{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:40:31Z","timestamp":1775302831175,"version":"3.50.1"},"reference-count":93,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers & Chemistry"],"published-print":{"date-parts":[[2000,1]]},"DOI":"10.1016\/s0097-8485(00)80008-x","type":"journal-article","created":{"date-parts":[[2012,3,22]],"date-time":"2012-03-22T11:37:58Z","timestamp":1332416278000},"page":"71-94","source":"Crossref","is-referenced-by-count":54,"title":["A global compositional complexity measure for biological sequences: AT-rich and GC-rich genomes encode less complex proteins"],"prefix":"10.1016","volume":"24","author":[{"given":"Honghui","family":"Wan","sequence":"first","affiliation":[]},{"given":"John C.","family":"Wootton","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0097-8485(00)80008-X_BIB1","first-page":"8","article-title":"Compression of strings with approximate repeats","author":"Allison","year":"1998"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/ng0294-119","article-title":"Issues in searching molecular sequence databases","volume":"6","author":"Altschul","year":"1994","journal-title":"Nat. Genet."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0014-5793(75)80953-7","article-title":"A synthetic polypeptide with a compact structure and its self-organization","volume":"55","author":"Anufrieva","year":"1975","journal-title":"FEBS Lett."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB4","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/182111a0","article-title":"A correlation between the compositions of deoxyribonucleic and ribonucleic acids","volume":"182","author":"Belozersky","year":"1958","journal-title":"Nature"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB5","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1126\/science.4001930","article-title":"The mosaic genome of warm-blooded vertebrates","volume":"228","author":"Bernardi","year":"1985","journal-title":"Science"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB6","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/ng0498-313","article-title":"Predicting functions from protein sequences \u2014 where are the bottlenecks?","volume":"18","author":"Bork","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB7","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0022-5193(69)90041-1","article-title":"The information content of a multistate distribution","volume":"23","author":"Boulton","year":"1969","journal-title":"J. Theor. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB8","author":"Brillouin","year":"1962"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB9","doi-asserted-by":"crossref","first-page":"7524","DOI":"10.1073\/pnas.84.21.7524","article-title":"Spin glasses and the statistical mechanics of protein folding","volume":"84","author":"Bryngelson","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB10","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1145\/321356.321363","article-title":"On the length of programs for computing finite binary sequences","volume":"13","author":"Chaitin","year":"1966","journal-title":"J. Assoc. Comput. Mach."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB11","article-title":"Algorithmic Information Theory","volume":"vol. 1","author":"Chaitin","year":"1987"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB12","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1073\/pnas.58.5.1895","article-title":"Altered base ratios in the DNA of an Escherichia coli mutator strain","volume":"58","author":"Cox","year":"1967","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB13","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1128\/JB.100.1.390-397.1969","article-title":"Mutator gene studies in Escherichia coli","volume":"100","author":"Cox","year":"1969","journal-title":"J. Bacteriol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB14","first-page":"52","author":"Csiszar","year":"1981"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB15","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1103\/PhysRevB.24.2613","article-title":"Random-energy model: an exactly solvable model of disordered systems","volume":"24","author":"Derrida","year":"1981","journal-title":"Phys. Rev. B"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB16","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1007\/BF02102652","article-title":"Correlations between the compositional properties of human genes, codon usage, and amino acid composition of proteins","volume":"32","author":"D'Onofrio","year":"1991","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB17","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/32789","article-title":"Microbial genomes opened up","volume":"392","author":"Doolittle","year":"1998","journal-title":"Nature"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB18","first-page":"227","article-title":"On the concept of entropy of a finite probabilistic scheme","volume":"11","author":"Faddeev","year":"1956","journal-title":"Usp. Mat. Ces. Nauk. (New Series)"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB19","first-page":"48","article-title":"On the entropy of DNA: algorithms and measurements based on memory and rapid convergence","author":"Farach","year":"1995"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/PL00006155","article-title":"Converting amino acid alignment scores into measures of evolutionary time: a simulation study of various relationships","volume":"44","author":"Feng","year":"1997","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB21","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0959-440X(94)90112-0","article-title":"Implications of the random characteristics of protein sequences for their three-dimensional structure","volume":"4","author":"Finkelstein","year":"1994","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB22","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0022-5193(62)80005-8","article-title":"On the evolution of base composition of DNA","volume":"3","author":"Freese","year":"1962","journal-title":"J. Theor. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB23","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1007\/BF01840889","article-title":"Estimation of average number of substitutions when the rate of substitution varies with nucleotide","volume":"18","author":"Gojobori","year":"1982","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB24","doi-asserted-by":"crossref","first-page":"5899","DOI":"10.1073\/pnas.95.11.5899","article-title":"Estimation of evolutionary distances under stationary and non-stationary models of nucleotide substitution","volume":"95","author":"Gu","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB25","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0303-2647(93)90070-S","article-title":"The Lempel\u2014Ziv complexity and local structure analysis of genomes","volume":"30","author":"Gusev","year":"1993","journal-title":"Biosystems"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB26","author":"Hardy","year":"1952"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB27","author":"Hardy","year":"1938"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB28","doi-asserted-by":"crossref","first-page":"5849","DOI":"10.1073\/pnas.95.11.5849","article-title":"Measuring genome evolution","volume":"95","author":"Huynen","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.4064\/cm-9-1-131-150","article-title":"Information without probability","volume":"9","author":"Ingarden","year":"1962","journal-title":"Colloq. Math."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB30","first-page":"13","article-title":"Codon usage and tRNA content in unicellular and multicellular organisms","volume":"2","author":"Ikemura","year":"1985","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB31","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/BF02099949","article-title":"Silent nucleotide substitutions and G + C content of some mitochondrial and bacterial genes","volume":"24","author":"Jukes","year":"1986","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB32","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1073\/pnas.87.6.2264","article-title":"Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes","volume":"87","author":"Karlin","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB33","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1126\/science.8430316","article-title":"Patchiness and correlations in DNA sequences","volume":"259","author":"Karlin","year":"1993","journal-title":"Science"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB34","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1073\/pnas.78.1.454","article-title":"Estimation of evolutionary distances between homologous nucleotide sequences","volume":"78","author":"Kimura","year":"1981","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB35","series-title":"Sequences and codes: fundamentals of biomolecular cryptology","first-page":"119","author":"Konopka","year":"1994"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB36","series-title":"Non-continuous patterns and compositional complexity of nucleic acid sequences","first-page":"147","author":"Konopka","year":"1990"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB37","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0735-0651(90)90010-D","article-title":"Complexity charts can be used to map functional domain in DNA","volume":"7","author":"Konopka","year":"1990","journal-title":"Genet. Anal.: Tech. Appl."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB38","first-page":"1","article-title":"Three approaches to the quantitative definition of information","volume":"1","author":"Kolmogorov","year":"1965","journal-title":"Probl. Inf. Transm."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB39","author":"Kullback","year":"1959"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB40","first-page":"212","article-title":"Contenu en bases puriques et pyrimidiques des acids desoxyribonucleiques des bacteries","volume":"91","author":"Lee","year":"1956","journal-title":"Ann. l'Institut Pasteur"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB41","author":"Li","year":"1993"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB42","author":"Lichtenberg","year":"1992"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB43","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1089\/cmb.1999.6.125","article-title":"Significantly lower entropy estimates for natural DNA sequences","volume":"6","author":"Loewenstern","year":"1999","journal-title":"J. Comput. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB44","first-page":"36","article-title":"Information theory in ecology","volume":"3","author":"Margalef","year":"1958","journal-title":"Gen. Sys."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB45","first-page":"407","article-title":"Discovering simple DNA sequences by the algorithmic significance method","volume":"9","author":"Milosavljevic","year":"1993","journal-title":"Comput. Appl. Biosci."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB46","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1073\/pnas.84.1.166","article-title":"The guanine and cytosine content of genomic DNA and bacterial evolution","volume":"84","author":"Muto","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB47","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1002\/pro.5560040820","article-title":"Gibbs motif sampling: detection of bacterial outer membrane protein repeats","volume":"4","author":"Neuwald","year":"1995","journal-title":"Protein Sci."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB48","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0959-440X(98)80013-4","article-title":"Simplified proteins: minimalist solutions to the \u2018protein folding problem\u2019","volume":"8","author":"Plaxco","year":"1998","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB49","series-title":"Protein as an \u2018edited\u2019 statistical copolymer?","first-page":"49","author":"Ptitsyn","year":"1983"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB50","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0065-3233(08)60546-X","article-title":"Molten globule and protein folding","volume":"47","author":"Ptitsyn","year":"1995","journal-title":"Adv. Protein Chem."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0969-2126(98)00001-X","article-title":"Proteins to order?","volume":"6","author":"Regan","year":"1997","journal-title":"Structure"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB52","first-page":"547","article-title":"On measures of entropy and information","author":"Renyi","year":"1961"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/1401301","article-title":"On the foundations of information theory","volume":"33","author":"Renyi","year":"1965","journal-title":"Rev. l'Institut Int. Stat."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB54","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/nsb1097-805","article-title":"Functional rapidly folding proteins from simplified amino acid sequences","volume":"4","author":"Riddle","year":"1997","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB55","first-page":"215","article-title":"Fast discerning repeats in DNA sequences with a compression algorithm","author":"Rivals","year":"1997"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB56","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1073\/pnas.45.7.1039","article-title":"The relative homogeneity of microbial DNA","volume":"45","author":"Rolfe","year":"1959","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB57","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1007\/BF02407350","article-title":"Time and Biosequences","volume":"37","author":"Saccone","year":"1993","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB58","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0097-8485(92)80038-2","article-title":"A maximum entropy principle for distribution of local complexity in naturally occurring nucleotide sequences","volume":"16","author":"Salamon","year":"1992","journal-title":"Comput. Chem."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB59","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0097-8485(93)85005-W","article-title":"On the robustness of maximum entropy relationships for complexity distributions of nucleotide sequences","volume":"17","author":"Salamon","year":"1993","journal-title":"Comput. Chem."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB60","first-page":"623","article-title":"A note on the concept of entropy","volume":"9","author":"Segal","year":"1960","journal-title":"J. Math. Mech."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB61","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0301-4622(89)80058-4","article-title":"Formation of unique structure in polypeptide chains: Theoretical investigation with the aid of a replica approach","volume":"34","author":"Shakhnovich","year":"1989","journal-title":"Biophys. Chem."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB62_1","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/j.1538-7305.1948.tb01338.x","article-title":"A mathematical theory of communication","volume":"27","author":"Shannon","year":"1948","journal-title":"Bell Syst. Tech. J."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB62_2","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/j.1538-7305.1948.tb00917.x","article-title":"A mathematical theory of communication","volume":"27","author":"Shannon","year":"1948","journal-title":"Bell Syst. Tech. J."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB63","article-title":"The Ergodic Theory of Discrete Sample Paths","volume":"vol. 13","author":"Shields","year":"1996"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0019-9958(64)90223-2","article-title":"A formal theory of inductive inference. I","volume":"7","author":"Solomonoff","year":"1964","journal-title":"Inf. Control"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB65","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0019-9958(64)90131-7","article-title":"A formal theory of inductive inference. II","volume":"7","author":"Solomonoff","year":"1964","journal-title":"Inf. Control"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB66","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/nar\/12.1Part2.521","article-title":"Graphic methods to determine the function of nucleic acid sequences","volume":"12","author":"Staden","year":"1984","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB67","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1073\/pnas.45.10.1480","article-title":"A statistical analysis of deoxyribonucleic acid distribution in density gradient centrifugation","volume":"45","author":"Sueoka","year":"1959","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB68","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1101\/SQB.1961.026.01.009","article-title":"Compositional correlation between deoxyribonucleic acid and protein","volume":"26","author":"Sueoka","year":"1961","journal-title":"Cold Spring Harbor Symp. Quant. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB69","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1073\/pnas.48.4.582","article-title":"On the genetic basis of variation and heterogeneity of DNA base composition","volume":"48","author":"Sueoka","year":"1962","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB70","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1073\/pnas.85.8.2653","article-title":"Directional mutation pressure and neutral molecular evolution","volume":"85","author":"Sueoka","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB71","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/BF00182387","article-title":"Directional mutation pressure, selective constraints, and genetic equilibria","volume":"34","author":"Sueoka","year":"1992","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB72","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF02407349","article-title":"Directional mutation pressure, mutator mutations, and dynamics of molecular evolution","volume":"37","author":"Sueoka","year":"1993","journal-title":"J. Mol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB73","first-page":"677","article-title":"Unbiased estimation of evolutionary distance between nucleotide sequences","volume":"10","author":"Tajima","year":"1993","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB74","first-page":"678","article-title":"Estimation of the number of nucleotide substitutions when there are strong transition-transversion and G + C content biases","volume":"9","author":"Tamura","year":"1992","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB75","first-page":"1148","article-title":"Freeing phylogenies from artifacts of alignment","volume":"9","author":"Thorne","year":"1992","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB76","article-title":"Making sense of the human genome","volume":"vol. 1","author":"Trifonov","year":"1990"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB77","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/comjnl\/11.2.185","article-title":"An information measure for classification","volume":"11","author":"Wallace","year":"1968","journal-title":"Comput. J."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB78","first-page":"87","article-title":"Structure and cardinality of the class A(R, S) of (0, 1)-matrices","volume":"4","author":"Wan","year":"1984","journal-title":"J. Math. Res. Expo."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB79","article-title":"(0, 1)-matrices class with prescribed row and column sums associated with integral partition lattices","author":"Wan","year":"1984"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB80","first-page":"117","article-title":"Cardinal function of the class A(R, S) of (0, 1)-matrices and its nonzero-point set in integra partition lattices","volume":"5","author":"Wan","year":"1985","journal-title":"J. Math. Res. Expo."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB81","author":"Wan","year":"1986"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB82","first-page":"289","article-title":"On the structure and enumeration of (0, 1)-matrices in integral partition lattices","volume":"30","author":"Wan","year":"1987","journal-title":"Acta Math. Sin."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB83","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0012-365X(94)00066-R","article-title":"On nearly self-conjugate partition of a finite set","volume":"175","author":"Wan","year":"1997","journal-title":"Discret. Math."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB84","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0012-365X(86)90092-0","article-title":"On the number of tournaments with prescribed score vector","volume":"61","author":"Wan","year":"1986","journal-title":"Discret. Math."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB85","article-title":"Compositional complexity functions of biological sequences in integral partition lattices","author":"Wan","year":"1998","journal-title":"Adv. Appl. Math."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB86","first-page":"77","article-title":"Axiomatic foundations of complexity functions of biological sequences","volume":"3","author":"Wan","year":"1998","journal-title":"Ann. Comb."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB87","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/nsb1197-871","article-title":"As simple as can be?","volume":"4","author":"Wolynes","year":"1997","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB88","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0097-8485(94)85023-2","article-title":"Non-globular domains in protein sequences: automated segmentation using complexity measures","volume":"18","author":"Wootton","year":"1994","journal-title":"Comput. Chem."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB89","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0959-440X(94)90111-2","article-title":"Sequences with \u2018unusual\u2019 amino acid compositions","volume":"4","author":"Wootton","year":"1994","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB90","series-title":"Simple sequences of protein and DNA","first-page":"169","author":"Wootton","year":"1997"},{"key":"10.1016\/S0097-8485(00)80008-X_BIB91","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0097-8485(93)85006-X","article-title":"Statistics of local complexity in amino acid sequences and sequence databases","volume":"17","author":"Wootton","year":"1993","journal-title":"Comput. Chem."},{"key":"10.1016\/S0097-8485(00)80008-X_BIB92","series-title":"Analysis of compositionally biased regions in sequence databases","first-page":"554","volume":"vol. 266","author":"Wootton","year":"1996"}],"container-title":["Computers & Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009784850080008X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009784850080008X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,4]],"date-time":"2020-07-04T15:10:24Z","timestamp":1593875424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009784850080008X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":93,"aliases":["10.1016\/s0097-8485(99)00048-0"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["S009784850080008X"],"URL":"https:\/\/doi.org\/10.1016\/s0097-8485(00)80008-x","relation":{},"ISSN":["0097-8485"],"issn-type":[{"value":"0097-8485","type":"print"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}