{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:42:57Z","timestamp":1779345777692,"version":"3.51.4"},"reference-count":87,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":3819,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2003,2,1]],"date-time":"2003-02-01T00:00:00Z","timestamp":1044057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell"],"published-print":{"date-parts":[[2003,2]]},"DOI":"10.1016\/s0092-8674(03)00082-5","type":"journal-article","created":{"date-parts":[[2004,4,17]],"date-time":"2004-04-17T14:47:25Z","timestamp":1082213245000},"page":"441-451","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":589,"title":["Regulating Access to the Genome"],"prefix":"10.1016","volume":"112","author":[{"given":"Karsten","family":"Weis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0092-8674(03)00082-5_BIB1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1083\/jcb.122.1.1","article-title":"Architecture of the Xenopus nuclear pore complex revealed by three-dimensional cryo-electron microscopy","volume":"122","author":"Akey","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB2","doi-asserted-by":"crossref","first-page":"29268","DOI":"10.1074\/jbc.M102629200","article-title":"Proteomic analysis of nucleoporin interacting proteins","volume":"276","author":"Allen","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB3","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0960-9822(02)00741-8","article-title":"The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo","volume":"12","author":"Bamba","year":"2002","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB4","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0092-8674(00)00014-3","article-title":"Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking","volume":"102","author":"Bayliss","year":"2000","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB5","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1083\/jcb.152.2.411","article-title":"Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import","volume":"152","author":"Ben-Efraim","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB6","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/S0960-9822(02)00927-2","article-title":"Ran binds to chromatin by two distinct mechanisms","volume":"12","author":"Bilbao-Cortes","year":"2002","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB7","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/22133","article-title":"Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation","volume":"400","author":"Carazo-Salas","year":"1999","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB8","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/35060009","article-title":"Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly","volume":"3","author":"Carazo-Salas","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB9","doi-asserted-by":"crossref","first-page":"5874","DOI":"10.1074\/jbc.275.8.5874","article-title":"Dissecting the interactions between NTF2, RanGDP, and the nucleoporin XFXFG repeats","volume":"275","author":"Chaillan-Huntington","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB10","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/20375","article-title":"Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp","volume":"399","author":"Chook","year":"1999","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB11","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/20367","article-title":"Structure of importin-beta bound to the IBB domain of importin-alpha","volume":"399","author":"Cingolani","year":"1999","journal-title":"Nature"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB12","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/ng0901-6","article-title":"Choreographing mRNA biogenesis","volume":"29","author":"Cole","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB13","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0955-0674(00)00213-1","article-title":"Nucleocytoplasmic transport enters the atomic age","volume":"13","author":"Conti","year":"2001","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB14","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1083\/jcb.200206106","article-title":"Proteomic analysis of the mammalian nuclear pore complex","volume":"158","author":"Cronshaw","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB15","first-page":"3337","article-title":"RCC1, a regulator of mitosis, is essential for DNA replication","volume":"12","author":"Dasso","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB16","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0960-9822(02)00902-8","article-title":"Translation is required to remove Y14 from mRNAs in the cytoplasm","volume":"12","author":"Dostie","year":"2002","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB17","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/nrm760","article-title":"Messenger-RNA-binding proteins and the messages they carry","volume":"3","author":"Dreyfuss","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB18","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0960-9822(99)80044-X","article-title":"Receptor-mediated substrate translocation through the nuclear pore complex without nucleotide triphosphate hydrolysis","volume":"9","author":"Englmeier","year":"1999","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB19","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1093\/embo-reports\/kve200","article-title":"RanBP3 influences interactions between CRM1 and its nuclear protein export substrates","volume":"2","author":"Englmeier","year":"2001","journal-title":"EMBO Rep."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB20","first-page":"95","article-title":"Nuclear pore complex architecture and functional dynamics","volume":"259","author":"Fahrenkrog","year":"2001","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/0092-8674(95)90436-0","article-title":"The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs","volume":"82","author":"Fischer","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB22","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1083\/jcb.151.5.1101","article-title":"The fission yeast ran GTPase is required for microtubule integrity","volume":"151","author":"Fleig","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB23","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1146\/annurev.cellbio.15.1.607","article-title":"Transport between the cell nucleus and the cytoplasm","volume":"15","author":"G\u00f6rlich","year":"1999","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0092-8674(01)00193-3","article-title":"Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity","volume":"104","author":"Gruss","year":"2001","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB25","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/ncb870","article-title":"Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells","volume":"4","author":"Gruss","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB26","first-page":"455","article-title":"Regulated Ran-binding protein 1 activity is required for organization and function of the mitotic spindle in mammalian cells in vivo","volume":"11","author":"Guarguaglini","year":"2000","journal-title":"Cell Growth Differ."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB27","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S1097-2765(00)80266-X","article-title":"GTP hydrolysis by Ran is required for nuclear envelope assembly","volume":"5","author":"Hetzer","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB28","doi-asserted-by":"crossref","first-page":"4685","DOI":"10.1242\/jcs.00136","article-title":"Chromosomal association of Ran during meiotic and mitotic divisions","volume":"115","author":"Hinkle","year":"2002","journal-title":"J. Cell Sci."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB29","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/0092-8674(92)90635-P","article-title":"Architecture and design of the nuclear pore complex","volume":"69","author":"Hinshaw","year":"1992","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB30","doi-asserted-by":"crossref","first-page":"4491","DOI":"10.1093\/emboj\/17.15.4491","article-title":"Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells","volume":"17","author":"J\u00e4kel","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB31","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1083\/jcb.200110109","article-title":"SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles","volume":"156","author":"Joseph","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB32","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0960-9822(99)80213-9","article-title":"The ran GTPase regulates mitotic spindle assembly","volume":"9","author":"Kalab","year":"1999","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB33","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1126\/science.1068798","article-title":"Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts","volume":"295","author":"Kalab","year":"2002","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB34","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0092-8674(84)90457-4","article-title":"A short amino acid sequence able to specify nuclear location","volume":"39","author":"Kalderon","year":"1984","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB35","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1083\/jcb.139.4.841","article-title":"Ran-unassisted nuclear migration of a 97-kD component of nuclear pore- targeting complex","volume":"139","author":"Kose","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB36","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1093\/emboj\/16.6.1153","article-title":"Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex","volume":"16","author":"Kutay","year":"1997","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB37","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0092-8674(84)90415-X","article-title":"Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen","volume":"37","author":"Lanford","year":"1984","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB38","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1006\/jmbi.2000.4055","article-title":"The adoption of a twisted structure of importin-beta is essential for the protein-protein interaction required for nuclear transport","volume":"302","author":"Lee","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB39","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S1534-5807(02)00134-X","article-title":"Protein and RNA export from the nucleus","volume":"2","author":"Lei","year":"2002","journal-title":"Dev. Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB40","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1083\/jcb.153.7.1391","article-title":"Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export","volume":"153","author":"Lindsay","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB41","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0092-8674(02)00836-X","article-title":"Npap60\/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import","volume":"110","author":"Lindsay","year":"2002","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB42","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1083\/jcb.200204163","article-title":"Influence of cargo size on Ran and energy requirements for nuclear protein import","volume":"159","author":"Lyman","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB43","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1128\/MMBR.65.4.570-594.2001","article-title":"Transport into and out of the nucleus","volume":"65","author":"Macara","year":"2001","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB44","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0092-8674(00)81862-0","article-title":"A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2","volume":"88","author":"Mahajan","year":"1997","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB45","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev.biochem.67.1.265","article-title":"Nucleocytoplasmic transport","volume":"67","author":"Mattaj","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB46","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1083\/jcb.135.6.1457","article-title":"A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex","volume":"135","author":"Matunis","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB47","doi-asserted-by":"crossref","first-page":"3685","DOI":"10.1093\/emboj\/20.14.3685","article-title":"Importin 13","volume":"20","author":"Mingot","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB48","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/1521-1878(200101)23:1<77::AID-BIES1010>3.0.CO;2-E","article-title":"The Ran-GTPase and cell-cycle control","volume":"23","author":"Moore","year":"2001","journal-title":"Bioessays"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB49","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1093\/embo-reports\/kve168","article-title":"Multiple pathways contribute to nuclear import of core histones","volume":"2","author":"Muhlhausser","year":"2001","journal-title":"EMBO Rep."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB50","doi-asserted-by":"crossref","first-page":"9622","DOI":"10.1073\/pnas.96.17.9622","article-title":"The direction of transport through the nuclear pore can be inverted","volume":"96","author":"Nachury","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB51","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0092-8674(01)00194-5","article-title":"Importin beta is a mitotic target of the small GTPase Ran in spindle assembly","volume":"104","author":"Nachury","year":"2001","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB52","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0960-9822(98)70039-9","article-title":"Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis","volume":"8","author":"Nakielny","year":"1997","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB53","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1126\/science.292.5521.1540","article-title":"Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B","volume":"292","author":"Nemergut","year":"2001","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB54","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1126\/science.284.5418.1356","article-title":"Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran","volume":"284","author":"Ohba","year":"1999","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB55","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0092-8674(00)80829-6","article-title":"PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation","volume":"101","author":"Ohno","year":"2000","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB56","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1091\/mbc.01-06-0308","article-title":"Nuclear pore complex is able to transport macromolecules with diameters of about 39 nm","volume":"13","author":"Pante","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB57","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/S0092-8674(02)00627-X","article-title":"A conserved mRNA export machinery coupled to pre-mRNA splicing","volume":"108","author":"Reed","year":"2002","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB58","doi-asserted-by":"crossref","first-page":"E201","DOI":"10.1038\/ncb0901-e201","article-title":"A new view of mRNA export","volume":"3","author":"Reed","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB59","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1093\/emboj\/20.6.1320","article-title":"Kinetic analysis of translocation through nuclear pore complexes","volume":"20","author":"Ribbeck","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB60","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1093\/emboj\/21.11.2664","article-title":"The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion","volume":"21","author":"Ribbeck","year":"2002","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB61","doi-asserted-by":"crossref","first-page":"6587","DOI":"10.1093\/emboj\/17.22.6587","article-title":"NTF2 mediates nuclear import of Ran","volume":"17","author":"Ribbeck","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB62","doi-asserted-by":"crossref","first-page":"16593","DOI":"10.1074\/jbc.R100015200","article-title":"The nuclear pore complex as a transport machine","volume":"276","author":"Rout","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB63","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1083\/jcb.148.4.635","article-title":"The yeast nuclear pore complex","volume":"148","author":"Rout","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB64","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1242\/jcs.113.7.1111","article-title":"The ran decathlon","volume":"113","author":"Sazer","year":"2000","journal-title":"J. Cell Sci."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB65","doi-asserted-by":"crossref","first-page":"4332","DOI":"10.1093\/emboj\/18.15.4332","article-title":"Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN\/Nup159p","volume":"18","author":"Schmitt","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB66","doi-asserted-by":"crossref","first-page":"35170","DOI":"10.1074\/jbc.273.52.35170","article-title":"Ran-dependent signal-mediated nuclear import does not require GTP hydrolysis by Ran","volume":"273","author":"Schwoebel","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB67","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1093\/emboj\/17.8.2196","article-title":"Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p","volume":"17","author":"Senger","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB68","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0960-9822(98)00023-2","article-title":"Nuclear import of Ran is mediated by the transport factor NTF2","volume":"8","author":"Smith","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB69","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1126\/science.1064732","article-title":"Systems analysis of Ran transport","volume":"295","author":"Smith","year":"2002","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB70","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1093\/emboj\/17.9.2663","article-title":"Dbp5p\/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export","volume":"17","author":"Snay-Hodge","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB71","doi-asserted-by":"crossref","unstructured":"Str\u00f6m, A.C., and Weis, K. (2001). Importin-beta-like nuclear transport receptors. Genome Biol 2, reviews3008.1\u20133008.9.","DOI":"10.1186\/gb-2001-2-6-reviews3008"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB72","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1093\/emboj\/17.9.2651","article-title":"Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export","volume":"17","author":"Tseng","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB73","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0955-0674(00)00221-0","article-title":"Nuclear pores and nuclear assembly","volume":"13","author":"Vasu","year":"2001","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB74","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0092-8674(00)80774-6","article-title":"Structural view of the Ran-Importin beta interaction at 2.3 \u00c5 resolution","volume":"97","author":"Vetter","year":"1999","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB75","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1083\/jcb.200202088","article-title":"The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import","volume":"158","author":"Walther","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB76","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/S0955-0674(02)00337-X","article-title":"Nucleocytoplasmic transport","volume":"14","author":"Weis","year":"2002","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB77","doi-asserted-by":"crossref","first-page":"7120","DOI":"10.1002\/j.1460-2075.1996.tb01103.x","article-title":"Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities","volume":"15","author":"Weis","year":"1996","journal-title":"EMBO J."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB78","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/0092-8674(95)90435-2","article-title":"Identification of a signal for rapid export of proteins from the nucleus","volume":"82","author":"Wen","year":"1995","journal-title":"Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB79","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1126\/science.1057661","article-title":"Role of importin-beta in coupling Ran to downstream targets in microtubule assembly","volume":"291","author":"Wiese","year":"2001","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB80","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1126\/science.284.5418.1359","article-title":"Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran","volume":"284","author":"Wilde","year":"1999","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB81","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/35060000","article-title":"Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities","volume":"3","author":"Wilde","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB82","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S1097-2765(00)80023-4","article-title":"Three-dimensional architecture of the isolated yeast nuclear pore complex","volume":"1","author":"Yang","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB83","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1083\/jcb.152.4.729","article-title":"The karyopherin Kap142p\/Msn5p mediates nuclear import and nuclear export of different cargo proteins","volume":"152","author":"Yoshida","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB84","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1126\/science.288.5470.1429","article-title":"Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts","volume":"288","author":"Zhang","year":"2000","journal-title":"Science"},{"key":"10.1016\/S0092-8674(03)00082-5_BIB85","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0960-9822(01)00053-7","article-title":"Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system","volume":"11","author":"Zhang","year":"2001","journal-title":"Curr. Biol."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB86","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1242\/jcs.112.14.2453","article-title":"Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts","volume":"112","author":"Zhang","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1016\/S0092-8674(03)00082-5_BIB87","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0960-9822(02)00714-5","article-title":"Role of importin-beta in the control of nuclear envelope assembly by Ran","volume":"12","author":"Zhang","year":"2002","journal-title":"Curr. Biol."}],"container-title":["Cell"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867403000825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0092867403000825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T10:47:48Z","timestamp":1758797268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0092867403000825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,2]]},"references-count":87,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,2]]}},"alternative-id":["S0092867403000825"],"URL":"https:\/\/doi.org\/10.1016\/s0092-8674(03)00082-5","relation":{},"ISSN":["0092-8674"],"issn-type":[{"value":"0092-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2003,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regulating Access to the Genome","name":"articletitle","label":"Article Title"},{"value":"Cell","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/S0092-8674(03)00082-5","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 Cell Press. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}