e-kit-encoded typrosine kinase regulates the proliferation of early pre-B cells","volume":"21","author":"Rolink","year":"1991","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1575","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1084\/jem.178.4.1263","article-title":"Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci","volume":"178","author":"Rolink","year":"1993","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_rf1580","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1084\/jem.183.1.187","article-title":"A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors","volume":"183","author":"Rolink","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1585","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1038\/364798a0","article-title":"Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes","volume":"364","author":"Rothe","year":"1993","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1590","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1002\/eji.1830250735","article-title":"A 6 integrins participate in pro-T cell homing to the thymus","volume":"25","author":"Ruiz","year":"1995","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1595","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0065-2660(08)60549-0","article-title":"Hereditary anemias of the mouse: A review for geneticists","volume":"20","author":"Russell","year":"1979","journal-title":"Adv. Genet."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1600","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/eji.1830240144","article-title":"Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4","volume":"24","author":"Sadlack","year":"1994","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1605","doi-asserted-by":"crossref","first-page":"666","DOI":"10.4049\/jimmunol.158.2.666","article-title":"B220 expression by T lymphoid progenitor cells in mouse fetal liver","volume":"158","author":"Sagara","year":"1997","journal-title":"J. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1610","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1126\/science.7973703","article-title":"Analysis and expression of a cloned pre-T cell receptor gene","volume":"266","author":"Saint-Ruf","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1615","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/315765a0","article-title":"Expression of genes of the T-cell antigen receptor complex in precursor thymocytes","volume":"315","author":"Samelson","year":"1985","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1620","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1084\/jem.180.2.569","article-title":"Identification of a common T\/natural killer cell progenitor in human fetal thymus","volume":"180","author":"Sanchez","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1625","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0165-2478(96)02661-2","article-title":"Developmentally regulated Fc\u03b3 receptor expression in lymphopoiesis Fc\u03b3R III (CD16) provides an ITAM motif for pro-T and pro-B cells","volume":"54","author":"Sandor","year":"1996","journal-title":"Immunol. Lett."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1630","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1084\/jem.184.6.2185","article-title":"Dendritic cell development in culture from thymic precursor cells in the absence of granulocyte\/macrophage colony-stimulating factor","volume":"184","author":"Saunders","year":"1996","journal-title":"J. Exp. 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Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1645","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1182\/blood.V90.6.2217","article-title":"CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity","volume":"90","author":"Schmits","year":"1997","journal-title":"Blood"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1650","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.1182\/blood.V82.12.3675.3675","article-title":"CD34-expressing human thymocyte precursors proliferate in response to interleukin-7 but have lost myeloid differentiation potential","volume":"82","author":"Schmitt","year":"1993","journal-title":"Blood"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1655","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/352621a0","article-title":"Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting","volume":"352","author":"Schorle","year":"1991","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_rf1660","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/338591a0","article-title":"The generation of mature T cells requires interaction of the \u03b1\u03b2T-cell receptor with major histocompatibility antigens","volume":"338","author":"Scott","year":"1989","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1665","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1126\/science.8079170","article-title":"Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages","volume":"265","author":"Scott","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1670","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S1074-7613(00)80287-3","article-title":"PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors","volume":"6","author":"Scott","year":"1997","journal-title":"Immunity"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1675","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/j.1460-2075.1995.tb07023.x","article-title":"Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells","volume":"14","author":"Serve","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1680","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1002\/j.1460-2075.1994.tb06391.x","article-title":"Expression of LIF in transgenic mice results in altered thymic epithelium and apparent interconversion of thymic and lymph node morphologies","volume":"13","author":"Shen","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1685","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/329157a0","article-title":"Transient expression of IL-2 receptor precedes the differentiation of immature thymocytes","volume":"329","author":"Shimonkevitz","year":"1987","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1690","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1093\/intimm\/6.7.995","article-title":"CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2\u2212\/\u2212 mice in the absence of TCR \u03b2 chain expression","volume":"6","author":"Shinkai","year":"1994","journal-title":"Int. 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Med."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1895","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1146\/annurev.iy.12.040194.000505","article-title":"CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development","volume":"12","author":"Trowbridge","year":"1994","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1900","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/315666a0","article-title":"Thymocyte subpopuktion enriched for progenitors with an unrearranged T-cell receptor \u03b2-chain gene","volume":"315","author":"Trowbridge","year":"1985","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1905","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/371221a0","article-title":"An early haematopoietic defect in mice lacking the transcription factor GATA-2","volume":"371","author":"Tsai","year":"1994","journal-title":"Nature (London)"},{"key":"10.1016\/S0065-2776(08)60606-9_bb1910","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.4049\/jimmunol.156.9.3233","article-title":"11\u20137 supports D-J but not V-DJ rearrangement of TCR-\u03b2 gene in fetal liver progenitor cells","volume":"156","author":"Tsuda","year":"1996","journal-title":"J. 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Cell Biol."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1960","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/ng0796-366","article-title":"Epithelial detachment due to absence of hemidesmosomes in integrin \u03b2 4 null mice","volume":"13","author":"van der Neut","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1965","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/j.1460-2075.1990.tb08210.x","article-title":"T-cell specific rearrangement of T-cell receptor \u03b2 trangenes in mice","volume":"9","author":"van Meerwijk","year":"1990","journal-title":"EMBO J."},{"key":"10.1016\/S0065-2776(08)60606-9_bb1970","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1084\/jem.182.5.1585","article-title":"The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-\u03b6 subunit","volume":"182","author":"van Oers","year":"1995","journal-title":"J. Exp. 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