{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:09:41Z","timestamp":1779343781840,"version":"3.51.4"},"reference-count":47,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[1997,12,1]],"date-time":"1997-12-01T00:00:00Z","timestamp":880934400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":5707,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[1997,12]]},"DOI":"10.1016\/s0092-8674(00)80485-7","type":"journal-article","created":{"date-parts":[[2004,4,10]],"date-time":"2004-04-10T09:39:29Z","timestamp":1081589969000},"page":"939-947","source":"Crossref","is-referenced-by-count":98,"title":["PDZ-like Domains Mediate Binding Specificity in the Clp\/Hsp100 Family of Chaperones and Protease Regulatory Subunits"],"prefix":"10.1016","volume":"91","author":[{"given":"Igor","family":"Levchenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine K","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan P","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert T","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania A","family":"Baker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0092-8674(00)80485-7_BIB1","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/0092-8674(93)90519-V","article-title":"Division of labor among monomers within the Mu transposase tetramer","volume":"74","author":"Baker","year":"1993","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB2","doi-asserted-by":"crossref","first-page":"6070","DOI":"10.1073\/pnas.94.12.6070","article-title":"Crystal structure of heat shock locus V (HslV) from Escherichia coli","volume":"94","author":"Bochtler","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB3","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/382649a0","article-title":"Crystal structure of a PDZ domain","volume":"382","author":"Cabral","year":"1996","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB4","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0014-5793(75)80160-8","article-title":"Pulse methods for the simplification of protein NMR spectra","volume":"57","author":"Campbell","year":"1975","journal-title":"FEBS Lett."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB5","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1126\/science.7754373","article-title":"Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]","volume":"268","author":"Chernoff","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB6","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0896-6273(92)90245-9","article-title":"The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein","volume":"9","author":"Cho","year":"1992","journal-title":"Neuron"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB7","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00197809","article-title":"NMRPIPE","volume":"6","author":"Delaglio","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB8","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S0092-8674(00)80502-4","article-title":"Cell type-specific phosphorylation and proteolysis of a transcriptional regulator controls the G1-to-S transition in a bacterial cell cycle","volume":"90","author":"Domian","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB9","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/S0092-8674(00)81307-0","article-title":"Crystal structures of a complexed and peptide-free membrane protein-binding domain","volume":"85","author":"Doyle","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB10","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/S0960-9822(96)00737-3","article-title":"Protein-protein interactions","volume":"6","author":"Fanning","year":"1996","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB11","doi-asserted-by":"crossref","first-page":"5984","DOI":"10.1021\/bi00185a040","article-title":"Backbone dynamics of a free and a phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation","volume":"33","author":"Farrow","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB12","doi-asserted-by":"crossref","first-page":"10291","DOI":"10.1073\/pnas.93.19.10291","article-title":"Regulation of SOS mutagenesis by proteolysis","volume":"9","author":"Frank","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB46","doi-asserted-by":"crossref","first-page":"6578","DOI":"10.1128\/jb.173.20.6578-6585.1991","article-title":"Frameshift mutations in the bacteriophage Mu repressor gene can confer a trans-dominant virulent phenotype to the phage","volume":"173","author":"Geuskens","year":"1991","journal-title":"J. Bacteriol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB13","doi-asserted-by":"crossref","first-page":"5121","DOI":"10.1002\/j.1460-2075.1992.tb05619.x","article-title":"Virulence in bacteriophage Mu","volume":"11","author":"Geuskens","year":"1992","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB14","doi-asserted-by":"crossref","first-page":"22618","DOI":"10.1016\/S0021-9258(18)41573-6","article-title":"ClpX, an alternative subunit for ATP-dependent Clp protease of E. coli","volume":"268","author":"Gottesman","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0092-8674(00)80105-1","article-title":"Peptide-surface association","volume":"86","author":"Harrison","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB16","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1126\/science.277.5331.1511","article-title":"Binding of neuroligins to PSD-95","volume":"277","author":"Irie","year":"1997","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB17","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1126\/science.271.5251.990","article-title":"Role of a peptide tagging system in degradation of protein synthesized from damaged messenger RNA","volume":"271","author":"Keiler","year":"1996","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB18","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1006\/jmbi.1995.0400","article-title":"Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome","volume":"250","author":"Kessel","year":"1995","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB19","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1002\/j.1460-2075.1996.tb00428.x","article-title":"ClpX protein of Escherichia coli activates bacteriophage Mu transposase in the strand transfer complex for initiation of Mu DNA synthesis","volume":"15","author":"Kruklitis","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB20","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/j.1460-2075.1996.tb00374.x","article-title":"Bacteriophage Mu repressor as a target for the E. coli ATP-dependent Clp protease","volume":"15","author":"Laachouch","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB21","doi-asserted-by":"crossref","first-page":"3274","DOI":"10.1073\/pnas.92.8.3274","article-title":"Addiction protein Phd of plasmid prophage P1 is a substrate of ClpXP serine protease of Escherichia coli","volume":"92","author":"Lehnherr","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB22","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1101\/gad.9.19.2399","article-title":"Disassembly of the Mu transposase tetramer by the ClpX chaperone","volume":"9","author":"Levchenko","year":"1995","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB23","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1101\/gad.11.12.1561","article-title":"ClpX and MuB interact with overlapping regions of Mu transposase","volume":"11","author":"Levchenko","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB24","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1111\/j.1365-2958.1994.tb00387.x","article-title":"A new component of bacteriophage Mu replicative transposition machinery","volume":"11","author":"Mhammedi-Alaoui","year":"1994","journal-title":"Mol. Microbiol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB25","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1002\/pro.5560021219","article-title":"P22 Arc repressor","volume":"2","author":"Milla","year":"1993","journal-title":"Protein Sci."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB26","doi-asserted-by":"crossref","first-page":"19591","DOI":"10.1074\/jbc.270.33.19591","article-title":"Disassembly of the bacteriophage Mu transposase for the initiation of Mu DNA replication","volume":"270","author":"Nakai","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB27","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/353270a0","article-title":"Hsp104 is a highly conserved protein with two essential nucleotide-binding sites","volume":"353","author":"Parsell","year":"1991","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB28","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/372475a0","article-title":"Protein disaggregation mediated by heat-shock protein Hsp104","volume":"372","author":"Parsell","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB29","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1002\/pro.5560060225","article-title":"Evidence for PDZ domains in bacteria, yeast, and plants","volume":"6","author":"Ponting","year":"1997","journal-title":"Protein Sci."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB30","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nsb0597-342","article-title":"Interaction of Hsp70 chaperones with substrates","volume":"4","author":"R\u00fcdiger","year":"1997","journal-title":"Nature Struct. Biol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB31","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S0968-0004(96)30044-3","article-title":"PDZ domains bind carboxy-terminal sequences of target proteins","volume":"21","author":"Saras","year":"1996","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB32","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0968-0004(96)10038-4","article-title":"Hsp100\/Clp proteins","volume":"21","author":"Schirmer","year":"1996","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB33","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1128\/jb.178.2.470-476.1996","article-title":"Regulation of Escherichia coli starvation sigma factor (\u03c3s) by ClpXP protease","volume":"178","author":"Schweder","year":"1996","journal-title":"J. Bacteriol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB34","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1016\/S0896-6273(00)80122-1","article-title":"Regulation of the TRP Ca2+ channel by INAD in Drosophila photoreceptors","volume":"16","author":"Shieh","year":"1996","journal-title":"Neuron"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB35","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1006\/jmrb.1993.1095","article-title":"Practical aspects of two-dimensional proton-detected 15N spin relaxation methods","volume":"102","author":"Skelton","year":"1993","journal-title":"J. Mag. Res. Ser. B"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB47","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1126\/science.275.5296.73","article-title":"Recognition of unique carboxyl-terminal motifs by distinct PDZ domains","volume":"275","author":"Songyang","year":"1997","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB36","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0092-8674(87)90566-6","article-title":"Transpososomes","volume":"49","author":"Surette","year":"1987","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB37","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1126\/science.1962196","article-title":"The N-end rule in bacteria","volume":"254","author":"Tobias","year":"1991","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB38","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/40805","article-title":"A multivalent PDZ-domain protein assembles signaling complexes in a G-protein-coupled cascade","volume":"388","author":"Tsunoda","year":"1997","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB39","doi-asserted-by":"crossref","first-page":"9322","DOI":"10.1074\/jbc.270.16.9322","article-title":"C-terminal extension of truncated recombinant proteins in Escherichia coli with a 10Sa RNA decapeptide","volume":"270","author":"Tu","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB40","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S0960-9822(95)00061-3","article-title":"Heat-shock proteins Hsp104 and Hsp70 reactivate mRNA splicing after heat inactivation","volume":"5","author":"Vogel","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB41","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1002\/j.1460-2075.1995.tb07179.x","article-title":"The ClpX heat-shock protein of Escherichia coli, the ATP-dependent substrate specificity component of the ClpP-ClpX protease, is a novel molecular chaperone","volume":"14","author":"Wawrzynow","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB42","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1021\/bi00377a033","article-title":"1H NMR aromatic spectrum of the operator binding domain of the lambda repressor","volume":"26","author":"Weiss","year":"1987","journal-title":"Biochemistry"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB43","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/jmbi.1997.1193","article-title":"Communication of ClpXP protease hypersensitivity to bacteriophage Mu repressor isoforms","volume":"272","author":"Welty","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0092-8674(00)80485-7_BIB44","doi-asserted-by":"crossref","first-page":"12218","DOI":"10.1073\/pnas.91.25.12218","article-title":"A molecular chaperone, ClpA, functions like DnaK and DnaJ","volume":"91","author":"Wickner","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)80485-7_BIB45","doi-asserted-by":"crossref","first-page":"22609","DOI":"10.1016\/S0021-9258(18)41572-4","article-title":"Isolation and characterization of ClpX, a new ATP-dependent specificity component of ClpP protease of E. coli.","volume":"268","author":"Wojtkowiak","year":"1993","journal-title":"J. Biol. Chem."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400804857?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400804857?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T13:48:31Z","timestamp":1623764911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867400804857"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,12]]},"references-count":47,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1997,12]]}},"alternative-id":["S0092867400804857"],"URL":"https:\/\/doi.org\/10.1016\/s0092-8674(00)80485-7","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[1997,12]]}}}