{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T10:37:21Z","timestamp":1766486241802},"reference-count":21,"publisher":"Elsevier BV","issue":"8900","license":[{"start":{"date-parts":[[1994,3,1]],"date-time":"1994-03-01T00:00:00Z","timestamp":762480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Lancet"],"published-print":{"date-parts":[[1994,3]]},"DOI":"10.1016\/s0140-6736(94)91835-x","type":"journal-article","created":{"date-parts":[[2003,9,22]],"date-time":"2003-09-22T21:50:55Z","timestamp":1064267455000},"page":"749-753","source":"Crossref","is-referenced-by-count":223,"title":["Impact of long-term acyclovir on cytomegalovirus infection and survival after allogeneic bone marrow transplantation"],"prefix":"10.1016","volume":"343","author":[{"given":"H.G.","family":"Prentice","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Gluckman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Powles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Ljungman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.J.","family":"Milpied","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Fernandez-Ra\u00f1ada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Mandelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Kho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.R.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/S0140-6736(94)91835-X_BIB1","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1182\/blood.V62.5.941.941","article-title":"Allogeneic bone marrow transplantation: current status and future directions","volume":"62","author":"O'Reilly","year":"1983","journal-title":"Blood"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB2","first-page":"101","article-title":"Cytomegalovirus infection following marrow transplantation: risk, treatment and prevention","volume":"20","author":"Meyers","year":"1984","journal-title":"Birth Defects: Original Article Series"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB3","doi-asserted-by":"crossref","first-page":"783","DOI":"10.7326\/0003-4819-109-10-783","article-title":"Treatment of cytomegalovirus pneumonia with ganciclovir and intravenous cytomegalovirus immunoglobulin in patient with bone marrow transplants","volume":"109","author":"Reed","year":"1988","journal-title":"Ann Intern Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB4","doi-asserted-by":"crossref","first-page":"777","DOI":"10.7326\/0003-4819-109-10-777","article-title":"Cytomegalovirus pneumonia after bone marrow transplantation successfully treated with the combination of ganciclovir and high dose intravenous immune globulin","volume":"109","author":"Emmanuel","year":"1988","journal-title":"Ann Intern Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB5","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1097\/00007890-198812000-00022","article-title":"Ganciclovir\/immunoglobulin combination therapy for the treatment of human cytomegalovirus-associated interstitial pneumonia in bone marrow allograft recipients","volume":"46","author":"Schmidt","year":"1988","journal-title":"Transplantation"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB6","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/clinids\/14.4.831","article-title":"Cytomegalovirus interstitial pneumonitis: treatment with ganciclovir and intravenous immune globulin. European Bone Marrow Transplant Group Experience","volume":"14","author":"Ljungman","year":"1992","journal-title":"Clin Infect Dis"},{"issue":"suppl B","key":"10.1016\/S0140-6736(94)91835-X_BIB7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/jac\/12.suppl_B.153","article-title":"Use of acyclovir for prophylaxis of herpes infections in severely immunocompromised patients","volume":"12","author":"Prentice","year":"1983","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB8","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1056\/NEJM198107093050202","article-title":"Acyclovir prophylaxis of herpes simplex virus infections","volume":"305","author":"Saral","year":"1981","journal-title":"N Engl J Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB9","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/bjc.1989.88","article-title":"The prophylactic role of intravenous and long-term oral acyclovir after allogeneic bone marrow transplant","volume":"59","author":"Selby","year":"1989","journal-title":"Br J Cancer"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB10","first-page":"185","article-title":"Long term acyclovir prophylaxis in bone marrow transplant recipients and lymphocyte proliferation responses to herpes virus antigen in vitro","volume":"1","author":"Ljungman","year":"1986","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB11","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1093\/jac\/8.1.65","article-title":"The in vitro activity of acyclovir and related compounds against cytomegalovirus infections","volume":"8","author":"Tyms","year":"1981","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB12","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1056\/NEJM198801143180202","article-title":"Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation","volume":"318","author":"Meyers","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB13","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1056\/NEJM198905253202105","article-title":"A randomised, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allografts","volume":"320","author":"Balfour","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB14","first-page":"319","article-title":"Cytomegalovirus infection depresses monocyte production of interleukin- 1","author":"Smith","year":"1985"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB15","first-page":"560A","article-title":"Cytomegalovirus directly depresses the functions of natural killer cells","volume":"33","author":"Rook","year":"1985","journal-title":"Clin Res"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB16","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00007890-198504000-00008","article-title":"Faster immunological recovery after bone marrow transplantation in patients without cytomegalovirus infection","volume":"39","author":"Paulin","year":"1985","journal-title":"Transplantation"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB17","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/jmv.1890230412","article-title":"Incidence and prognosis of cytomegalovirus infections following allogeneic bone marrow transplantation","volume":"23","author":"Guyotat","year":"1987","journal-title":"J Med Virol"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB18","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7326\/0003-4819-118-3-199302010-00004","article-title":"Ganciclovir prophylaxis of cytomegalovirus infection and disease in allogeneic bone marrow transplant recipients: results of a placebo-controlled, double-blind trial","volume":"118","author":"Winston","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB19","doi-asserted-by":"crossref","first-page":"173","DOI":"10.7326\/0003-4819-118-3-199302010-00003","article-title":"Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant","volume":"118","author":"Goodrich","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB20","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/0002-9343(88)90313-0","article-title":"Acyclovir induced renal failure: clinical course and histology","volume":"84","author":"Sawyer","year":"1993","journal-title":"Am J Med"},{"key":"10.1016\/S0140-6736(94)91835-X_BIB21","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1056\/NEJM198601233140404","article-title":"Treatment of varicella zoster virus infection in severely immunocompromised patients: a randomisd comparison of acyclovir and vidarabine","volume":"314","author":"Shepp","year":"1986","journal-title":"N Engl J Med"}],"container-title":["The Lancet"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014067369491835X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014067369491835X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T18:20:30Z","timestamp":1585160430000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014067369491835X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,3]]},"references-count":21,"journal-issue":{"issue":"8900","published-print":{"date-parts":[[1994,3]]}},"alternative-id":["S014067369491835X"],"URL":"https:\/\/doi.org\/10.1016\/s0140-6736(94)91835-x","relation":{},"ISSN":["0140-6736"],"issn-type":[{"value":"0140-6736","type":"print"}],"subject":[],"published":{"date-parts":[[1994,3]]}}}