{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T08:45:50Z","timestamp":1780562750630,"version":"3.54.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4733,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[2000,8]]},"DOI":"10.1016\/s0092-8674(00)00036-2","type":"journal-article","created":{"date-parts":[[2004,4,15]],"date-time":"2004-04-15T09:36:43Z","timestamp":1082021803000},"page":"303-314","source":"Crossref","is-referenced-by-count":260,"title":["Regulation of Transcription by Ubiquitination without Proteolysis"],"prefix":"10.1016","volume":"102","author":[{"given":"Peter","family":"Kaiser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Flick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curt","family":"Wittenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven I.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/S0092-8674(00)00036-2_BIB1","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0092-8674(01)80009-X","article-title":"Components and dynamics of DNA replication complexes in S. cerevisiae","volume":"91","author":"Aparicio","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB2","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0092-8674(90)90525-J","article-title":"Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy","volume":"61","author":"Cai","year":"1990","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB3","doi-asserted-by":"crossref","first-page":"7151","DOI":"10.1093\/emboj\/17.24.7151","article-title":"The ubiquitin-proteasome pathway","volume":"17","author":"Ciechanover","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB4","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1146\/annurev.cellbio.15.1.435","article-title":"SCF and Cullin\/Ring H2-based ubiquitin ligases","volume":"15","author":"Deshaies","year":"1999","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB5","series-title":"Guide to Yeast Genetics and Molecular Biology, Volume 194","author":"Guthrie","year":"1991"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB6","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.biochem.67.1.425","article-title":"The ubiquitin system","volume":"67","author":"Hershko","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB7","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0962-8924(98)01491-3","article-title":"Gettin' down with ubiquitin","volume":"9","author":"Hicke","year":"1999","journal-title":"Trends Cell Biol."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB8","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1101\/gad.13.9.1190","article-title":"Cyclin-dependent kinase and Cks\/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets","volume":"13","author":"Kaiser","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB9","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1101\/gad.12.16.2587","article-title":"Cdc34 and the F-box protein Met30 are required for degradation of the Cdk-inhibitory kinase Swe1","volume":"12","author":"Kaiser","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB10","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1126\/science.284.5414.657","article-title":"Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase","volume":"284","author":"Kamura","year":"1999","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB11","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S0092-8674(00)80435-3","article-title":"Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation","volume":"91","author":"Kaplan","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S1097-2765(00)80184-7","article-title":"SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex","volume":"4","author":"Kitagawa","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB13","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0092-8674(00)80753-9","article-title":"How the cyclin became a cyclin","volume":"97","author":"Koepp","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB14","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1101\/gad.12.5.692","article-title":"Cdc53 is a scaffold protein for multiple Cdc34\/Skp1\/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast","volume":"12","author":"Patton","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB27","unstructured":"Patton, E.E., Willems, A.R., Tang, X., Craig, K.L., Thomas, D., and Tyers, M. (1998). SCF (Skp1-Cdc53-F-box protein) complexes in cell cycle control and metabolism. Yeast Genetics and Molecular Biology Meeting (College Park, Maryland)."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB15","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1073\/pnas.82.12.4055","article-title":"Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28","volume":"82","author":"Reed","year":"1985","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB16","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1093\/emboj\/19.2.282","article-title":"Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30)complex","volume":"19","author":"Rouillon","year":"2000","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB17","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S1097-2765(01)80001-0","article-title":"The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair","volume":"3","author":"Russell","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB18","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1101\/gad.13.12.1614","article-title":"Cdc53\/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34","volume":"13","author":"Seol","year":"1999","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB19","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1126\/science.284.5414.662","article-title":"Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1","volume":"284","author":"Skowyra","year":"1999","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB20","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1101\/gad.11.1.83","article-title":"SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast","volume":"11","author":"Strahl-Bolsinger","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB21","doi-asserted-by":"crossref","first-page":"4788","DOI":"10.1128\/MCB.14.7.4788","article-title":"Cell cycle-dependent transcription of CLN2 is conferred by multiple distinct cis-acting regulatory elements","volume":"14","author":"Stuart","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB22","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0092-8674(00)80526-7","article-title":"Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs","volume":"90","author":"Tanaka","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)00036-2_BIB23","doi-asserted-by":"crossref","first-page":"6526","DOI":"10.1128\/MCB.15.12.6526","article-title":"Met30p, a yeast transcriptional inhibitor that responds to S-adenosylmethionine, is an essential protein with WD40 repeats","volume":"15","author":"Thomas","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB24","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1128\/.61.4.503-532.1997","article-title":"Metabolism of sulfur amino acids in Saccharomyces cerevisiae","volume":"61","author":"Thomas","year":"1997","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB25","first-page":"366","article-title":"Cell-free ubiquitination of cell cycle regulators in budding yeast extracts","volume":"283","author":"Verma","year":"1997","journal-title":"Methods Enzymol."},{"key":"10.1016\/S0092-8674(00)00036-2_BIB26","doi-asserted-by":"crossref","first-page":"4835","DOI":"10.1128\/MCB.15.9.4835","article-title":"Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p\/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme","volume":"15","author":"Yoon","year":"1995","journal-title":"Mol. Cell. Biol."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400000362?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400000362?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:26:30Z","timestamp":1585700790000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867400000362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["S0092867400000362"],"URL":"https:\/\/doi.org\/10.1016\/s0092-8674(00)00036-2","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2000,8]]}}}