{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:33:31Z","timestamp":1779341611357,"version":"3.51.4"},"reference-count":61,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1996,5,1]],"date-time":"1996-05-01T00:00:00Z","timestamp":830908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":6286,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell"],"published-print":{"date-parts":[[1996,5]]},"DOI":"10.1016\/s0092-8674(00)81257-x","type":"journal-article","created":{"date-parts":[[2004,6,9]],"date-time":"2004-06-09T20:23:03Z","timestamp":1086812583000},"page":"573-583","source":"Crossref","is-referenced-by-count":260,"title":["The 70 kDa S6 Kinase Complexes with and Is Activated by the Rho Family G Proteins Cdc42 and Rac1"],"prefix":"10.1016","volume":"85","author":[{"given":"Margaret M","family":"Chou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Blenis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0092-8674(00)81257-X_BIB1","doi-asserted-by":"crossref","first-page":"27995","DOI":"10.1074\/jbc.270.47.27995","article-title":"Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation","volume":"270","author":"Bagrodia","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB2","doi-asserted-by":"crossref","first-page":"26059","DOI":"10.1016\/S0021-9258(19)74277-X","article-title":"Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain","volume":"268","author":"Barfod","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB3","doi-asserted-by":"crossref","first-page":"9231","DOI":"10.1073\/pnas.87.23.9231","article-title":"Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin","volume":"87","author":"Bierer","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB4","first-page":"279","article-title":"Distinct mechanisms for the activation of the RSK kinases\/MAP2 kinase\/pp90rsk and pp70 S6 kinase signaling systems are indicated by inhibition of protein synthesis","volume":"2","author":"Blenis","year":"1991","journal-title":"Cell Growth Differ."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB5","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/369756a0","article-title":"A mammalian protein targeted by G1-arresting rapamycin-receptor complex","volume":"369","author":"Brown","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB6","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/377441a0","article-title":"Control of p70 S6 kinase by kinase activity of FRAP in vivo","volume":"377","author":"Brown","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB7","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/376599a0","article-title":"Protein kinase B (c-akt) in phosphatidylinositol 3-OH kinase signal transduction","volume":"376","author":"Burgering","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB8","doi-asserted-by":"crossref","first-page":"7571","DOI":"10.1073\/pnas.89.16.7571","article-title":"Interleukin 2 stimulation of p70 S6 kinase is inhibited by the immunosuppressant rapamycin","volume":"89","author":"Calvo","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB9","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0968-0004(00)88978-1","article-title":"Parallel signal processing among mammalian MAPKs","volume":"20","author":"Cano","year":"1995","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB10","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1128\/MCB.14.7.4902","article-title":"Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation","volume":"14","author":"Cheatham","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB11","doi-asserted-by":"crossref","first-page":"11696","DOI":"10.1073\/pnas.92.25.11696","article-title":"Structural and functional analysis of pp70S6k","volume":"92","author":"Cheatham","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB12","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/0955-0674(95)80064-6","article-title":"The 70 kD S6 kinase","volume":"7","author":"Chou","year":"1995","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB13","doi-asserted-by":"crossref","first-page":"5834","DOI":"10.1128\/MCB.12.12.5834","article-title":"The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels","volume":"12","author":"Chou","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB14","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/0092-8674(92)90643-Q","article-title":"Rapamycin\u2013FKBP specifically blocks growth-dependent activation of and signaling by the 70 kD S6 protein kinases","volume":"69","author":"Chung","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB15","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/370071a0","article-title":"PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol 3-OH kinase","volume":"370","author":"Chung","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB16","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/S0092-8674(05)80018-2","article-title":"The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK\/SAPK signaling pathway","volume":"81","author":"Coso","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB17","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1126\/science.7839144","article-title":"Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms","volume":"267","author":"D\u00e9rijard","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1126\/science.8036496","article-title":"Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity","volume":"265","author":"Diekmann","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB19","doi-asserted-by":"crossref","first-page":"5297","DOI":"10.1002\/j.1460-2075.1995.tb00214.x","article-title":"Rac GTPase interacts with GAPs and target proteins through multiple effector sites","volume":"14","author":"Diekmann","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB20","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4049\/jimmunol.144.1.251","article-title":"Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK506 and rapamycin","volume":"144","author":"Dumont","year":"1990","journal-title":"J. Immunol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB21","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/316273a0","article-title":"Isolation of a new human oncogene from a diffuse B-cell lymphoma","volume":"316","author":"Eva","year":"1985","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB22","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3109\/10409239409083485","article-title":"S6 phosphorylation and the p70S6k\/p85S6k","volume":"29","author":"Ferrari","year":"1994","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB23","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/0092-8674(95)90534-0","article-title":"The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase","volume":"81","author":"Franke","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB24","doi-asserted-by":"crossref","first-page":"21396","DOI":"10.1074\/jbc.270.36.21396","article-title":"Rapamycin, wortmannin, and methylxanthine SQ20006 inactivate p70S6k by inducing dephosphorylation of the same subset of sites","volume":"270","author":"Han","year":"1995","journal-title":"J. Biol. Chem"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB25","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0092-8674(90)90294-O","article-title":"A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane","volume":"63","author":"Hancock","year":"1990","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB26","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/354311a0","article-title":"Catalysis of guanine nucleotide exchange on the Cdc42Hs protein by the dbl oncogene product","volume":"354","author":"Hart","year":"1991","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB27","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0021-9258(17)42313-1","article-title":"Cell transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product","volume":"269","author":"Hart","year":"1994","journal-title":"J. Biol. Chem"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB28","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0960-9822(95)00080-7","article-title":"PDGF stimulates an increase in Rac\u2013GTP via the activation of phosphoinositide 3-kinase","volume":"5","author":"Hawkins","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB29","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0092-8674(05)80020-0","article-title":"The Rho family GTPases RhoA, Rac1, and Cdc42Hs regulate transcriptional activation by SRF","volume":"81","author":"Hill","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB30","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1128\/MCB.15.4.1942","article-title":"The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts","volume":"15","author":"Kozma","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB31","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/358070a0","article-title":"Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase","volume":"358","author":"Kuo","year":"1992","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB32","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/363170a0","article-title":"p70S6k function is essential for G1 progression","volume":"363","author":"Lane","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB33","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/363364a0","article-title":"A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42","volume":"363","author":"Manser","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB34","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/367040a0","article-title":"A brain serine\/threonine kinase activated by Cdc42 and Rac1","volume":"367","author":"Manser","year":"1994","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB35","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1126\/science.7992057","article-title":"Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK","volume":"266","author":"Minden","year":"1994","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB36","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/S0092-8674(05)80019-4","article-title":"Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42 Hs","volume":"81","author":"Minden","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB37","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1128\/MCB.15.1.326","article-title":"Activation of p70\/p85 S6 kinases in interleukin-2\u2013responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP","volume":"15","author":"Monfar","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB38","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0021-9258(18)54107-7","article-title":"Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate","volume":"268","author":"Nakanishi","year":"1993","journal-title":"J. Biol. Chem"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB39","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0092-8674(95)90370-4","article-title":"Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia","volume":"81","author":"Nobes","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB40","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1242\/jcs.108.1.225","article-title":"Activation of the small GTP-binding proteins rho and rac by growth factor receptors","volume":"108","author":"Nobes","year":"1995","journal-title":"J. Cell Sci."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB41","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1126\/science.7652575","article-title":"An esential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1","volume":"269","author":"Olson","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB42","doi-asserted-by":"crossref","first-page":"5279","DOI":"10.1002\/j.1460-2075.1995.tb00212.x","article-title":"The principal target of rapamycin-induced p70S6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain","volume":"14","author":"Pearson","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB43","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1126\/science.1380182","article-title":"Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase","volume":"257","author":"Price","year":"1992","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB44","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/374457a0","article-title":"An essential role for Rac in Ras transformation","volume":"374","author":"Qiu","year":"1995","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB45","doi-asserted-by":"crossref","first-page":"7420","DOI":"10.1074\/jbc.270.13.7420","article-title":"Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine","volume":"270","author":"Raingeaud","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB46","first-page":"235","article-title":"Differential regulation of the p72\u201374 Raf-1 kinase in 3T3 fibroblasts expressing ras or src oncogenes","volume":"2","author":"Reed","year":"1991","journal-title":"Cell Growth Differ."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB47","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1002\/j.1460-2075.1994.tb06418.x","article-title":"Nuclear localization of p85S6k","volume":"13","author":"Reinhard","year":"1994","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB48","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0092-8674(92)90163-7","article-title":"The small GTP-binding protein Rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors","volume":"70","author":"Ridley","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB49","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0092-8674(92)90164-8","article-title":"The small GTP-binding protein Rac regulates growth factor\u2013induced membrane ruffling","volume":"70","author":"Ridley","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB50","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0092-8674(94)90570-3","article-title":"RAFT1","volume":"78","author":"Sabatini","year":"1994","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB51","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1074\/jbc.270.2.815","article-title":"Isolation of a protein target of the FKBP12\u2013rapamycin complex in mammalian cells","volume":"270","author":"Sabers","year":"1995","journal-title":"J. Biol. Chem"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB52","first-page":"655","article-title":"Different structural organization of Ras and Rho effector domains","volume":"8","author":"Self","year":"1993","journal-title":"Oncogene"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB53","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1084\/jem.167.3.1259","article-title":"Thymic lymphoma induction by the AKT8 murine retrovirus","volume":"167","author":"Staal","year":"1988","journal-title":"J. Exp. Med."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB54","doi-asserted-by":"crossref","first-page":"32358","DOI":"10.1016\/S0021-9258(18)31643-0","article-title":"Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3","volume":"269","author":"Toker","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB55","doi-asserted-by":"crossref","first-page":"17656","DOI":"10.1074\/jbc.270.30.17656","article-title":"Rho family GTPases bind to phosphoinositide kinases","volume":"270","author":"Tolias","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(00)81257-X_BIB56","doi-asserted-by":"crossref","first-page":"5744","DOI":"10.1073\/pnas.92.12.5744","article-title":"Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation","volume":"92","author":"Weng","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB57","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1126\/science.7618106","article-title":"Integration of MAP kinase signal transduction pathways at the serum response element","volume":"269","author":"Whitmarsh","year":"1995","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB58","doi-asserted-by":"crossref","first-page":"2922","DOI":"10.1073\/pnas.89.7.2922","article-title":"Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate Raf-1 kinase","volume":"89","author":"Williams","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB59","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1126\/science.2115210","article-title":"Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1","volume":"249","author":"Zhang","year":"1990","journal-title":"Science"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB60","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/364308a0","article-title":"Normal and oncogenic p21ras proteins bind to the amino-terminal domain of c-Raf-1","volume":"364","author":"Zhang","year":"1993","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(00)81257-X_BIB61","doi-asserted-by":"crossref","first-page":"18727","DOI":"10.1016\/S0021-9258(17)32226-3","article-title":"Activation of phosphoinositide-3 kinase activity by Cdc42Hs binding to p85","volume":"269","author":"Zheng","year":"1994","journal-title":"J. Biol. Chem."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009286740081257X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009286740081257X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T20:43:30Z","timestamp":1682714610000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009286740081257X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,5]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,5]]}},"alternative-id":["S009286740081257X"],"URL":"https:\/\/doi.org\/10.1016\/s0092-8674(00)81257-x","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[1996,5]]}}}