{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T22:10:22Z","timestamp":1655503822024},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,4,1]],"date-time":"2001-04-01T00:00:00Z","timestamp":986083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computer Methods and Programs in Biomedicine"],"published-print":{"date-parts":[[2001,4]]},"DOI":"10.1016\/s0169-2607(00)00115-2","type":"journal-article","created":{"date-parts":[[2002,7,25]],"date-time":"2002-07-25T19:50:50Z","timestamp":1027626650000},"page":"79-87","source":"Crossref","is-referenced-by-count":2,"title":["Three-dimensional visualization of lung blood flow heterogeneity based on fluorescent microsphere technique and fractal dimension: The Blood Flow Analysis System \u2014 BFA System"],"prefix":"10.1016","volume":"65","author":[{"given":"D.A.","family":"Bottino","sequence":"first","affiliation":[]},{"given":"M.","family":"Kleen","sequence":"additional","affiliation":[]},{"given":"G.","family":"Kemming","sequence":"additional","affiliation":[]},{"given":"F.","family":"Meisner","sequence":"additional","affiliation":[]},{"given":"O.","family":"Habler","sequence":"additional","affiliation":[]},{"given":"K.","family":"Messmer","sequence":"additional","affiliation":[]}],"member":"78","reference":[{"key":"10.1016\/S0169-2607(00)00115-2_BIB1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0022-4804(84)90185-9","article-title":"The radiolabeled microsphere technique in gut blood flow measurement-current practice","volume":"37","author":"Levine","year":"1984","journal-title":"J. Surg. Res."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0895-6111(90)90135-X","article-title":"Pseudocolor display of regional organ blood flow determined by means of the radioactive microsphere technique","volume":"14","author":"Gross","year":"1990","journal-title":"Comput. Medical Imaging Graphics"},{"key":"10.1016\/S0169-2607(00)00115-2_BIB3","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1152\/jappl.1987.63.2.883","article-title":"Regional trapping of microspheres in the lung compares well with regional blood flow","volume":"63","author":"Beck","year":"1987","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0008-6363(95)00060-7","article-title":"Fluorescent vs. radioactive microsphere measurement of regional myocardial blood flow","volume":"30","author":"Chien","year":"1995","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB5","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1093\/cvr\/28.10.1467","article-title":"Development in non-radioactive microsphere techniques for blood flow measurement","volume":"28","author":"Prinzen","year":"1994","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB6","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1152\/jappl.1993.74.5.2585","article-title":"Validation of fluorescent-labeled microspheres for measurement of regional organ perfusion","volume":"74","author":"Glenny","year":"1993","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB7","first-page":"H725","article-title":"Fluorescent microspheres to measure organ perfusion: validation of a simplified sample processing technique","volume":"269","author":"Van Oosterhout","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB8","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1515\/bmte.1998.43.s1.536","article-title":"Validierung eines roboters zur bestimmung der regionalen perfusion mittels fluoreszierender mikrosph\u00e4ren","volume":"43","author":"Thein","year":"1998","journal-title":"Biomedizinische Technik"},{"key":"10.1016\/S0169-2607(00)00115-2_BIB9","first-page":"1341","article-title":"Distribution of blood flow in isolated lung: relation to vascular and alveolar pressures","volume":"55","author":"West","year":"1964","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB10","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1152\/jappl.1992.72.6.2378","article-title":"Spatial correlation of regional pulmonary perfusion","volume":"72","author":"Glenny","year":"1992","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB11","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1152\/jappl.1995.79.3.986","article-title":"Temporal heterogeneity of regional pulmonary perfusion is spatially clustered","volume":"79","author":"Glenny","year":"1995","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB12","doi-asserted-by":"crossref","first-page":"8S, S16","DOI":"10.1378\/chest.114.1_Supplement.8S","article-title":"Blood flow distribution in the lung","volume":"114","author":"Glenny","year":"1998","journal-title":"Chest"},{"key":"10.1016\/S0169-2607(00)00115-2_BIB13","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1152\/jappl.1996.80.2.430","article-title":"Distribution of pulmonary and bronchial blood supply to airways measured by fluorescent microspheres","volume":"80","author":"Bernard","year":"1996","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB14","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1152\/jappl.1987.63.3.1114","article-title":"Gravity-independent inequality in pulmonary blood flow in humans","volume":"63","author":"Hakim","year":"1987","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB15","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1152\/jappl.1990.69.2.532","article-title":"Fractal properties of pulmonary blood flow: characterization of spatial heterogeneity","volume":"69","author":"Glenny","year":"1990","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB16","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/BF01951755","article-title":"The fractal lung: universal and species-related scaling patterns","volume":"46","author":"Nelson","year":"1990","journal-title":"Experientia"},{"key":"10.1016\/S0169-2607(00)00115-2_BIB17","series-title":"The Fractal Geometry of Nature","author":"Mandelbrot","year":"1983"},{"key":"10.1016\/S0169-2607(00)00115-2_BIB18","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1152\/jappl.1994.77.3.1474","article-title":"Effects of pulmonary blood flow on the fractal nature of flow heterogeneity in sheep lungs","volume":"77","author":"Caruthers","year":"1994","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB19","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1152\/jappl.1991.70.6.2351","article-title":"Applications of fractal analysis to physiology","volume":"70","author":"Glenny","year":"1991","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/jappl.1991.71.1.1","article-title":"Fractal perspectives in pulmonary physiology","volume":"71","author":"Mcnamee","year":"1991","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB21","first-page":"37","article-title":"Heterogeneity of left ventricular perfusion during pulmonary edema and microembolism treated with positive end expiratory pressure and norepinephrine","volume":"26","author":"Vidal-Melo","year":"1993","journal-title":"Brazilian J. Med. Biol. Res."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB22","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1161\/01.RES.65.3.578","article-title":"A fractal nature of regional myocardial blood flow heterogeneity","volume":"65","author":"Bassingthwaighte","year":"1989","journal-title":"Circ. Res."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB23","first-page":"H1670","article-title":"Regional myocardial flow heterogeneity explained with fractal networks","volume":"257","author":"Van Beek","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB24","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0169-2607(97)00047-3","article-title":"Programs for assessment of spatial heterogeneity of regional organ blood flow","volume":"55","author":"Kleen","year":"1998","journal-title":"Comput. Methods Programs Biomed."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB25","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1152\/jappl.1997.83.4.1370","article-title":"Vascular tree structure affects lung blood flow heterogeneity simulated in three dimensions","volume":"83","author":"Parker","year":"1997","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB26","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1152\/jappl.1995.79.1.357","article-title":"A computer simulation of pulmonary perfusion in three dimensions","volume":"79","author":"Glenny","year":"1995","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB27","unstructured":"A. Stevenson, Voxels and volumetric representation. The University of British Columbia, Canada. http:\/\/www.intergate.bc.ca\/personal\/sagax\/voxels\/voxels.htm. Last updated 20\/03\/1998."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB28","unstructured":"E. Catmull, Subdivision Algorithm for computer display of curved surfaces, Thesis, report UTEC-CSc-74-133, Computer Science Department, University of Utah, Salt Lake City, UT, December, 1974."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB29","unstructured":"J.D. Foley, A. Vam Dam, S.K. Feiner, J.F. Hughes, Algorithms for visible-line determination, in: Computer Graphics. Principles and Practice, P.S. Gordon (Ed.), Addison-Wesley Publishing Company, Massachusetts, USA, 1996, pp. 665\u2013672."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB30","unstructured":"M.M.B. Holl, Matrix Notation for Geometric Transformations, http:\/\/gc166-410.chem.brown.edu\/chem50\/Notes\/matrix-notation.html. Last updated 16\/08\/1999."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB31","unstructured":"C.K. Shene, Michigan Technological University, Department of Computer Science, Geometric Transformations, http:\/\/www.csl.mtu.edu\/cs390-2\/www\/NOTES\/geometry\/geo-tran.html. Last updated 15-08-1999."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB32","unstructured":"R.W. Glenny, Manual for using fluorescent microspheres to measure regional organ perfusion. Fluorescent Microsphere Resource Center. University of Washington, 1996."},{"key":"10.1016\/S0169-2607(00)00115-2_BIB33","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1152\/jappl.1996.81.5.2039","article-title":"Measurement of pulmonary blood flow by fractal analysis of flow heterogeneity in isolated canine lungs","volume":"81","author":"Barman","year":"1996","journal-title":"J. Appl. Physiol."}],"container-title":["Computer Methods and Programs in Biomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169260700001152?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0169260700001152?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T17:44:44Z","timestamp":1579110284000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0169260700001152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,4]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,4]]}},"alternative-id":["S0169260700001152"],"URL":"https:\/\/doi.org\/10.1016\/s0169-2607(00)00115-2","relation":{},"ISSN":["0169-2607"],"issn-type":[{"value":"0169-2607","type":"print"}],"subject":[],"published":{"date-parts":[[2001,4]]}}}