{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:20:51Z","timestamp":1779344451932,"version":"3.51.4"},"reference-count":50,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[1996,3,1]],"date-time":"1996-03-01T00:00:00Z","timestamp":825638400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":6347,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[1996,3]]},"DOI":"10.1016\/s0092-8674(00)81049-1","type":"journal-article","created":{"date-parts":[[2004,4,10]],"date-time":"2004-04-10T05:39:29Z","timestamp":1081575569000},"page":"711-722","source":"Crossref","is-referenced-by-count":222,"title":["Identification of an Asymmetrically Localized Determinant, Ash1p, Required for Lineage-Specific Transcription of the Yeast HO Gene"],"prefix":"10.1016","volume":"84","author":[{"given":"Anita","family":"Sil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira","family":"Herskowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0092-8674(00)81049-1_BIB1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0092-8674(89)90168-2","article-title":"Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene","volume":"57","author":"Andrews","year":"1989","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB2","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1126\/science.270.5236.637","article-title":"Localization of protein implicated in establishment of cell type to sites of asymmetric division","volume":"270","author":"Arigoni","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB50","doi-asserted-by":"crossref","DOI":"10.1016\/S0092-8674(00)81048-X","article-title":"Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells","volume":"84","author":"Bobola","year":"1996","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB3","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0092-8674(87)90190-5","article-title":"Cell cycle control of the yeast HO gene","volume":"48","author":"Breeden","year":"1987","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB4","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/0092-8674(91)90015-Q","article-title":"Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway","volume":"65","author":"Chant","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB5","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1083\/jcb.129.3.751","article-title":"Patterns of bud-site selection in the yeast Saccharomyces cerevisiae","volume":"129","author":"Chant","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB6","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/0092-8674(91)90394-E","article-title":"A potential positive feedback loop controlling CLN1 and CLN2 gene expression at the start of the yeast cell cycle","volume":"65","author":"Cross","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB7","doi-asserted-by":"crossref","first-page":"6205","DOI":"10.1128\/MCB.11.12.6205","article-title":"Expression of the DAL80 gene, whose product is homologous to the GATA factors and is a negative regulator of multiple nitrogen catabolic genes in Saccharomyces cerevisiae, is sensitive to nitrogen catabolite repression","volume":"11","author":"Cunningham","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB8","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/369371a0","article-title":"Complete DNA sequence of yeast chromosome XI","volume":"369","author":"Dujon","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB9","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1126\/science.270.5236.641","article-title":"Activation of cell-specific transcription by a serine phosphatase at the site of asymmetric division","volume":"270","author":"Duncan","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB10","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0092-8674(91)90646-G","article-title":"Expression of positional information during cell differentiation in Caulobacter","volume":"64","author":"Gober","year":"1991","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB11","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/0896-6273(95)90330-5","article-title":"tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS","volume":"14","author":"Guo","year":"1995","journal-title":"Neuron"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB12","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.1093\/nar\/18.13.4025","article-title":"Nucleotide sequence of the Saccharomyces cerevisiae CLN1 and CLN2 genes","volume":"18","author":"Hadwiger","year":"1990","journal-title":"Nucl. Acids Res."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB13","doi-asserted-by":"crossref","first-page":"6255","DOI":"10.1073\/pnas.86.16.6255","article-title":"A family of cyclin homologs that control the G1 phase in yeast","volume":"86","author":"Hadwiger","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB14","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1073\/pnas.83.5.1418","article-title":"Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone \u03b1-factor","volume":"83","author":"Hagen","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB15","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1128\/MMBR.52.4.536-553.1988","article-title":"Life cycle of the budding yeast Saccharomyces cerevisiae","volume":"52","author":"Herskowitz","year":"1988","journal-title":"Microbiol. Rev."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB16","unstructured":"Herskowitz, I., Andrews, B., Kruger, W., Ogas, J., Sil, A., Coburn, C., Peterson, C. (1992). Integration of multiple regulatory inputs in the control of HO expression in yeast. In Transcriptional Regulation, S.L. McKnight and K.R. Yamamoto, eds. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), pp. 949\u2013974."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/genetics\/83.2.245","article-title":"Interconversion of yeast mating type. I. Direct observation of the action of the homothallism (HO) gene","volume":"83","author":"Hicks","year":"1976","journal-title":"Genetics"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB18","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0092-8674(92)90468-R","article-title":"Mechanisms of asymmetric cell division","volume":"68","author":"Horvitz","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB19","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1073\/pnas.80.10.3035","article-title":"Regulation of yeast mating-type interconversion","volume":"80","author":"Jensen","year":"1983","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB20","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1038\/377624a0","article-title":"Asymmetric segregation of Numb and Prospero during cell division","volume":"377","author":"Knoblich","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB21","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/0076-6879(91)94038-E","article-title":"Epitope tagging and protein surveillance","volume":"194","author":"Kolodziej","year":"1991","journal-title":"Meth. Enzymol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB22","series-title":"Analysis of the SIN1 and SIN2 gene products and their role in transcriptional regulation in Saccharomyces cerevisiae","author":"Kruger","year":"1991"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB23","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1101\/gad.5.12b.2405","article-title":"A new role for MCM1 in yeast","volume":"5","author":"Lydall","year":"1991","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB24","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/0092-8674(83)90553-6","article-title":"Pedigree analysis of plasmid segregation in yeast","volume":"34","author":"Murray","year":"1983","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB25","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1002\/j.1460-2075.1985.tb03982.x","article-title":"Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae","volume":"4","author":"Nakayama","year":"1985","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB26","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1038\/302670a0","article-title":"Molecular analysis of a cell lineage","volume":"302","author":"Nasmyth","year":"1983","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB27","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0092-8674(85)80118-5","article-title":"A repetitive DNA sequence that confers cell-cycle START (CDC28)-dependent transcription of the HO gene in yeast","volume":"42","author":"Nasmyth","year":"1985","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB28","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/j.1460-2075.1987.tb04745.x","article-title":"The determination of mother cell-specific mating type switching in yeast by a specific regulator of HO transcription","volume":"6","author":"Nasmyth","year":"1987","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB29","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/0959-437X(93)90036-O","article-title":"Regulating the HO endonuclease in yeast","volume":"3","author":"Nasmyth","year":"1993","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB30","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1126\/science.3306917","article-title":"Transcriptional regulation of the yeast life cycle","volume":"237","author":"Nasmyth","year":"1987","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB31","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/0092-8674(87)90457-0","article-title":"Cell cycle regulation of SWI5 is required for mother-cell-specific HO transcription in yeast","volume":"49","author":"Nasmyth","year":"1987","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB32","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/0092-8674(87)90236-4","article-title":"Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast","volume":"48","author":"Nasmyth","year":"1987","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB33","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/0092-8674(90)90110-Z","article-title":"The identification of a second cell cycle control on the HO promoter in yeast","volume":"62","author":"Nasmyth","year":"1990","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB34","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1182\/blood.V80.3.575.575","article-title":"GATA-binding transcription factors in hematopoietic cells","volume":"80","author":"Orkin","year":"1992","journal-title":"Blood"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB35","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/0076-6879(91)94043-C","article-title":"Immunofluorescence methods for yeast","volume":"194","author":"Pringle","year":"1991","journal-title":"Meth. Enzymol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB36","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1242\/dev.119.4.1277","article-title":"pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1","volume":"119","author":"Ramain","year":"1993","journal-title":"Development"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB37","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/0092-8674(94)90112-0","article-title":"Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells","volume":"76","author":"Rhyu","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB38","series-title":"Methods in Yeast Genetics","author":"Rose","year":"1990"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB39","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0076-6879(91)94022-5","article-title":"Targetting, disruption, replacement, and allele rescue","volume":"194","author":"Rothstein","year":"1991","journal-title":"Meth. Enzymol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB40","series-title":"Molecular Cloning","author":"Sambrook","year":"1989"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB41","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1128\/JB.155.1.8-14.1983","article-title":"Nucleotide sequence of the TCM1 gene (ribosomal protein L3) of Saccharomyces cerevisiae","volume":"155","author":"Schultz","year":"1983","journal-title":"J. Bacteriol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB42","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1101\/gad.7.7a.1160","article-title":"CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae","volume":"7","author":"Schwob","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB43","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/genetics\/122.1.19","article-title":"A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae","volume":"122","author":"Sikorski","year":"1989","journal-title":"Genetics"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB44","unstructured":"Stern, M. (1985). Genes controlling the expression of the HO gene in yeast. PhD thesis, University of California, San Francisco, San Francisco, California."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB45","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/0022-2836(84)90315-2","article-title":"Five SWI genes are required for expression of the HO gene in yeast","volume":"178","author":"Stern","year":"1984","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB46","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0092-8674(87)90235-2","article-title":"Activation of the yeast HO gene by release from multiple negative controls","volume":"48","author":"Sternberg","year":"1987","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB47","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0092-8674(79)90163-6","article-title":"Asymmetry and directionality in production of new cell types during clonal growth","volume":"17","author":"Strathern","year":"1979","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81049-1_BIB48","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1101\/gad.7.3.517","article-title":"SWI5 instability may be necessary but is not sufficient for asymmetric HO expression in yeast","volume":"7","author":"Tebb","year":"1993","journal-title":"Genes Dev."},{"key":"10.1016\/S0092-8674(00)81049-1_BIB49","doi-asserted-by":"crossref","first-page":"7091","DOI":"10.1128\/MCB.13.11.7091","article-title":"urbs1, a gene regulating siderophore biosynthesis in Ustilago maydis, encodes a protein similar to the erythroid transcription factor GATA-1","volume":"13","author":"Voisard","year":"1993","journal-title":"Mol. Cell. Biol."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400810491?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867400810491?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T09:53:59Z","timestamp":1623750839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867400810491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,3]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1996,3]]}},"alternative-id":["S0092867400810491"],"URL":"https:\/\/doi.org\/10.1016\/s0092-8674(00)81049-1","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717949645.793454907","asserted-by":"object"}]},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[1996,3]]}}}