{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T08:16:59Z","timestamp":1779351419420,"version":"3.51.4"},"reference-count":43,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2000,10,1]],"date-time":"2000-10-01T00:00:00Z","timestamp":970358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4672,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[2000,10]]},"DOI":"10.1016\/s0092-8674(00)00136-7","type":"journal-article","created":{"date-parts":[[2004,4,15]],"date-time":"2004-04-15T09:36:43Z","timestamp":1082021803000},"page":"449-456","source":"Crossref","is-referenced-by-count":214,"title":["Structural Basis for the Recognition of DNA Repair Proteins UNG2, XPA, and RAD52 by Replication Factor RPA"],"prefix":"10.1016","volume":"103","author":[{"given":"Georges","family":"Mer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexey","family":"Bochkarev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Bochkareva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lori","family":"Frappier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.James","family":"Ingles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aled M","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter J","family":"Chazin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0092-8674(00)00136-7_BIB1","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0092-8674(95)90289-9","article-title":"Mammalian DNA nucleotide excision repair reconstituted with purified protein components","volume":"80","author":"Aboussekhra","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1021\/ar00028a001","article-title":"Methodological advances in protein NMR","volume":"26","author":"Bax","year":"1993","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB3","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/385176a0","article-title":"Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA","volume":"385","author":"Bochkarev","year":"1997","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB4","doi-asserted-by":"crossref","first-page":"4498","DOI":"10.1093\/emboj\/18.16.4498","article-title":"The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding","volume":"18","author":"Bochkarev","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB5","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.1074\/jbc.273.7.3932","article-title":"The rpa32 subunit of human replication protein A contains a single-stranded DNA-binding domain","volume":"273","author":"Bochkareva","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB6","doi-asserted-by":"crossref","first-page":"15116","DOI":"10.1021\/bi991755p","article-title":"Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327","volume":"38","author":"Buchko","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB7","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/349538a0","article-title":"Requirement for the replication protein SSB in human DNA excision repair","volume":"349","author":"Coverley","year":"1991","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB8","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1101\/gad.12.16.2598","article-title":"DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair","volume":"12","author":"De Laat","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB9","doi-asserted-by":"crossref","first-page":"27492","DOI":"10.1074\/jbc.273.42.27492","article-title":"Replication protein A stimulates long patch DBA base excision repair","volume":"273","author":"DeMott","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB10","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/BF02192866","article-title":"Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints","volume":"1","author":"G\u00fcntert","year":"1991","journal-title":"J. Biomol. NMR"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB11","doi-asserted-by":"crossref","first-page":"4400","DOI":"10.1128\/MCB.18.7.4400","article-title":"Studies of the interaction between RAD52 protein and the yeast single-stranded DNA binding protein RPA","volume":"18","author":"Hays","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB12","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/374566a0","article-title":"RPA involvement in the damage-recognition and incision steps of nucleotide excision repair","volume":"374","author":"He","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB13","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1006\/jmbi.1993.1489","article-title":"Protein structure comparison by alignment of distance matrices","volume":"233","author":"Holm","year":"1993","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1080\/10409239991209255","article-title":"Replication protein A (RPA)","volume":"34","author":"Iftode","year":"1999","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB15","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/1400","article-title":"Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA","volume":"5","author":"Ikegami","year":"1998","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB16","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1021\/ja00033a019","article-title":"Isotope-filtered 2D NMR of a protein-peptide complex","volume":"114","author":"Ikura","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0263-7855(96)00009-4","article-title":"MOLMOL","volume":"14","author":"Koradi","year":"1996","journal-title":"J. Mol. Graphics"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB18","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S1016-8478(23)13528-X","article-title":"Functional studies on the interaction between human replication protein A and Xeroderma pigmentosum group A complementing protein (XPA)","volume":"9","author":"Lee","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB19","doi-asserted-by":"crossref","first-page":"7884","DOI":"10.1128\/MCB.14.12.7884","article-title":"Replication factor A is required in vivo for DNA replication, repair, and recombination","volume":"14","author":"Longhese","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB20","unstructured":"Macke, T., and Case, D.A. (1998). Modeling Unusual Nucleic Acid Structures, N.B. Leontes and J. Santalucia, Jr., eds. (Washington, DC: American Chemical Society), pp. 379\u2013393."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB21","doi-asserted-by":"crossref","first-page":"11047","DOI":"10.1074\/jbc.271.19.11047","article-title":"Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease","volume":"271","author":"Matsunaga","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB22","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1023\/A:1008306832408","article-title":"1H15N and 13C resonance assignments for the C-terminal protein interaction region of the 32 kDa subunit of human replication protein A","volume":"17","author":"Mer","year":"2000","journal-title":"J. Biomol. NMR"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB23","doi-asserted-by":"crossref","first-page":"12182","DOI":"10.1016\/S0021-9258(19)49821-9","article-title":"Mutational analysis of the structure and function of the xeroderma pigmentosum group A complementing protein","volume":"267","author":"Miyamoto","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB24","doi-asserted-by":"crossref","first-page":"6561","DOI":"10.1074\/jbc.272.10.6561","article-title":"A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A","volume":"272","author":"Nagelhus","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB25","first-page":"166","article-title":"GRASP","volume":"64","author":"Nicholls","year":"1993","journal-title":"Biophys. J."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB26","doi-asserted-by":"crossref","first-page":"3834","DOI":"10.1093\/emboj\/18.13.3834","article-title":"Post-replicative base excision repair in replication foci","volume":"18","author":"Otterlei","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB27","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S0033583500005412","article-title":"Heteronuclear filters in two-dimensional [1H,1H]-NMR spectroscopy","volume":"23","author":"Otting","year":"1990","journal-title":"Quat. Rev. Biophys."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB28","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0959-440X(99)80006-2","article-title":"Envisioning the molecular choreography of DNA base excision repair","volume":"9","author":"Parikh","year":"1999","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB29","doi-asserted-by":"crossref","first-page":"18996","DOI":"10.1074\/jbc.271.31.18996","article-title":"Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells","volume":"271","author":"Park","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB30","series-title":"AMBER 4.1","author":"Pearlman","year":"1995"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB31","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/362219a0","article-title":"Crystal structure of globular domain of histone H5 and its implications for nucleosome binding","volume":"362","author":"Ramakrishnan","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB32","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1093\/nar\/24.23.4719","article-title":"Sequential binding of DNA repair proteins RPA and ERCC1 to XPA in vitro","volume":"24","author":"Saijo","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB33","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1146\/annurev.bi.65.070196.000355","article-title":"DNA excision repair","volume":"65","author":"Sancar","year":"1996","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB34","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/(SICI)1097-0282(199603)38:3<305::AID-BIP4>3.0.CO;2-Y","article-title":"Reduced surface","volume":"38","author":"Sanner","year":"1996","journal-title":"Biopolymers"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB35","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0014-5793(89)80027-4","article-title":"Stereospecific assignment of the methyl 1H NMR lines of valine and leucine in polypeptides by nonrandom 13C labelling","volume":"249","author":"Senn","year":"1989","journal-title":"FEBS Lett."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB36","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1046\/j.1365-2443.1998.00176.x","article-title":"Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing","volume":"3","author":"Shinohara","year":"1998","journal-title":"Genes Cells"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB37","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/384087a0","article-title":"A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA","volume":"384","author":"Slupphaug","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB38","doi-asserted-by":"crossref","first-page":"9337","DOI":"10.1074\/jbc.273.15.9337","article-title":"Functional analysis of human replication protein A in nucleotide excision repair","volume":"273","author":"Stigger","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB39","doi-asserted-by":"crossref","first-page":"6049","DOI":"10.1073\/pnas.95.11.6049","article-title":"DNA annealing by Rad52 protein is stimulated by specific interaction with the complex of replication protein A and single-stranded DNA","volume":"95","author":"Sugiyama","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB40","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1146\/annurev.biochem.66.1.61","article-title":"Replication protein A","volume":"66","author":"Wold","year":"1997","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB41","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/35003614","article-title":"Single-molecule studies of the effect of template tension on T7 DNA polymerase activity","volume":"404","author":"Wuite","year":"2000","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)00136-7_BIB42","doi-asserted-by":"crossref","first-page":"6189","DOI":"10.1093\/emboj\/18.21.6189","article-title":"Multiple competition rections for RPA order the assembly of the DNA polymerase \u03b4 holoenzyme","volume":"18","author":"Yuzhakov","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)00136-7_BIB43","doi-asserted-by":"crossref","first-page":"6711","DOI":"10.1021\/ja970224q","article-title":"Methods for measurement of intermolecular NOEs by multinuclear NMR spectroscopy","volume":"119","author":"Zwalen","year":"1997","journal-title":"J. Am. Chem. Soc."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400001367?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400001367?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T21:11:57Z","timestamp":1734297117000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867400001367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,10]]}},"alternative-id":["S0092867400001367"],"URL":"https:\/\/doi.org\/10.1016\/s0092-8674(00)00136-7","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2000,10]]}}}