{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T11:43:18Z","timestamp":1774784598786,"version":"3.50.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1997,1,1]],"date-time":"1997-01-01T00:00:00Z","timestamp":852076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computers & Chemistry"],"published-print":{"date-parts":[[1997,1]]},"DOI":"10.1016\/s0097-8485(96)00040-x","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T02:58:12Z","timestamp":1027652292000},"page":"223-227","source":"Crossref","is-referenced-by-count":53,"title":["Detection of eukaryotic promoters using Markov transition matrices"],"prefix":"10.1016","volume":"21","author":[{"given":"St\u00e9phane","family":"Audic","sequence":"first","affiliation":[]},{"given":"Jean-Michel","family":"Claverie","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0097-8485(96)00040-X_BIB1","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1093\/nar\/18.7.1847","article-title":"Application of a new method of pattern recognition in DNA sequence analysis: a study of E. coli promoters","volume":"18","author":"Alexandrov","year":"1990","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB2","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0022-2836(90)90223-9","article-title":"Weight matrix description of four eukaryotic RNA Polymerase II promoter elements derived from 502 unrelated promoter sequences","volume":"212","author":"Bucher","year":"1990","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB3","article-title":"The Eukaryotic Promoter Database EPD","author":"Bucher","year":"1996"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB4","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0097-8485(93)85004-V","article-title":"GENMARK: parallel gene recognition for both DNA strands","volume":"17","author":"Borodovsky","year":"1993","journal-title":"Computers and Chemistry"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB5","first-page":"431","article-title":"The statistical significance of nucleotide position-weight matrix matches","volume":"12","author":"Claverie","year":"1996","journal-title":"Computers Applications in the Biosciences"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB6","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0097-8485(96)00039-3","article-title":"The difficulty of identifying genes in anonymous vertebrate sequence","volume":"21","author":"Claverie","year":"1997","journal-title":"Computers and Chemistry"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB7","first-page":"95","article-title":"Assessing the biological significance of primary structure consensus patterns using sequence databanks. I. Heat-shock and glucocorticoid control elements in eukaryotic promoters","volume":"1","author":"Claverie","year":"1985","journal-title":"Computer Applications in the Biosciences"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB8","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0076-6879(90)83017-4","article-title":"k-tuple frequency analysis: from intron\/exon discrimination to T-cell epitope mapping","volume":"183","author":"Claverie","year":"1990","journal-title":"Methods in Enzymology"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB9","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1093\/nar\/19.7.1593","article-title":"Neural network optimization for E. coli promoter prediction","volume":"19","author":"Demeler","year":"1991","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB10","doi-asserted-by":"crossref","first-page":"6441","DOI":"10.1093\/nar\/20.24.6441","article-title":"Assessment of protein coding measures","volume":"20","author":"Fickett","year":"1992","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB11","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0076-6879(96)73004-5","article-title":"E. coli promoter sequence: analysis and prediction","volume":"273","author":"Hertz","year":"1996","journal-title":"Methods in Enzymology"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB12","doi-asserted-by":"crossref","first-page":"7211","DOI":"10.1021\/bi00147a001","article-title":"Prediction of structural and functional features of protein and nucleic acids sequences by artificial neural networks","volume":"31","author":"Hirst","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB13","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1093\/nar\/20.16.4331","article-title":"An assessment of neural network and statistical approaches for prediction of E. coli promoter sites","volume":"20","author":"Horton","year":"1992","journal-title":"Nucleic Acids Research"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB14","first-page":"391","article-title":"The prediction of vertebrate promoter regions using differential hexamer frequency analysis","volume":"12","author":"Hutchinson","year":"1996","journal-title":"Computer Applications in the Biosciences"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0097-8485(96)80015-5","article-title":"Detection of RNA Polymerase II promoters and polyadenylation sites in human DNA sequences","volume":"20","author":"Matis","year":"1996","journal-title":"Computers and Chemistry"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB16","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1006\/jmbi.1995.0349","article-title":"Predicting Pol II promoter sequence using transcription factor binding sites","volume":"249","author":"Prestridge","year":"1995","journal-title":"Journal of Molecular Biology"},{"key":"10.1016\/S0097-8485(96)00040-X_BIB17","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0168-1656(94)90041-8","article-title":"Recognition of regulatory regions in genomic sequences","volume":"35","author":"Wingender","year":"1994","journal-title":"Journal of Biotechnology"}],"container-title":["Computers & Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009784859600040X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009784859600040X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,14]],"date-time":"2019-04-14T01:59:42Z","timestamp":1555207182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009784859600040X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1997,1]]}},"alternative-id":["S009784859600040X"],"URL":"https:\/\/doi.org\/10.1016\/s0097-8485(96)00040-x","relation":{},"ISSN":["0097-8485"],"issn-type":[{"value":"0097-8485","type":"print"}],"subject":[],"published":{"date-parts":[[1997,1]]}}}