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J."},{"key":"10.1016\/S0091-3057(97)00535-2_BIB144","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/0024-3205(83)90596-9","article-title":"Comparison of analgesic potencies of Mu, Delta and Kappa agonists locally applied to various CNS regions relevant to analgesia in rats","volume":"33","author":"Satoh","year":"1983","journal-title":"Life Sci."},{"key":"10.1016\/S0091-3057(97)00535-2_BIB145","first-page":"646","article-title":"Neurotoxin-induced lesions to central serotonergic, noradrenergic and dopaminergic systems modify caffeine-induced antinociception in the formalin test and locomotor stimulation in rats","volume":"277","author":"Sawynok","year":"1996","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/S0091-3057(97)00535-2_BIB146","first-page":"393","article-title":"Antinociceptive action of the SP1\u20134 tetrapeptide and of some tuftsin analogs","volume":"42","author":"Semion","year":"1990","journal-title":"Pol. J. Pharmacol. 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