{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T02:30:26Z","timestamp":1768271426741,"version":"3.49.0"},"reference-count":168,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1996,12,1]],"date-time":"1996-12-01T00:00:00Z","timestamp":849398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychiatry Research"],"published-print":{"date-parts":[[1996,12]]},"DOI":"10.1016\/s0165-1781(96)02923-x","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T23:41:21Z","timestamp":1027640481000},"page":"143-157","source":"Crossref","is-referenced-by-count":65,"title":["Faulty cortisol\/serotonin interplay. Psychopathological and biological characterisation of a new, hypothetical depression subtype (SeCA depression)"],"prefix":"10.1016","volume":"65","author":[{"given":"Herman M.","family":"van Praag","sequence":"first","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0165-1781(96)02923-X_BIB1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1600-0447.1991.tb05574.x","article-title":"Low brain uptake of l-[11C]5-hydroxytryptophan in major depression; a positron emission tomography study on patients and healthy volunteers","volume":"83","author":"\u00c5gren","year":"1991","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/1098-2337(1994)20:3<235::AID-AB2480200310>3.0.CO;2-J","article-title":"Effects of neonatal treatment with 1-(2,5-di-methoxy-4-iodophenyl)-2 aminopropane HCI (DOI) and ritanserin on agonistic behavior in adult male and female rats","volume":"20","author":"Albonetti","year":"1994","journal-title":"Aggress Behav"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB3","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1176\/ajp.151.11.1626","article-title":"Neuroendocrine and behavioral responses to intravenous m-chlorophenyl-piperazine (mCPP) in depressed patients and healthy comparison subjects","volume":"151","author":"Anand","year":"1994","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB4","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/ddr.430260307","article-title":"Electrophysiology of 5-HT1A receptors in rat hippocampus and cortex","volume":"26","author":"Andrade","year":"1992","journal-title":"Drug Dev Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB5","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/0014-2999(94)00473-0","article-title":"5-HT1a receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours, respectively","volume":"264","author":"Andrews","year":"1994","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB6","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1002\/hup.470080407","article-title":"Pilot study of flesinoxan, a 5-HT1a agonist, in major depression: effects on sleep REM latency and body temperature","volume":"8","author":"Ansseau","year":"1993","journal-title":"Hum Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB7","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0165-1781(90)90086-K","article-title":"Interrelationships among anxiety, aggression, impulsivity, and mood: a serotoninergically linked cluster","volume":"32","author":"Apter","year":"1990","journal-title":"Psychiatry Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB8","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1176\/ajp.152.2.265","article-title":"Dexamethasone for the treatment of depression: a randomized, placebo-controlled, double-blind trial","volume":"152","author":"Arana","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB9","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0306-4522(91)90128-B","article-title":"5-Hydroxytryptamine 2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in rat association cortex","volume":"40","author":"Araneda","year":"1991","journal-title":"Neuroscience"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00004714-199204001-00002","article-title":"Alterations in monoamine receptors in the brain of suicide victims","volume":"12","author":"Arango","year":"1992","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB11","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0024-3205(89)90384-6","article-title":"Increased serotonin2 (5-HT2) receptor binding as measured by [3H]lysergic acid diethylamide (3H-LSD) in the blood platelets of depressed patients","volume":"44","author":"Arora","year":"1989","journal-title":"Life Sci"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB12","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/0006-3223(94)90044-2","article-title":"Brain 5-HT1A, 5-HT1D and 5-HT2 receptors in suicide victims","volume":"35","author":"Arranz","year":"1994","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB13","series-title":"Psychopharmacology: The Third Generation of Progress","first-page":"655","article-title":"Psychobiology of suicide, impulsivity, and related phenomena","author":"\u00c5sberg","year":"1987"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB14","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1126\/science.1246632","article-title":"\u2018Serotonin depression\u2019 \u2014 a biochemical subgroup within the affective disorders?","volume":"191","author":"\u00c5sberg","year":"1976","journal-title":"Science"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB15","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1126\/science.6143403","article-title":"Stress hormones: their interaction and regulation","volume":"224","author":"Axelrod","year":"1984","journal-title":"Science"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB16","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0014-2999(92)90417-3","article-title":"Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists","volume":"210","author":"Bagdy","year":"1992","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0165-0327(84)80012-9","article-title":"Biochemical markers in suicidal patients. Investigations with cerebrospinal fluid amine metabolites and neuroencodrine tests","volume":"6","author":"Banki","year":"1984","journal-title":"J Affect Disord"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB18","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/0166-2236(95)93942-Q","article-title":"Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system?","volume":"18","author":"Barden","year":"1995","journal-title":"Trends Neurosci"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB19","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0149-7634(94)90046-9","article-title":"5-HT1a receptor influences on rodent social and agonistic behavior: a review and empirical study","volume":"18","author":"Bell","year":"1994","journal-title":"Neurosci Behav Rev"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB20","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1001\/archpsyc.1994.03950090019003","article-title":"Mood lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major effective disorders","volume":"51","author":"Benkelfat","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB21","first-page":"5918","article-title":"Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene","volume":"91","author":"Berrettini","year":"1994"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB22","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF02245747","article-title":"Serotonin 5-HT2 receptor binding on blood platelets as a state dependent marker in major affective disorder","volume":"102","author":"Biegon","year":"1990","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB23","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/0165-6147(94)90315-8","article-title":"Current advances and trends in the treatment of depression","volume":"15","author":"Blier","year":"1994","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB24","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1007\/BF02245966","article-title":"Reduction in serotonin 5HT2 receptor binding on platelets of delinquent adolescents","volume":"118","author":"Blumensohn","year":"1995","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB25","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0091-3057(94)90427-8","article-title":"Serotonergic control of androgeninduced dominance","volume":"49","author":"Bonson","year":"1994","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB26","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1677\/joe.0.1360381","article-title":"Effect of selective serotonin agonists on basal corti-cotrophin-releasing hormone- and vasopressin-induced ACTH release in vitro from rat pituitary cells","volume":"136","author":"Calogero","year":"1993","journal-title":"J Endocrinol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB27","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1192\/bjp.140.3.292","article-title":"The dexamethasone suppression test for melancholia","volume":"140","author":"Carroll","year":"1982","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB28","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/BF00500007","article-title":"Effect of a selective 5-HT reuptake blocker citalopram on the sensitivity of 5-HT autoreceptors: electrophysiological studies in the rat brain","volume":"333","author":"Chaput","year":"1986","journal-title":"Naunyn Schmiedeberg's Arch Pharmacol"},{"issue":"Suppl. 15","key":"10.1016\/S0165-1781(96)02923-X_BIB29","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1192\/S0007125000296633","article-title":"Neuroendocrine mechanisms and the precipitation of depression by life events","volume":"160","author":"Checkley","year":"1992","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB30","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/0006-8993(88)91621-6","article-title":"Brain 5-HT2 binding sites in depressed suicide victims","volume":"443","author":"Cheetham","year":"1988","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB31","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/BF02247138","article-title":"Brain 5-HT1 binding sites in depressed suicides","volume":"102","author":"Cheetham","year":"1990","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB32","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0028-3908(91)90178-E","article-title":"Involvement of 5-HT1a receptors in the antidepressant-like activity of gepirone in the forced swimming test in rats","volume":"30","author":"Chojnacka-Wojcik","year":"1991","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB33","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/BF02245252","article-title":"The effect of tryptophan depletion and enhancement on subjective and behavioural aggression in normal male subjects","volume":"118","author":"Cleare","year":"1995","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB34","series-title":"Second International Conference on New Directions in Affective Disorders","article-title":"Prolactin and cortisol responses to d-fenfluramine in depression: relation to suicide and hypercortisolaemia","author":"Cleare","year":"1995"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB35","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00004850-199200710-00001","article-title":"Impulsive aggression and central serotonergic system function in humans; an example of a dimensional brain-behavior relationship","volume":"7","author":"Coccaro","year":"1992","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB36","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1192\/bjp.142.5.498","article-title":"Dexamethasone suppression test in depression and other psychiatric illness","volume":"142","author":"Coppen","year":"1983","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB37","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/S0140-6736(67)91894-6","article-title":"Tryptophan in the treatment of depression","volume":"II","author":"Coppen","year":"1967","journal-title":"Lancet"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB38","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/hup.470090509","article-title":"The effect of tryptophan on brain 5-HT function: a review","volume":"9","author":"Cowen","year":"1994","journal-title":"Hum Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB39","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1017\/S0033291700029834","article-title":"Biological markers of depression","volume":"21","author":"Cowen","year":"1991","journal-title":"Psychol Med"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB40","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/BF02245954","article-title":"Long-lasting effects of an acute stress on the neurochemistry and function of 5-hydroxytryptaminergic neurones in the mouse brain","volume":"118","author":"Davis","year":"1995","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB41","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1177\/026988119300700308","article-title":"A review of clinical efficacy of 5-HT1a agonists in anxiety and depression","volume":"7","author":"Deakin","year":"1993","journal-title":"J Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB42","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1177\/026988119100500414","article-title":"Critique, 5-HT and mechanisms of defence","volume":"5","author":"Deakin","year":"1991","journal-title":"J Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB43","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF02253723","article-title":"A neuroendocrine study of 5HT function in depression: evidence for biological mechanisms of endogenous and psychosocial causation","volume":"101","author":"Deakin","year":"1990","journal-title":"J Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB44","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0014-2999(94)00548-6","article-title":"Effects of intracerebroventricular administration of 5-HT receptor agonist on the maternal aggression of rats","volume":"264","author":"De Almeida","year":"1994","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB45","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1001\/archpsyc.1994.03950110025005","article-title":"Serotonin and the neurobiology of depression: effects of tryptophan depletion in drug-free depressed patients","volume":"51","author":"Delgado","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB46","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1086\/415144","article-title":"The integration of dominance and social bonding in primates","volume":"61","author":"De Waal","year":"1986","journal-title":"Q Rev Biol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB47","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0925-4927(92)90018-Y","article-title":"SPECT imaging of serotonin2 receptors in depression","volume":"45","author":"D'Haenen","year":"1992","journal-title":"Psychiatry Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB48","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1192\/bjp.164.3.365","article-title":"Glucocorticoids and the genesis of depressive illness. A psychobiological model","volume":"164","author":"Dinan","year":"1994","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB49","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1176\/ajp.148.7.823","article-title":"Prodromal symptoms in affective disorders","volume":"148","author":"Fava","year":"1991","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB50","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/0028-3908(94)90076-0","article-title":"Evidence that mCPP-induced anxiety in the plus-maze is mediated by postsynaptic 5-HT2c receptors but not by sympathomimetic effects","volume":"33","author":"Gibson","year":"1994","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB51","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1056\/NEJM198605223142101","article-title":"Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease","volume":"314","author":"Gold","year":"1986","journal-title":"New Engl J Med"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB52","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1001\/archpsyc.1983.01790050019002","article-title":"Dexamethasone suppression test in antidepressant treatment of melancholia","volume":"4","author":"Greden","year":"1983","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB53","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0091-3057(92)90440-Q","article-title":"Domestication alters 5-HT1a receptor binding in rat brain","volume":"42","author":"Hamer","year":"1992","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB54","series-title":"Psychopharmacology: The Third Generation of Progress","first-page":"535","article-title":"Mechanisms of action of antidepressant treatments: implications for the etiology and treatment of depressive illness","author":"Heninger","year":"1987"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB55","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1365-2826.1994.tb00591.x","article-title":"Prenatal stress increases the hypothalamo-pituitary-adrenal axis response in young and adult rats","volume":"6","author":"Henry","year":"1994","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB56","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1001\/archpsyc.1992.01820060016002","article-title":"Cerebrospinal fluid monoamine and adrenal correlates of aggression in free-ranging rhesus monkeys","volume":"49","author":"Higley","year":"1992","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB57","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/0006-3223(86)90121-6","article-title":"Human corticotropin-releasing hormone in depression \u2014 correlation with thyrotropin secretion following thyrotropin-releasing hormone","volume":"21","author":"Holsboer","year":"1986","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB58","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0165-1781(91)90041-M","article-title":"Repeated administration of the combined dexamethasone-human corticotropin releasing hormone stimulation test during treatment of depression","volume":"38","author":"Holsboer-Trachsler","year":"1991","journal-title":"Psychiatry Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB59","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0006-8993(93)91015-K","article-title":"5-HT uptake sites and 5-HT2 receptors in brain of antidepressant-free suicide victims\/depressives: increase in 5-HT2 sites in cortex and amygdala","volume":"614","author":"Hrdina","year":"1993","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB60","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0149-7634(05)80175-7","article-title":"Mechanisms of stress: a dynamic overview of hormonal and behavioral homeostasis","volume":"16","author":"Johnson","year":"1992","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB61","first-page":"920","article-title":"Are postsynaptic 5-HT1a receptors involved in the anxiolytic effects of 5-HT1a receptor agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat?","volume":"272","author":"Jolas","year":"1995","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB62","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/hup.470030409","article-title":"A serotonin hypothesis of panic disorder","volume":"3","author":"Kahn","year":"1988","journal-title":"Hum Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB63","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/0006-3223(90)90663-M","article-title":"Serotonin receptor sensitivity in major depression","volume":"28","author":"Kahn","year":"1990","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB64","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1017\/S0033291700022236","article-title":"Identifying the specific clinical actions of amitriptyline: interrelationships of behavior, affect, and plasma levels in depression","volume":"21","author":"Katz","year":"1991","journal-title":"Psychol Med"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB65","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1476-5381.1988.tb11508.x","article-title":"Evidence that mCPP may have behavioural effects mediated by central 5-HT1c receptors","volume":"94","author":"Kennett","year":"1988","journal-title":"Br J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB66","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0006-8993(85)90684-5","article-title":"Enhancement of some 5-HT-dependent behavioral responses following repeated immobilization in rats","volume":"330","author":"Kennett","year":"1985","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB67","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/BF02245448","article-title":"Evidence that 5-HT2c receptor antagonists are anxiolytic in the rat Geller-Seifter model of anxiety","volume":"114","author":"Kennett","year":"1994","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB68","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02245281","article-title":"Effect of ACTH, adrenalectomy and the combination treatment on the density of 5-HT2 receptor binding sites in neocortex of rat forebrain and 5-HT2 receptor-mediated wet-dog shake behaviors","volume":"108","author":"Kuroda","year":"1992","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB69","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0031-9384(94)00219-U","article-title":"Aggression and brain serotonergic responsivity: response to slides in male macaques","volume":"57","author":"Kyes","year":"1995","journal-title":"Physiol Behav"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB70","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/0006-3223(90)90400-V","article-title":"5-HT1a receptor responsivity in unipolar depression evaluation of ipsapirone-induced ACTH and Cortisol secretion in patients and controls","volume":"28","author":"Lesch","year":"1990","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB71","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1055\/s-2007-979587","article-title":"The concentration of neurotransmitter metabolites in the cerebrospinal fluid of suicidal individuals: a meta-analysis","volume":"28","author":"Lester","year":"1995","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB72","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1016\/0024-3205(83)90344-2","article-title":"Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior","volume":"33","author":"Linnoila","year":"1983","journal-title":"Life Sci"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB73","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/BF00489545","article-title":"Synaptic interaction of serotonergic releasing factor (CRF) synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. A light and electron microscopic immunocytochemical study","volume":"86","author":"Liposits","year":"1987","journal-title":"Histochemistry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB74","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1001\/archpsyc.1989.01810070067011","article-title":"Augmented pituitary corticotropin response to a threshold dosage of human corticotropin-re-leasing hormone in depressives treated with metyrapone","volume":"46","author":"Lisansky","year":"1989","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB75","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0006-8993(94)90932-6","article-title":"Brain 5-HT2 receptors in suicide victims: violence of death, depression and effects of antidepressant treatment","volume":"642","author":"Lowther","year":"1994","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB76","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0149-7634(94)90039-6","article-title":"Antidepressant-like behavioral effects of serotonin receptor agonists","volume":"18","author":"Lucki","year":"1994","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB77","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-0447.1990.tb06443.x","article-title":"Suppressant effects of dexamethasone on the availability of plasma 1-tryptophan and tyrosine in healthy controls and in depressed patients","volume":"81","author":"Maes","year":"1990","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB78","series-title":"Psychopharmacology: The Fourth Generation of Progress","first-page":"1","article-title":"The serotonin hypothesis of major depression","author":"Maes","year":"1995"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB79","series-title":"Neurobiological Mechanisms of Adaptation and Behavior","article-title":"Neurobiological mechanisms of presynaptic metabolic adaptation and their organization: implications for a pathophysiology of the affective disorders","author":"Mandell","year":"1975"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB80","first-page":"174","article-title":"Demonstrations in vivo of reduced serotonin responsivity in the brain of untreated depressed patients","volume":"153","author":"Mann","year":"1996","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB81","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1001\/archpsyc.1986.01800100048007","article-title":"Increased serotonin2 and \u03b2-adrenergic receptor binding in the frontal cortices of suicide victims","volume":"43","author":"Mann","year":"1986","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB82","first-page":"60","article-title":"Evidence for involvement of 5-hydroxytryptamine receptors in antide-pressant-like drug effects on differential-reinforcement-of-low-rate 72-second behavior","volume":"250","author":"Marek","year":"1989","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB83","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF01244944","article-title":"Serotonergic measures in suicide brain; 5-HT1a binding sites in frontal cortex of suicide victims","volume":"85","author":"Matsubara","year":"1991","journal-title":"J Neural Transm Gen Sect"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB84","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/0006-3223(93)90011-2","article-title":"Acute tryptophan depletion in autistic disorder: a controlled case study","volume":"33","author":"McDougle","year":"1993","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB85","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0165-0327(87)90075-9","article-title":"5-HT receptor binding in post-mortem brain from patients with affective disorder","volume":"13","author":"McKeith","year":"1987","journal-title":"J Affect Disord"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB86","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/0006-3223(94)00152-S","article-title":"Serotonin receptor binding in a colony model of chronic social stress","volume":"37","author":"McKittrick","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB87","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1159\/000125287","article-title":"Neonatal handling alters adrenocortical negative feedback sensitivity and hippocampal type II glucocorticoid receptor binding in the rat","volume":"50","author":"Meaney","year":"1989","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB88","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1176\/ajp.151.10.1485","article-title":"Low CSF 5-HIAA concentrations and severe aggression and impaired impulse control in nonhuman primates","volume":"151","author":"Mehlmann","year":"1994","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB89","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1176\/ajp.152.6.907","article-title":"Correlation of CSF 5-HIAA concentration with sociality and the timing of emigration in free-ranging primates","volume":"152","author":"Mehlmann","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB90","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0922-4106(94)90134-1","article-title":"Corticosterone suppresses the expression of 5-HT1a receptor mRNA in rat dentate gyrus","volume":"266","author":"Meijer","year":"1994","journal-title":"Eur J Pharmacology Mol Pharmacol Sect"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB91","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/0006-3223(94)00132-M","article-title":"CRH challenge test in anxious depression","volume":"37","author":"Meller","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB92","first-page":"353","article-title":"Adrenalectomy increases the density of 5-HT1a receptors in rat hippocampus","volume":"12","author":"Mendelson","year":"1990","journal-title":"Neuroendocrinol Lett"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB93","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0006-3223(94)00150-2","article-title":"The psychotropic effects of inhibitors of steroid biosynthesis in depressed patients refractory to treatment","volume":"37","author":"Missagh Ghadirian","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB94","first-page":"121","article-title":"Response to steroid suppression in major depression resistant to antidepressant therapy","volume":"11","author":"Murphy","year":"1991","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB95","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1126\/science.6334362","article-title":"Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients","volume":"226","author":"Nemeroff","year":"1984","journal-title":"Science"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB96","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1001\/archpsyc.1994.03950010034005","article-title":"Suicidality and 5-hydroxy-indoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism","volume":"51","author":"Nielsen","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB97","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1600-0447.1980.tb00576.x","article-title":"Resistance to inhibiting effect of dexamethasone in patients with endogenous depression","volume":"61","author":"Nuller","year":"1980","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB98","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0165-0327(94)00082-K","article-title":"Treatment of a major depression with metyrapone and hydrocortisone","volume":"33","author":"O'Dwyer","year":"1995","journal-title":"J Affect Disord"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB99","first-page":"944s","article-title":"Serotonin receptor subtypes and aggressive behaviour","volume":"10","author":"Olivier","year":"1994","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB100","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0014-2999(90)94118-H","article-title":"Effects of 5-HT1a receptor agonists on hypothalamo-pituitary-adrenal axis activity and corticotropin-releasing factor containing neurons in the rat brain","volume":"190","author":"Owens","year":"1990","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB101","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0006-3223(90)90576-N","article-title":"Platelet serotonin-2 receptor binding sites in depression and suicide","volume":"28","author":"Pandey","year":"1990","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB102","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1001\/archpsyc.1971.01750160052010","article-title":"Scaling of life events","volume":"24","author":"Paykel","year":"1971","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB103","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1111\/j.2042-7158.1992.tb05521.x","article-title":"Stimulation of postsynaptic 5-HT1a receptors is responsible for the anticonflict effect of ipsapirone in rats","volume":"44","author":"Przegalinski","year":"1992","journal-title":"J Pharm Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB104","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1159\/000126778","article-title":"Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients","volume":"60","author":"Raadsheer","year":"1994","journal-title":"Clin Neuroendocrinol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB105","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/0006-8993(85)90445-7","article-title":"Dominant social status facilitates the behavioral effects of serotonergic agonists","volume":"348","author":"Raleigh","year":"1985","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB106","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0006-8993(91)90001-C","article-title":"Serotonergic mechanisms promote dominance acquisition in adult male vervet monkeys","volume":"559","author":"Raleigh","year":"1991","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB107","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0022-4731(86)90063-4","article-title":"Anatomical resolution of two types of corticosterone receptor sites in rat brain with in vitro autoradiography and computerized image analysis","volume":"24","author":"Reul","year":"1986","journal-title":"J Steroid Biochem"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB108","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1159\/000126788","article-title":"Hypothalamic-pituitary-adrenocortical axis changes in the rat after long-term treatment with the reversible monoamine oxidase-A inhibitor moclobemide","volume":"60","author":"Reul","year":"1994","journal-title":"Neuroendocrinology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB109","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1210\/mend-3-10-1674","article-title":"Type I and type II corticosteroid receptor gene expression in the rat: effect of adrenalectomy and dexamethasone administration","volume":"3","author":"Reul","year":"1989","journal-title":"Mol Endocrinol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB110","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1210\/en.133.1.312","article-title":"Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adreno-cortical system","volume":"133","author":"Reul","year":"1993","journal-title":"Endocrinology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB111","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0006-3223(94)91252-1","article-title":"Adverse early experiences affect noradrenergic and serotonergic functioning in adult primates","volume":"35","author":"Rosenblum","year":"1994","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB112","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0165-3806(88)90206-4","article-title":"Ontogeny of type I and type II corticosteroid receptors in the rat hippocampus","volume":"42","author":"Rosenfeld","year":"1988","journal-title":"Dev Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB113","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0165-1781(88)90061-3","article-title":"Acting out hostility in normal volunteers: negative correlation with levels of 5-HIAA in cerebrospinal fluid","volume":"24","author":"Roy","year":"1988","journal-title":"Psychiatry Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB114","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1001\/archpsyc.1995.03950150045009","article-title":"Adrenal gland volume in major depression","volume":"52","author":"Rubin","year":"1995","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB115","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/0006-3223(91)90252-H","article-title":"Disturbed glucocorticoid receptor autoregulation and corticotropin response to dexamethasone in depressives pretreated with metyrapone","volume":"29","author":"Rupprecht","year":"1991","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB116","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0165-0327(90)90003-Q","article-title":"Plasma tryptophan to large neutral amino acid ratios in depressed and normal subjects","volume":"19","author":"Russ","year":"1990","journal-title":"J Affect Disord"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB117","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1001\/archpsyc.1973.01750310011002","article-title":"Disrupted 24-hour patterns of cortisol secretion in psychotic depression","volume":"28","author":"Sachar","year":"1973","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB118","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0014-2999(94)00470-6","article-title":"Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1a receptors","volume":"264","author":"Sanchez","year":"1994","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB119","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0006-8993(90)91761-5","article-title":"Serotonin release varies with brain tryptophan levels","volume":"532","author":"Schaechter","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB120","first-page":"1335","article-title":"Alterations of central serotonergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies","volume":"255","author":"Schlechter","year":"1990","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB121","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF00445572","article-title":"Anti-conflict efficacy of buspirone following acute vs. chronic treatment","volume":"99","author":"Schefke","year":"1989","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB122","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0014-2999(93)90531-L","article-title":"Neuronal circuits involved in the anxiolytic effects of the 5-HT1a receptor agonists 8-OH-DPATm ipsapirone and buspirone in the rat","volume":"249","author":"Schreiber","year":"1993","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB123","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/00008877-199312000-00008","article-title":"Neuroanatomical basis for the antidepressant-like effects of the 5-HT1a receptor agonists 8-OH-DPAT and ipsapirone in the rat forced swimming test","volume":"4","author":"Schreiber","year":"1993","journal-title":"Behav Pharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB124","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0960-0760(91)90291-C","article-title":"Use of in situ hybridization to investigate the regulation of hippocampal corticosteroid receptors by monoamines","volume":"40","author":"Seckl","year":"1991","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB125","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0163-1047(80)91005-5","article-title":"Neurochemical basis of the action of antidepressants on learned helplessness","volume":"30","author":"Sherman","year":"1980","journal-title":"Behav Neur Biol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB126","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0028-3908(93)90153-T","article-title":"Antidepressant-like activity of compounds with varying efficacy at 5-HT1a receptors","volume":"32","author":"Singh","year":"1993","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB127","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0006-8993(86)91581-7","article-title":"Brain serotonin and catecholamine responses to repeated stress in rats","volume":"367","author":"Souza","year":"1986","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB128","series-title":"Serotonin 1A Receptors","author":"Stahl","year":"1992"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB129","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0140-6736(83)92590-4","article-title":"Increased serotonin-2 binding sites in frontal cortex of suicide victims","volume":"i","author":"Stanley","year":"1983","journal-title":"Lancet"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB130","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/0024-3205(85)90242-5","article-title":"Correlations between aminergic metabolites simultaneously obtained from human CSF and brain","volume":"37","author":"Stanley","year":"1985","journal-title":"Life Sci"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB131","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1192\/bjp.149.1.7","article-title":"The relationship of anxiety and depression: a review of the literature","volume":"149","author":"Stavrakaki","year":"1986","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB132","first-page":"9","article-title":"Serum tryptophan levels in patients with endogenous depression. I. Differences between unipolar and bipolar forms of affective disorder","volume":"10","author":"Taracha","year":"1994","journal-title":"N Trends Exp Clin Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB133","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/0006-3223(94)00137-R","article-title":"Cortisol synthesis inhibition: a new treatment strategy for the clinical and endocrine manifestations of depression","volume":"37","author":"Thakore","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB134","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/0006-8993(90)91138-7","article-title":"Adrenergic regulation of [3H]ketanserin binding sites during immobilization stress in the rat frontal cortex","volume":"527","author":"Torda","year":"1990","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB135","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1600-0447.1984.tb02503.x","article-title":"CSF monoamine metabolites of depressed patients during illness and after recovery","volume":"69","author":"Tr\u00e4skman-Bendz","year":"1984","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB136","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1097\/00004850-199510030-00003","article-title":"Cerebrospinal fluid 5-hydroxyindolacetic acid and aggression; a critical reappraisal of the clinical data","volume":"10","author":"Tuinier","year":"1995","journal-title":"Im Clin Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB137","first-page":"101","article-title":"Significance of biochemical parameters in the diagnosis, treatment and prevention of depressive disorders","volume":"12","author":"Van Praag","year":"1977","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB138","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1017\/S0767399X00002479","article-title":"Serotonergic mechanisms and suicidal behavior","volume":"3","author":"Van Praag","year":"1988","journal-title":"Psychiatr Psychobiol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB139","first-page":"375","article-title":"Diagnosing depression \u2014 looking backward into the future","volume":"7","author":"Van Praag","year":"1989","journal-title":"Psychiatr Dev"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-1781(90)90053-8","article-title":"Two-tier diagnosing in psychiatry","volume":"34","author":"Van Praag","year":"1990","journal-title":"Psychiatry Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB141","series-title":"Make Believes in Psychiatry or the Perils of Progress","author":"Van Praag","year":"1992"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB142","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0924-977X(92)90001-O","article-title":"About the centrality of mood lowering in mood disorders","volume":"2","author":"Van Praag","year":"1992","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB143","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1192\/bjp.160.2.266","article-title":"Reconquest of the subjective. Against the waning of psychiatric diagnosing","volume":"160","author":"Van Praag","year":"1992","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB144","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/00004850-199403001-00002","article-title":"5-HT related, anxiety- and\/or aggression-driven depression","volume":"9","author":"Van Praag","year":"1994","journal-title":"Int Clin Psychopharmacol"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB145","series-title":"International Academy of Biomedical Drug Research","first-page":"144","article-title":"Anxiety and aggression as pacemakers of depression: a dimensional variation of the serotonin hypothesis of depression","author":"Van Praag","year":"1994"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB146","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0924-9338(96)80307-5","article-title":"Concerns about depression","volume":"10","author":"Van Praag","year":"1995","journal-title":"Eur Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB147","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0924-9338(96)84782-1","article-title":"Serotonin-related, anxiety\/aggression-driven, stressor-precipitated depression. A psycho-biological hypothesis","volume":"11","author":"Van Praag","year":"1996","journal-title":"Eur Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB148","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1192\/bjp.157.5.723","article-title":"Monoamines and abnormal behavior. A multi-aminergic perspective","volume":"157","author":"Van Praag","year":"1990","journal-title":"Br J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB149","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/acps.1980.61.s280.89","article-title":"Central serotonin deficiency. A factor which increases depression vulnerability?","volume":"61","author":"Van Praag","year":"1980","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB150","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0165-1781(80)90049-9","article-title":"Depression vulnerability and 5-hydroxytryptophan prophylaxis","volume":"3","author":"Van Praag","year":"1980","journal-title":"Psychiatry Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB151","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0327(87)90067-X","article-title":"Denosologization of biological psychiatry or the specificity of 5-HT disturbances in psychiatric disorders","volume":"13","author":"Van Praag","year":"1987","journal-title":"J Affect Disord"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB152","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1038\/2251259b0","article-title":"5-Hydroxin-doleacetic acid levels in the cerebrospinal fluid of depressive patients treated with probenecid","volume":"225","author":"Van Praag","year":"1970","journal-title":"Nature"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB153","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1001\/archpsyc.1994.03950010020003","article-title":"CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters and healthy volunteers","volume":"51","author":"Virkkunen","year":"1994","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB154","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0006-8993(93)91117-B","article-title":"Stress and antidepressant effects on hippocampal and cortical 5-HT1a and 5-HT2 receptors and transport sites for serotonin","volume":"615","author":"Watanabe","year":"1993","journal-title":"Brain Res"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB155","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0165-0173(81)90005-9","article-title":"Behavioral depression produced by an uncontrollable Stressor: relationship to norepinephrine, dopamine, and serotonin levels in various regions of rat brain","volume":"3","author":"Weiss","year":"1981","journal-title":"Brain Res Rev"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB156","first-page":"918","article-title":"Central and peripheral mechanisms in the stimulation of adrenocortical secretion by the 5-hydroxytryptamine2 agonist, (\u00b1)-1(2,5-dimethoxy-4-lodophenyl)-2-aminopropane","volume":"270","author":"Welch","year":"1994","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB157","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/syn.890040410","article-title":"Autoradiographic quantification of serotonin 1a receptors in rat brain following antidepressant drug treatment","volume":"4","author":"Welner","year":"1989","journal-title":"Synapse"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB158","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0091-3057(91)90155-U","article-title":"Effects of serotonergic agents on isolation-induced aggression","volume":"39","author":"White","year":"1991","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB159","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1176\/ajp.150.5.810","article-title":"Ketoconazole administration in hypercortisolemic depression","volume":"150","author":"Wolkowitz","year":"1993","journal-title":"Am J Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB160","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF02246047","article-title":"Acute immobilization stress reduces (\u00b1)DOI-induced 5-HT2a receptor-mediated head shakes in rats","volume":"119","author":"Yamada","year":"1995","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB161","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0006-3223(90)90440-D","article-title":"5-HT2 Receptor changes in major depression","volume":"27","author":"Yates","year":"1990","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB162","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1007\/BF02244859","article-title":"Effects of glucocorticoids on 5-HT1a presynaptic function in the mouse","volume":"114","author":"Young","year":"1994","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB163","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0028-3908(92)90080-9","article-title":"The effects of corticosterone on 5-HT receptor function in rodents","volume":"31","author":"Young","year":"1992","journal-title":"Neuropharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB164","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0165-0327(94)90072-8","article-title":"Effects of hydrocortisone on brain 5-HT function and sleep","volume":"32","author":"Young","year":"1994","journal-title":"J Affect Disord"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB165","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0006-3223(94)00153-T","article-title":"Evidence against changes in corticotroph CRF receptors in depressed patients","volume":"37","author":"Young","year":"1995","journal-title":"Biol Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB166","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/archpsyc.1991.01810320017003","article-title":"Loss of glucocorticoid fast feedback in depression","volume":"48","author":"Young","year":"1991","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB167","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/BF00431803","article-title":"Tryptophan depletion causes a rapid lowering of mood in normal males","volume":"87","author":"Young","year":"1985","journal-title":"Psychopharmacology"},{"key":"10.1016\/S0165-1781(96)02923-X_BIB168","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0893-133X(94)00085-E","article-title":"The gene encoding the 5-HT1a receptor is intact in mood disorders","volume":"12","author":"Xie","year":"1995","journal-title":"Neuropsychopharmacology"}],"container-title":["Psychiatry Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016517819602923X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016517819602923X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T05:12:43Z","timestamp":1620882763000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016517819602923X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,12]]},"references-count":168,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,12]]}},"alternative-id":["S016517819602923X"],"URL":"https:\/\/doi.org\/10.1016\/s0165-1781(96)02923-x","relation":{},"ISSN":["0165-1781"],"issn-type":[{"value":"0165-1781","type":"print"}],"subject":[],"published":{"date-parts":[[1996,12]]}}}